Digital Commons Network^™

Monitoring The Threat Of Sinkhole Formation Under A Portion Of Us 18 In Cerro Gordo County, Iowa Using Tdr Measurements, Kevin O'Connor, Matthew Trainum

Sinkhole Conference 2015

Sinkhole formation is a common occurrence in northeast Iowa, and U.S. 18 in Cerro Gordo County was constructed over an area where sinkhole formation had only been locally known. It had not been recorded or identified in the Iowa DNR database at the time. Since 2004, sinkholes have developed along the right of way. Geophysical surveys contributed very little in the identifying the cause. However a Soil Survey (drilling program) identified numerous voids within carbonate bedrock. The soil borings indicated that shale overlying the carbonate rock has been removed/eroded, and resulted in the development of a karst subsurface through the …

Evaluation Of Veterinary Pharmaceuticals And Iodine For Use As A Groundwater Tracer In Hydrologic Investigation Of Contamination Related To Dairy Cattle Operations, Larry Boot Pierce, Honglin Shi

Sinkhole Conference 2015

Standard groundwater tracers such as Rhodamine WT, Fluorescein, Eosin and Tinopal CBX effectively provide a snapshot of hydrological conditions over a brief period of time and in a tightly controlled setting. However, in complex environmental situations with multiple potential sources, groundwater hydrologists are often seeking groundwater tracers that have extended longevity in the natural environment and the ability to directly pinpoint source locations. After reviewing operations of the nearby dairy it was determined that emerging contaminants, specifically two bovine veterinary pharmaceuticals (antibiotics), cephapirin sodium (CEPNa) and cephapirin benzathine (CEPB), and a sanitation agent, elemental Iodine (I) may have potential as …

Using Nitrate, Chloride, Sodium, And Sulfate To Calculate Groundwater Age, Kimm Crawford, Terry Lee

Sinkhole Conference 2015

Regression analysis is used to identify monotonic trends to assign water age using ion data from two large well water databases from southeast Minnesota (SE MN). Nitrate (NO3-N), chloride (Cl), sodium (Na), and sulfate (SO4) ions in the commonly used aquifers in SE MN can be used as groundwater tracers since they are either entirely or partly anthropogenic in their sources, their loading occurs on a regional scale, and they are almost entirely conserved. Ion concentrations over time are used to establish six trend patterns. Two patterns are unchanging (background and stable above background), and four are changing (linear up, …

Recharge Area Of Selected Large Springs In The Ozarks, Bill Duley, Cecil Boswell, Jerry Prewett

Sinkhole Conference 2015

Ongoing work by the Missouri Geological Survey (MGS) is refining the known recharge areas of a number of major springs in the Ozarks. Among the springs being investigated are: Mammoth Spring (Fulton County, Arkansas), and the following Missouri springs: Greer Spring (Oregon County), Blue Spring (Ozark County), Blue/Morgan Spring Complex (Oregon County), Boze Mill Spring (Oregon County), two different Big Springs (Carter and Douglas County) and Rainbow/North Fork/Hodgson Mill Spring Complex (Ozark County). Previously unpublished findings of the MGS and United States Geological Survey (USGS) are also being used to better define recharge areas of Greer Spring, Big Spring (Carter …

Earthonomics: Balancing Between Earth And Business, Yazen Abdin

Environmental and Earth Law Journal (EELJ)

Economists consistently fail to account that Earth has a finite amount of resources. This article analyzes the behavior of corporate America and the effect it has on the world form an Earth jurisprudence standpoint. It will explore twp specific industries, oil and food, and what role they have played in the environment's health. It also explores potential solutions.

Barriers To Neighborhood Wildlife Habitats: Is Lawn Uniformity Worth Biodiversity Loss?, Sonya Cunningham

Environmental and Earth Law Journal (EELJ)

Local ordinances and covenants, conditions or restrictions (CCRs) usually create barriers to wildlife habitats in neighborhoods. Fortunately, it is possible under limited circumstances for a homeowner to have a wildlife habitat in their lawn. This comment will provide and overview of those limited circumstances, as well as provide steps to challenge the enforcement of ordinances and CCRs. In addition, this define and examine the concept of biodiversity and biodiversity loss.

Yappari, As I Thought: Listener Talk In Japanese Communication, Haru Yamada

Global Advances in Business Communication

Listener Talk, typical of Japanese communication, places the listener at the center of interaction. Listener Talk differs from many western styles of communication where the onus of the explicit form of communication Victor (1992) calls the Direct Plan is on the speaker. Listener Talk finds its roots in the others-centered focus of Buddhist and Taoist traditions and the values the communicators place on silence and implicit talk.

Drawing on data from both intracultural and cross-cultural bank meetings, I bring to fore a strategy I examined in my book, Different Games, Different Rules (1997), and two additional strategies for Listener Talk …

Optimizing Production Of Fc-Amidated Peptides By Chinese Hamster Ovary Cells, Kristina Carlson, Richard E. Mains, Betty A. Eipper

UCHC Articles - Research

Background

Amidation of the carboxyl terminal of many peptides is essential for full biological potency, often increasing receptor binding and stability. The single enzyme responsible for this reaction is peptidylglycine α-amidating monooxygenase (PAM: EC 1.14.17.3), a copper- and ascorbate-dependent Type I membrane protein.

Methods

To make large amounts of high molecular weight amidated product, Chinese hamster ovary (CHO) cells were engineered to express exogenous PAM. To vary access of the enzyme to its substrate, exogenous PAM was targeted to the endoplasmic reticulum, trans-Golgi network, endosomes and lysosomes or to the lumen of the secretory pathway.

Results

PAM was equally …

Machinal, Jennifer Popple

2010-2019: All Shows

The play's title means "automatic" or "mechanical" in French and is based loosely on the murder trial of Ruth Snyder and her lover, Judd Gray, who together murdered Snyder's husband. Convicted of murdering her husband, Snyder later received the electric chair. A woman's role during this era in history is confined and regimented to wife, mother, housekeeper, and sexual partner. Love is considered unnecessary, and thus many women are trapped in their dependent status, living a hellish life in a loveless marriage. The relationship between Helen Jones and her husband, George H. Jones, is no different. However, when a man …

The Impact Of Dose On Naming Accuracy With Persons With Aphasia, Catherine A. Off, Kristie A. Spencer, Margaret Rogers

Speech, Language, Hearing, and Occupational Sciences Faculty Publications

Background: Although aphasia rehabilitation has been shown to be efficacious, many questions remain regarding how best to deliver treatment to maximise functional gains for persons with aphasia. Treatment-delivery variables, such as intensity and dosage, are likely to influence both behavioural and structural changes during anomia treatment. While numerous protocols have concluded that treatment intensity positively impacts functional outcomes, few studies to date have examined the role that dose plays in patient outcomes for anomia treatment. Aims: This study sought to investigate how manipulating dose of repeated confrontation naming within sessions influences naming in persons with aphasia. Repeated practice of confrontation …

Cellular Hokey Pokey: A Coarse-Grained Model Of Lamellipodia Protrusion Dynamics Driven By Fluctuations In Actin Polymerization, Gillian Ryan, Dimitrios Vavylonis, Naoki Watanabe

Physics Publications

Animal cells that spread onto a surface often rely on actin-rich cell extensions called lamellipodia to execute cell protrusion. XTC cells on a two-dimensional substrate exhibit regular protrusion and retraction of their lamellipodium, even though the cell is not translating. Travelling waves of protrusion have also been observed, similar to those observed in crawling cells. These periodic fluctuations in leading edge position have been linked to excitable actin dynamics near the cell edge using a one dimensional model of actin dynamics, as a function of arc-length along the cell. In this work we extend this earlier model of actin dynamics …

Laterality Enhances Numerical Skills In The Guppy, Poecilia Reticulata, Marco Dadda, Christian Agrillo, Angelo Bisazza, Culum Brown

Sentience Collection

It has been hypothesized that cerebral lateralization can significantly enhance cognition and that this was one of the primary selective forces shaping its wide-spread evolution amongst vertebrate taxa. Here, we tested this hypothesis by examining the link between cerebral lateralization and numerical discrimination. Guppies, Poecilia reticulata, were sorted into left, right and non-lateralized groups using a standard mirror test and their numerical discrimination abilities tested in both natural shoal choice and abstract contexts. Our results show that strongly lateralized guppies have enhanced numerical abilities compared to non-lateralized guppies irrespective of context. These data provide further credence to the notion that …

Pnaktide Inhibits Na/K-Atpase Reactive Oxygen Species Amplification And Attenuates Adipogenesis, Komal Sodhi, Kyle Maxwell, Yanling Yan, Jiang Liu, Muhammad Chaudhry, Morgan Getty, Zijian Xie, Nader G. Abraham, Joseph I. Shapiro Md

Biochemistry and Microbiology

Obesity has become a worldwide epidemic and is a major risk factor for metabolic syndrome. Oxidative stress is known to play a role in the generation and maintenance of an obesity phenotype in both isolated adipocytes and intact animals. Because we had identified that the Na/K-ATPase can amplify oxidant signaling, we speculated that a peptide designed to inhibit this pathway, pNaKtide, might ameliorate an obesity phenotype. To test this hypothesis, we first performed studies in isolated murine preadipocytes (3T3L1 cells) and found that pNaKtide attenuated oxidant stress and lipid accumulation in a dose-dependent manner. Complementary experiments in C57Bl6 mice fed …

Autophagy Protects Against Cyp2e1/Chronic Ethanol-Induced Hepatotoxicity, Yongke Lu, Arthur I. Cederbaum

Pharmacology, Physiology and Toxicology

Autophagy is an intracellular pathway by which lysosomes degrade and recycle long-lived proteins and cellular organelles. The effects of ethanol on autophagy are complex but recent studies have shown that autophagy serves a protective function against ethanol-induced liver injury. Autophagy was found to also be protective against CYP2E1-dependent toxicity in vitro in HepG2 cells which express CYP2E1 and in vivo in an acute alcohol/CYPE1-dependent liver injury model. The goal of the current report was to extend the previous in vitro and acute in vivo experiments to a chronic ethanol model to evaluate whether autophagy is also protective against CYP2E1-dependent liver …

In Re: Forever Green Athletic

2015 Decisions

USDC for the Eastern District of Pennsylvania

Framing The Mh17 Disaster – More Heat Than Light?, Simon A. Bennett

International Journal of Aviation, Aeronautics, and Aerospace

Despite the reductionist analyses produced by politicians and the Fourth Estate, the loss of Malaysia Airlines Flight MH17 was a systems accident – a product of the interactions between the actants that compose the commercial aviation system network-space. As an antidote to reductionism’s ‘fundamental attribution error’, this paper presents a systems-thinking-informed analysis of the MH17 disaster. To this end it draws on Actor-Network Theory and the work of Reason, Toft, Dekker, Hollnagel and other systems-thinking advocates. Whether intentional or not, politicians’ reductionist analyses generated political capital. European Union and American finger-pointing distracted from aviation authorities’ and airlines’ ill-advised routing policies. …

October 16, 2015, The Dakota Student

The Dakota Student

No abstract provided.

Genestation 1.0: A Synthetic Resource Of Diverse Evolutionary And Functional Genomic Data For Studying The Evolution Of Pregnancy-Associated Tissues And Phenotypes, Mara Kim, Brian A. Cooper, Rohit Venkat, Julie B. Phillips, Haley R. Eidem, Jibril Hirbo, Sashank Nutakki, Scott M. Williams, Louis J. Muglia, J. Anthony Capra, Kenneth Petren, Patrick Abbot, Antonis Rokas, Kriston L. Mcgary

Dartmouth Scholarship

Mammalian gestation and pregnancy are fast evolving processes that involve the interaction of the fetal, maternal and paternal genomes. Version 1.0 of the GEneSTATION database (http://genestation.org) integrates diverse types of omics data across mammals to advance understanding of the genetic basis of gestation and pregnancy-associated phenotypes and to accelerate the translation of discoveries from model organisms to humans. GEneSTATION is built using tools from the Generic Model Organism Database project, including the biology-aware database CHADO, new tools for rapid data integration, and algorithms that streamline synthesis and user access. GEneSTATION contains curated life history information on pregnancy and …

Naturally Occurring Deletion Mutants Of The Pig-Specific, Intestinal Crypt Epithelial Cell Protein Clca4b Without Apparent Phenotype., Stephanie Plog, Nikolai Klymiuk, Stefanie Binder, Matthew J. Van Hook, Wallace B. Thoreson, Achim D. Gruber, Lars Mundhenk

Journal Articles: Ophthalmology

The human CLCA4 (chloride channel regulator, calcium-activated) modulates the intestinal phenotype of cystic fibrosis (CF) patients via an as yet unknown pathway. With the generation of new porcine CF models, species-specific differences between human modifiers of CF and their porcine orthologs are considered critical for the translation of experimental data. Specifically, the porcine ortholog to the human CF modulator gene CLCA4 has recently been shown to be duplicated into two separate genes, CLCA4a and CLCA4b. Here, we characterize the duplication product, CLCA4b, in terms of its genomic structure, tissue and cellular expression patterns as well as its in vitro electrophysiological …

Designing A Mobile Application To Support The Indicated Prevention And Early Intervention Of Childhood Anxiety, Mandar Patwardhan, Ashish Amresh, Ryan Stoll, Kevin A. Gary, Derek B. Hamel, Armando Pina

Publications

This paper presents the design of an mHealth application for prevention and early intervention of childhood anxiety. The application is based on REACH, a preventative-early intervention protocol for childhood anxiety. This paper describes the multidisciplinary design process, sharing lessons learned in developing an effective mHealth application. This mHealth application is unique due to participant age, preventive-early intervention focus, and utilization of mobile technology in a situated manner. A design process inspired by user-centered leveraging key informant interviews was used to identify application features, including game based strategies and an animated motivational avatar. Validation was performed through external review and a …

Delegating Tax, James R. Hines Jr., Kyle D. Logue

Michigan Law Review

Congress delegates extensive and growing lawmaking authority to federal administrative agencies in areas other than taxation, but tightly limits the scope of Internal Revenue Service (IRS) and Treasury regulatory discretion in the tax area, specifically not permitting these agencies to select or adjust tax rates. This Article questions why tax policy does and should differ from other policy areas in this respect, noting some of the potential policy benefits of delegation. Greater delegation of tax lawmaking authority would allow administrative agencies to apply their expertise to fiscal policy and afford timely adjustment to changing economic circumstances. Furthermore, delegation of the …

Standing In The Way Of The Ftaia: Exceptional Applications Of Illinois Brick, Jennifer Fischell

Michigan Law Review

In 1982, Congress enacted the Foreign Antitrust Trade Improvements Act (FTAIA) to resolve uncertainties about the international reach and effect of U.S. antitrust laws. Unfortunately, the FTAIA has provided more questions than answers. It has been ten years since the Supreme Court most recently interpreted the FTAIA, and crucial questions and circuit splits abound. One of these questions is how to understand the convergence of the direct purchaser rule (frequently referred to as the Illinois Brick doctrine) and the FTAIA. Under the direct purchaser rule, only those who purchase directly from antitrust violators are typically permitted to sue under section …

Burkholderia Pseudomallei Capsular Polysaccharide Recognition By A Monoclonal Antibody Reveals Key Details Toward A Biodefense Vaccine And Diagnostics Against Melioidosis, Roberta Marchetti, Michael J. Dillon, Mary N. Burtnick, Mark A. Hubbard, Marielle Tamigney Kenfack, Yves Blériot, Charles Gauthier, Paul J. Brett, David P. Aucoin, Rosa Lanzetta, Alba Silipo, Antonio Molinaro

Peninsula Medical School

No abstract provided.

Dissecting Electronic Arts' Spore: An Analysis Of The Illicit Transfer Of Copyright Ownership Of User-Generated Content In Computer Software, Andrew P. Connors

Liberty University Law Review

No abstract provided.

Exploring Foodie Segmentation, Carol S. Kline, Jerusha Greenwood, Leah Joyner

Journal of Tourism Insights

Previous research studies have explored the activities, motivations, and outcomes for the culinary tourist, and researchers have theorized certain segments of culinary travelers (Boniface, 2003; Mitchell, Hall & McIntosh, 2000). Contrasting to this, investigation into “the foodie” and his or her activities at home has been strikingly infrequent. Exploring the foodie ‘at home’ or the foodie’s everyday behavior is critical to understanding different types of foodies, how to market to foodies, and their decision-making processes for culinary travel. The purpose of this study is to test, via an online survey, a scale that distinguishes between different types of foodies, and …

Guide To The Dr. Jane Claire Dirks-Edmunds Papers, Linfield College Archives

Linfield Archives Finding Aids

This collection reflects the life work of Dr. Jane Claire Dirks-Edmunds, a student and professor of Linfield College. A dedicated and scrupulous woman, the majority of the collection consists of her research, teaching materials, and correspondence. The collection also includes research and correspondence by Dr. Jane Claire Dirks-Edmunds’s mentor, Dr. James A. Macnab.

Chanticleer | October 15, 2015, Jacksonville State University

Chanticleer

No abstract provided.

On Rage, Shame, "Realness," And Accountability To Survivors, Kathleen Ann Livingston

Harlot: A Revealing Look at the Arts of Persuasion

This essay examines the rhetorical moves made on all sides of the recent conversation on trigger warnings. Calling for accountability to survivors, it positions trigger warnings as one practice of consent. Though in practice trigger warnings bring up issues of censorship, they can be understood as a way for survivors to take their power back by telling a bit of their trauma narrative and requesting accommodations and accountability. Unpacking the histories and the language of trigger warnings reveals how our culture thinks of survivors and how far anti-violence movements have to go.

Ay 15-16 Meeting 2015-10-15, Faculty Senate

Faculty Senate Minutes

No abstract provided.

Emoji, Emoji, What For Art Thou?, Lisa Lebduska

Harlot: A Revealing Look at the Arts of Persuasion

This essay provides a history and context for emoji as a way of re-materializing composing while simultaneously arguing that emoji do not threaten alphabetic literacy and instead provide a means of creative graphic expression. The essay acknowledges that n some instances emoji do help to clarify the intent or tone of alphabetic writing, but it notes that emoji, like alphabetic writing, is culturally and contextually bound. Emoji expand expression and doing so open themselves to re-appropriation, intepretation and even misinterpretation, along with the affirming possibilities of artistic creation.