Digital Commons Network^™

Comparative Analysis Of Prostate Cancer Gene Regulatory Networks Via Hub Type Variation, Pegah Khosravi, Vahid H. Gazestani, Mohammad Akbarzadeh, Samira Mirkhalaf, Mehdi Sadeghi, Bahram Goliaei

Publications and Research

Background

Prostate cancer is one of the most widespread cancers in men and is fundamentally a genetic disease. Identifying regulators in cancer using novel systems biology approaches will potentially lead to new insight into this disease. It was sought to address this by inferring gene regulatory networks (GRNs). Moreover, dynamical analysis of GRNs can explain how regulators change among different conditions, such as cancer subtypes.

Methods

In our approach, independent gene regulatory networks from each prostate state were reconstructed using one of the current state-of-art reverse engineering approaches. Next, crucial genes involved in this cancer were highlighted by analyzing each …

Peers Inspiring Peers: Why A Summer Bridge-To-College Program Benefits From This Partnership, Janet Liou-Mark, A.E. Dreyfuss, Mursheda Ahmed, Christopher Chan, Karmen Yu

Publications and Research

A Bridge-to-College Summer Academy for Teaching Assistant Scholars, who serve as Peer Leaders and small-group instructors in several New York City high schools, was designed and held at New York City College of Technology, CUNY. The Summer Academy was designed to acclimate the Teaching Assistant Scholars (TAS), many of whom are underrepresented minority students, to college life. College Peer Leaders assisted in motivating and encouraging incoming freshmen in gaining the academic skills needed to successfully navigate a college environment. The Peer Leaders also facilitated three-day mathematics preparatory workshops that provided students with the confidence to excel in their first credit-bearing …

Brewing Behind Barbed Wire: An Archaeology Of Saké At Amache, Christian Driver

Electronic Theses and Dissertations

After the Japanese attack at Pearl Harbor on December 7, 1941, approximately 120,000 people of Japanese ancestry living on the west coast of the United States were forcibly removed from their home communities. These people were designated as "evacuees" by the U.S. Government and were incarcerated within a network of federal government facilities the largest of which were internment centers operated by the War Relocation Authority that held mostly U.S. citizens. The Granada Relocation Center (Amache) was the smallest of these internment centers. The presence of saké at Amache indicates that Japanese Americans continued important practices of daily life despite …

Student-Athlete Learning: How Learning Spaces Influence Athletic And Academic Success, Kelli A. Logan

Electronic Theses and Dissertations

This study will utilize case study inquiry to examine student-athlete learning opportunities in the athletic learning space and academic learning space in a higher education NCAA Division I collegiate institution. This study will assess what learning opportunities exist within the athletic and academic learning space to better understand effective learning practices. This study will utilize the sociocultural Learning Sciences literature, supported with critical pedagogy and inclusive excellence literature, to understand how different learning spaces contribute to student-athlete learning opportunities and educational success in college.

Environmental Federalism’S Tug Of War Within, Erin Ryan

Scholarly Publications

The intensity of federalism disputes reflects inexorable pressure on all levels of government to meet the increasingly complicated challenges of governance in an ever more interconnected world. Yet even as federalism dilemmas continue to erupt all from all corners, environmental law remains at the forefront of controversy. This chapter argues that environmental law is uniquely prone to federalism discord because it inevitably confronts the core question with which federalism grapples — who gets to decide? — in contexts where state and federal claims to power are simultaneously at their strongest. Environmental problems tend to match the need to regulate the …

The Public Trust Doctrine, Private Water Allocation, And Mono Lake: The Historic Saga Of National Audubon Society V. Superior Court, Erin Ryan

Scholarly Publications

This article tells the epic tale of the fall and rise of Mono Lake — the strange and beautiful Dead Sea of California — which fostered some of the most important environmental law developments of the last century, and which has become a platform for some of the most potentially important developments in the new century. It shares the backstory and legacy of the California Supreme Court’s famous decision in National Audubon Society v. Superior Court, 658 P.2d 709 (Cal. 1983), known more widely as “the Mono Lake case.” Inspired by innovative legal scholarship and advocacy, the decision spawned a …

The Dual Role Of Self-Enhancement : Protection And Stigma, Corina Evelyn Klein

Dissertations and Theses @ UNI

Despite the availability of effective treatment options for posttraumatic stress disorder (PTSD), these treatments are highly under-utilized. One of the most cited barriers to treatment among people with PTSD symptoms is public stigma. In fact, the majority of the population experiences a potentially traumatic event (PTE) in their lifetime and should contribute to an assumption of a lack of stigma toward people with PTSD symptoms. Yet, it may be that the stigma perceived by people with PTSD symptoms is more nuanced than what is seen in stigma for other disorders. More often than not, people who experience a PTE will …

“God Will Deliver Us” : Human Rights Abuses From Guatemala To Iowa And Back, 1980-2014, Raeann Lillian Swanson

Dissertations and Theses @ UNI

Guatemala’s long internal conflict, the lack of justice, the general poverty, and continued violence since the signing of the 1996 Peace Accords prompt many people to migrate to the United States in search of jobs and opportunities for their family. Since the 1980s, Guatemalans have settled in Postville, Iowa, a small town that is nationally recognized for the ethnically diverse populations that live and work there. In 2008, it was also the site of the largest Immigration Customs Enforcement (ICE) worksite raid to date and the following criminal trials were unprecedented. Because of the tragedy in Postville, sources that detail …

Caged Manhood : Office Culture And How Walter Camp's Daily Dozen Revitalized The Workforce, 1903-1940, Nick Sly

Dissertations and Theses @ UNI

This thesis is examines how culture became a means to deal with the problems of over-civilization in the early twentieth century. The realities of a salaried position and corporate work spaces had dramatically changed how the middle class felt about work. Looking at the writings of Walter Camp, the human relations movement, and the exercise culture of the period one can see how the office space was not simply a place of work but a new context for constructing masculinity and a sense of worth.

In Connection With All Things : The Memory Of Alexander Humboldt And His Works In The Context Of 19th Century Thought In Europe And America, Ray Joseph Werner

Dissertations and Theses @ UNI

This thesis explores the memory of Alexander von Humboldt, the explorer and philosopher who was known for his travels throughout Europe, Asia, South America, and North America. This paper will examine primary and secondary sources throughout the 19^th and 20^th centuries that mark a change in just how Humboldt was remembered, once as a great thinker, philosopher, and romanticist, then eventually as little more than an empirical scientist. This thesis will contribute to modern understandings of this man by looking at popular publications and writings that track this change over time. It will contribute to the modern understanding …

Perceived Effects Of Family Status Changes On Male Collegiate Outdoor Recreation Coordinators, Andrew K. Martin

Dissertations and Theses @ UNI

A career as a collegiate outdoor recreation professional is both a challenging and rewarding occupation. It is a position that consists of inconsistent hours as well as extended periods away from home. This qualitative study identified how changes in family status affect an individual’s perception of the position as a collegiate outdoor recreation coordinator. More specifically, the perceived benefits or challenges that occur throughout the family status changes, and what effect, if any, these perceptions had on the individual’s work performance, job satisfaction and career longevity.

Using a phenomenological approach, semi-structured interviews were conducted with eight individuals who were employed …

Biomechanics Of Lower Limbs During Walking Among Candidates For Total Knee Arthroplasty With And Without Low Back Pain, David R. Burnett, Naira H. Campbell-Kyureghyan, Robert V. Topp, Peter M. Quesada

College of Nursing Faculty Research and Publications

The effect of joint pathologies, such as unilateral knee osteoarthritis (UKOA) or low back pain (LBP), on bilateral gait symmetry has gained increased attention during the past decade. This study is the first to compare gait patterns between patients with UKOA and LBP in combination and with UKOA only. Temporal, kinematic, and kinetic variables were measured bilaterally during gait stance phase in 31 subjects with UKOA and LBP (Group I) and 11 subjects with only UKOA (Group II). Group I patients exhibited less hip rotation in the affected limb (A) than in the nonaffected (NA) limb during walking in contrast …

Evidence For Respiratory Neuromodulator Interdependence After Cholinergic Disruption In The Ventral Respiratory Column, Clarissa Muere, Suzanne Neumueller, Justin Robert Miller, Samantha Olesiak, Matthew Hodges, Lawrence Pan, Hubert Forster

Physical Therapy Faculty Research and Publications

Reverse dialysis of the muscarinic receptor antagonist, atropine (ATR, 50 mM), into the pre-Bötzinger Complex region of the ventral respiratory column (VRC) of awake and sleeping goats increases breathing frequency and serotonin (5-HT), substance P (SP), glycine, and GABA concentrations in the effluent dialysate. Herein, we report data from goats in which we reverse dialyzed 5 mM ATR or specific antagonists of M2 or M3 muscarinic receptors into the VRC. The effects on frequency of all three antagonists were not significantly different from time control studies. 5 mM ATR and the M3 antagonist increased SP sevenfold less than 50 mM …

Studying Air Pollutants Origin And Associated Meteorological Parameters Over Seoul From 2000 To 2009, Sunmin Park, Hesham El-Askary, Ismail Sabbah, Hanbin Kwak, Anup K. Prasad, Woo-Kyun Lee, Menas Kafatos

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

We investigate the temporal characteristics of major air pollutants collected from 44 air quality stations over the city of Seoul, Korea, namely, nitrogen dioxide, carbon monoxide, particular matter at 10 microns, and sulfur dioxide (SO2) between 2000 and 2009. The corresponding satellite datasets, namely, aerosol optical depth (AOD_sat), Ångström exponent, and fine mode fraction, collected from moderate resolution imaging spectroradiometer (MODIS) as well as the Aeronet ground aerosol optical depth (AOD_aeronet), have been analyzed. Pollutants’ seasonal effect has been inferred from the precipitation and temperature. The four pollutants under study show varying temporal characteristics with different …

Family Involvement In Picu Rounds, Lyvonne N. Tume, Jos M. Latour

School of Nursing and Midwifery

In pediatrics, the family are the centre of the child’s life, and crucial to their psychosocial wellbeing and their recovery from illness. Despite the impetus to improve family centered care in pediatric and neonatal intensive care units, practices are not consistent worldwide. In most North American, Antipodean and Northern European PICUs family visitation is not restricted. However, in some countries restrictions still apply to family access, preventing the delivery of family centered care (1, 2). Even if families are present in the PICU, their involvement in medical rounds is often restricted or not encouraged. Yet, between 85 – 100% of …

Development Of Radial Optic Flow Pattern Sensitivity At Different Speeds, Mahesh Raj Joshi, Helle K. Falkenberg

School of Health Professions

No abstract provided.

The Argument For Moving Away From Residential Placement For Most Juvenile Offenders, Marika Dawkins-Cavazos

Criminal Justice Faculty Publications

This paper examines the theoretical and empirical argument or moving away from residential placement for juvenile offenders. To that end, the use ofres1dential placement for Juvenile offenders and incarceration for adult offenders are compared to shed light on the inconsistencies between rhetoric and actual practices as related to the deterrence theory. While residential placement and incarceration are generally regarded as two separate mechanisms, the literature suggests that residential placement is counterproductive and the U.S. must continue to reassess its approach to juvenile offending.

Neural Network Analysis On The Effect Of Heat Fluxes On Greenhouse Gas Emissions From Anaerobic Swine Waste Treatment Lagoon, N. Lovanh, J. Loughrin, M. Rysz, A. I. Quintanar, B. T. Oh, Rezaul Mahmood

School of Natural Resources: Faculty Publications

No abstract provided.

An Investigation Into The Effects Of Different Types Of Exercise On The Maintenance Of Approach Motivation Levels, J. A.S. Lowenstein, K. Wright, A. Taylor, N. J. Moberly

Peninsula Medical School

No abstract provided.

Defining Competence In Obstetric Epidural Anaesthesia For Inexperienced Trainees, E. J. Drake, J. Coghill, J. R. Sneyd

Peninsula Medical School

Background: Cumulative sum (CUSUM) analysis has been used for assessing competence of trainees learning new technical skills. One of its disadvantages is the required definition of acceptable and unacceptable success rates. We therefore monitored the development of competence amongst trainees new to obstetric epidural anaesthesia in a large public hospital. Methods: Obstetric epidural data were collected prospectively between January 1996 and December 2011. Success rates for inexperienced trainees were calculated retrospectively for (1) the whole database, (2) for each consecutive attempt and (3) each trainee's individual overall success rate. Acceptable and unacceptable success rates were defined and CUSUM graphs generated …

'Makin' It Out': The Cost Of Dropping Out Of High School On The Health Status Of Afro-American Women In Urban Slums, Sesa E. Bakenra-Tikande

CMC Senior Theses

“We carry our histories in our bodies, how could we not?” – Nancy Krieger

In the United States and abroad, socioeconomic status (income, education, and occupation) greatly impacts health outcomes for a given population. There is a strong and consistent socioeconomic gradient within health outcomes which has been documented as far back as in Ancient Egypt and China (Krieger, Willains, & Moss, 1997; Liberatos, Link, & Kelsey, 1988) The general trend shows that individuals with higher socioeconomic status generally enjoy lower rates of morbidity (disease) and disability, which can ultimately lead to higher mortality rates (House et al. (1992) and …

"If You Is White, You's Alright....": Stories About Colorism In America, Kimberly Jade Norwood

Scholarship@WashULaw

This Article examines the inefficiencies of Missouri municipal courts that came into sharp focus following the killing of Michael Brown by Officer Darren Wilson in Ferguson, Missouri. Norwood details and expands on her lone dissent in the Final Report of the Municipal Division Work Group—a group created by the Missouri Supreme Court to address the alleged abuses of black and poor residents in Missouri. Norwood argues for consolidating failing municipal courts to create larger, more functional, and just courts.

A Comparative Analysis Of Bicycle Cultures In The United States And The Netherlands, Sydney Stephenson

CMC Senior Theses

This thesis examines the bicycle cultures found in the United States and the Netherlands. The cities of Claremont, California, San Luis Obispo, California, and Groeningen, Netherlands are used as case studies to compare bicycle policies and infrastructure. Bicycle-friendly cities require bicycle master plans that address accessibility, education and promotion, safe infrastructure, and parking. A successful bicycle culture improves a city’s environmental sustainability, health, equity, and access. Most importantly, a safe and convenient bicycle environment builds community interaction.

Brand Obama: How Barack Obama Revolutionized Political Campaign Marketing In The 2008 Presidential Election, Abigail Michaelsen

CMC Senior Theses

In 2008, President Barack Obama was named Advertising Age’s marketer of the year, the first time a politician won such an award. While presidential candidates have always employed marketing tactics in order to communicate their platform and persuade voters to support them, candidate Obama’s marketing campaign completely revolutionized the field. Through an innovative marketing strategy, candidate Barack Obama transformed himself from a mere political unknown in 2004 to a worldwide sensation by the time the general election started in 2008. His calls for “hope and change” and “post-partisanship” captured the hearts of Americans frustrated with failed Bush policy and constant …

It's Worse Than We Think: Why It Matters That We Underestimate Depression, Tess Hubbeling

CMC Senior Theses

This paper will examine specific processes involved within the decision-making process of how to allocate limited health care resources. I will start by discussing how in order to compare and differentiate between health states, we have created ranking systems, based on the health state’s impact on people’s quality of life, which health states need more care, and which can be most effectively treated. We evaluate impact on quality of life by assigning quality weights to years of life lived with that health state, which we call quality-adjusted life years, or QALYs.

Next, I will discuss the problems with assigning quality …

A Psychological Analysis Of Behavioral Consumerism: Advertising, Decision-Making, And Its Implications For Retailers, Grace V. Coburn

CMC Senior Theses

Advertising is a ubiquitous and substantial influence in consumerism, prompting psychological decision-making processes and behavioral consumerism. Selective marketing, advertising, and merchandising can only be successful when the processes within populations are identified and modified to fit the consumer. This paper examines psychological concepts surrounding the complex variables of decision-making. It will discuss relevant literature and empirical evidence that are imperative to further studies of behavioral consumerism. Such concepts that will be examined include: the elaboration likelihood model, regulatory focus theory, paradox of choice, as well as consumer variables such as influences of personality and maximizers versus satisficers. It then addresses …

A Framework For The Pursuit Of Happiness: Personality As It Relates To Subjective Well-Being, Emma B. Ludlum

CMC Senior Theses

This paper is a framework for the pursuit of happiness. It uses psychological data, philosophical theories, and trends in neuroscience to support the idea that anyone can be happy. It first discusses personality psychology, biology of personality, and the relationship between personality and happiness. From there it explains positive illusions and Depressive Realism to show how one can implement both to increase personal happiness.

Let's Talk About Sex: The Failure Of Abstinence-Only Policies In America's Public Schools, Sloan Caldwell

CMC Senior Theses

Sexual education has been a much-debated topic in the United States since it was instated in light of the HIV/AID pandemic of the 1980s. The debate has always centered on the role of sexual education: should it act to objectively relay the facts about sexual health? Or should it be utilized as a moral purveyor of teen’s sexual behavior? During the second Bush Administration it seemed as if the conservative right had won and sexual education adopted a role policing teen’s morality with $1.5 billion in federal funding for abstinence-only education. This study aims to provide evidence against abstinence-only education …

Employee Engagement: Restoring Viability To A Corporate Cliché, Madeline G. Crawford

CMC Senior Theses

Employee engagement has taken over the corporate world. Whether it is the media, consulting firms, business leaders or human resources, everyone is talking about it. Despite the buzz in the corporate world and millions of dollars pumped into the industry, employee engagement has remained relatively unchanged and our comprehension of it is hazy. Examining the concept of employee engagement from conceptualization to present day helps provide a solid understanding of its foundation and where major evolutionary failings occurred. Prompted by Gallup’s takeover of the concept – from packaging, selling, measuring and intervening – the essence of employee engagement has been …

Increasing The High School Graduation Rate Of Native American Students In Public Schools, Sierra M. Gibson

CMC Senior Theses

Native American students obtain the lowest on-time high school graduation rate among all races and ethnicities in the United States. Through an analysis of previously published literature and seven interviews conducted by the author, this paper sets out to identify the key barriers Native students face when working toward their high school diploma. This paper will argue that, together, a history of abusive educational tactics and an institutionally racist policies and practices adopted by the U.S. Department of Education have made it challenging for Native students to complete high school on time.