Digital Commons Network^™

Could Androgens Be Relevant To Partly Explain Why Men Have Lower Life Expectancy Than Women?, C Mary Schooling

Publications and Research

No abstract provided.

Effects Of Persuasive Communication On Intention To Save Energy: Punishing And Rewarding Messages, Michell Patricia Garcia Mera

Theses

Communication can be used to persuade individuals to change their intentions. This study analyzes the use of rewarding and punishing messages for the purpose of changing intention towards energy saving. It also analyzes the use of social and individual rewards and punishments and their effects in motivating behavioral change positively towards energy saving. Results show that while reward and punishment are both effective in manipulating intention positively towards energy saving behaviors, overall there is no significant difference between the two. However, when individual reward was compared to individual punishment, individual punishment was found to be more effective than reward in …

Igf-I Induces Upregulation Of Ddr1 Collagen Receptor In Breast Cancer Cells By Suppressing Mir-199a-5p Through The Pi3k/Akt Pathway., Roberta Matà, Chiara Palladino, Maria Luisa Nicolosi, Anna Rita Lo Presti, Roberta Malaguarnera, Marco Ragusa, Daniela Sciortino, Andrea Morrione, Marcello Maggiolini, Veronica Vella, Antonino Belfiore

Kimmel Cancer Center Faculty Papers

Discoidin Domain Receptor 1 (DDR1) is a collagen receptor tyrosine-kinase that contributes to epithelial-to-mesenchymal transition and enhances cancer progression. Our previous data indicate that, in breast cancer cells, DDR1 interacts with IGF-1R and positively modulates IGF-1R expression and biological responses, suggesting that the DDR1-IGF-IR cross-talk may play an important role in cancer.In this study, we set out to evaluate whether IGF-I stimulation may affect DDR1 expression. Indeed, in breast cancer cells (MCF-7 and MDA-MB-231) IGF-I induced significant increase of DDR1 protein expression, in a time and dose dependent manner. However, we did not observe parallel changes in DDR1 mRNA. DDR1 …

Multi-Modal Outcomes From Interpersonal Need (Un)Fulfillment: The Emotional, Cognitive And Behavioral Derivatives Of Consecutive Social Contingencies, Kyle Steven Hull

Doctoral Dissertations

The current study assessed the relationship between the core dimensions of interpersonal communication and relationships, power and intimacy, on the activation of individualistic-prosocial affect systems and subsequent interpersonal outcomes. Despite extensive research examining each dimension, mixed findings are prevalent and few have investigated their potential interaction. This study addressed these issues based on current trends in interdisciplinary research. Specifically, manipulated social triumph-defeat was followed by social inclusion-exclusion to examine their combined effect on interpersonal outcomes. Results indicate that the power and intimacy manipulations were successful, however, the relationship between them was not interactive. The current findings contradict the logical expansion …

A Comparison Of Gastrointestinal Bacterial Population Between Indoor Cats And Outdoor Cats, Farhana Binti Ikmal Hisham

Honors Theses

This study used fecal samples from four indoor cats and four indoor-outdoor cats in order to identify the microbial communities in the gut of cats. This information was then used to compare the microbial phyla between both groups for any differences. Total microbial DNA was isolated from each fecal sample, and the 16S rRNA gene was sequenced using Illumina MiSeq high throughput method. The sequences were identified using the bioinformatics program mothur. The results show that indoor cats had a more diverse microbial community as compared to outdoor cats. Indoor cat samples had 26% more microbial species, and eight more …

A Sustainability Analysis Of Team Orange County’S Home Life Events During The U.S. Department Of Energy: 2015 Solar Decathlon, Lauren Sato, Alexandra Fw Sidun

Student Scholar Symposium Abstracts and Posters

This project will look at the U.S. Department of Energy’s 2015 Solar Decathlon and examine Chapman University’s involvement in Team Orange County. This project will further examine the Home Life sub-competition by studying the sustainability of the components of the two Home Life dinners, the movie night party, and the energy budget associated with each of the three events. Reviewing team documents and collecting data from affiliated team members will give us a wholesome overview of the efforts taken to achieve sustainability for the dinners and movie night. We found various practices were incorporated in the menu-concepts for the three …

Field Experiments Demonstrate That Heat Spells Can Reduce Territory Defense In The Owl Limpet, Lottia Gigantea, Nelson Gould, Tracey Gunanto, Christina Chavez, Jessica Martinez, William Wright

Student Scholar Symposium Abstracts and Posters

The intertidal zone may provide insights into how global climate change will impact natural ecosystems because its inhabitants are so vulnerable to heat stress during daytime low tides. The territorial limpet, Lottia gigantea, significantly changes the mid to high intertidal landscape by removing sessile organisms (barnacles, mussels, coralline algae), removing or redistributing gastropod grazers (snails and limpets), and encouraging the growth of micro-algae. We measured temperature and behavior to ask whether heat spells impede territorial behavior. During daytime low tides we artificially heated tagged limpets (25-35°C, vs. 15-24°C in unheated control limpets) in a shaded habitat and returned …

A Review Of The Genus Isometrus Ehrenberg, 1828 (Scorpiones: Buthidae) With Descriptions Of Four New Species From Asia And Australia, František Kovařík

Euscorpius

Four new species of the genus Isometrus are described: Isometrus (Reddyanus) bilyi from Australia, I. (R.) petrzelkai from Vietnam and Thailand, I. (R.) problematicus from India and I. (R.) khammamensis from India. Keys are presented to all species of both subgenera of Isometrus. Lectotypes are designated for I. (I.) thurstoni Pocock, 1893 and I. (R.) assamensis Oates, 1888. I. (I.) sankariensis Tikader & Bastawade, 1983 is synonymized with I. (I.) thurstoni Pocock, 1893. First time records include I. (I.) thurstoni Pocock, …

Getting It Right From The Beginning: Imagination And Education In John Dewey And Kieran Egan, Davide Weible

Education and Culture

No abstract provided.

There Are No Schools In Utopia: John Dewey’S Democratic Education, Ian T. E. Deweese-Boyd

Education and Culture

No abstract provided.

Representing Dewey’S Constructs Of Continuity And Interaction Within Classrooms, Susan J. Mayer

Education and Culture

No abstract provided.

Innovation's Renewing Potential: Seeing And Acting Mindfully Within The Fecundity Of Educative Experiences, Margaret A. Macintyre Latta, Susan Crichton

Education and Culture

No abstract provided.

In Memoriam: Philip W. Jackson, December 2, 1928–July 21, 2015, A Life Well Lived, David A. Granger, Craig A. Cunningham, David T. Hansen

Education and Culture

No abstract provided.

High-Level Systematics And Phylogeny Of The Extant Scorpions (Scorpiones: Orthosterni), Michael E. Soleglad, Victor Fet

Euscorpius

A number of authors (e. g. Birula, 1917a, 1917b; Mello-Leitão, 1945; Stockwell, 1989) addressed above-level systematics of extant scorpions, and accepted the grouping of scorpion families in several superfamilies. At the same time, Kjellesvig-Waering (1986) classified all extant scorpions under the same superfamily, Scorpionoidea. Sissom (1990) and Fet et al. (2000) did not list any superfamilies, considering the systematic situation above family (and often at the family level as well) unresolved. Most recently, Lourenço (2000a) listed six superfamilies, largely following the unpublished but important study of Stockwell (1989). The goal of this paper is to address scorpion systematics and phylogeny …

The Scorpion Sternum: Structure And Phylogeny (Scorpiones: Orthosterni), Michael E. Soleglad, Victor Fet

Euscorpius

The structure of the sternum of all major Recent scorpion groups is analyzed in detail. Based on this analysis, two fundamental sternum types are identified, described and illustrated, type 1 and type 2. These sternum types are distinguished by criteria based on external and internal structural features. The sternum types described herein are offered as a replacement for the various characterizations used throughout the last 140 years which emphasize only gross overall shape and proportions. Phylogenetic and taxonomic ramifications of these new sternal types are discussed. The Carboniferous fossil scorpion Palaeopisthacanthus schucherti Petrunkevitch is assigned to sternum type 1 …

The Motor Vehicle And Clean Air, Russell E. Maccleery

Purdue Road School

No abstract provided.

Spartan Daily, December 8, 2015, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily (School of Journalism and Mass Communications)

Volume 145, Issue 41

Design And Testing Of Novel Anthrax Vaccines Utilizing A Tobacco Mosaic Virus Expression System, Ryan C. Mccomb

KGI Theses and Dissertations

Anthrax is a potentially fatal disease caused by the bacteria Bacillus anthracis. Infection and disease occur after spores gain entry into the body, germinate into vegetative bacteria, and produce toxin. Bacillus anthracis spores have been engineered as bioweapons and have been used repeatedly in warfare and terrorism to inflict casualties in military and civilian populations. Currently, only one vaccine has been approved for prevention of anthrax in the United States. This vaccine is an undefined product that is difficult to produce, requires a long vaccination schedule, and is reactogenic. Efforts to make an improved anthrax vaccine are being pursued. …

The Cauldron, 2015, Issue 14, Elissa L. Tennant, Abraham Kurp, Abby Burton, Morgan E. Elswick

The Cauldron Archives

The Cauldron issue 14 covers Engineering students senior proposals, MSA fundraiser for Syrian refugees, students voice concerns to President Berkman, Berkman hosts annual holiday reception, November crime watch, CSU Vikings start new era at Quicken Loans Arena, Browns season over, Rule 5 Draft may hurt Tribe, Winter break checklist, must-see holiday performances, senior project collab, "A Head Full of Dreams" album review, best and brightest albums of 2015, "Victor Frankenstein" review, "Creed" review, misconceptions about Planned Parenthood, praying for Paris, disadvantages of taking the bus to class.

Egf As A New Therapeutic Target For Medulloblastoma Metastasis, Jennifer Rico-Varela, Tanya Singh, Sean Mccutcheon, Maribel Vazquez

Publications and Research

Medulloblastoma (MB) is a malignant pediatric brain tumor known for its aggressive metastatic potential. Despite the well-documented migration of MB cells to other parts of the brain and spinal column, MB chemotaxis is poorly understood. Herein, we examined the in vitro migratory and cellular responses of MB-derived cells to external signaling of Epidermal Growth Factor (EGF), hepatocyte growth factor (HGF), platelet-derived growth factor (PDGF-BB), and the stromal cellderived factors 1-alpha (SDF-1). Experiments utilized transwell assays and immunocytochemistry to identify receptor activation in MB migration, and used a microfluidic platform to examine directionality, trajectory, and gradient-dependence of motile cells. Data illustrates …

What's In A Name?, Samuel Wright

Final Projects

The project examines the customs and values associated with naming a child, as well as the conflicts that arise in doing so.

High-Activity Mutants Of Butyrylcholinesterase For Cocaine Hydrolysis And Method Of Generating The Same, Chang-Guo Zhan, Hoon Cho, Hsin-Hsiung Tai

Pharmaceutical Sciences Faculty Patents

A novel computational method and generation of mutant butyrylcholinesterase for cocaine hydrolysis is provided. The method includes molecular modeling a possible BChE mutant and conducting molecular dynamics simulations and hybrid quantum mechanical/molecular mechanical calculations thereby providing a screening method of possible BChE mutants by predicting which mutant will lead to a more stable transition state for a rate determining step. Site-directed mutagenesis, protein expression, and protein activity is conducted for mutants determined computationally as being good candidates for possible BChE mutants, i.e., ones predicted to have higher catalytic efficiency as compared with wild-type BChE. In addition, mutants A199S/A328W/Y332G, A199S/F227A/A328W/Y332G, A199S/S287G/A328W/Y332G, …

Feeding Ecology Of The Invasive Lionfish (Pterois Spp.) And Comparison With Two Native Species: Schoolmaster Lutjanus Apodus (Walbaum, 1792) And Graysby Cephalopholis Cruentata (Lacepède, 1802), Jesse J. Secord

HCNSO Student Theses and Dissertations

Predator satiation and prey-size preference were determined for locally caught lionfish, schoolmaster, and graysby, all co-occurring predatory fishes in the Florida coral reef ecosystem. Individuals were evaluated by exposing them to wild-caught killifish over a gradient of four size classes (20 mm to 60 mm, in 10 mm increments). Preference trials extended over a 2 hr time period and were filmed to determine the order in which each prey item was consumed. Satiation was evaluated by exposing the predators to an equal number of excess prey items for 24 hrs and evaluating consumed prey weight. Lionfish and schoolmaster showed a …

Faunal Composition And Distribution Of Pelagic Larval And Juvenile Flatfishes (Teleostei: Pleuronectiformes) In The Northern Gulf Of Mexico: Connectivity Between Coastal And Oceanic Epipelagic Ecosystems, Lacey Malarky

HCNSO Student Theses and Dissertations

Pleuronectiformes (flatfishes) occur throughout the global oceans, and have high ecological and commercial importance in some areas. Though much is known regarding life history, abundance, and distribution for the benthic adult stage of flatfish species, much less is known about the pelagic larval phases of flatfishes in the open ocean. Taxonomic uncertainty and limited sampling in the oceanic Gulf of Mexico contribute to data gaps with respect to the distribution of early life history stage of flatfishes in this region. Knowledge of the faunal composition, abundance and distribution of larval flatfishes, such as members of Bothus, which have extended …

Daily Eastern News: December 08, 2015, Eastern Illinois University

December

No abstract provided.

Effect Of A Dietary Intervention On Glucocorticoid-Induced Metabolic Syndrome, Leeanna Allyson Beech

Electronic Theses and Dissertations Archive

This study aimed to determine if a dietary intervention of fish oil could reduce the risk of metabolic syndrome phenotype associated with glucocorticoids (GC), given as part of the acute lymphocytic leukemia (ALL) treatment. Weaned C57BL/6 male mice were assigned either a standard rodent chow or Western-type diets containing 45% calories from fat consisting of lard (high omega-6/low omega-3 fatty acids). At six weeks of age, GC treatment was given daily for 28 days to half the mice in each diet group. Mice on the lard diet either remained on this diet or were switched to an isocaloric diet containing …

Restoring Digestive Health, Kristin M. Corbin, Dnp, Aprn, Fnp-C

Doctor of Nursing Practice (DNP) Translational and Clinical Research Projects

Purpose: The purpose of this translational research project was to outline the healthcare problems associated with Functional Gastrointestinal Disorders and to explore the effectiveness of a gastrointestinal protocol utilized at Atlanta Center for Holistic and Integrative Medicine. The goal of this protocol is to restore digestive health with probiotics, digestive enzymes, and glutamine.

Background: Functional Gastrointestinal Disorders affect one in every four adults in the United States. These disorders encompass a variety of symptoms including diarrhea, constipation, cramping, abdominal pain, flatulence, reflux, and bloating without an identified physiological cause. There is currently no cure for Functional Gastrointestinal Disorders and treatment …

Transcription Factor Runx3 Is Induced By Influenza A Virus And Double-Strand Rna And Mediates Airway Epithelial Cell Apoptosis, Huachen Gan, Qin Hao, Steven Idell, Hua Tang

School of Medicine Faculty Publications and Presentations

Influenza A virus (IAV) targets airway epithelial cells and exploits the host cell machinery to replicate, causing respiratory illness in annual epidemics and pandemics of variable severity. The high rate of antigenic drift (viral mutation) and the putative antigenic shift (reassortant strains) have raised the need to find the host cell inducible factors modulating IAV replication and its pathogenesis to develop more effective antiviral treatment. In this study, we found for the first time that transcription factor Runx3, a developmental regulator and tumor suppressor, was induced by IAV H1N1 and H3N2, viral RNA, a synthetic analog of viral double-stranded RNA …

Materials And Methods For Reduction Of Protein Tau And Treatment Of Neurodegenerative Diseases, Chad Dickey, Matthew Lebar, Bill J. Baker, Jeffrey Jones

USF Patents

The subject invention provides a myricanol compound that is in predominant form of (+)-αR,11S-myricanol as compared to (−)-αS,11R-myricanol. In one embodiment, the (+)-αR,11S-myricanol is isolated from Myrica cerifera, and is in about 86% enantiomeric excess of (−)-αS,11R-myricanol. The subject invention also pertains to therapeutic compositions and methods for treatment of neurodegenerative diseases, in particular, neurodegenerative diseases associated with abnormal accumulation of protein tau. Specifically exemplified herein is the therapeutic use of myricanol and myricanone isolated from root barks of Myrica species. Also provided are methods for preparing extracts of the subject invention from Myrica species.

Compounds Having Antiparasitic Or Anti-Infectious Activity, Michael K. Riscoe, Jane X. Kelly, Rolf W. Winter, David J. Hinrichs, Martin J. Smilkstein, Aaron Nilsen, Jeremy Burrows, Dennis Kyle, Roman Manetsch, Richard M. Cross, Andrii Monastyrskyi, David L. Flanigan

USF Patents

Compounds of formula I:

or formula II:

or a pharmaceutically acceptable salt of formula I or formula II, wherein: R1 is H, hydroxyl, alkoxy, acyl, alkyl, cycloalkyl, aryl, or heteroaryl; R2 is methyl or haloalkyl; R4 is hydroxyl, carbonyloxy, or carbonyldioxy; and R3 is aliphatic, aryl, aralkyl, or alkylaryl; and R5, R6, R7 and R8 are each individually H, halogen, alkoxy, alkyl, haloalkyl, aryl, nitro, cyano, amino, amido, acyl, carboxyl, substituted carboxyl, or —SO2R10, wherein R10 is H, alkyl, amino or haloalkyl; provided that in formula I, R5 and R7 are not both H or R6 is not H or …