Digital Commons Network^™

Same-Sex Socio-Sexual Interactions Among A Group Of Captive Bottlenose Dolphins (Tursiops Truncatus), Natalia Botero Acosta

Master's Theses

Bottlenose dolphins (Tursiops truncatus) frequently engage in non-reproductive sexual behavior, including homosexual encounters. In order to better understand the nature and function of these interactions, a longitudinal study of the patterns of association and the dynamics of initiator/recipient role exchange was conducted. Underwater video footage of a colony of bottlenose dolphins housed at the Roatan Institute for Marine Sciences (RIMS), collected between March of 2010 and May of 2013, was analyzed. Associations occurring during homosexual interactions were transitory for most individuals. Nonetheless, subsequent analyses allowed the rejection of the null hypothesis of random association, suggesting the existence of …

Paleopathology At The Shady Grove Site (22qu525): A Study Of Health In The Upper Yazoo Basin During The Middle Mississippian Period, Christopher Brady Davis

Master's Theses

The Mississippian Period (AD 1000-1539) is characterized by increasingly sedentary populations, mound building, ranked societies, and intensified agriculture. As agriculture spread throughout the Eastern Woodlands, it led to widespread health consequences, including poor nutrition and increased levels of infection. Also, environmental shifts during the Mississippian Period (AD 1000-1539) caused drier conditions, potentially leading to crop failures further exacerbating nutritional problems.

This thesis focuses on the health of the Shady Grove site in the Upper Yazoo Basin, a Middle to Late Mississippian medium sized mound center where an ossuary containing up to 100 individuals was excavated in 2010. Focusing only on …

Maternal Effects And Offspring Behavior: Potential Contributors To The Lack Of Recruitment In Mississippi Gopher Tortoises (Gopherus Polyphemus), Aaron L. Holbrook

Master's Theses

Federally threatened in Mississippi, gopher tortoise (Gopherus polyphemus) populations within the state have strongly variable recruitment and are generally in decline. Hatching success is significantly lower in Mississippi than in any other part of the species’ range , and most hatchlings die within the first year. There are few refuges where survival and hatching success is high. Here I compare two populations that differ in recruitment and offspring survival for differences in corticosterone. Corticosterone is a hormone that influences both energy availability and is released in elevated levels during stressful events, like living in poor quality habitat. Prolonged corticosterone elevation …

Feeding The South: An Assessment Of Food Availability In Rural Mississippi, Nicole Baiza Lawrence

Master's Theses

The overall goal of this project is to investigate Mississippi’s rural food environment by assessing the food resources available to rural Mississippians. The primary objectives were to identify sample locations in each of the four cultural regions of Mississippi and determine the food resources available to residents of those counties. The intellectual merit of this research lies in its in-depth exploration of food accessibility in rural areas. Though there is a wealth of literature on the topics of urban food access and food deserts, very little research has been done in rural areas. Most studies focus on urban environments which …

Territorial Defense Strategies In The Northern Cardinal (Cardinalis Cardinalis): Who Is The Bigger Threat?, Kaylee M. Gentry

Master's Theses

This thesis examines the use of defensive strategies in relation to territories year round in the northern cardinal (Cardinalis cardinalis). Responses to recorded neighbor song and stranger song playback from the middle of a focal male’s territory were measured. This allowed for an estimation of aggression in both the winter and spring seasons. Each focal male was subjected to both treatments (stranger song and neighbor song). Males were more responsive over-all to neighbor song playback, however in the winter months, persistence of response to neighbor song playback increased. It was also shown that southeastern United States cardinals show …

Open Up, Mahima Tuladhar

Theses

pen up is a graduate 2D animation thesis with a run time of 6 minutes and 27 seconds. It explores the strained relationship between a boy and his father. In amidst of a fight between the two the boy run’s out of the house following a light wisp. It leads him to a cliff where a woman in a black cloak stands. She gives the boy a very magical experience and a reminder of the love he once had with his family. He goes back home where he reminds his father about the love they once had and that they …

Platform For Environmental Sensing Of Algae, Alex Wu

Electrical Engineering

No abstract provided.

Towards A Framework For Reproductive Violence”, Caitlyn Kelty-Huber

All Student Scholarship

Since the inception of ecofeminist discourse in the 1970’s, ecofeminists and feminists alike have been divided on their stances toward the ethics of consuming the bodies and by-products of other animals. A powerful cohort of ecofeminists, in part comprised by such scholars as Marti Kheel, Lori Gruen, Greta Gaard, and Carol J. Adams, have done a tremendous amount of work to situate a concern for more-than-human animals within ecofeminism and beyond. Unfortunately, as Cusack highlights, feminism’s failure to both recognize the parallel oppression of “dairy” cows and female farmed animals, and to thoughtfully incorporate that knowledge into feminist praxis has …

Hermit, Kira Gregory

Gandy Dancer Archives

No abstract provided.

Sinkhole, Sarah Steil

Gandy Dancer Archives

No abstract provided.

Racial Intolerance During The California Gold Rush, Raul David Lopez

Theses and Dissertations

The California Gold Rush started in 1848 and lasted to the mid-1850s. Though short in duration, the impact the Gold Rush had in the United States, along with populations from many areas in the rest of the world, proved detrimental to many different ethnic groups that arrived to the mines and came into contact with various cultures, principally the white Anglo-American culture. This thesis focuses on themes such as race, gender roles, free labor versus unfree labor, extra-legal violence, and informal laws passed in the mines to exclude foreigners. It addresses why certain nationalities were taxed and targeted as foes, …

Coordinated Persuasion With Dynamic Group Formation For Collaborative Elderly Care, Budhitama Subagdja, Ah-Hwee Tan

Research Collection School Of Computing and Information Systems

Ageing in place demands a new paradigm of inhouse caregiving allowing many aspects of daily lives to be tackled by smart appliances and technologies. The important challenges include the effective provision of recommendations by multiple parties of caregiver constituting changes of the user's behavior. In this multiagent environment, interdependencies between agents become major issues to tackle. This paper presents an approach of dynamic group formation for autonomous caregiving agents to collaborate in recommending different aspects of well-being. The approach supports the agents to regulate the timing of their recommendations, prevent conflicting messages, and cooperate to make more effective persuasions. A …

Investigation Of Groundwater Quality Of Al Hayer Area, (North Of Al Ain City) Using Hydro Geochemical Approach, Mohammed Hosny Ibrahim Gadalla

Theses

Al Hayer is located in the northeast of Al Ain area, Eastern region of the United Arab Emirates. Groundwater abstraction for domestic, agricultural and industrial uses has led to major depletion in the aquifer resulting in groundwater quality deterioration. This study aims to identify the factors affecting the groundwater quality in this area, and to determine the recharge mechanism for the study area to understand the behaviour of major ions in regional groundwater by using hydrogeochemical and isotopic approaches. The hydrochemical analysis of 37 collected samples of groundwater revealed that the groundwater is characterized by moderate salinity and high concentrations …

Use Of Interactive Electronic Audience Response Tools (Clickers) To Evaluate Knowledge Gained In Extension Programming, Patrick Gunn, Dan Loy

Journal of Extension

Effectively measuring short-term impact, particularly a change in knowledge resulting from Extension programming, can prove to be challenging. Clicker-based technology, when used properly, is one alternative that may allow educators to better evaluate this aspect of the logic model. While the potential interface between clicker technology and Extension programming has been a topic of discussion, the successful use and stakeholder attitude towards such technology in an Extension setting is not well known. This article addresses this gap in understanding and provides an assessment of clicker use in Extension programming.

Shared Spatial Regulating In Sharing-Economy Districts, Michael N. Widener

Seton Hall Law Review

No abstract provided.

Producer Interest In A Food Hub: A Look At Attributes, Adaptations And Attitude, Jennifer Michele Muzinic

Graduate Theses/Dissertations

Demand for locally-sourced food in the United States has spurred the introduction of a number of food hubs in recent years. The objective of this study was to examine the attitudes of agricultural producers in the Missouri Ozarks towards participation in a food hub. A survey of 218 farmers was conducted to assess how likely producers were to sell into a food hub and whether those producers would be willing to alter their supply to accommodate the needs of the proposed hub. Descriptive statistics, factor analysis and regression analysis were used to uncover which variables were most likely to contribute …

Examination Of Larval Transport, Distribution And Hybridization Patterns Of Two Blue Mussel Species Mytilus Edulis And M. Trossulus In Machias Bay, Maine, Elizabeth A. Prochaska

All Theses And Dissertations

Using an interdisciplinary approach, this study examined the population connectivity of the blue mussel Mytilus trossulus within Machias Bay, Maine, near its inshore southern boundary range. The Eastern Maine Coast Current (EMCC) flows southwestward along the northern Gulf of Maine coastline, just outside of Machias Bay and is a potential pathway for M. trossulus larvae. This study compared results to two historical studies that assayed M. trossulus and M. edulis species distributions to evaluate any temporal changes. Both similarities and differences were found in species composition in Machias Bay. Historical data suggested that the lower Machias Bay was supplied by …

The Effect Of Dietary Salt Intake On The Subcellular Distribution Of Epithelial Na+ Channels In Vasopressin And Oxytocin Synthesizing Neurons In The Rat Hypothalamus, Richard Frank Guidry

Honors Capstones

No abstract provided.

Quantitative Analysis Of The Total Bacteria, Lactobacillus, And Bifidobacterium Colonic Microflora In Rats Fed Conventional, Prebiotic, And Probiotic Soy Diets, Deborah Osterholm Jung

Theses

Research suggests that specific compositions of gut microbiota can directly affect energy harvesting and fat storage, which may indicate a potential role of intestinal bacteria in the regulation of body weight (i.e., obesity). The purpose of the current study was to determine if prebiotic- and probiotic-based diets modify gut microbiota in genetically obese rodents. For this, female Zucker diabetic fatty (ZDF) rats were assigned diets containing fructooligosaccharides (FOS), Bifidobacterium (BIF), or Lactobacillus (LAC) for three weeks. qPCR was then used to measure levels of colonic Bifidobacterium, Lactobacillus, and total bacteria. At termination, there was no significant difference in Lactobacillus levels …

Understanding Chytridiomycosis Resistance By Investigating The Cutaneous Defense Mechanisms Of Marsupial Frogs, David Burkart

Theses

Anurans are declining worldwide because of the spread of Batachochytrium dendrobatidis (Bd), the fungus that causes chytridiomycosis. However, some frogs are resistant to this disease, and understanding why may be critical to saving those that are susceptible. In Peru, Gastrotheca excubitor is resistant to chytridiomycosis while Gastrotheca nebulanastes is susceptible. Two anuran skin defenses, symbiotic bacteria and antimicrobial peptides (AMPs), have demonstrated the ability to inhibit Bd in vitro when isolated from certain frogs. We tested if these defenses can explain the difference in susceptibility between the two Gastrotheca species. The cutaneous bacteria and AMPs of both species were collected, …

Identifying Protein Kinase Tbk1 As A Novel Inhibitor Of Intestinal Tumorigenesis, Amber L. Mathews

Dissertations and Theses (Open Access)

Colorectal cancer (CRC) is the third most common cancer diagnosed in women and men， causing almost 600,000 annual deaths worldwide. There is a clear need to understand how CRC forms and progresses in order to improve the strategies of CRC prevention and therapy. A major factor that drives the development of CRC is genetic mutations that lead to activation of oncogenes and inactivation of tumor suppressor genes in intestinal epithelial cells (IECs). In addition, the initiation and progression of CRC involve environmental and immunological factors. In particular, chronic inflammatory conditions are known as an important risk factor for CRC. Intestinal …

The Role Of Dna Methylation And Hydroxymethylation In Smooth Muscle Cell Phenotypic Change During Atherogenesis, Jason Williams

Dissertations and Theses (Open Access)

Atherosclerosis is a chronic arterial disease which impacts systemically the function of organs and tissues by causing inflammation and disruption of blood supply. During atherogenesis, lipid deposits, inflammation, and cells accumulate within the walls of arteries, ultimately leading to a buildup of fatty plaques and occlusion of the arterial lumen. In a multifactorial disease like atherosclerosis there are complex interplays between environmental, genetic and epigenetic risk factors. The epigenetics of atherosclerosis involving DNA methylation has been progressing from single gene to genome wide analyses. Although these epistudies have provided evidence that DNA methylation exists within certain genes during atherogenesis, the …

Prediction Of Laser Ablation In Brain: Sensitivity, Calibration, And Validation, Samuel J. Fahrenholtz

Dissertations and Theses (Open Access)

The surgical planning of MR-guided laser induced thermal therapy (MRgLITT) stands to benefit from predictive computational modeling. The dearth of physical model parameter data leads to modeling uncertainty. This work implements a well-accepted framework with three key steps for model-building: model-parameter sensitivity analysis, model calibration, and model validation.

The sensitivity study is via generalized polynomial chaos (gPC) paired with a transient finite element (FEM) model. Uniform probability distribution functions (PDFs) capture the plausible range of values suggested by the literature for five model parameters. The five PDFs are input separately into the FEM model to gain a probabilistic sensitivity response …

In Vivo Functional Significance Of Ccat2 Long Non-Coding Rna In Myelodysplastic Syndrome, Maitri Y. Shah

Dissertations and Theses (Open Access)

Long non-coding RNAs form the largest part of the mammalian non-coding transcriptome and control gene expression at various levels including chromatin modification, transcriptional and post-transcriptional processing. Although the underlying molecular mechanisms are not yet entirely understood, lncRNAs are implicated in initiation and progression of several cancers. CCAT2 is a lncRNA that spans the highly conserved 8q24 region associated with increased risk for various cancers. CCAT2 has been shown to play an important role in inducing chromosomal instability and supporting cell proliferation and cell cycle arrest. However, a causal role of CCAT2 in initiation of tumorigenesis and the importance of G/T …

Role Of Stat3 In Human Nk Cell Functions, Prasad V. Phatarpekar

Dissertations and Theses (Open Access)

Natural Killer (NK) cells are cytotoxic lymphocytes, which play a critical role in the immune response against malignant cells and microbial infections. NK cells are equipped with activating receptors, which upon detecting ligands expressed on stressed cells induce cytolytic activity of NK cells. Stimulation of NK cell proliferation and priming of NK cytolytic capability are accomplished by cytokines, which mediate their signals mainly through JAK-STAT signaling pathway. Previously, we found that K562 cells genetically modified to express membrane bound IL-21 (mbIL-21), which predominantly activates STAT3, induce robust expansion and activation of human NK cells. Further investigations revealed role of STAT3 …

Mobilization Of Adipose Stromal Cells In Obesity And Cancer By Sparc And Its Proteolytic Isoforms, Chieh Tseng

Dissertations and Theses (Open Access)

Obesity increases cancer risk and progression as shown by epidemiologic studies. However, the underlying pathophysiology remained unclear. Adipose stromal cells (ASC) are adipose tissue-derived mesenchymal progenitors, abundant in white adipose tissue (WAT). In this study, we show that the ASC pool is expanded in obesity and is associated with promoted tumor growth. Next, by using a chimeric GFP-RFP bone marrow transplant model, we observed higher tumor infiltrating cells with ASC phenotype in obese mice compared to lean. Consistently, systemic circulating ASC frequency is six fold higher in tumor-bearing obese mice compared to lean. The tumor infiltrating cells with ASC phenotype …

Determining The Mechanisms Generating Soluble Il-15 Complexes, Scott Anthony

Dissertations and Theses (Open Access)

A diverse assortment of infectious pathogens and TLR agonists enhance the expression of Interleukin (IL)-15. Additionally, inducing lymphopenia enhances anti-tumor responses in an IL-15-dependent manner. Paradoxically, despite the limited expression of IL-15 during homeostasis, the role of IL-15 during the steady state is well-known, while its roles during inflammation and infections remain largely undefined. IL-15 uses a unique method of production and presentation to support the development and homeostasis of NK and CD8 T cells. IL-15 is produced with its high affinity IL-15Rα and this IL-15Rα/IL-15 complex is shuttled to the cell surface where it is presented in-trans or cleaved …

Normal Glycolytic Enzyme Activity Is Critical For Hypoxia Inducible Factor-1a Activity And Provides Novel Targets For Inhibiting Tumor Growth, Geoffrey Grandjean Phd

Dissertations and Theses (Open Access)

Normal Glycolytic Enzyme Activity is Critical for Hypoxia Inducible Factor-1α Activity and Provides Novel Targets for Inhibiting Tumor Growth

By Geoffrey Grandjean

Advisory Professor: Garth Powis, D. Phil

Unique to proliferating cancer cells is the observation that their increased need for energy is provided by a high rate of glycolysis followed by lactic acid fermentation in a process known as the Warburg Effect, a process many times less efficient than oxidative phosphorylation employed by normal cells to satisfy a similar energy demand ^[1]. This high rate of glycolysis occurs regardless of the concentration of oxygen in the cell and …

Molecular Regulation Of Vascular Calcification In Murine Models Of Atherosclerosis, Shanshan Gao

Dissertations and Theses (Open Access)

Background: Calcification occurs often in the atherosclerotic lesions of patients with coronary heart disease and animals with hypercholesterolemia, such as apolipoprotein-E deficient (ApoE-/-) mice. However, the mechanism(s) underlying the development of calcification in atherosclerosis remains unclear. ApoE acts as a lipid transporter, but also has been recognized as a potential regulator of osteogenesis. Little information is available as to whether ApoE has any direct impact on osteogenesis and calcification in vascular smooth muscle cells (VSMC). Several signal transduction pathways play a role in regulation of calcification, including the Wnt/β-catenin system and potentially GTAP, an ubiquitin-conjugating enzyme responsible for protein …

Effects Of Pharmacological And Genetic Disruption Of Chemokine Receptor Cxcr4 In B-Cell Acute Lymphoblastic Leukemia, Shubhchintan Randhawa

Dissertations and Theses (Open Access)

The CXCR4 chemokine receptor plays a pivotal role in homing and retention of B-cell Acute Lymphoblastic Leukemia cells to bone marrow niches. The bone marrow stromal cells (BMSCs) constitutively secrete the CXCR4 ligand CXCL12, thus attracting leukemia cells and protecting them from cytotoxic drugs, a mechanism that might be responsible for minimal residual disease after conventional chemotherapy against B-ALL. Indeed, in this study we observed that B-ALL cells that had migrated beneath the BMSCs were highly resistant to chemotherapeutic drugs. Inhibition of CXCR4 to disrupt this interaction presents itself as an attractive target to overcome bone marrow derived drug resistance …