Digital Commons Network^™

It Came Across The Plains: The 1918 Influenza Pandemic In Rural Nebraska, Kristin Watkins

Theses & Dissertations

The purpose of this historical case study was to understand and describe rural community experiences during the 1918 influenza pandemic in Nebraska.

Examining the rural experience in Nebraska during the 1918 influenza pandemic provided a new level of insight into the differences and similarities between the urban and rural experience. As related by a detailed study of Omaha during the 1918 pandemic, the community was devastated by disease. Despite public ordinances and health department warnings, streetcars ran at capacity, parades were held to raise money for war bonds, and the annual Aksarben Coronation took place. Cases of flu were too …

Compensatory Mechanisms And T Cell Migration In Mouse Models Of Dopaminergic Loss, Kristi M. Anderson

Theses & Dissertations

Parkinson’s disease (PD) is the most common neurodegenerative movement disorder and second most common neurodegenerative disorder. PD is characterized by the selective loss of dopaminergic neurons and dopamine neurotransmitter within the substantia nigra and termini in the striatum. Progressive loss of dopaminergic neurons occurs over many years in PD, and by the time movement disorder symptoms manifest, up to 50-70% of dopaminergic neurons have been lost. Several aspects of PD pathology have been described in detail, but a better understanding of PD progression is needed to develop more efficient treatments.

Motor symptoms associated with PD do not manifest until significant …

Development Of Manganese-Enhanced Magnetic Resonance Imaging (Memri) Methods To Study Pathophysiology Underlying Neurodegenerative Diseases In Murine Models, Aditya N. Bade

Theses & Dissertations

Manganese-enhanced magnetic resonance imaging (MEMRI) opens the great opportunity to study complex paradigms of central nervous system (CNS) in freely behaving animals and reveals new pathophysiological information that might be otherwise difficult to gain. Due to advantageous chemical and biological properties of manganese (Mn²⁺), MEMRI has been successfully applied in the studies of several neurological diseases using translational animal models to assess comprehensive information about neuronal activity, morphology, neuronal tracts, and rate of axonal transport. Although previous studies highlight the potential of MEMRI for brain imaging, the limitations concerning the use of Mn²⁺ in living animals and …

Velocirapture, Katheryn Warzak

LSU New Orleans Theses and Dissertations

N/A

A Novel Transcription Factor In Arabidopsis Thaliana Abiotic Stress Response, Achira S. Weerathunga Arachchilage

LSU New Orleans Theses and Dissertations

Plants respond to environmental stress by altering their gene expression. Under stress conditions some genes are activated and some genes are repressed. Even though a lot of work has been done to understand mechanisms of gene activation under abiotic stress very little information is available on how stress responsive genes are kept repressed under normal growth conditions. Recent work has revealed that plants use transcriptional repression as common mechanism of gene repression. Transcriptional repression is achieved by recruitment co-repressor complexes to the target genes. Recent studies have revealed that the co-repressor LUH complexes with SLK1 and SLK2 to silence Arabidopsis …

Verve, Stephanie L. Zahareas

LSU New Orleans Theses and Dissertations

No abstract provided.

Photooxidation Reactions Of Small-Chain Methyl Esters, Aerosol Photoelectron Spectroscopy, And The Photodissociation Of Ethylenediamine, Giel Muller

Master's Theses

Research conducted at the University of San Francisco is presented within this masters thesis, including the Cl-initiated photooxidation reactions of methyl propanoate, methyl butanoate, and methyl valerate (pentanoate), the aerosol photoelectron spectroscopy of isoprene and gamma-valerolactone, and the TPEPICO investigation of ethylenediamine. Experiments were conducted at the Lawrence Berkeley National Lab Advanced Light Source (ALS), the National Synchrotron Radiation Research Center in Hsinchu City (NSRRC), and the University of Stockton in California, respectively.

Queering The Wac: The World War Ii Military Experience Of Queer Women, Catherine S. Cauley

LSU New Orleans Theses and Dissertations

The demands of WWII mobilization led to the creation of the first standing women's army in the US known as the Women's Army Corps (WAC). An unintended consequence of this was that the WAC provided queer women with an environment with which to explore their gender and sexuality while also giving them the cover of respectability and service that protected them from harsh societal repercussions. They could eschew family for their military careers. They could wear masculine clothing, exhibit a masculine demeanor, and engage in a homosocial environment without being seen as subversive to the American way of life. Quite …

Positive Parenting, Conduct Problems, And Callous-Unemotional Traits, Julia E. Clark

LSU New Orleans Theses and Dissertations

The current study tested the association of both positive and negative aspects of parenting with callous-unemotional (CU) traits and conduct problems. Caregivers of 92 kindergarteners were recruited to complete a series of survey measures. Overall, parent-report of negative parenting practices was not associated with teacher report of conduct problems. However, parent report of positive parenting practices (i.e., warmth, positive reinforcement, positive communication and cooperation) was negatively associated with conduct problems and CU traits. Interactions between positive parenting variables and CU traits in their association with conduct problems indicated that positive reinforcement related more strongly to lower levels of conduct problem …

Field Study Of Electrochemical Disinfection Of Municipal Wastewater, Luis De Grau Vidal

LSU New Orleans Theses and Dissertations

Research on electrochemical disinfection of municipal wastewater has been conducted at the University of New Orleans using a continuous flow electrochemical reactor connected to a direct current (DC) power supply changing its polarity and varying the electrode distance. Bacterial inactivation and chlorine production were the main parameters that were recorded.

After months of research, it was determined that the electrochemical disinfection reactor is efficient and has a great potential for the future. There is no need to use chlorine and it has low operation costs.

The following design recommendations for an electrochemical disinfection unit were given:

• A detention time of …

Cognitive Castles: Place And The Castle Of Otranto, Kevin I. Flotte

LSU New Orleans Theses and Dissertations

This article analyzes The Castle of Otranto from a biocultural perspective. Firstly, the theoretical landscape of Gothic horror is explored. This is followed by some suggestions on how evolutionary approaches might add to the conversation about Gothic horror. The last section applies evolutionary and cognitive approaches to The Castle of Otranto in a reading of the novel. Attention is paid to the varied ways in which Gothic horror subverts and undermines evolved strategies for the creation of meaning and understanding. Gothic tropes such as the Gothic tunnel or labyrinth undercut the dynamic and ongoing creation of place that is essential …

Fearful Temperament Moderates The Association Between Positive Parenting And Children's Social Competence During Early Childhood, Jessica M. Grande

LSU New Orleans Theses and Dissertations

Social competence during kindergarten has been linked to adaptive teacher-child and peer relationships. The quality of parents’ interaction with their children during the toddler years may promote better social development placing children on a trajectory towards social competence. Quite possibly, children vary in how responsive they are to parenting efforts. This study evaluated the extent to which positive parenting predicted change in social competence from child age 3 to 4 among 137 parent-child dyads. Observational measures of positive parenting and fearful temperament were analyzed when children were 3-years of age. Teacher reports of social competence in the classroom were collected …

Arsenic, Cadmium, Copper, And Zinc Levels In Crayfish From Southwest Louisiana And Atchafalaya Basin, E. Gerald Hebert

LSU New Orleans Theses and Dissertations

Heavy metal contamination in food is a worldwide concern. Man-made ponds are domestic sites in the production of Procambarus clarkii and Procambarus zonangulus, two edible species of crayfish. Ponds may be constructed in former sugar cane or rice fields. Crayfish farming is an ancillary seasonal business within the rice-growing season. The use of products to control insects, pests, and weeds in rice and sugar cane production, may cause an accumulation of heavy metals in the crayfish tail within pond structures. Arsenic, cadmium, copper, and zinc are heavy metals that are absorbed through the roots of and distributed through rice products. …

Fathers And Sons: A Journey In Creating A Personal Work Of Cinematic Art, Samuel D. Hopson

LSU New Orleans Theses and Dissertations

This document gives an account of my artistic efforts in creating my thesis film Fathers and Sons. This document includes sections that cover the writing, casting, production design, principal photography, and editing of my film. I give special attention to the writing process in Chapter 2, because of its personal significance to my growth as a filmmaker. This chapter details the evolution of my original story concept from a drama to a comedy. The ultimate goal of my film was to create a personal work of art. This document self-reflects on how well I was able to achieve this goal, …

A Bedlam Of Shenanigans, Andrew F. Kooy

LSU New Orleans Theses and Dissertations

No abstract provided.

How The Manipulation Of The Ras Homolog Enriched In Striatum Alters The Behavioral And Molecular Progression Of Huntington’S Disease, Franklin A. Lee

LSU New Orleans Theses and Dissertations

Huntington’s disease is an incurable, progressive neurological disorder characterized by loss of motor control, psychiatric dysfunction, and eventual dystonia leading to death. Despite the fact that this disorder is caused by a mutation in one single gene, there is no cure. The mutant Huntingtin (mHtt) protein is expressed ubiquitously throughout the brain but frank cell death is limited to the striatum. Recent work has suggested that Rhes, Ras homolog enriched in striatum, which is selectively expressed in the striatum, may play a role in Huntington’s disease neuropathology. In vitro studies have shown Rhes to be an E3 ligase for the …

Headshot, Jason S. Obrien

LSU New Orleans Theses and Dissertations

n/a

Emotional And Autonomic Responding To Auditory Stimuli, Jeremy C. Peres

LSU New Orleans Theses and Dissertations

Much of the research examining emotion induction, regulation, and suppression considers solely the visual modality (e.g., pictures of faces) for emotion elicitation. In reality, emotions are cued, expressed, and interpreted through multiple modalities by employing the extensive use of auditory stimuli in addition to visual stimuli. There have been some recent efforts to offset this imbalance in modality preference by using emotional auditory stimuli alone or in addition to visual stimuli. This project aims to further investigate emotional and autonomic responding to auditory stimuli with the added component of examining differential responding across social (nonlinguistic vocal expression) and non-social auditory …

Interaction Between Angiotensin Ii And Bdnf In Modulating Sympathetic Nerve Activity, Bryan K. Becker

Theses & Dissertations

Over activation of the sympathetic nervous system is prevalent in many forms of cardiovascular disease such as chronic heart failure (CHF) and hypertension. Although increased neuronal renin-angiotensin system activity in presympathetic neurons has been well implicated in mediating this sympatho-excitation, many of the neuronal effects of angiotensin II (Ang II) signaling remain poorly understood. One particular mechanism of Ang II-mediated increases in presympathetic neuronal activity is through reductions in voltage-gated K⁺ currents. Another pathway that has profound effects on neuronal K⁺ currents and that has been previously implicated in Ang II-signaling is brain-derived neurotrophic factor (BDNF) activity through …

Atypical Protein Kinase C Dependent Polarized Cell Division Is Required For Myocardial Trabeculation, Derek L. Passer

Theses & Dissertations

A hallmark of cardiac development is the formation of myocardial trabeculations exclusively from the luminal surface of the primitive heart tube. Although a number of genetic defects in the endocardium (Grego-Bessa et al., 2007; Liu et al., 2010) and cardiac jelly (Camenisch et al., 2000) disrupt myocardial trabeculation, the role of cell polarity machinery in driving this process remains unclear. Herein, we demonstrate that atypical protein kinase C iota (Prkci) and its interacting partners of Par polarity complex are localized to the luminal side of luminal myocardial cells. Remarkably, a subset of these cells undergoes polarized cell division with the …

Biodegradable Hybrid Nanogels For Combination Chemotherapy, Swapnil Desale

Theses & Dissertations

Combination chemotherapy is commonly used to treat cancer, because such a therapy regimens usually involve sequential administration of multiple drugs and allow targeting different cell signaling pathway. The co-delivery of drug combination at a controlled ratio via the same vehicle is offering the advantages such as spatial-temporal synchronization of drug exposure, synergistic therapeutic effects and suppression of drug resistance. Undoubtedly, there are several molecular and pharmacological factors that determine the effectiveness of drug combinations. A rationally designed drug combination is required since certain drug ratios and the definitive exposure to the targets of interest can only be synergistic while others …

The Role Of Cxcr2 In Pancreatic Cancer Development And Progression, Abhilasha Purohit

Theses & Dissertations

This dissertation examines the role of CXCR2, a seven transmembrane G- protein coupled receptor, in mediating autocrine as well as paracrine mechanisms during pancreatic cancer progression. Data presented in the initial section demonstrates the aberrant expression of the CXCR2 biological axis in human pancreatic cancer tissue specimens. A study performed within the first section of this dissertation investigates the contribution of CXCR2 signaling in pancreatic cancer initiation. These studies have identified a novel role of CXCR2 in mediating KRAS^(G12D) -induced autocrine growth transformation of pancreatic cancer cells. The upregulation of the CXCR2 biological axis was found to be directly …

Developing And Testing An Anguilliform Robot Swimming With Theoretically High Hydrodynamic Efficiency, John B. Potts Iii

LSU New Orleans Theses and Dissertations

An anguilliform swimming robot replicating an idealized motion is a complex marine vehicle necessitating both a theoretical and experimental analysis to completely understand its propulsion characteristics. The ideal anguilliform motion within is theorized to produce ``wakeless'' swimming (Vorus, 2011), a reactive swimming technique that produces thrust by accelerations of the added mass in the vicinity of the body. The net circulation for the unsteady motion is theorized to be eliminated.

The robot was designed to replicate the desired, theoretical motion by applying control theory methods. Independent joint control was used due to hardware limitations. The fluid velocity vectors in the …

Response Of Fishes To Restoration Projects In Bayou St. John Located Within The City Of New Orleans, Louisiana, Including Hydrological Characterization And Hydrodynamic Modelling, Patrick W. Smith

LSU New Orleans Theses and Dissertations

Quantifying the impacts of restoration on coastal waterways is crucial to understanding their effectiveness. Here, I look at the impacts of multiple restoration projects on urban waterways within the city limits of New Orleans, LA, with an emphasis on the response of fishes. First I report the effects of two projects designed to improve exchange down estuary on the hydrologic characteristics of Bayou St. John (BSJ). Within BSJ, flow is dominated by subtidal wind driven processes. Removal of an outdated flood control structure did not appear to alter exchange in BSJ, but removal combined with sector gate openings did. I …

"It's No Life Being A Steer": Violence, Masculinity, And Gender Performance In The Sun Also Rises And In Our Time, Brock J. Thibodaux

LSU New Orleans Theses and Dissertations

Nearly all discussions of Hemingway and his work touch on the theme of masculinity, a recurrent theme in all of his works. Examinations of Hemingway and his relationship to masculinity have almost unanimously treated the author as a misogynist and a champion of violent masculinity. However, since the posthumous publication of The Garden of Eden in 1986, there has been much discussion of Hemingway’s uncharacteristic use of androgynous characters in the novel. Critics have taken this as a clue that Hemingway possessed a complex attitude regarding gender fluidity, but have failed to examine the constructions of gender and identity in …

Electromechanics Of An Ocean Current Turbine, Vasileios Tzelepis

LSU New Orleans Theses and Dissertations

The development of a numeric simulation for predicting the performance of an Ocean Current Energy Conversion System is presented in this thesis along with a control system development using a PID controller for the achievement of specified rotational velocity set-points. In the beginning, this numeric model is implemented in MATLAB/Simulink® and it is used to predict the performance of a three phase squirrel single-cage type induction motor/generator in two different cases. The first case is a small 3 meter rotor diameter, 20 kW ocean current turbine with fixed pitch blades, and the second case a 20 …

Effects Of Pharmacological De-Prenylation Of Rhes On Motor Behavior In A Beta-Nitropropionic Acid Animal Model Of Huntington's Disease, Ashley Whitmarsh

LSU New Orleans Theses and Dissertations

Huntington’s disease (HD) is a heritable, neurodegenerative disorder characterized by motor, cognitive, and psychiatric disturbances. The progressive disease is caused by an unstable CAG expansion within the gene that normally encodes for the huntingtin protein (Htt). The expanded mutant form of Htt (mHtt) is expressed ubiquitously throughout patients’ bodies; however, neuronal degeneration is prominent only in the corpus striatum and, to a lesser extent, the cortex. The Ras homolog Rhes is also preferentially localized to the striatum. The putative co-factor Rhes has been shown to act with mHtt to cause neuronal death. Simvastatin, a lipid lowering drug, and zoledronate, a …

From The Back Of A Bus Named Desire, Brenda D. Quant

LSU New Orleans Theses and Dissertations

N/A

Characters Through Time, Alyssa Venezia

Honors Thesis

T. S. Eliot once wrote that we “often find that not only the best, but the most individual parts of [an author’s] work may be those in which the dead poets, his ancestors, assert their immortality most vigorously” (Eliot 37). By focusing on character adaptations, one comes to understand how authors of children’s books are able to adapt classic literature into age-appropriate texts that retain the merits of the original. Five sets of characters shall be analyzed to demonstrate the success of the adaptations presented in children’s literature. In the first, Sir Bedivere from Sir Thomas Malory’s Le Morte Darthur …

The Role Of The State, Multinational Oil Companies, International Law & The International Community: Intersection Of Human Rights & Environmental Degradation Climate Change In The 21st Century Caused By Traditional Extractive Practices, The Amazon Rainforest, Indigenous People And Universal Jurisdiction To Resolve The Accountability Issue, Marcela Cabrera Luna

Master's Theses

Local, national and international conventions that protect indigenous sovereignty and their territories, where many of the resources are extracted from by multinational corporations (MNCs) particularly oil, the number one commodity of the world and cause of climate change, continue to be jeopardized because of the lack of a clear international legal framework that can protect them and potentially hold multinationals accountable for their actions. These practices are causing not only environmental issues to the indigenous and surrounding communities, but climate change is in fact, the real human rights issue of the 21^st century and it affects everyone. By using …