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Review: Checking Out Chekhov: A Guide To The Plays For Actors, Directors, And Readers, Valleri J. Robinson

Russian Language Journal

Sharon Carnicke’s Checking out Chekhov: A Guide to the Plays for Actors, Directors, and Readers provides a succinct foundation for understanding how to read Chekhov’s mature plays for theatre practitioners and students who so often encounter his work. As one of the most often produced and adapted playwrights in professional and academic theatres, Chekhov must be produced by theatre professionals that have a handle on how to think, talk, and, ultimately, produce Chekhov. While many books aimed at this audience offer interpretive readings, analytical strategies, and historical contexts for engaging with Chekhov’s unique dramatic worlds, none approach Chekhov using Carnicke’s …

Full Issue

Russian Language Journal

No abstract provided.

Annual Report Town Of Center Harbor, New Hampshire For Year Ending December 31, 2014., Center Harbor Town Representatives

Center Harbor, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

Dendritic And Langerhans Cells Respond To Aβ Peptides Differently: Implication For Ad Immunotherapy, Jiang Cheng, Xiaoyang Lin, David Morgan, Marcia Gordon, Xi Chen, Zhen-Hai Wang, Hai-Ning Li, Lan-Jie He, Shu-Feng Zhou, Chuanhai Cao

Molecular Pharmacology & Physiology Faculty Publications

Both wild-type and mutated beta-amyloid (Aβ) peptides can elicit an immune response when delivered subcutaneously. However, only mutated forms of Aβ can sensitize dendritic cells when administered intravenously or intraperitoneally. To understand the role of mutation and delivery routes in creating immune responses, and the function of dendritic cells as therapeutic agents, we used fluorescent-conjugated WT Aβ1-40 (WT40) and artificially mutated Aβ1-40 (22W40) peptides to treat dendritic and Langerhans cells from young and/or old mice at different time points. The cell types were analyzed by flow cytometry and confocal microscopy to identify differences in function and antigen presentation, and Luminex …

Familiarity Breeds Contempt: Combining Proximity Loggers And Gps Reveals Female White-Tailed Deer (Odocoileus Virginianus) Avoiding Close Contact With Neighbors, Marie I. Tosa, Eric M. Schauber, Clayton K. Nielsen

Publications

Social interactions can influence infectious disease dynamics, particularly for directly transmitted pathogens. Therefore, reliable information on contact frequency within and among groups can better inform disease modeling and management. We compared three methods of assessing contact patterns: (1) space-use overlap (volume of interaction [VI]), (2) direct contact rates measured by simultaneous global positioning system (GPS) locations (apart), and (3) direct contact rates measured by proximity loggers (PLs; 1-m detection) among female white-tailed deer (Odocoileus virginianus). We calculated the PL∶GPS contact ratios to see whether both devices reveal similar contact patterns and thus predict similar pathogen transmission patterns. Contact …

Survival And Dispersal Of White-Tailed Deer In The Agricultural Landscape Of East-Central Illinois, Charles W. Anderson, Clayton K. Nielsen, Eric M. Schauber

Publications

White-tailed deer (Odocoileus virginianus) are a keystone species throughout their range in North America. The recent presence of diseases such as chronic wasting disease and bovine tuberculosis in Midwestern North America dictates the examination of influences of those diseases on deer populations, and survival and dispersal rates are important parameters when modeling potential disease spread. We quantified survival and dispersal rates of 105 deer in agriculturally-dominated east-central Illinois during 2005-2009. We used Program MARK to estimate rates of annual survival, seasonal survival, and dispersal for fawn, yearling, and adult age-classes. Male and female seasonal (winter/spring [16 Dec–14 May], summer [15 …

Ranging Behavior Of Marsh Rice Rats In A Southern Illinois Wetland Complex, Scott A. Cooney, Eric M. Schauber, Eric Hellgren

Publications

The marsh rice rat (Oryzomys palustris) inhabits wetlands that are often fragmented and isolated by upland cover types. Persistence of marsh rice rat populations and metapopulations likely depends on their ability to enter and traverse the upland matrix, yet basic information, such as home-range size and landcover use patterns, is lacking. Our goal was to quantify home-range size and habitat selection by marsh rice rats in southern Illinois. Between March and November 2011, we radiocollared 21 male rice rats (8 subadults and 13 adults) that were each located 7 to 24 times each via triangulation and homing. We estimated home-range …

Orchid–Pollinator Interactions And Potential Vulnerability To Biological Invasion, Adam D. Chupp, Loretta L. Battaglia, Eric M. Schauber, Sedonia D. Sipes

Publications

Mutualistic relationships between plants and their pollinators have played a major role in the evolution of biodiversity. While the vulnerability of these relationships to environmental change is a major concern, studies often lack a framework for predicting impacts from emerging threats (e.g. biological invasions). The objective of this study was to determine the reliance of Platanthera ciliaris (orange-fringed orchid) on Papilio palamedes (Palamedes swallowtail butterfly) for pollination and the relative availability of alternative pollinators. Recent declines of P. palamedes larval host plants due to laurel wilt disease (LWD) could endanger P. ciliaris populations that rely heavily on this butterfly for …

Altered Neurotransmission Prior To Cognitive Decline In Aβpp/Ps1 Mice, A Model Of Alzheimer's Disease, Kevin N. Hascup, Erin R. Hascup

Articles

Indirect evidence supports altered glutamate signaling with Alzheimer's disease, however, it is not known if glutamate neurotransmission is impacted prior to cognitive decline. We examined cognition and glutamate neurotransmission in 2-4 month AβPP/PS1, an Alzheimer's disease model, and age-matched control mice. There were no differences in learning and memory as assessed by Morris water maze. However, in vivo electrochemical measures of potassium-evoked glutamate release in the CA1, but not the CA3 or dentate, was significantly elevated in AβPP/PS1 mice. These data support changes in the glutamatergic system that precedes cognitive decline in a mouse model of Alzheimer's disease.

2015-2016 Southern Illinois University Bulletin Carbondale Campus (Undergraduate Catalog), Southern Illinois University Carbondale

SIU Bulletins and Course Catalogs Archives

No abstract provided.

2015-2016 Southern Illinois University Bulletin Carbondale Campus (Graduate Catalog), Southern Illinois University Carbondale

SIU Bulletins and Course Catalogs Archives

No abstract provided.

Evaluation Of L-Methionine Bioavailability In Nursery Pigs, Jina Lim

Theses and Dissertations--Animal and Food Sciences

DL-Methionine (Met) has been conventionally used in swine diets with assumption of similar bioefficacy with L-Met. However, because L-Met is the form that is utilized by animals for protein synthesis, L-Met could, theoretically, be more available. Four experiments were conducted to evaluate L-Met bioavailability in nursery pigs with 21-day growth trials. A total of 105,105,112 and 84 crossbred pigs were used in Exp. 1, 2, 3 and 4, respectively. Each experiment had a low Met basal diet and 3 levels of the Met sources (DL-Met and L-Met). In addition to the basal diet, supplementation levels were 0.053%, 0.107% and 0.160% …

Clarksville, New Hampshire 2014 Annual Town Report School Directors Annual Report., Clarksville Town Representatives

Clarksville, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

The Unlikely Antidote: Political Tension And Political Health In The Modern Western Tradition And The United States Of America, Savannah Berger

Government and International Relations Honors Papers

At the most elementary level, this honors study is concerned with political tension and its ability to procure political health. The study begins with a discussion in political theory, examining the contemporary theory of agonism, which accepts conflict as an inevitable fact of pluralist political society and defends it as necessary for the maintenance of democracy. The study identifies agonism’s origins in the ancient Greek agon, but also emphasizes that the first formal exposition of agonal political ideas comes in Machiavelli’s Discourses on Livy. It continues to work in the realm of theory, charting moments of appreciation of agonal ideas, …

Healthy Outside-Healthy Inside: The Human Health & Well-Being Benefits Of Alberta's Protected Areas - Towards A Benefits-Based Management Agenda, Christopher J. Lemieux, Sean T. Doherty, Paul F.J. Eagles, Joyce Gould, Glen T. Hvenegaard, Elizabeth (Lisa) Nisbet, Mark W. Groulx

Geography and Environmental Studies Faculty Publications

This report details the results of an empirical study that examined perceived health and well-being motives and benefits among visitors to a sample of Alberta’s parks and protected areas. The study revealed several major findings with important policy and management implications. First, the human health and well-being benefits that the visitors expected to receive from visits were perceived to be a major personal motivation in the choice to visit Alberta protected areas. The most important motivation factors identified by respondents were psychological and emotional well-being (89.1% of visitors ranked this important), social well-being (88.3%), physical well-being (80.3%), and environmental well-being …

Louisiana Agriculture Winter, 2015

Louisiana Agriculture

No abstract provided.

2015 Louisiana Summary: Agriculture And Natural Resources, Lsu Agcenter

Louisiana Summary: Agriculture and Natural Resources

This publication tabulates the value of Louisiana agriculture in 2015. Agents and specialists of the Louisiana Cooperative Extension Service, as well as other agencies – both private and public – compiled the data. Their analyses focus on the animal, forestry, fisheries, plant and wildlife commodities that comprise our vital agricultural industry. Agricultural and natural resource industries contribute significantly to our state’s economy with the potential for increased economic benefits and job creation through value-added processing in urban and rural communities throughout Louisiana.

After three consecutive years of nearly ideal growing conditions and record production, the 2015 production year was one …

Blueberries Improve Glucose Tolerance Without Altering Body Composition In Obese Postmenopausal Mice, Carrie M. Elks, Jennifer D. Terrebonne, Donald K. Ingram, Jacqueline M. Stephens

Faculty Publications

© 2015 The Obesity Society. Objective Metabolic syndrome (MetS) risk increases significantly during menopause and remains elevated postmenopause. Several botanicals, including blueberries (BB), have been shown to delay MetS progression, but few studies have been conducted in postmenopausal animal models. Here, the effects of BB supplementation on obese postmenopausal mice using a chemically induced menopause model were examined. Methods After induction of menopause, mice were fed a high-fat diet or the same diet supplemented with 4% BB powder for 12 weeks. Body weight and body composition were measured, and mice were subjected to glucose and insulin tolerance tests. Serum triglycerides …

Isothiocyanate-Rich Moringa Oleifera Extract Reduces Weight Gain, Insulin Resistance, And Hepatic Gluconeogenesis In Mice, Patricio Rojas-Silva, Tugba Boyunegmez Tumer, Peter Kuhn, Allison J. Richard, Shawna Wicks, Jacqueline M. Stephens, Zhong Wang, Randy Mynatt, William Cefalu, Ilya Raskin

Faculty Publications

© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. Scope: Moringa oleifera (moringa) is tropical plant traditionally used as an antidiabetic food. It produces structurally unique and chemically stable moringa isothiocyanates (MICs) that were evaluated for their therapeutic use in vivo. Methods and results: C57BL/6L mice fed very high fat diet (VHFD) supplemented with 5% moringa concentrate (MC, delivering 66 mg/kg/d of MICs) accumulated fat mass, had improved glucose tolerance and insulin signaling, and did not develop fatty liver disease compared to VHFD-fed mice. MC-fed group also had reduced plasma insulin, leptin, resistin, cholesterol, IL-1β, TNFα, and lower hepatic glucose-6-phosphatase …

Tetrakis(P-Carboranylthio-Tetrafluorophenyl)Chlorin (Tpfc): Application For Photodynamic Therapy And Boron Neutron Capture Therapy, Ryo Hiramatsu, Shinji Kawabata, Hiroki Tanaka, Yoshinori Sakurai, Minoru Suzuki, Koji Ono, Shin Ichi Miyatake, Toshihiko Kuroiwa, Erhong Hao, M. Graça H. Vicente

Faculty Publications

© 2014 Wiley Periodicals, Inc. Carboranyl-containing chlorins have emerged as promising dual sensitizers for use in both photodynamic therapy (PDT) and boron neutron capture therapy (BNCT), by virtue of their known tumor affinity, low cytotoxicity in dark conditions, and their strong absorptions in the red region of the optical spectrum. Tetrakis(p-carboranylthio-tetrafluorophenyl)chlorin (TPFC) is a new synthetic carboranyl-containing chlorin of high boron content (24% by weight). To evaluate TPFC's applicability as sensitizer for both PDT and BNCT, we performed an in vitro and in vivo study using F98 rat glioma cells and F98 rat glioma-bearing brain tumor models. For the in …

Social Transitions Cause Rapid Behavioral And Neuroendocrine Changes, Karen P. Maruska

Faculty Publications

© 2015 The Author 2015. Published by Oxford University Press on behalf of the Society for Integrative and Comparative Biology. All rights reserved. In species that form dominance hierarchies, there are often opportunities for low-ranking individuals to challenge high-ranking ones, resulting in a rise or fall in social rank. How does an animal rapidly detect, process, and then respond to these social transitions? This article explores and summarizes how these social transitions can rapidly (within 24 h) impact an individual's behavior, physiology, and brain, using the African cichlid fish, Astatotilapia burtoni, as a model. Male A. burtoni form hierarchies in …

Suppression Of Rnai By Dsrna-Degrading Rnaseiii Enzymes Of Viruses In Animals And Plants, Isabel Weinheimer, Yaming Jiu, Minna Liisa Rajamäki, Olli Matilainen, Jukka Kallijärvi, Wilmer J. Cuellar, Rui Lu, Mart Saarma, Carina I. Holmberg, Jussi Jäntti, Jari P.T. Valkonen

Faculty Publications

© 2015 Weinheimer et al. Certain RNA and DNA viruses that infect plants, insects, fish or poikilothermic animals encode Class 1 RNaseIII endoribonuclease-like proteins. dsRNA-specific endoribonuclease activity of the RNaseIII of rock bream iridovirus infecting fish and Sweet potato chlorotic stunt crinivirus (SPCSV) infecting plants has been shown. Suppression of the host antiviral RNA interference (RNAi) pathway has been documented with the RNaseIII of SPCSV and Heliothis virescens ascovirus infecting insects. Suppression of RNAi by the viral RNaseIIIs in non-host organisms of different kingdoms is not known. Here we expressed PPR3, the RNaseIII of Pike-perch iridovirus, in the non-hosts Nicotiana …

Co-Evolution Of Proteins And Solutions: Protein Adaptation Versus Cytoprotective Micromolecules And Their Roles In Marine Organisms, Paul H. Yancey, Joseph F. Siebenaller

Faculty Publications

© 2015. Published by The Company of Biologists Ltd. Organisms experience a wide range of environmental factors such as temperature, salinity and hydrostatic pressure, which pose challenges to biochemical processes. Studies on adaptations to such factors have largely focused on macromolecules, especially intrinsic adaptations in protein structure and function. However, micromolecular cosolutes can act as cytoprotectants in the cellular milieu to affect biochemical function and they are now recognized as important extrinsic adaptations. These solutes, both inorganic and organic, have been best characterized as osmolytes, which accumulate to reduce osmotic water loss. Singly, and in combination, many cosolutes have properties …

Standards For Plant Synthetic Biology: A Common Syntax For Exchange Of Dna Parts, Nicola J. Patron, Diego Orzaez, Sylvestre Marillonnet, Heribert Warzecha, Colette Matthewman, Mark Youles, Oleg Raitskin, Aymeric Leveau, Gemma Farré, Christian Rogers, Alison Smith, Julian Hibberd, Alex A.R. Webb, James Locke, Sebastian Schornack, Jim Ajioka, David C. Baulcombe, Cyril Zipfel, Sophien Kamoun, Jonathan D.G. Jones, Hannah Kuhn, Silke Robatzek, H. Peter Van Esse, Dale Sanders, Giles Oldroyd, Cathie Martin, Rob Field, Sarah O'Connor, Samantha Fox, Brande Wulff, Ben Miller, Andy Breakspear, Guru Radhakrishnan

Faculty Publications

© 2015 New Phytologist Trust. Inventors in the field of mechanical and electronic engineering can access multitudes of components and, thanks to standardization, parts from different manufacturers can be used in combination with each other. The introduction of BioBrick standards for the assembly of characterized DNA sequences was a landmark in microbial engineering, shaping the field of synthetic biology. Here, we describe a standard for Type IIS restriction endonuclease-mediated assembly, defining a common syntax of 12 fusion sites to enable the facile assembly of eukaryotic transcriptional units. This standard has been developed and agreed by representatives and leaders of the …

Diosgenin, 4-Hydroxyisoleucine, And Fiber From Fenugreek: Mechanisms Of Actions And Potential Effects On Metabolic Syndrome, Scott Fuller, Jacqueline M. Stephens

Faculty Publications

© 2015 American Society for Nutrition. Metabolic syndrome and its complications continue to rise in prevalence and show no signs of abating in the immediate future. Therefore, the search for effective treatments is a high priority in biomedical research. Products derived from botanicals have a time-honored history of use in the treatment of metabolic diseases including type 2 diabetes. Trigonella foenum-graecum, commonly known as fenugreek, is an annual herbaceous plant that has been a staple of traditional herbal medicine in many cultures. Although fenugreek has been studied in both clinical and basic research settings, questions remain about its efficacy and …

Fat In Flames: Influence Of Cytokines And Pattern Recognition Receptors On Adipocyte Lipolysis, Ryan W. Grant, Jacqueline M. Stephens

Faculty Publications

© 2015 the American Physiological Society. Adipose tissue has the largest capacity to store energy in the body and provides energy through the release of free fatty acids during times of energy need. Different types of immune cells are recruited to adipose tissue under various physiological conditions, indicating that these cells contribute to the regulation of adipose tissue. One major pathway influenced by a number of immune cells is the release of free fatty acids through lipolysis during both physiological (e.g., cold stress) and pathophysiological processes (e.g., obesity, type 2 diabetes). Adipose tissue expansion during obesity leads to immune cell …

Are Receptor Concentrations Correlated Across Tissues Within Individuals? A Case Study Examining Glucocorticoid And Mineralocorticoid Receptor Binding, Christine R. Lattin, Daniel E. Keniston, J. Michael Reed, L. Michael Romero

Faculty Publications

Copyright © 2015 by the Endocrine Society. Hormone receptors are a necessary (although not sufficient) part of the process through which hormones like corticosterone create physiological responses. However, it is currently unknown to what extent receptor concentrations across different target tissues may be correlated within individual animals. In this study, we examined this question using a large dataset of radioligand binding data for glucocorticoid receptors (GRs) and mineralocorticoid receptors (MRs) in 13 different tissues in the house sparrow (Passer domesticus) (n = 72). Our data revealed that individual house sparrows tended to exhibit higher or lower receptor binding across all …

Discordance Between Morphological And Molecular Species Boundaries Among Caribbean Species Of The Reef Sponge Callyspongia, Melissa B. Debiasse, Michael E. Hellberg

Faculty Publications

© 2015 The Authors. Sponges are among the most species-rich and ecologically important taxa on coral reefs, yet documenting their diversity is difficult due to the simplicity and plasticity of their morphological characters. Genetic attempts to identify species are hampered by the slow rate of mitochondrial sequence evolution characteristic of sponges and some other basal metazoans. Here we determine species boundaries of the Caribbean coral reef sponge genus Callyspongia using a multilocus, model-based approach. Based on sequence data from one mitochondrial (COI), one ribosomal (28S), and two single-copy nuclear protein-coding genes, we found evolutionarily distinct lineages were not concordant with …

Serotonin 5-Ht2 Receptor Activation Prevents Allergic Asthma In A Mouse Model, Felix Nau, Justin Miller, Jordy Saravia, Terry Ahlert, Bangning Yu, Kyle I. Happel, Stephania A. Cormier, Charles D. Nichols

Faculty Publications

© 2015 the American Physiological Society. Asthma is an inflammatory disease of the lung characterized by airways hyper-responsiveness (AHR), inflammation, and mucus hyperproduction. Current main-stream therapies include bronchodilators that relieve bronchoconstriction and inhaled glucocorticoids to reduce inflammation. The small molecule hormone and neurotransmitter serotonin has long been known to be involved in inflammatory processes; however, its precise role in asthma is unknown. We have previously established that activation of serotonin 5-hydroxytryptamine (5-HT)2A receptors has potent anti-inflammatory activity in primary cultures of vascular tissues and in the whole animal in vasculature and gut tissues. The 5-HT2A receptor agonist, (R)-2,5-dimethoxy-4-iodoamphetamine [(R)-DOI] is …

Discovery And Confirmation Of Genes/Proteins Associated With Maize Aflatoxin Resistance, Z. Y. Chen, K. Rajasekaran, R. L. Brown, R. J. Sayler, D. Bhatnagar

Faculty Publications

Maize (Zea mays L.) is one of the major crops susceptible to Aspergillus flavus infection and subsequent aflatoxin contamination. Many earlier studies indicated the roles of kernel proteins, especially constitutively expressed proteins, in maize resistance to A. flavus infection and aflatoxin production. In this review, we examined the past and current efforts in identifying maize genes and proteins from kernel, rachis, and silk tissues that may play an important role in resistance to A. flavus infection and aflatoxin contamination, as well as the efforts in determining the importance or involvement of them in maize resistance through biochemical, molecular and genetics …