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2015

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Reservoir Rehabilitations: Seeking The Fountain Of Youth, Mark A. Pegg, Kevin L. Pope, Larkin A. Powell, Kelly C. Turek, Jonathan J. Spurgeon, Nathaniel T. Stewart, Nick P. Hogberg, Mark T. Porath Jan 2015

Reservoir Rehabilitations: Seeking The Fountain Of Youth, Mark A. Pegg, Kevin L. Pope, Larkin A. Powell, Kelly C. Turek, Jonathan J. Spurgeon, Nathaniel T. Stewart, Nick P. Hogberg, Mark T. Porath

Nebraska Cooperative Fish and Wildlife Research Unit: Staff Publications

Aging of reservoirs alters the functions, and associated services, of these systems through time. The goal of habitat rehabilitation is often to alter the trajectory of the aging process such that the duration of the desired state is prolonged. There are two important characteristics in alteration of the trajectory—the amplitude relative to current state and the subsequent rate of change, or aging—that ultimately determine the duration of extension for the desired state. Rehabilitation processes largely fall into three main categories: fish community manipulation, water quality manipulation, and physical habitat manipulation. We can slow aging of reservoirs through carefully implemented management …


The Global Status Of Freshwater Fish Age Validation Studies And A Prioritization Framework For Further Research, Jonathan J. Spurgeon, Martin J. Hamel, Kevin L. Pope, Mark A. Pegg Jan 2015

The Global Status Of Freshwater Fish Age Validation Studies And A Prioritization Framework For Further Research, Jonathan J. Spurgeon, Martin J. Hamel, Kevin L. Pope, Mark A. Pegg

Nebraska Cooperative Fish and Wildlife Research Unit: Staff Publications

Age information derived from calcified structures is commonly used to estimate recruitment, growth, and mortality for fish populations. Validation of daily or annual marks on age structures is often assumed, presumably due to a lack of general knowledge concerning the status of age validation studies. Therefore, the current status of freshwater fish age validation studies was summarized to show where additional effort is needed, and increase the accessibility of validation studies to researchers. In total, 1351 original peer-reviewed articles were reviewed from freshwater systems that studied age in fish. Periodicity and age validation studies were found for 88 freshwater species …


Experimental Evaluation Of Rainbow Trout Oncorhynchus Mykiss Predation On Longnose Dace Rhinichthys Cataractae, Kelly C. Turek, Mark A. Pegg, Kevin L. Pope Jan 2015

Experimental Evaluation Of Rainbow Trout Oncorhynchus Mykiss Predation On Longnose Dace Rhinichthys Cataractae, Kelly C. Turek, Mark A. Pegg, Kevin L. Pope

Nebraska Cooperative Fish and Wildlife Research Unit: Staff Publications

Laboratory and in-stream enclosure experiments were used to determine whether rainbow trout Oncorhynchus mykiss influence survival of longnose dace Rhinichthys cataractae. In the laboratory, adult rainbow trout preyed on longnose dace in 42% of trials and juvenile rainbow trout did not prey on longnose dace during the first 6 h after rainbow trout introduction. Survival of longnose dace did not differ in the presence of adult rainbow trout previously exposed to active prey and those not previously exposed to active prey (x21 = 0.28, P = 0.60). In field enclosures, the number of longnose dace decreased at …


Barriers And Bridges To The Integration Of Social–Ecological Resilience And Law, Olivia Odom Green, Ahjond S. Garmestani, Craig R. Allen, Lance H. Gunderson, J.B. Ruhl, Craig A. Arnold, Nicholas A.J. Graham, Barbara Cosens, David G. Angeler, Brian C. Chaffin, C.S. Holling Jan 2015

Barriers And Bridges To The Integration Of Social–Ecological Resilience And Law, Olivia Odom Green, Ahjond S. Garmestani, Craig R. Allen, Lance H. Gunderson, J.B. Ruhl, Craig A. Arnold, Nicholas A.J. Graham, Barbara Cosens, David G. Angeler, Brian C. Chaffin, C.S. Holling

Nebraska Cooperative Fish and Wildlife Research Unit: Staff Publications

There is a fundamental difference between the ways in which ecologists and lawyers view uncertainty: in the study of ecology, uncertainty provides a catalyst for exploration, whereas uncertainty is antithetical to the rule of law. This issue is particularly troubling in environmental management, where the tensions between law and ecology become apparent. Rather than acknowledge uncertainties in management actions, legal frameworks often force a false sense of certainty in linking cause and effect. While adaptive management has been developed to deal with uncertainty, laws and legal wrangling can be obstacles to implementation. In this article, we recommend resilience-based governance – …


Quantifying The Adaptive Cycle, David G. Angeler, Craig R. Allen, Ahjond S. Garmestani, Lance H. Gunderson Jan 2015

Quantifying The Adaptive Cycle, David G. Angeler, Craig R. Allen, Ahjond S. Garmestani, Lance H. Gunderson

Nebraska Cooperative Fish and Wildlife Research Unit: Staff Publications

The adaptive cycle was proposed as a conceptual model to portray patterns of change in complex systems. Despite the model having potential for elucidating change across systems, it has been used mainly as a metaphor, describing system dynamics qualitatively. We use a quantitative approach for testing premises (reorganisation, conservatism, adaptation) in the adaptive cycle, using Baltic Sea phytoplankton communities as an example of such complex system dynamics. Phytoplankton organizes in recurring spring and summer blooms, a well-established paradigm in planktology and succession theory, with characteristic temporal trajectories during blooms that may be consistent with adaptive cycle phases. We used long-term …


Across-Ecoregion Analysis Suggests A Hierarchy Of Ecological Filters That Regulate Recruitment Of A Globally Invasive Fish, Przemek G. Bajer, Timothy K. Cross, Joseph D. Lechelt, Christopher J. Chizinski, Michael J. Weber, Peter W. Sorensen Jan 2015

Across-Ecoregion Analysis Suggests A Hierarchy Of Ecological Filters That Regulate Recruitment Of A Globally Invasive Fish, Przemek G. Bajer, Timothy K. Cross, Joseph D. Lechelt, Christopher J. Chizinski, Michael J. Weber, Peter W. Sorensen

Nebraska Cooperative Fish and Wildlife Research Unit: Staff Publications

Aim -- Even successful invaders are abundant only in a fraction of locales they inhabit. One of the main challenges in invasion ecology is explaining processes that drive these patterns. We investigated recruitment of a globally invasive fish, common carp (Cyprinus carpio), across three ecoregions to determine the role of environmental characteristics, predatory communities and propagule pressure on the invasion process at coarse and fine spatial scales.

Location -- Lakes across Northern Forest, Temperate Forest and Great Plains ecoregions of North America.

Methods -- We used data from 567 lakes to model presence or absence of carp recruitment …


Anticipatory Testimonies: Environmental Disaster In Claudine Jacques's Fictional Prophecies, Julia L. Frengs Jan 2015

Anticipatory Testimonies: Environmental Disaster In Claudine Jacques's Fictional Prophecies, Julia L. Frengs

French Language and Literature Papers

In Caledonian author Claudine Jacques's 2002 novel L'Âge du perroquet-banane, Parabole païenne, a tribal elder warns a man "from elsewhere": "in our country, if you remove a taboo bone, you disrupt the sea, if you touch it without respect you invite a cyclone, if you toss the bones of our elders you provoke a...tidal wave" (54). Although this work is set in a futuristic world after an ambiguous "Great Disaster" on an unnamed Oceanic island, the author manages to allegorically recount the history of the environmental atrocities attributed to the earth's human occupants that have transformed the present reality of …


Nebraska Statewide Forest Action Plan - 2015, Scott Josiah, John Erixson Jan 2015

Nebraska Statewide Forest Action Plan - 2015, Scott Josiah, John Erixson

Nebraska Forest Service: Publications

The Nebraska Forest Action Plan identifies strategic goals based on national objectives collaboratively crafted by both the National Association of State Foresters and the USFS State & Private Forestry Program. The strategic goals and actions identified in this document serve as a blueprint for focusing private, state and federal resources in areas of Nebraska where they will be most effective.


Nebraska Game And Parks Commission 2015 Annual Report Jan 2015

Nebraska Game And Parks Commission 2015 Annual Report

Nebraska Game and Parks Commission: Publications

No abstract provided.


Index To The Senate Journal State Of Colorado: Seventieth General Assembly First Regular Session, Colorado General Assembly Jan 2015

Index To The Senate Journal State Of Colorado: Seventieth General Assembly First Regular Session, Colorado General Assembly

Colorado House and Senate Journals

No abstract provided.


Index To The House Journal State Of Colorado: Seventieth General Assembly First Regular Session At Denver, The State Capitol, Colorado General Assembly Jan 2015

Index To The House Journal State Of Colorado: Seventieth General Assembly First Regular Session At Denver, The State Capitol, Colorado General Assembly

Colorado House and Senate Journals

No abstract provided.


Drag From Fishing Gear Entangling North Atlantic Right Whales, Julie M. Van Der Hoop, Peter Corkeron, John Kenney, Scott Landry, David Morin, Jamison Smith, Michael J. Moore Jan 2015

Drag From Fishing Gear Entangling North Atlantic Right Whales, Julie M. Van Der Hoop, Peter Corkeron, John Kenney, Scott Landry, David Morin, Jamison Smith, Michael J. Moore

United States Department of Commerce: Staff Publications

Lethal and sublethal fishing gear entanglement is pervasive in North Atlantic right whales (Eubalaena glacialis). Entanglement can lead to direct injury and is likely to incur substantial energetic costs. This study (1) evaluates drag characteristics of entangled right whales, (2) contextualizes gear drag measurements for individual whales, and (3) quantifies the benefits of partial disentanglement. A load cell measured drag forces on 15 sets of fishing gear removed from entangled right whales, a towed satellite telemetry buoy, and 200 m of polypropylene line as it was shortened to 25 m, as they were towed behind a vessel at …


Southern Right Whale (Eubalaena Australis) Calf Mortality At Península Valdés, Argentina: Are Harmful Algal Blooms To Blame?, Cara Wilson, A. Viviana Sastre, Monica Hoffmeyer, Victoria J. Rowntree, Spencer E. Fire, Norma H. Santinelli, Soledad Diaz Ovejero, Valeria D'Agostino, Carina F. Maron, Gregory J. Doucette, Margaret H. Broadwater, Zhihong Wang, Nora Montoya, Jon Seger, Frederick R. Alder, Mariano Sironi, Marcela M. Uhart Jan 2015

Southern Right Whale (Eubalaena Australis) Calf Mortality At Península Valdés, Argentina: Are Harmful Algal Blooms To Blame?, Cara Wilson, A. Viviana Sastre, Monica Hoffmeyer, Victoria J. Rowntree, Spencer E. Fire, Norma H. Santinelli, Soledad Diaz Ovejero, Valeria D'Agostino, Carina F. Maron, Gregory J. Doucette, Margaret H. Broadwater, Zhihong Wang, Nora Montoya, Jon Seger, Frederick R. Alder, Mariano Sironi, Marcela M. Uhart

United States Department of Commerce: Staff Publications

Península Valdés (PV) in Argentina is an important calving ground for southern right whales (SRWs, Eubalaena australis). Since 2005, right whale mortality has increased at PV, with most of the deaths (~90%) being calves <3mo old. We investigated the potential involvement of harmful algal blooms (HABs) in these deaths by examining data that include: timing of the SRW deaths, biotoxins in samples from dead SRWs, abundances of the diatom, Pseudo-nitzschia spp., and the dinoflagellate, Alexandrium tamarense, shellfish harvesting closure dates, seasonal availability of whale prey at PV and satellite chlorophyll data. Evidence of the whales’ exposure to HAB toxins includes trace levels of paralytic shellfish toxins (PSTs) and domoic acid (DA) in tissues of some dead whales, and fragments of Pseudo-nitzschia spp. frustules in whale feces. Additionally, whales are present at PV …


Comparison Of Experimental Respiratory Tularemia In Three Nonhuman Primate Species, Audrey R. Glynn, Derron A. Alves, Ondraya Frick, Rebecca Erwin-Cohen, Aimee Porter, Sarah Norris, David Waag, Aysegul Nalca Jan 2015

Comparison Of Experimental Respiratory Tularemia In Three Nonhuman Primate Species, Audrey R. Glynn, Derron A. Alves, Ondraya Frick, Rebecca Erwin-Cohen, Aimee Porter, Sarah Norris, David Waag, Aysegul Nalca

United States Army: Publications

Tularemia is a zoonotic disease caused by Francisella tularensis, which is transmitted to humans most commonly by contact with infected animals, tick bites, or inhalation of aerosolized bacteria. F. tularensis is highly infectious via the aerosol route; inhalation of as few as 10–50 organisms can cause pneumonic tularemia. Left untreated, the pneumonic form has more than >30% case-fatality rate but with early antibiotic intervention can be reduced to 3%. This study compared tularemia disease progression across three species of nonhuman primates [African green monkey (AGM), cynomolgus macaque (CM), and rhesus macaque (RM)] following aerosolized F. tularensis Schu S4 exposure. …


Particle-Based Platforms For Malaria Vaccines, Yimin Wu, David L. Narum, Sylvain Fleury, Gary Jennings, Anjali Yadava Jan 2015

Particle-Based Platforms For Malaria Vaccines, Yimin Wu, David L. Narum, Sylvain Fleury, Gary Jennings, Anjali Yadava

United States Army: Publications

Recombinant subunit vaccines in general are poor immunogens likely due to the small size of pep-tides and proteins, combined with the lack or reduced presentation of repetitive motifs and missing complementary signal(s) for optimal triggering of the immune response. Therefore, recombinant sub-unit vaccines require enhancement by vaccine delivery vehicles in order to attain adequate protective immunity. Particle-based delivery platforms, including particulate antigens and particulate adjuvants,are promising delivery vehicles for modifying the way in which immunogens are presented to both theinnate and adaptive immune systems. These particle delivery platforms can also co-deliver non-specific immunostimodulators as additional adjuvants. This paper reviews efforts …


Correlation Of Foraminal Area And Response To Cervical Nerve Root Injections, Wilson Z. Ray, Syed Akbari, Lubdha M. Shah, Erica Bisson Jan 2015

Correlation Of Foraminal Area And Response To Cervical Nerve Root Injections, Wilson Z. Ray, Syed Akbari, Lubdha M. Shah, Erica Bisson

Open Access Publications

No abstract provided.


Kappa Opioid Receptor-Induced Aversion Requires P38 Mapk Activation In Vta Dopamine Neurons, Jonathan M. Ehrich, Daniel I. Messinger, Cerise R. Knakal, Jamie R. Kuhar, Selena S. Schatteuer, Michael R. Bruchas, Larry S. Zweifel, Brigitte L. Kieffer, Paul E M Phillips, Charles Chavkin Jan 2015

Kappa Opioid Receptor-Induced Aversion Requires P38 Mapk Activation In Vta Dopamine Neurons, Jonathan M. Ehrich, Daniel I. Messinger, Cerise R. Knakal, Jamie R. Kuhar, Selena S. Schatteuer, Michael R. Bruchas, Larry S. Zweifel, Brigitte L. Kieffer, Paul E M Phillips, Charles Chavkin

Open Access Publications

No abstract provided.


Neuronal-Targeted Tfeb Accelerates Lysosomal Degradation Of App, Reducing Aβ Generation And Amyloid Plaque Pathogenesis, Qingli Xiao, Ping Yan, Xiucui Ma, Haiyan Liu, Ronaldo Perez, Alec Zhu, Ernesto Gonzales, Danielle L. Tripoli, Leah Czerniewski, Andrea Ballabio, John R. Cirrito, Abhinav Diwan, Jin-Moo Lee Jan 2015

Neuronal-Targeted Tfeb Accelerates Lysosomal Degradation Of App, Reducing Aβ Generation And Amyloid Plaque Pathogenesis, Qingli Xiao, Ping Yan, Xiucui Ma, Haiyan Liu, Ronaldo Perez, Alec Zhu, Ernesto Gonzales, Danielle L. Tripoli, Leah Czerniewski, Andrea Ballabio, John R. Cirrito, Abhinav Diwan, Jin-Moo Lee

Open Access Publications

No abstract provided.


Inflammatory Pain Promotes Increased Opioid Self-Administration: Role Of Dysregulated Ventral Tegmental Area Μ Opioid Receptors, Lucia Hipolito, Adrianne Wilson-Poe, Yolanda Campos-Jurado, Elaine Zhong, Jose Gonzalez-Romero, Laszlo Virag, Robert Whittington, Sandra D. Comer, Susan M. Carlton, Brendan M. Walker, Michael R. Bruchas, Jose A. Moron Jan 2015

Inflammatory Pain Promotes Increased Opioid Self-Administration: Role Of Dysregulated Ventral Tegmental Area Μ Opioid Receptors, Lucia Hipolito, Adrianne Wilson-Poe, Yolanda Campos-Jurado, Elaine Zhong, Jose Gonzalez-Romero, Laszlo Virag, Robert Whittington, Sandra D. Comer, Susan M. Carlton, Brendan M. Walker, Michael R. Bruchas, Jose A. Moron

Open Access Publications

No abstract provided.


Targeting Cd226/Dnax Accessory Molecule-1 (Dnam-1) In Collagen-Induced Arthritis Mouse Models, Muriel Elhai, Gilles Chiocchia, Carmen Marchiol, Franck Lager, Gilles Renault, Marco Colonna, Guenter Bernhardt, Yannick Allanore, Jerome Avouac Jan 2015

Targeting Cd226/Dnax Accessory Molecule-1 (Dnam-1) In Collagen-Induced Arthritis Mouse Models, Muriel Elhai, Gilles Chiocchia, Carmen Marchiol, Franck Lager, Gilles Renault, Marco Colonna, Guenter Bernhardt, Yannick Allanore, Jerome Avouac

Open Access Publications

No abstract provided.


Scientific And Regulatory Policy Committee (Srpc) Review*: Interpretation And Use Of Cell Proliferation Data In Cancer Risk Assessment, Charles E. Wood, Renee R. Hukkanen, Radhakrisha Sura, David Jacobson-Kram, Thomas Nolte, Marielle Odin, Samuel M. Cohen Jan 2015

Scientific And Regulatory Policy Committee (Srpc) Review*: Interpretation And Use Of Cell Proliferation Data In Cancer Risk Assessment, Charles E. Wood, Renee R. Hukkanen, Radhakrisha Sura, David Jacobson-Kram, Thomas Nolte, Marielle Odin, Samuel M. Cohen

United States Food and Drug Administration: Publications

Increased cell proliferation is a central key event in the mode of action for many non-genotoxic carcinogens, and quantitative cell proliferation data play an important role in the cancer risk assessment of many pharmaceutical and environmental compounds. Currently, there is limited unified information on assay standards, reference values, targeted applications, study design issues, and quality control considerations for proliferation data. Here, we review issues in measuring cell proliferation indices, considerations for targeted studies, and applications within current risk assessment frameworks. As the regulatory environment moves toward more prospective evaluations based on quantitative pathway-based models, standardiza- tion of proliferation assays will …


Relationship Between Heat-Labile Enterotoxin Secretion Capacity And Virulence In Wild Type Porcine-Origin Enterotoxigenic Escherichia Coli Strains, Prageeth Wijemanne, Jun Xing, Emil M. Berberov, David H. Francis, Rodney A. Moxley Jan 2015

Relationship Between Heat-Labile Enterotoxin Secretion Capacity And Virulence In Wild Type Porcine-Origin Enterotoxigenic Escherichia Coli Strains, Prageeth Wijemanne, Jun Xing, Emil M. Berberov, David H. Francis, Rodney A. Moxley

School of Veterinary and Biomedical Sciences: Faculty Publications

Heat-labile enterotoxin (LT) is an important virulence factor secreted by some strains of enterotoxigenic Escherichia coli (ETEC). The prototypic human-origin strain H10407 secretes LT via a type II secretion system(T2SS). We sought to determine the relationship between the capacity to secrete LT and virulence in porcine-origin wild type (WT) ETEC strains. Sixteen WT ETEC strains isolated from cases of severe diarrheal disease were analyzed by GM1ganglioside enzyme- linked immunosorbent assay tomeasure LT concentrations in culture supernatants. All strains had detectable LT in supernatants by 2 h of culture and 1 strain, which was particularly virulent in gnotobiotic piglets (3030-2), had …


Temperatures Of Storage Areas In Large Animal Veterinary Practice Vehicles In The Summer And Comparison With Drug Manufacturers’ Storage Recommendations, Jeff D. Ondrak, Meredyth L. Jones, Virginia R. Fajt Jan 2015

Temperatures Of Storage Areas In Large Animal Veterinary Practice Vehicles In The Summer And Comparison With Drug Manufacturers’ Storage Recommendations, Jeff D. Ondrak, Meredyth L. Jones, Virginia R. Fajt

School of Veterinary and Biomedical Sciences: Faculty Publications

Background: Large animal veterinarians carry drugs in their practice vehicles in storage areas that are not typically refrigerated. The most common upper limits of manufacturers’ storage temperatures for United States (U.S.)-approved non-refrigerated drugs are 25 or 30 °C. Because ambient temperatures in many locations in the U.S. exceed these temperatures during the summer, we measured storage area temperatures over 4 months in the summer of 2013 to evaluate the extent to which labeled storage temperatures are exceeded.

Methods: A convenience sample of 12 vehicles from 5 central Texas practices and 12 vehicles from 4 south central Nebraska practices was …


Now & Then (Volume 30, Issue 02, 2015), Center Of Excellence For Appalachian Studies And Services, East Tennessee State University Jan 2015

Now & Then (Volume 30, Issue 02, 2015), Center Of Excellence For Appalachian Studies And Services, East Tennessee State University

Now & Then: The Appalachian Magazine

Now & Then: The Appalachian Magazine, Volume 30, Issue 02, published in 2015. The theme of this issue is The Best of 30 Years, Part I. This issue presents the first part of a retrospective collection, drawing from selected works published between 1984 and 1999 to revisit major themes in Appalachian studies. It brings together essays, interviews, and narratives that reflect on topics such as health, place, and cultural tradition, community leadership, labor activism, media, religion, and humor, illustrating the breadth of concerns that have shaped the magazine's earlier volumes. The selections emphasize lived experience, storytelling, and regional identity, …


University Of Nebraska- Lincoln: Fact Book Jan 2015

University Of Nebraska- Lincoln: Fact Book

University of Nebraska-Lincoln Administration: Reports, Papers, Publications, and Presentations

Fact Book Table of Contents

Front Cover............................................................. 1

Introduction ........................................... 2

Table of Contents.................................................................. 4

General Information

University of Nebraska-Lincoln Core Values (LEADERS)................................... 7

The Role of the University of Nebraska-Lincoln ....................................... 8

The Missions of the University of Nebraska-Lincoln ......................................... 8

Teaching........................................................................................................... 9

Research.................................................................................................. 10

Service........................................................................................... 10

Institutional and Professional Accreditations................................................. 11

University of Nebraska-Lincoln Administrative Organization Chart .................. 14

Student Credit Hours (SCH)

Total SCH: Fall Semester Since 1979 ...................................................... 15

Total SCH: Spring Semester Since 1993 .......................................................... 16

SCH by College and Course Level, Fall and Spring Semester, 5 Year Trend ... 17

SCH by College and …


Detection, Occurrence And Fate Of Emerging Contaminants In Agricultural Environments, Daniel D. Snow, David A. Cassada, Shannon L. Bartelt-Hunt, Xu Li, Matteo D'Alessio, Rachel Levine, Yun Zhang, J. Brett Sallach Jan 2015

Detection, Occurrence And Fate Of Emerging Contaminants In Agricultural Environments, Daniel D. Snow, David A. Cassada, Shannon L. Bartelt-Hunt, Xu Li, Matteo D'Alessio, Rachel Levine, Yun Zhang, J. Brett Sallach

Nebraska Water Center: Faculty Publications

A total of 43 papers published in 2014 were reviewed ranging from detailed descriptions of analytical methods, to fate and occurrence studies, to measuring and predicting biological effects for a wide variety of emerging contaminants likely to occur in agricultural environments. New methods and studies on veterinary pharmaceuticals, natural and synthetics steroids, and antibiotic resistance genes in agricultural environments continue to expand our knowledge base on the occurrence and potential impacts of these compounds. This review is divided into the following sections: Introduction, Analytical Methods, Occurrence and Fate, Antibiotic Resistance Genes, and Risk Assessment.


The Taurine Biosynthetic Pathway Of Microalgae, Rahul Tevatia, James Allen, Deepak Rudrappa, Derrick White, Thomas E. Clemente, Heriberto Cerutti, Yaşar Demirel, Paul H. Blum Jan 2015

The Taurine Biosynthetic Pathway Of Microalgae, Rahul Tevatia, James Allen, Deepak Rudrappa, Derrick White, Thomas E. Clemente, Heriberto Cerutti, Yaşar Demirel, Paul H. Blum

Center for Plant Science Innovation: Faculty Publications

Taurine (2-aminoethanesulfonic acid) is an amino acid–like compound widely distributed in animals and an essential nutrient in some species. Targeted metabolomics of marine and freshwater microalgae combined with medium supplementation identified biosynthetic pathway intermediates and necessary catalytic activities. Genomic analysis was then used to predict the first taurine biosynthetic pathway in these organisms. MRM-based electrospray ionization (ESI) LC–MS/MS analysis demonstrated that taurine is synthesized using a carbon backbone from L-serine combined with sulfur derived from sulfate. Metabolite analysis showed a nonuniform pattern in levels of pathway intermediates that were both species and supplement dependent. While increased culture salinity raised taurine …


Fossil Population Structure And Mortality Analysis Of The Cave Bears From Urşilor Cave, North-Western Romania, Marius Robu Jan 2015

Fossil Population Structure And Mortality Analysis Of The Cave Bears From Urşilor Cave, North-Western Romania, Marius Robu

KIP Articles

Research in cave bear palaeobiology focusing on population structure and mortality analysis may improve our understanding regarding the ecology of this species which vanished at the end of Marine Isotope Stage (MIS) 3, prior to Last Glacial Maximum (LGM), if assessed populations are large enough. Such population is available in Urşilor Cave, from north-western Romania, known as one of the most rich and complex European MIS3 cave bear sites. From the palaeontological excavation, situated at the lower level of the cave (= Scientific Reserve), more than 210 cave bear isolated lower molars, 160 mandibles and almost 180 canines were extracted …


Discovery Of Alternative Artemisinin Binding Sites In Plasmodium Falciparum Atpase-6, Shuneize Elizabeth Slater Jan 2015

Discovery Of Alternative Artemisinin Binding Sites In Plasmodium Falciparum Atpase-6, Shuneize Elizabeth Slater

Electronic Theses and Dissertations

Malaria is a fatal yet preventable and treatable disease. It is commonly spread through the bite of an infected Anopheles mosquito. Malaria parasites belong to the Plasmodium genus and can be caused by the falciparum, malariae, ovale, vivax, and knowlesi species. Artemisinin is an endoperoxide lactone extracted from qinghaosu (Artemisia annua L. or sweet wormwood). It and its derivatives possess uncharacteristically rapid action against Plasmodium falciparum. Artemisinin is unique in its effectiveness in deadly cerebral malaria. The endoperoxide bridge is crucial for its antimalarial activity; however, how it aids in killing the parasite is unknown. While there are multiple suggested …


Striking The Balance: Challenges And Perspectives For The Protected Areas Network In Northeastern European Russia, Svetlana V. Degteva, Vasily I. Ponomarev, Sasha W. Eisenman, Vyacheslav Dushenkov Jan 2015

Striking The Balance: Challenges And Perspectives For The Protected Areas Network In Northeastern European Russia, Svetlana V. Degteva, Vasily I. Ponomarev, Sasha W. Eisenman, Vyacheslav Dushenkov

Publications and Research

Increasing anthropogenic pressure on the largest remaining tracts of old-growth boreal forest in Europe necessitates additional conservation of ecosystems and biodiversity in northeastern European Russia. In a regional network comprising 8 % of the Nenets Autonomous District and 13.5 % of the Komi Republic, 248 areas have varying protected statuses as state nature reserves (zapovedniks), national parks, reserves/sanctuaries (zakazniks), or natural monuments. Due to increased natural resource extraction in this relatively pristine area, designation of additional protected areas is critical for the protection of key ecological sites. The history of ecological preservation in these regions is herein described, and recent …