Digital Commons Network^™

Genetic And Chemical Dissection Of Bloodbrain Barrier Development In Zebrafish, Robyn Anne Umans

Theses and Dissertations (ETD)

The blood-brain barrier (BBB) maintains a homeostatic environment as well as prohibits the entrance of xenobiotics into the brain. Because of these qualities, drug delivery is a fundamental challenge for the treatment of many diseases of the central nervous system (CNS). Along with limiting the access of therapeutics into the brain, the BBB is also impaired in CNS pathologies. Understanding the molecular cues that are essential for healthy BBB development and integrity may reveal targets for drug delivery leading to decreased progression or possible treatment of many detrimental CNS diseases. While the central features of the BBB have been accepted, …

Computer-Aided Drug Design And Discovery, Screening And Synthesis Of Small Molecule Inhibitors Of Nucleoside Transporters, Hilaire Colleen Playa

Theses and Dissertations (ETD)

Using prior biological data, pharmacophore models were made for hCNT1, hCNT3, hENT1, and hENT4. The hCNT3 and hCNT1 pharmacophore were used to select compounds for biological testing. The NBMPR analogue and dipyridamole analogue hENT1 pharmacophores were compared to each other and to a combined pharmacophore for hENT1. The dipyridamole analogue pharmacophore better predicted non-nucleoside small molecule inhibitors, and as such appears to be the better tool for aiding in the design of new small molecule inhibitors. The hCNT3 pharmacophore failed to select active compounds and as such must be redesigned. The hCNT1 pharmacophore succeeded in identifying two moderately active compounds …

Black Reflections: One Girl’S Exploration Of African-American Culture, Zoë Johnson

Senior Honors Theses

No abstract provided.

Orenda, Lauren Reeks

Senior Honors Theses

The following work is a feature length screenplay about Anna Morris, an 18-year-old girl who finds herself faced with a moral dilemma when her estranged father, Robert, contacts her on her 18th birthday. When she learns about Robert’s past involvement in an online child pornography ring Anna must decide if she can forgive him, or -- more importantly -- if he is worthy of forgiveness. However, as the story unfolds we find that it is not just Anna who needs to forgive. This story approaches issues of repentance, growth, and the journey into adulthood as Anna takes on each new …

Reference And Presupposition, Jeffrey N. Bagwell

Senior Honors Theses

The topic of this paper is the logical analysis and translation of definite descriptions (structures of the form ‘the F’), in particular Bertrand Russell’s Theory of Descriptions, as put forth in “On Denoting” (1905). I argue in favor of an opposing theory, a presuppositional analysis of definite descriptions that fits in the tradition of Frege and Strawson, building upon the recent work of Heim and Elbourne. I argue that a definite description has a referential function that is supported by presuppositions of existence and uniqueness located outside of the analyzed sentence. Using a series of example sentences, I show that …

Weeb-Con, Rachel Williams

Senior Honors Theses

One of the most important parts in the development stage of filmmaking is writing a screenplay. Weeb‐Con is a thirty‐two‐page action comedy screenplay. After an anime convention in Galveston, Texas, is forcefully taken over by armed robbers in creepy, badlymade fursuits, it is up to Dolores “Dolly” Lopez, a Lolita who must lead the convention attendees ‐ including her family and her fat pitbull Butterball ‐ and make them band together. Dolly is something of a perfectionist loner; but, with the help of her new friends Seymour, a cowardly nerd, and Boyd, a stoner who is smarter than he looks, …

Teaching Globally, Learning Locally, Dennis R. Falk, Darrell A. Hamlin

eJournal of Public Affairs

No abstract provided.

Assessing Aascu’S Global Challenges Blended Model Course, Shala Mills, Jian Sun

eJournal of Public Affairs

In 2006 the American Association of State Colleges and Universities (AASCU) launched its Global Engagement Initiative and began developing a set of curricular tools for faculty to use in educating globally competent citizens. In 2011 the initiative developed a national blended model course. That course has now been delivered to more than 1,200 students on 15 campuses across the country and abroad. This paper explores the effectiveness of the national blended course in meeting its stated learning objectives. In 2013-14, pre/post-tests were conducted on three pilot campuses. The pre/post-tests indicate that students’ knowledge about global issues and ways to get …

Modelling Storm Response On Gravel Beaches Using Xbeach-G, G Masselink, R Mccall, T Poate, Geer P Van

School of Biological and Marine Sciences

No abstract provided.

Reforming Christianity By Reforming Christians: Devotional Writings Of The Late Medieval And Reformation Era, Christopher J. Quail

History Theses

During the late medieval and Reformation era in Europe, a series of Christian devotional works were created that stressed a deeper personal relationship with Christ, rather than ritual and public devotion alone. These works span the time period from the early fifteenth century through the early seventeenth century and prepared the way for and shaped the Protestant and Roman Catholic reformations alike. The devotional works addressed here were created in the quest for reform, of both the individual and the Church. This occurred as the importance of developing a better relationship with Jesus was taking on a new urgency for …

Alumnos Transnacionales En México Y Estados Unidos. Docentes Y Los Desafíos De La Globalización, Juan Sánchez García, Edmund T. Hamann

Department of Teaching, Learning, and Teacher Education: Faculty Publications

La migración internacional es un fenómeno que se encuentra presente en el desarrollo histórico de todos los países. Un hecho reciente es la migración escolar de niños y adolescentes en el contexto de la globalización. Este estudio se enfoca en la migración de retorno o llegada por vez primera de alumnos transnacionales que tuvieron la experiencia de haber vivido y estudiado en Estados Unidos y que se encuentran en escuelas mexicanas. El propósito de este artículo es explicar los resultados de una investigación de largo plazo sobre los alumnos transnacionales. Con la aplicación de métodos mixtos a través de un …

Participatory Democracy In The Chinese Cyber World: Case Studies From Weibo, Duyi Li

Master's Theses

This thesis discusses features of citizen communication on Weibo, the Chinese social media platform, and its relationship to participatory democracy in China. Weibo is a complex social space due to the interplay of different forces and social actors. On the one hand, Weibo provides the space for bottom-up political participation: it expands the horizontal discursive space where plural discourses coexist and interact; provides a social sphere where counter-discourses are created; a space where the culture of resistance is formed; and serves as an alternative source for information. On the other hand, the vertical political control of the state, and the …

Reducing Eating Disorder Risk Factors: A Controlled Investigation Of A Blended Task-Shifting/Train-The-Trainer Approach To Dissemination And Implementation, Lisa S. Kilpela, Kaitlin Hill, Mackenzie Kelly, Joanna Elmquist, Paige Ottoson, D. Keith, Thomas Hildebrandt, Carolyn Becker

Psychology Faculty Research

Recent advances in psychological intervention research have led to an increase in evidence-based interventions (EBIs), yet there remains a lag in dissemination and implementation of EBIs. Task-shifting and the train-the-trainer (TTT) model offer two potential strategies for enhancing reach of EBIs. The Body Project, an EBI found to prevent onset of eating disorders, served as the vehicle for this dissemination/implementation study. The primary aim of this study was to determine if training of peer-leaders for the Body Project could be task-shifted to undergraduate students using a hybrid task-shifting/TTT model. Our secondary aim was to determine if subgroups of participants evidenced …

Writing & Linguistics News, Georgia Southern University

Writing & Linguistics News (2012-2022)

• Burning Swamp reading & Brannen Creative Writing Award ceremony

Las Mariposas, Fernando Ontiveros-Llamas

Verbum

No abstract provided.

Man Facing Southeast: Would We Know Jesus If We Saw Him?, Adrienne Aldridge

Verbum

In lieu of an abstract, below is the first paragraph of the essay:

Directed and written by Eliseo Subiela, Man Facing Southeast is a drama-science fiction film released in 1986. The film tells the story of a jaded, divorced Dr. Julio Denis who works at Buenos Aires’ Jose Borda Psychiatric Hospital and Rantes, a patient who mysteriously arrives and claims to come from space. The two develop a close relationship where Dr. Denis takes Rantes on several excursions and even introduces him to his children. He stands facing the southeast sending and receiving information from “home.” I initially thought he …

The Odd One, Zoe Thomas

Verbum

In lieu of an abstract, below is the essay's first paragraph:

As a child, it was routine for my family to have morning devotions where my parents would not only read passages of scriptures, but also break down verse by verse what they mean. This helped shape my spiritual life. My parents made it their duty to instill the belief of Yahweh in me. However, growing up under this strict religious background was bitter-sweet.

Faith Through The Argentine Streets, Olivia Lopez

Verbum

In lieu of an abstract, below is the essay's first paragraph:

My first exposure to the Argentine culture was one evening that I will never forget. As a sophomore at St. John Fisher College, I was blessed with the opportunity to spend a semester in Buenos Aires, Argentina with a host family. After two days of traveling, I finally made it to my destination, and moved everything into my new home. It was extremely overwhelming at first, but I quickly found my way. The second night I was in Argentina, I was invited to the house of my advisor along …

Revelations From A Dying Planet: Agriculture, Corporate Capitalism, And The Murder Of Nature, Linda Maccammon

Verbum

In lieu of an abstract, below is the essay's first paragraph:

Planet Earth is in trouble. Present and future generations are contributing to and inheriting levels of environmental degradation unparalleled in human history. Increasingly violent weather, droughts, floods, water and air pollution, species extinction and other environmental calamities are becoming commonplace. Every day we read alarming statistics and bleak forecasts about the deteriorating state of the environment and our chances of future survival, and every day there’s a new round of worry, finger-pointing, and denial. While government agencies, non-governmental organizations (NGO’s), environmental activists, and concerned citizens labor to protect and …

The Cry Of The Fisher, Tim Madigan

Verbum

In lieu of an abstract, below is the essay's first paragraph:

A few years back, while reading The New York Times as I am wont to do (I’m one of the diehards who still insists of getting a hard copy at the campus bookstore every morning) I was startled by a picture illustrating an article with the headline: “A Fierce Predator Makes a Home in the Suburbs.” Below the title was a photo of a ferocious creature attacking a bird feeder, with a diabolical expression on its face that made it look like something that came directly out of the …

It Is Better To Be Like Garry, Wes Renfro

Verbum

In lieu of an abstract, below is the essay's first paragraph:

When I was a much younger person, I had grandiose plans for myself. In the final weeks of my high school career, I participated in a scholarship competition. Members of the selection committee peppered me and a few of my classmates with questions about our future plans. After an hour of perfunctory and banal back and forth about college selection and potential courses of study, a member of the committee said, “We are having a very difficult time deciding which finalist is most deserving of the award.” The committee …

Be Famous, Joel Rivera

Verbum

In lieu of an abstract, below is the essay's first paragraph:

Everyone wants to be famous. Everyone wants to be popular and recognized, but not everyone can. Some people are really friendly and some are really shy. Popularity is literally your friend list. Some lists are larger than others, however they mean nothing. It’s one thing to have a lot of friends, but if they don’t know or care about you then they are not your friends. For example, you could have over 2,000 friends on Facebook, but if you only know 50 of them then you don’t have 2,000 …

Full Issue, No Author

Verbum

This is the full issue of Volume 12, Issue 1 of Verbum, published in Fall 2014 by the REST Club at St. John Fisher College. Articles from this issue are available as separate PDFs at http://fisherpub.sjfc.edu/verbum/vol12/iss1/

"We're Not Ready For Huck Finn": An Important Story Struggles To Be Told, Harrison Long

Faculty Articles

What happens when one controversial text meets another in performance? How do diverse audiences from rural and metropolitan areas respond to powerful yet provocative material? The Kennesaw State University Department of Theatre&Performance Studies set out to explore just that with its Frederick Douglass/Huck Finn Arts Education Initiative. The project was called Splittin' the Raft, a dramatic adaptation of Mark Twain's Adventures of Huckleberry Finn as interpreted by ex-slave and abolitionist Frederick Douglass. This ambitious production toured seven North Georgia communities, ranging from inner city schools to rural mountain towns. The production employed "epic theatre" strategies to inspire a new understanding …

Cpc Update

NASIG Newsletter

No abstract provided.

Nasig's New Mission & Vision Statement

NASIG Newsletter

No abstract provided.

Nasig’S New Partnership With The Library Publishing Coalition

NASIG Newsletter

No abstract provided.

Vision Speakers Announced For The 2015 Nasig Annual Conference

NASIG Newsletter

No abstract provided.

December 2014 Full Issue

NASIG Newsletter

No abstract provided.

Turning Labor Into Capital: Pension Funds And The Corporate Control Of Finance, Michael A. Mccarthy

Social and Cultural Sciences Faculty Research and Publications

This article explores union attempts to control pension fund investment for the debate on financial restructuring in the United States. It puts popular control of finance into comparative and historical perspective and argues that laws and politics help explain why the flow of finance is corporate controlled. First, changes in the legal regime—the Taft-Hartley Act of 1947 and the Employee Retirement Income Security Act (ERISA) of 1974—put constraints on labor’s ability to influence investment decisions. This is evident when comparing single- and multi-employer plans, where the laws had different consequences. Second, attempts to reform these laws failed. Had they been …