Digital Commons Network^™

What Does A Successful, Sustainable Telemedicine Program Look Like? An Inside View Of Six Telemedicine Programs In Maine, Edwina Ducker

Muskie School Capstones and Dissertations

The purpose of this capstone is to better understand the successes and lessons learned in the development and implementation of successful programs to help guide future decision making when planning a new program. The study relies on semi-structured interviews with Telehealth forum members and staff from a select number of telemedicine programs for its primary data source. Initially, secondary data sources and members from the Maine Telehealth Forum were used to inform the development of the list of programs to be interviewed. The programs interviewed include; a behavioral health, two specialties, a home health, a primary care, and a hospital …

Aberrant Neurogenic And Epigenetic Processes Are Associated With Depression Induced By Developmental Arsenic Exposure, Christina René Tyler

Biomedical Sciences ETDs

Arsenic is a pervasive environmental contaminant derived from both natural and anthropogenic sources. Epidemiological evidence supports a correlation between arsenic exposure in drinking water and increased rates of psychiatric disorders, including depression, in exposed populations. Previous studies have established that perinatal exposure to arsenic (through all three trimesters of fetal/neonatal development, DAE) has long-lasting consequences into adulthood including deficits in learning and memory, molecular aberrations in the hypothalamic-adrenal-pituitary (HPA) axis, and depressive-like symptoms in mice. The studies described in this dissertation were designed to assess the impact of DAE on adult hippocampal neurogenesis (AHN) as a possible mechanism of action …

The Role Of Mir-137 In Schizophrenia, Carrie Leigh Wright

Biomedical Sciences ETDs

The genetic basis of schizophrenia is still largely unknown. Recent evidence suggests that a microRNA (miRNA), miR-137 may be involved. The first large schizophrenia genome wide association (GWAS) study, published in 2011, identified a variant within the host gene of this miRNA (MIR-137) as the top association. Since then, further evidence for the potential influence of this miRNA within the disorder has accumulated. These studies used a variety of methods from GWAS to neuroimaging. However, few studies have evaluated the mechanism for the association of the MIR-137 variant, nor how alterations in the miRNA may have downstream effects on its …

Investigation Into The Early Events Of Epithelial Wound Healing And Hpv16 Infection, Michael P. Kivitz

Biomedical Sciences ETDs

HPV16 infection evidently occurs within wounded epithelial tissue, but the cellular and molecular events that culminate in infection establishment remain poorly understood. While HPV is exposed to a multitude of cells in the wound environment, only hyperproliferative keratinocytes are believed to support productive infection. Keratinocytes acquire mobility during wound repair by undergoing prominent phenotypic alterations through an epithelial-to-mesenchymal transition (EMT). In this study, cell- and tissue-based models were employed to characterize HPV infection during epithelial wound healing, using both physical injury and growth factor treatment to induce keratinocyte migration. In a tissue-based model of wounding and infection using NIKS-derived organotypic …

District 1 Climate Change Vulnerability Assessment And Pilot Studies Fhwa Climate Resilience Pilot Final Reports, Ghd, Trinity Associates, Esa Pwa

State & Federal Reports and Publications

No abstract provided.

District 1 Climate Change Vulnerability Assessment And Pilot Studies, Appendices, Ghd, Esa Pwa, Trinity Associates

State & Federal Reports and Publications

No abstract provided.

In Vivo Dosimetry Using Plastic Scintillation Detectors For External Beam Radiation Therapy, Landon S. Wootton

Dissertations and Theses (Open Access)

In vivo dosimetry, the direct measurement of dose delivered to patients during radiation therapy, has significant potential in ensuring safe and effective treatment in radiation therapy. It can serve as point-of-delivery, patient specific quality assurance and direct verification of treatment. Despite evidence that in vivo dosimetry can detect errors in patient treatment that would otherwise go undetected, it is not commonly practiced. This is due in part to a lack of available detectors ideally suited to perform in vivo dosimetry. Plastic scintillation detectors (PSDs) possess a number of dosimetric characteristics advantageous for in vivo dosimetry including water equivalence, real-time capability, …

Novel Posttranslational Modification In Lkb1 Activation And Function, Szu-Wei Lee

Dissertations and Theses (Open Access)

Cancer cells display dramatic alterations in cellular metabolism to meet their needs of increased growth and proliferation. In the last decade, cancer research has brought these pathways into focus, and one emerging issue that has come to attention is that many oncogenes and tumor-suppressors are intimately linked to metabolic regulation (Jones and Thompson, 2009). One of the key tumor-suppressors involved in metabolism is Liver Kinase B1 (LKB1). LKB1 is the major upstream kinase of the evolutionarily conserved metabolic sensor—AMP-activated protein kinase (AMPK). Activation of the LKB1/AMPK pathway provides a survival advantage for cells under energy stress. LKB1 forms a heterotrimeric …

Clemson Trustees Minutes, 2014 December 1, Clemson University Board Of Trustees

Minutes

No abstract provided.

Insulin Resistance And Muscle Insulin Receptor Substrate-1 Serine Hyperphosphorylation, Charles A. Stuart, Mary E. A. Howell, Brian M. Cartwright, Melanie P. Mccurry, Michelle L. Lee, Michael W. Ramsey, Michael H. Stone

ETSU Faculty Works

Insulin resistance in metabolic syndrome subjects is profound in spite of muscle insulin receptor and insulin-responsive glucose transporter (GLUT4) expression being nearly normal. Insulin receptor tyrosine kinase phosphorylation of insulin receptor substrate-1 (IRS-1) at Tyr896 is a necessary step in insulin stimulation of translocation of GLUT4 to the cell surface. Serine phosphorylation of IRS-1 by some kinases diminishes insulin action in mice. We evaluated the phosphorylation status of muscle IRS-1 in 33 subjects with the metabolic syndrome and seventeen lean controls. Each underwent euglycemic insulin clamps and a thigh muscle biopsy before and after 8 weeks of either strength or …

An Exploratory Study On The Use Of Concentric Velocities In The Back Squat As A Monitoring Tool, Kevin M. Carroll, Josh D. Christovich, Caleb D. Bazyler, Nicholas J. Fiolo, George K. Beckham, Kimitake Sato

ETSU Faculty Works

Abstract available in the 9th Annual Coaches and Sport Science College .

Religion, Conscience, And The Case For Accommodation, William A. Galston

San Diego Law Review

I do not believe that religion is an obsolete constitutional category. But I do believe that the holdings in United States v. Seeger and Welsh v. United States, the Vietnam-era draft cases that extended conscientious objector status to individuals invoking nonreligious claims, were correct. Can I consistently embrace both propositions? I think I can. My argument, in brief, is that religion is indeed special. But when we understand what it is about religion that warrants both distinctive privileges and distinctive burdens, we will see that some other systems of belief track these features of religion closely enough to warrant comparable …

Lady Gaga: Performer, Persona, And Political Advocate, Cassidy Burns

Communication Studies

No abstract provided.

The Mechanism Of Lhcp Insertion Into Thylakoid Membranes, Larae Brown

Graduate Theses and Dissertations

The light harvesting chlorophyll a/b-binding proteins (LHCPs) are the most abundant membrane proteins. LHCP is a nuclear encoded protein which is targeted to the thylakoid membranes by chloroplast signal recognition particles (cpSRP). Insertion into thylakoid membranes is facilitated by the cpSRP receptor cpFtsY and the Alb3 translocase. Work here focused on understanding the molecular events of LHCP insertion into the thylakoid membranes. Specifically, we sought to develop a tool to detect the insertion of the lumen-localized loop of LHCP into thylakoid membranes, which relies on cleavage of the loop by a thylakoid lumen processing protease. We also sought to understand …

Perceived Mother And Father Acceptance-Rejection Predict Four Unique Aspects Of Child Adjustment Across Nine Countries, Diane L. Putnick, Marc H. Bornstein, Jennifer E. Lansford, Patrick S. Malone, Concetta Pastorelli, Ann T. Skinner, Emma Sorbring, Sombat Tapanya, Liliana Maria Uribe Tirado, Arnaldo Zelli, Liane Peña Alampay, Suha M. Al-Hassan, Dario Bacchini, Anna Silvia Bombi, Lei Chang, Kirby Deater-Deckard, Laura Di Giunta, Kenneth A. Dodge, Paul Oburu

Psychology Department Faculty Publications

Background

It is generally believed that parental rejection of children leads to child maladaptation. However, the specific effects of perceived parental acceptance-rejection on diverse domains of child adjustment and development have been incompletely documented, and whether these effects hold across diverse populations and for mothers and fathers are still open questions.

Methods

This study assessed children's perceptions of mother and father acceptance-rejection in 1247 families from China, Colombia, Italy, Jordan, Kenya, the Philippines, Sweden, Thailand, and the United States as antecedent predictors of later internalizing and externalizing behavior problems, school performance, prosocial behavior, and social competence.

Results

Higher perceived parental …

Teacher Internship Report- Ceres High School, Michael L. Patterson

Agricultural Education: Graduate Internship Reports

This internship/project report includes validation documents required in meeting the quality criteria for secondary-level programs of instruction in agriculture. The documents are concurrently used for the Agriculture Incentive Grant review process at Ceres High School conducted by representatives of the California Department of Education. The internship included the development of a comprehensive program plan for Ceres High School. The plan includes information to receive state/local funding, outline the goals and objectives of the program, along with an overview of Ceres High School, the agriculture program and community.

Striping Truck Utilization At Crawfordsville And Greenfield, Jon Padfield, Jim Handy, Ted Boehm

JTRP Technical Reports

At the time this project was launched, INDOT was operating two paint trucks per district (one edge line truck and one center line truck). This project was launched to determine the feasibility of painting all the lane miles in each district with a single paint truck per district.

The Greenfield and Crawfordsville districts were chosen to develop and test ideas to enable the transition to painting with just one truck per district. Teams from both districts including paint truck drivers, painters and managers participated in a series of Value Stream Mapping (VSM) sessions facilitated by Purdue Technical Assistance Program (TAP). …

Increasing Bridge Deck Service Life: Volume Ii—Economic Evaluation, Samuel Labi, Robert J. Frosch, Ashish Samdariya, Qing Ye

JTRP Technical Reports

Deterioration of bridge decks is a primary factor limiting the lifespan of bridges especially in cold climates where deicing salts are commonly used. While controlling deck cracking or decreasing the permeability and porosity of concrete can improve performance and service life, chloride and moisture ingress as well as cracking cannot be eliminated. Full-depth cracks which are caused by restrained shrinkage allow for corrosive conditions at early ages for both the top and bottom reinforcement mats. Therefore, the use of corrosion-resistant reinforcement is essential to mitigate deterioration of bridge decks. The objective of this research program to examine the efficacy of …

Impact Of Hb-1481 On Indiana’S Highway Revenue Generation, Asset Degradation, Modal Distribution, And Economic Development And Competitiveness, Stephanie R. Everett, Nathee Athigakunagorn, Wubeshet Woldemariam, Vinay Varadarajan, Mohammad Arman, Arash M. Roshandeh, Konstantina Gkritza, Samuel Labi, Kumares C. Sinha

JTRP Technical Reports

The Indiana House Enrolled Act 1481 (HEA-1481) requires that the Indiana Department of Transportation (INDOT) adopt final rules by December 31, 2014, for the issuance, fee structure and enforcement of permits for overweight divisible loads, fee structure of permits for loads on extra heavy duty highways, and fee structure of permits for overweight loads. On December 26, 2013, INDOT adopted the Emergency Rules regarding these items, as required by HEA-1481, effective January 1, 2014. HEA-1481 requires INDOT to use the results of this impact study to inform the setting of final rules. Three different fee structures were considered: Pre-HEA-1481 fee …

Increasing Bridge Deck Service Life: Volume I—Technical Evaluation, Robert J. Frosch, Samuel Labi, Chungwook Sim

JTRP Technical Reports

Deterioration of bridge decks is a primary factor limiting the lifespan of bridges especially in cold climates where deicing salts are commonly used. While controlling deck cracking or decreasing the permeability and porosity of concrete can improve performance and service life, chloride and moisture ingress as well as cracking cannot be eliminated. Full-depth cracks which are caused by restrained shrinkage allow for corrosive conditions at early ages for both the top and bottom reinforcement mats. Therefore, the use of corrosion-resistant reinforcement is essential to mitigate deterioration of bridge decks. The objective of this research program to examine the efficacy of …

Improving Community Case Management Of Diarrhoea And Pneumonia In District Badin, Pakistan Through A Cluster Randomised Study--The Nigraan Trial Protocol, Fauziah Rabbani, Aftab A. Ali Mukhi, Shagufta Perveen, Xaher Gul, Saleem Iqbal Perwaiz, Shamim Ahmed Qazi, Iqbal Azam Syed, Khalid Hussain Shaikh, Wafa Aftab

Community Health Sciences

BACKGROUND:

Diarrhoea and pneumonia contribute 30% of deaths in children under 5 in Pakistan. Pakistan's Lady Health Workers Programme (LHW-P) covers about 60% of the population but has had little impact in reducing morbidity and mortality related to these major childhood killers. An external evaluation of the LHW-P suggests that lack of supportive supervision of LHWs by lady health supervisors (LHSs) is a key determinant of this problem. Project NIGRAAN aims to improve knowledge and skills of LHWs and community caregivers through supervisory strategies employed by LHSs. Ultimately, community casemanagement (CCM) of childhood pneumonia and diarrhoea will improve.

METHODS/DESIGN:

NIGRAAN …

Why The Adult Brain Likes Pla, Catherine Marienau

SCPS Competency-based Education Publications and Presentations

No abstract provided.

Garnets In Glass, David Schelhaas

Pro Rege

No abstract provided.

Missouri Puzzle, Matt Drissell

Pro Rege

No abstract provided.

Primo, Jake Van Wyk

Pro Rege

No abstract provided.

The Heterogeneous Impact Of Corporate Social Responsibility Activities That Target Different Stakeholders, Kiyoung Chang, Incheol Kim, Ying Li

Finance Faculty Publications

We aggregate different dimensions of corporate social responsibility (CSR) activities following the stakeholder framework proposed in Clarkson (Acad Manag Rev 20(1), 92–117, 1995) and present consistent evidence that CSR strengths targeting different stakeholders have their unique impact on firm risk and financial performance. Institutional CSR activities that target secondary stakeholders are negatively associated with firm risk, measured by total risk and systematic risk. Technical CSR that target primary stakeholders are positively associated with firm financial performance, measured by Tobin’s Q, ROA, and cash flow returns. Our results, based on a sample of S&P 500 component firms over the …

Truckload Shipment Planning And Procurement, Neo Nguyen

Graduate Theses and Dissertations

This dissertation presents three issues encountered by a shipper in the context of truckload transportation. In all of the studies, we utilize optimization techniques to model and solve the problems. Each study is inspired from the real world and much of the data used in the experiments is real data or representative of real data.

The first topic is about the freight consolidation in truckload transportation. We integrate it with a purchase incentive program to increase truckload utilization and maximize profit. The second topic is about supporting decision making collaboration among departments of a manufacturer. It is a bi-objective optimization …

Reconciliation Ecology: A New Paradigm For Advancing Creation Care, Dave P. Warners, Michael Ryskamp, Randall Van Dragt

University Faculty Publications and Creative Works

Current global environmental challenges—species loss, overconsumption, climate change, and others—have not been countered in the faith community with a response worthy of their signifi cance. While the prevailing faith-based creation-care paradigm, environmental stewardship, has been invaluable in moving us beyond the utilitarian notion of “dominion,” the stewardship concept does not suffi ciently emphasize our embedded, dependent relationship with the creation. To better represent our creationcare responsibilities, we propose a new paradigm based on a model of servanthood and informed by the concept of reconciliation ecology, which focuses on mending broken relationships between human beings and nonhuman creation. Drawing from the …

Strategic Planning Tool Development Using Portfolio Decision Analysis, Luis B. Vargas Rojas

Graduate Theses and Dissertations

A portfolio decision analysis strategic planning tool was developed for the Facilities Management Office at the University of Arkansas. The tool provides information to support budget allocation decisions based on their Strategic Planning Project List, project attributes (e.g, seat utilization, scheduling preferences, and sustainability rank), and budget constraints. The projects are evaluated using multiobjective decision analysis. We introduce dynamic value functions, which vary the range of the value measures based on the planning horizon, to evaluate the projects). We determine facilities portfolios based on the project values and constraints using Linear Programming. In addition, insightful reports are generated, which provide …

The Social Effect The Law Had On Prostitutes In Ancient Rome, Lauren Weisner

Grand Valley Journal of History

Prostitution was popular and common in Ancient Rome. Although Ancient Romans frequented brothels, early laws put into place by the Republic treated prostitutes as lowly individuals which caused the people of Rome to view them negatively. Eventually, the Republic changed the laws and consequently the views on prostitutes. Later laws essentially legitimized prostitution by allowing them to avoid fines for illicit sexual activities and eventually placed a tax on prostitution much like that on the regular businesses of the time. These shifts in the way prostitutes were treated legally allowed for a large shift in public perception of them as …