Digital Commons Network^™

Toll-Like Receptors And Dectin-1, A C-Type Lectin Receptor, Trigger Divergent Functions In Cns Macrophages, John C. Gensel, Yan Wang, Zhen Guan, Kyle A. Beckwith, Kaitlyn J. Braun, Ping Wei, Dana M. Mctigue, Phillip G. Popovich

Spinal Cord and Brain Injury Research Center Faculty Publications

Spinal cord injury (SCI) activates macrophages, endowing them with both reparative and pathological functions. The mechanisms responsible for these divergent functions are unknown but are likely controlled through stochastic activation of different macrophage receptor subtypes. Various danger-associated molecular patterns released from dying cells in the injured spinal cord likely activate distinct subtypes of macrophage pattern recognition receptors, including bacterial toll-like receptors (TLRs) and fungal C-type lectin receptors (e.g., dectin-1). To determine the in vivo consequences of activating these receptors, ligands specific for TLR2 or dectin-1 were microinjected, alone or in combination, into intact spinal cord. Both ligands elicit a florid …

Volume 52, Number 47: July 08, 2015, University Of North Dakota

University Letter Archive

No abstract provided.

Implicit Bias And Capital Decision-Making: Using Narrative To Counter Prejudicial Psychiatric Labels, Sean O'Brien, Kathleen Wayland

Faculty Works

Overreliance on psychiatric diagnostic labels in the defense of death penalty cases risks triggering prejudicial associations in the minds of decision-makers. This article emphasizes the importance of developing a mitigating counter-narrative of the defendant’s life story, based on an extensive longitudinal and developmental investigation of the defendant and his family’s life trajectory. It is the client’s life story, not diagnostic labels, that reveals his humanity. Cognitive psychology provides a useful framework for explaining human perceptions, and how implicit or explicit biases can interfere with the objective interpretation of data in ways that affect judgment and behavior.

Neuronal Interferon Signaling Is Required For Protection Against Herpes Simplex Virus Replication And Pathogenesis, Pamela C. Rosato, David A. Leib

Dartmouth Scholarship

Interferon (IFN) responses are critical for controlling herpes simplex virus 1 (HSV-1). The importance of neuronal IFN signaling in controlling acute and latent HSV-1 infection remains unclear. Compartmentalized neuron cultures revealed that mature sensory neurons respond to IFNβ at both the axon and cell body through distinct mechanisms, resulting in control of HSV-1. Mice specifically lacking neural IFN signaling succumbed rapidly to HSV-1 corneal infection, demonstrating that IFN responses of the immune system and non-neuronal tissues are insufficient to confer survival following virus challenge. Furthermore, neurovirulence was restored to an HSV strain lacking the IFN-modulating gene, γ34.5, despite its expected …

Re-Creating In Nature, Steve Holtrop

Faculty Work Comprehensive List

"Recreation is re-creation - an opportunity to return to or realign with the whole person I was created to be."

Posting about ­­­­­­­­sensing God's presence in nature from In All Things - an online hub committed to the claim that the life, death, and resurrection of Jesus Christ has implications for the entire world.

http://inallthings.org/re-creating-in-nature/

Pre-Med Student Researching Environmental Contaminants In Alligators, University Communications Illinois Wesleyan University

News and Events (Discontinued Series)

No abstract provided.

Convalescent Serum Therapy As Rapid Advance Treatment For Ebola In West Africa, J Bankole Thompson Md, Phd, Patricia F. Mejabi Msc., Olugbenga O. Mejabi Phd, S Ahmed Tejan-Sie Md

International Journal of African Development

The 2014 public health crisis in Guinea, Liberia, and Sierra Leone has brought Ebola Viral Disease (EVD) to everyone’s attention. Discovered in 1976, this deadly disease infrequently struck in remote areas of Africa. This article will critically review the literature and describe the pathobiology, transmission, signs and symptoms, diagnosis, treatment, and prevention of EVDwhich, was predicted by the Centers for Disease Control to potentially infect 1.4 million persons in Liberia and Sierra Leone by January 2015 (“Questions and Answers”, 2014). Thankfully this worst case scenario did not occur and we may be experiencing natural burn out of the outbreak along …

Parts Of The Whole: Quantitative Literacy On A Desert Island, Dorothy Wallace

Numeracy

Some of the specific institutional problems faced by quantitative reasoning courses, programs and requirements arise from the fragile intellectual position of “quantitative reasoning” as an idea, or meme. The process of isolation and reintroduction explains both the proliferation of living species and the way in which some difficult ideas take their place in a culture. Using evolutionary explanations as metaphor and the Copernican revolution as an example of a difficult idea, we draw lessons that can be applied to the “quantitative reasoning” meme, including the function of the National Numeracy Network as an island of protected discourse favoring the growth …

Review Of Developing Quantitative Literacy Skills In History And The Social Sciences: A Web-Based Common Core Approach By Kathleen W. Craver, Victor J. Ricchezza, H L. Vacher

Numeracy

Kathleen W. Craver. Developing Quantitative Literacy Skills in History and Social Sciences: A Web-Based Common Core Standards Approach (Lantham MD: Rowman & Littlefield Publishing Group, Inc., 2014). 191 pp.
ISBN 978-1-4758-1050-9 (cloth); ISBN …-1051-6 (pbk); ISBN…-1052-3 (electronic).

This book could be a breakthrough for teachers in the trenches who are interested in or need to know about quantitative literacy (QL). It is a resource providing 85 topical pieces, averaging 1.5 pages, in which a featured Web site is presented, described, and accompanied by 2-4 critical-thinking questions purposefully drawing on data from the Web site. The featured Web sites range from …

The Esther Forbes Papers, Esther Forbes

Finding Aids

The Esther Forbes Papers contain original manuscripts written by Forbes during her childhood and college years. They also contain manuscripts for The Running of the Tide, Rainbow on the Road, and Paradise. With the papers are housed bibliographic material about Esther Forbes collected by Jack Bales and published as: Esther Forbes: A Bio-Bibliography of the Author of Johnny Tremain, by The Scarecrow Press, Inc., Lanham, Md., 1998, Scarecrow Author Bibliographic Series, No. 98.

Gsu View, 2015-07-07, Office Of Marketing And Communications

GSU View

Newsletter published by Governors State University 2007-current.

A Heroic Ogre Headlines New High School Theatre Collaborative Program, Office Of Marketing And Communications

Press Releases

The Crete-Monee Enrichment Program, under the direction of Gary Thorsky, has been selected as the first high school theatre group to participate in Governors State University’s new Theatre & Performance Studies (T.A.P.S.) High School Theatre Collaborative. Students and program participants will be presenting Shrek the Musical at GSU’s Center for Performing Arts from July 24-26. The mission of the collaborative is to partner with high school theatre groups in developing, educating and inspiring young actors and technicians in their craft.

Transdisciplinarity: A Review Of Its Origins, Development, And Current Issues, Jay H. Bernstein

Publications and Research

Transdisciplinarity originated in a critique of the standard configuration of knowledge in disciplines in the curriculum, including moral and ethical concerns. Pronouncements about it were first voiced between the climax of government-supported science and higher education and the long retrenchment that began in the 1970s. Early work focused on questions of epistemology and the planning of future universities and educational programs. After a lull, transdisciplinarity re-emerged in the 1990s as an urgent issue relating to the solution of new, highly complex, global concerns, beginning with climate change and sustainability and extending into many areas concerning science, technology, social problems and …

Larry Hartpence V. Township Of Madison

2015 Decisions

USDC for the Middle District of Pennsylvania

Alterations In Activation, Cytotoxic Capacity And Trafficking Profile Of Peripheral Cd8 T Cells In Young Adult Binge Drinkers, José Luis Zaldivar Fujigaki, América Guadalupe Arroyo Valerio, Juan Carlos Lopez Alvarenga, Esperanza Gabriela Gutiérrez Reyes, David Kershenobich, Joselin Hernández Ruiz

School of Medicine Publications

Background: Excess of alcohol consumption is a public health problem and has documented effects on the immune system of humans and animals. Animal and in vitro studies suggest that alcohol abuse changes CD8 T cell (CD8) characteristics, however it remains unknown if the CD8 profile of binge drinkers is different in terms of activation, trafficking and cytotoxic capacity.

Aim: To analyze the peripheral CD8 cytotoxic capacity, activation and trafficking phenotypic profile of Mexican young adults with regard to alcohol consumption pattern.

Methods: 55 Mexican young adults were stratified as Light (20), Intermediate (18) or Binge drinkers (17) according to their …

Intracranial Catheter And Methods Of Use, Steven Bennett

USF Patents

A catheter assembly for intracranial treatment of a subject that includes an outer tube that may be connected to an infusion or osmotic pump and delivered through a bendable catheter to the target brain site of the subject. The assembly facilitates regular accurate placement of drug or compound delivery at the tissue region without additional contact and minimizes trauma to the subject.

Universal Laparoscopic Suturing Device, Stuart Hart, Sinan Onal, Susana K. Lai-Yuen

USF Patents

A laparoscopic suturing device includes a handle and a shaft mounted to the handle. A toggle knob is adapted to rotate the shaft about its longitudinal axis. A pair of opposed jaws, each having a hollow structure, open and close relative to one another. A needle carrier and a needle holder are respectively slideably disposed in a lumen of a first and a second jaw. A needle has first and second pointed ends and is adapted to be press fit into the lumen of the first jaw with the first pointed end exposed and alternatively into the lumen of the …

Um Hosts Joint Language Workshop With French Embassy, Michael Newsom

University of Mississippi News

Sessions focus on using games as learning tools

Food Sharing Among Hadza Hunter-Gatherer Children, Alyssa N. Crittenden, David A. Zes

Anthropology Faculty Research

Human prosociality is one of the defining characteristics of our species, yet the ontogeny of altruistic behavior remains poorly understood. The evolution of widespread food sharing in humans helped shape cooperation, family formation, life history, language, and the development of economies of scale. While the behavioral and ecological correlates of food sharing among adults are widely studied, very little is known about food sharing among children. Here, in the first study to analyze the food sharing patterns of hunter-gatherer children, we show that while sharing may be biased towards kin, reciprocity characterizes the majority of all sharing dyads, both related …

Bio-Fuel Alternatives In South African Airways (Saa) Operations - Is It An Effective Response To Vulnerability Over Carbon Taxes And Penalty?, Daniel Kwasi Adjekum

International Journal of Aviation, Aeronautics, and Aerospace

The paper did a comparative analysis of the carbon emission and European Union Emission Trading Surcharges (EU ETS) of South African Airways (SAA) current fleet that used aviation jet A1 fuel and the same fleet if it had used a 25% bio-fuel ‘drop in’ for the European routes within the first quarter of the 2014 flying year (FY 14). Operational data in terms of the flight scheduled, aircraft type, total time enroute, route stage length, passenger estimates were obtained through SAA’s flight operations website. An independent t–test was conducted to compare means of the emissions. The mean carbon dioxide …

A Self-Lysis Pathway That Enhances The Virulence Of A Pathogenic Bacterium, Kirsty A. Mcfarland, Emily L. Dolben, Michele Leroux, Tracy K. Kambara, Kathryn Ramsey, Robin Kirkpatrick, Joseph Mougous, Deborah Hogan, Simon Dove

Dartmouth Scholarship

In mammalian cells, programmed cell death (PCD) plays important roles in development, in the removal of damaged cells, and in fighting bacterial infections. Although widespread among multicellular organisms, there are relatively few documented instances of PCD in bacteria. Here we describe a potential PCD pathway in Pseudomonas aeruginosa that enhances the ability of the bacterium to cause disease in a lung infection model. Activation of the system can occur in a subset of cells in response to DNA damage through cleavage of an essential transcription regulator we call AlpR. Cleavage of AlpR triggers a cell lysis program through de-repression of …

Changing Spaces: Creating The Next Generation Of Work Environments For Library Staff, Sharon L. Bostick, Brian Irwin

Proceedings of the IATUL Conferences

No abstract provided.

High Quality Visual Arts Education K-8, The Student, The Principal, And The Teacher, Patricia A. Hayes

Education Dissertations

The national infrastructure of arts education shows continued rhetorical support, updated visual art standards, attributes in 21^st century learning frameworks, and research affirming arts disciplines as a core subject still valued today. Concerns from the past, however, show and continue to portend a cloudy future for visual arts education against high profile national standards and high stakes assessments focused on mathematics, language arts, and science. This study provides four views of visual arts education: (a) current research, advocacy, and national and state standards supporting sustained high-quality visual arts education (HQVAE); (b) a renewed look at the Discipline-Based Art Education …

Machine Learning Approaches For Phenotype Refinement To Improve Genetic Association Analysis, Jiangwen Sun

Doctoral Dissertations

Unlike univariate phenotypes such as human height, multivariate phenotypes such as substance use disorders, are characterized by multiple low level phenotypic features. Due to the substantial variation in the multivariate features, these phenotypes are heterogeneous. This phenotypic heterogeneity substantially limits the success in uncovering genetic factors of the phenotype. The identification of homogeneous disease subtypes can be both necessary and beneficial. Despite great progress in molecular genetics that allows the genomewide identification of common and rare variants, there is considerably less progress in the refinement of phenotypes.

The most recent and sophisticated phenotype refinement approaches perform unsupervised cluster analysis to …

Empowering Girls With Chemistry, Exercise And Physical Activity, Emily Clapham, Lori E. Ciccomascolo, Andrew J. Clapham

Kinesiology Faculty Publications

Research suggests that a girl's career interests in the areas of science, technology, engineering and mathematics (STEM) declines between grades 6 and 8. Similarly, in middle school, there is a decrease in physical activity among girls. Researchers at the University of Rhode Island (URI) conducted a chemistry-based science camp that took place over the public school spring break with the goal of increasing girls' interest in chemistry and physical activity. The camp included 42 middle school age girls in grades 6 through 8 from schools throughout Rhode Island. Interdisciplinary curricula were created to link chemistry with physical activity concepts used …

Tissue Characterization Using Optical Coherence Tomography, Mina Mahdian

Master's Theses

Optical coherence tomography (OCT) is a non-invasive imaging modality, which provides real-time near-histology resolution images. In dentistry, OCT has been used for early detection of carious lesions, malignant changes in the oral tissues and other indications. However, to the best of our knowledge there is no information regarding the ability of this imaging modality in differentiating between different types of tissues in the oral cavity. If OCT proves to be able to render information regarding the properties of tissues, it can be used to detect pathological changes at an early stage, which results in better treatment outcomes. In this study, …

Astrocytic Expansion In A Model Of Neurofibromatosis 1 (Nf1) Deficiency, Joel Rosiene

Master's Theses

Neurofibramatosis type 1 is an autosomal dominant disorder characterized by the development of both benign and malignant neoplasms of glial origin, as well as learning deficits and, less frequently, macrocephaly. Essential to the understanding of NF1 is the observation that the peripheral neoplasms (neurofibroma) which develop are composed primarily of NF1 negative glia which have undergone a loss of NF1 heterozygosity. The etiology of this loss of heterozygosity remains unclear, but a better characterization of these mutation events would provide insight into the cellular origins of the NF1 phenotype. CRISPR/Cas9 systems for genome editing have been, since 2013, a significant …

"Boys And Girls In No Man’S Land: English Canadian Children And The First World War (Book Review)" By Susan R. Fisher, Kyle Falcon

Canadian Military History

No abstract provided.

New Brunswick’S Artillery Goes To War, 1914-1915, Lee Windsor, Roger Sarty

Canadian Military History

No abstract provided.

Arigell, Shaylin Carlton

Honors Theses

In this fictional novella, a world is torn in half by a centuries-long war between the Dregmar and the Caimthu. However, the tear in the worlds wasn't as perfect as it seemed, and now a city is poking up through the ragged seams of both worlds. A city filled with neither caimthu nor dregmar, but something else entirely, something not of their world. And that's not the only thing that snuck through the cracks.

Arigell, a soldier in the caimthu army, confronts the edges of both worlds and her own past.

Bekah, a human in another world, comes face-to-face with …