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2015

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Utah’S Role In Protecting The Mormon Trail During The Civil War, Kenneth L. Alford Ph.D. Jan 2015

Utah’S Role In Protecting The Mormon Trail During The Civil War, Kenneth L. Alford Ph.D.

Faculty Publications

This chapter (from the 2015 book “Far Away in the West: Reflections on the Mormon Pioneer Trail” published by the Brigham Young University Religious Studies Center) sets the stage for Utah Territory’s role protecting the Mormon Trail during the Civil War by outlining the Utah War (1857-1858). This essay begins by comparing and contracting Washington, DC’s wartime interest in the trail with that of The Church of Jesus Christ of Latter-day Saints and Utah Territory. The essay then outlines the changing parties who were responsible for the trail between 1861 and 1865 – the U.S. Army (spring-summer 1861), no one …


Sacred Violence: When Ancient Egyptian Punishment Was Dressed In Ritual Trappings, Kerry Muhlestein Jan 2015

Sacred Violence: When Ancient Egyptian Punishment Was Dressed In Ritual Trappings, Kerry Muhlestein

Faculty Publications

Despite gaping holes in our knowledge of ancient Egyptian laws and punishments, the sheer amount of data available for that long-lasting culture dictates that we limit our study of punishments both topically and temporally. This article will investigate the topic of ritual-associated killing from the Old Kingdom through the Libyan era. Earlier phases of Egyptian history yield evidence of ritual killing, such as the retainer burials associated with Early Dynastic kings or the labels of Aha and Djer (fig. 1), that seem to depict ritual slaughter. Whatever the nature of these seeming programs of ritual slaying, we cannot trace a …


Making Strategic Human Capital Relevant: A Time-Sensitive Opportunity, David Kryscynski, Dave Ulrich Jan 2015

Making Strategic Human Capital Relevant: A Time-Sensitive Opportunity, David Kryscynski, Dave Ulrich

Faculty Publications

The domain of strategic human capital is emerging at the intersection of strategy and strategic human resource management. Because it is still in the development phase, its core underlying assumptions have not yet solidified. This presents a unique and time-sensitive opportunity to explore and challenge these core assumptions and, specifically, to evaluate whether these assumptions mesh with the lived experiences of practicing managers. We argue that now is the time for the field to ground itself in practical phenomena so that its insights moving forward can be both academically rigorous and practically relevant. In this paper we illustrate the problems …


Co-Location, Co-Location, Co-Location: Land Use And Housing Priorities Reimagined, Lee Anne Fennell Jan 2015

Co-Location, Co-Location, Co-Location: Land Use And Housing Priorities Reimagined, Lee Anne Fennell

Public Law and Legal Theory Working Papers

No abstract provided.


Bioethanol: Feedstock Alternatives, Pretreatments,Lignin Chemistry, And The Potential For Green Value-Added Lignin Co-Products, Ruben Michael Ceballos, N. A. Batchenkova, M.K. Y. Chan, A. X. Duffing-Romero, A. E. Nelson, S. Man Jan 2015

Bioethanol: Feedstock Alternatives, Pretreatments,Lignin Chemistry, And The Potential For Green Value-Added Lignin Co-Products, Ruben Michael Ceballos, N. A. Batchenkova, M.K. Y. Chan, A. X. Duffing-Romero, A. E. Nelson, S. Man

Biological Sciences Faculty Publications and Presentations

Major challenges still exist in the cost-competitive production of cellulosic ethanol. Lignocellulose deconstruction using physiochemical pretreatments continues to be the most efficient way to remove lignin and expose cellulose for enzyme-mediated sugar reduction. Recent interest in the development of “value-added” lignin co-products and the desire to reduce the use of hazardous materials has prompted a resurgence of interest in alternative lignocellulosic feedstock and research into environment-friendly biological pretreatments. This article provides an overview of bioethanol processes and economics, standard and alternative feedstocks, physiochemical and biological pretreatments, and lignin chemistry. The chemistry and mode of action of ligninolytic and cellulolytic enzymes …


Role Of 5'Tg3'-Interacting Factors (Tgifs) In Vorinostat (Hdac Inhibitor)-Mediated Corneal Fibrosis Inhibition, Ajay Sharma, Nishant R. Sinha, Saad Siddiqui, Rajiv R. Mohan Jan 2015

Role Of 5'Tg3'-Interacting Factors (Tgifs) In Vorinostat (Hdac Inhibitor)-Mediated Corneal Fibrosis Inhibition, Ajay Sharma, Nishant R. Sinha, Saad Siddiqui, Rajiv R. Mohan

Pharmacy Faculty Articles and Research

Purpose: We have previously reported that vorinostat, an FDA-approved, clinically used histone deacetylase (HDAC) inhibitor, attenuates corneal fibrosis in vivo in rabbits by blocking transforming growth factor β (TGFβ). The 5′TG3′-interacting factors (TGIFs) are transcriptional repressors of TGFβ1 signaling via the Smad pathway. The present study was designed to explore the expression of TGIFs in human corneal fibroblasts and to investigate their role in mediating the antifibrotic effect of vorinostat.

Methods: Human corneal fibroblast cultures were generated from donor corneas. RNA isolation, cDNA preparation, and PCR were performed to detect the presence of TGIF1 and TGIF2 transcripts. The cultures were …