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2014

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An Evaluation Of Soil Extracellular Enzyme Activity In Response To Burning As A Forest Restoration Technique, William M. Steward Jan 2014

An Evaluation Of Soil Extracellular Enzyme Activity In Response To Burning As A Forest Restoration Technique, William M. Steward

Honors Theses

Burning is a method of forest restoration with the goal of returning natural tree species to ecosystems. Burning has a wide range of effects on an ecosystem, including the alteration of important soil processes and characteristics. One of the key components of soil is the activity of extracellular enzymes, which can be used to provide insight into the nutritional requirements of soil microbes as well as nutrient availability and cycling. Because enzymes are important in the overall functioning of soil and can be used to assess soil health, there is great need to examine the effects of burning on soil …


The Tutte Polynomial Formula For The Class Of Twisted Wheel Graphs, Amanda Hall Jan 2014

The Tutte Polynomial Formula For The Class Of Twisted Wheel Graphs, Amanda Hall

Honors Theses

The 20th century work of William T. Tutte developed a graph polynomial that is modernly known as the Tutte polynomial. Graph polynomials, such as the Tutte polynomial, the chromatic polynomial, and the Jones polynomial, are at the heart of combinatorical and algebraic graph theory and can be used as tools with which to study graph invariants. Graph invariants, such as order, degree, size, and connectivity which are defined in Section 2, are graph properties preserved under all isomorphisms of a graph. Thus any graph polynomial is not dependent upon a particular labeling or drawing but presents relevant information about the …


Noninvasive Imaging Of Focal Atherosclerotic Lesions Using Fluorescence Molecular Tomography, Dolonchampa Maji, Metasebya Solomon, Annie Nguyen, Richard A. Pierce, Pamela K. Woodard, Walter J. Akers, Samuel Achilefu, Joseph P. Culver, Dana R. Abendschein, Monica Shokeen Jan 2014

Noninvasive Imaging Of Focal Atherosclerotic Lesions Using Fluorescence Molecular Tomography, Dolonchampa Maji, Metasebya Solomon, Annie Nguyen, Richard A. Pierce, Pamela K. Woodard, Walter J. Akers, Samuel Achilefu, Joseph P. Culver, Dana R. Abendschein, Monica Shokeen

Open Access Publications

No abstract provided.


Nephrotic Syndrome In Acute Promyelocytic Leukemia, Borhan Moradveisi, Armin Rashidi, Samin Alavi, Alireza Eskandarifar Jan 2014

Nephrotic Syndrome In Acute Promyelocytic Leukemia, Borhan Moradveisi, Armin Rashidi, Samin Alavi, Alireza Eskandarifar

Open Access Publications

No abstract provided.


Neuronal Activity Regulates Extracellular Tau In Vivo, Kaoru Yamada, Jerrah K. Holth, Fan Liao, Floy R. Stewart, Thomas E. Mahan, Hong Jiang, John R. Cirrito, Tirth K. Patel, Katja Hochgräfe, Eva-Maria Mandelkow, David M. Holtzman Jan 2014

Neuronal Activity Regulates Extracellular Tau In Vivo, Kaoru Yamada, Jerrah K. Holth, Fan Liao, Floy R. Stewart, Thomas E. Mahan, Hong Jiang, John R. Cirrito, Tirth K. Patel, Katja Hochgräfe, Eva-Maria Mandelkow, David M. Holtzman

Open Access Publications

Tau is primarily a cytoplasmic protein that stabilizes microtubules. However, it is also found in the extracellular space of the brain at appreciable concentrations. Although its presence there may be relevant to the intercellular spread of tau pathology, the cellular mechanisms regulating tau release into the extracellular space are not well understood. To test this in the context of neuronal networks in vivo, we used in vivo microdialysis. Increasing neuronal activity rapidly increased the steady-state levels of extracellular tau in vivo. Importantly, presynaptic glutamate release is sufficient to drive tau release. Although tau release occurred within hours in response to …


Potential Role Of Orexin And Sleep Modulation In The Pathogenesis Of Alzheimer's Disease, Jee Hoon Roh, Hong Jiang, Mary Beth Finn, Floy R. Stewart, Thomas E. Mahan, John R. Cirrito, Ashish Heda, B. Joy Snider, Mingjie Li, Masashi Yanagisawa, Luis De Lecea, David M. Holtzman Jan 2014

Potential Role Of Orexin And Sleep Modulation In The Pathogenesis Of Alzheimer's Disease, Jee Hoon Roh, Hong Jiang, Mary Beth Finn, Floy R. Stewart, Thomas E. Mahan, John R. Cirrito, Ashish Heda, B. Joy Snider, Mingjie Li, Masashi Yanagisawa, Luis De Lecea, David M. Holtzman

Open Access Publications

Age-related aggregation of amyloid-β (Aβ) is an upstream pathological event in Alzheimer's disease (AD) pathogenesis, and it disrupts the sleep-wake cycle. The amount of sleep declines with aging and to a greater extent in AD. Poor sleep quality and insufficient amounts of sleep have been noted in humans with preclinical evidence of AD. However, how the amount and quality of sleep affects Aβ aggregation is not yet well understood. Orexins (hypocretins) initiate and maintain wakefulness, and loss of orexin-producing neurons causes narcolepsy. We tried to determine whether orexin release or secondary changes in sleep via orexin modulation affect Aβ pathology. …


Endothelial Cells Use Dynamic Actin To Facilitate Lymphocyte Transendothelial Migration And Maintain The Monolayer Barrier, Olivia L. Mooren, Jinmei Li, Julie Nawas, John A. Cooper Jan 2014

Endothelial Cells Use Dynamic Actin To Facilitate Lymphocyte Transendothelial Migration And Maintain The Monolayer Barrier, Olivia L. Mooren, Jinmei Li, Julie Nawas, John A. Cooper

Open Access Publications

No abstract provided.


High-Coverage Sequencing And Annotated Assemblies Of The Budgerigar Genome, Ganeshkumar Ganapathy, Wesley C. Warren, Et Al Jan 2014

High-Coverage Sequencing And Annotated Assemblies Of The Budgerigar Genome, Ganeshkumar Ganapathy, Wesley C. Warren, Et Al

Open Access Publications

No abstract provided.


A Central Support System Can Facilitate Implementation And Sustainability Of A Classroom-Based Undergraduate Research Experience (Cure) In Genomics, David Lopatto, Jeremy Buhler, Elaine Mardis, Wilson Leung, Christopher D. Shaffer, Jennifer Threlfall, Et Al Jan 2014

A Central Support System Can Facilitate Implementation And Sustainability Of A Classroom-Based Undergraduate Research Experience (Cure) In Genomics, David Lopatto, Jeremy Buhler, Elaine Mardis, Wilson Leung, Christopher D. Shaffer, Jennifer Threlfall, Et Al

Open Access Publications

No abstract provided.


Treatment Of Metastatic Spinal Lesions With A Navigational Bipolar Radiofrequency Ablation Device: A Multicenter Retrospective Study, Praveen R. Anchala, Winston D. Irving, Travis J. Hillen, Michael V. Friedman, Bassem A. Georgy, Douglass M. Coldwell, Nam D. Tran, Frank D. Vrionis, Allan Brook, Jack W. Jennings Jan 2014

Treatment Of Metastatic Spinal Lesions With A Navigational Bipolar Radiofrequency Ablation Device: A Multicenter Retrospective Study, Praveen R. Anchala, Winston D. Irving, Travis J. Hillen, Michael V. Friedman, Bassem A. Georgy, Douglass M. Coldwell, Nam D. Tran, Frank D. Vrionis, Allan Brook, Jack W. Jennings

Open Access Publications

No abstract provided.


The Cavefish Genome Reveals Candidate Genes For Eye Loss, Suzanne E. Mcgaugh, Patrick Minx, Wesley C. Warren, Et Al Jan 2014

The Cavefish Genome Reveals Candidate Genes For Eye Loss, Suzanne E. Mcgaugh, Patrick Minx, Wesley C. Warren, Et Al

Open Access Publications

No abstract provided.


Integrated Analysis Of Germline And Somatic Variants In Ovarian Cancer, Krishna L. Kanchi, Kimberly J. Johnson, Charles Lu, Michael D. Mclellan, Michael C. Wendl, Qunyuan Zhang, Daniel C. Koboldt, Mingchao Xie, Cyriac Kandoth, Joshua F. Mcmichael, Matthew A. Wyczalkowski, David E. Larson, Heather K. Schmidt, Christopher A. Miller, Robert S. Fulton, Elaine R. Mardis, Todd E. Druley, Timothy A. Graubert, Richard K. Wilson, Li Ding, Et Al Jan 2014

Integrated Analysis Of Germline And Somatic Variants In Ovarian Cancer, Krishna L. Kanchi, Kimberly J. Johnson, Charles Lu, Michael D. Mclellan, Michael C. Wendl, Qunyuan Zhang, Daniel C. Koboldt, Mingchao Xie, Cyriac Kandoth, Joshua F. Mcmichael, Matthew A. Wyczalkowski, David E. Larson, Heather K. Schmidt, Christopher A. Miller, Robert S. Fulton, Elaine R. Mardis, Todd E. Druley, Timothy A. Graubert, Richard K. Wilson, Li Ding, Et Al

Open Access Publications

No abstract provided.


Secondhand Smoke Exposure And Severity Of Attention-Deficit/Hyperactivity Disorder In Preschoolers: A Pilot Investigation, Mini Tandon, Christina N. Lessov-Schlaggar, Rebecca Tillman, Melbourne F. Hovell, Joan Luby Jan 2014

Secondhand Smoke Exposure And Severity Of Attention-Deficit/Hyperactivity Disorder In Preschoolers: A Pilot Investigation, Mini Tandon, Christina N. Lessov-Schlaggar, Rebecca Tillman, Melbourne F. Hovell, Joan Luby

Open Access Publications

No abstract provided.


Patents At Issue: The Data Behind The Patent Troll Debate, Jonathan H. Ashtor, Michael J. Mazzeo, Samantha Zyontz Jan 2014

Patents At Issue: The Data Behind The Patent Troll Debate, Jonathan H. Ashtor, Michael J. Mazzeo, Samantha Zyontz

Faculty Scholarship

The debate over "patent trolls"' is raging at full tilt and its fury is stoked by fundamental questions about patent assertion. Both sides are struggling to understand which patent assertion practices are consistent with the purpose of patent rights and which are abusive and result in net social costs. This Article addresses patent assertion concretely through empirical analysis of actual infringement awards. In particular, this Article studies all awards granted for findings of patent infringement in U.S. district courts between 1995 and 2011, and, with targeted analyses, focuses on cases involving patent assertion entities ("PAEs"). This Article specifically investigates certain …


Genome-Wide Mapping Of The Distribution Of Card, Rnap Σa, And Rnap Β On The Mycobacterium Smegmatis Chromosome Using Chromatin Immunoprecipitation Sequencing, Robert Landick, Azra Krek, Michael S. Glickman, Nicholas D. Socci, Christina L. Stallings Jan 2014

Genome-Wide Mapping Of The Distribution Of Card, Rnap Σa, And Rnap Β On The Mycobacterium Smegmatis Chromosome Using Chromatin Immunoprecipitation Sequencing, Robert Landick, Azra Krek, Michael S. Glickman, Nicholas D. Socci, Christina L. Stallings

Open Access Publications

No abstract provided.


Illustrated Techniques For Performing The Cox-Maze Iv Procedure Through A Right Mini-Thoracotomy, Jason O. Robertson, Lindsey L. Saint, Jeremy E. Leidenfrost, Ralph J. Damiano Jr. Jan 2014

Illustrated Techniques For Performing The Cox-Maze Iv Procedure Through A Right Mini-Thoracotomy, Jason O. Robertson, Lindsey L. Saint, Jeremy E. Leidenfrost, Ralph J. Damiano Jr.

Open Access Publications

No abstract provided.


Cell Type-Specific Expression Analysis To Identify Putative Cellular Mechanisms For Neurogenetic Disorders, Xiaoxiao Xu, Alan B. Wells, David R. O'Brien, Arye Nehorai, Joseph D. Dougherty Jan 2014

Cell Type-Specific Expression Analysis To Identify Putative Cellular Mechanisms For Neurogenetic Disorders, Xiaoxiao Xu, Alan B. Wells, David R. O'Brien, Arye Nehorai, Joseph D. Dougherty

Open Access Publications

No abstract provided.


An Improved Predictive Recognition Model For Cys2-His2 Zinc Finger Proteins, Ankit Gupta, Ryan G. Christensen, Heather A. Bell, Mathew Goodwin, Ronak Y. Patel, Manishi Pandey, Metewo Selase Enuameh, Amy L. Rayla, Cong Zhu, Stacey Thibodeau-Beganny, Michael H. Brodsky, J Keith Joung, Scot A. Wolfe, Gary D. Stormo Jan 2014

An Improved Predictive Recognition Model For Cys2-His2 Zinc Finger Proteins, Ankit Gupta, Ryan G. Christensen, Heather A. Bell, Mathew Goodwin, Ronak Y. Patel, Manishi Pandey, Metewo Selase Enuameh, Amy L. Rayla, Cong Zhu, Stacey Thibodeau-Beganny, Michael H. Brodsky, J Keith Joung, Scot A. Wolfe, Gary D. Stormo

Open Access Publications

No abstract provided.


Comparison Of The Stand-Alone Cox-Maze Iv Procedure To The Concomitant Cox-Maze Iv And Mitral Valve Procedure For Atrial Fibrillation, Christopher P. Lawrance, Matthew C. Henn, Jacob R. Miller, Laurie A. Sinn, Richard B. Schuessler, Ralph J. Damiano Jr. Jan 2014

Comparison Of The Stand-Alone Cox-Maze Iv Procedure To The Concomitant Cox-Maze Iv And Mitral Valve Procedure For Atrial Fibrillation, Christopher P. Lawrance, Matthew C. Henn, Jacob R. Miller, Laurie A. Sinn, Richard B. Schuessler, Ralph J. Damiano Jr.

Open Access Publications

No abstract provided.


The Semiotics Of Film In Us Supreme Court Cases, Jessica Silbey, Meghan Hayes Slack Jan 2014

The Semiotics Of Film In Us Supreme Court Cases, Jessica Silbey, Meghan Hayes Slack

Faculty Scholarship

This chapter explores the treatment of film as a cultural object among varied legal subject matter in US Supreme Court jurisprudence. Film is significant as an object or industry well beyond its incarnation as popular media. Its role in law – even the highest level of US appellate law – is similarly varied and goes well beyond the subject of a copyright case (as a moving picture) or as an evidentiary proffer (as a video of a criminal confession). This chapter traces the discussion of film in US Supreme Court cases in order to map the wide-ranging and diverse ­relations …


Hippocampal Long-Term Potentiation Is Disrupted During Expression And Extinction But Is Restored After Reinstatement Of Morphine Place Preference, George S. Portugal, Ream Al-Hasani, Amanda K. Fakira, Jose L. Gonzalez-Romero, Zare Melyan, Jordan G. Mccall, Michael R. Bruchas, Jose A. Moron Jan 2014

Hippocampal Long-Term Potentiation Is Disrupted During Expression And Extinction But Is Restored After Reinstatement Of Morphine Place Preference, George S. Portugal, Ream Al-Hasani, Amanda K. Fakira, Jose L. Gonzalez-Romero, Zare Melyan, Jordan G. Mccall, Michael R. Bruchas, Jose A. Moron

Open Access Publications

No abstract provided.


Electronic Health Record: Integrating Evidence-Based Information At The Point Of Clinical Decision Making, Susan A. Fowler, Lauren H. Yaeger, Feliciano Yu, Dwight Doerhoff, Paul Schoening Jan 2014

Electronic Health Record: Integrating Evidence-Based Information At The Point Of Clinical Decision Making, Susan A. Fowler, Lauren H. Yaeger, Feliciano Yu, Dwight Doerhoff, Paul Schoening

Open Access Publications

No abstract provided.


Whole-Genome Sequencing Of Salmonella Enterica Subsp. Enterica Serovar Cubana Strains Isolated From Agricultural Sources, George Weinstock, Et Al Jan 2014

Whole-Genome Sequencing Of Salmonella Enterica Subsp. Enterica Serovar Cubana Strains Isolated From Agricultural Sources, George Weinstock, Et Al

Open Access Publications

No abstract provided.


Targeting The Programmed Cell Death 1: Programmed Cell Death Ligand 1 Pathway Reverses T Cell Exhaustion In Patients With Sepsis, Katherine Chang, Catherine Svabek, Cristina Vazquez-Guillamet, Bryan Sato, David Rasche, Strother Wilson, Paul Robbins, Nancy Ulbrandt, Joann Suzich, Jonathan Green, Andriani C. Patera, Wade Blair, Subramaniam Krishnan, Richard Hotchkiss Jan 2014

Targeting The Programmed Cell Death 1: Programmed Cell Death Ligand 1 Pathway Reverses T Cell Exhaustion In Patients With Sepsis, Katherine Chang, Catherine Svabek, Cristina Vazquez-Guillamet, Bryan Sato, David Rasche, Strother Wilson, Paul Robbins, Nancy Ulbrandt, Joann Suzich, Jonathan Green, Andriani C. Patera, Wade Blair, Subramaniam Krishnan, Richard Hotchkiss

Open Access Publications

No abstract provided.


Tax Inflicts Dna Damage Through Activation Of Nitric Oxide Production, Hicham H. Baydoun, Lee Ratner Jan 2014

Tax Inflicts Dna Damage Through Activation Of Nitric Oxide Production, Hicham H. Baydoun, Lee Ratner

Open Access Publications

No abstract provided.


Economic Evaluation Of Access To Musculoskeletal Care: The Case Of Waiting For Total Knee Arthroplasty, Richard C. Mather Iii, Kevin T. Hug, Lori A. Orlando, Tyler Steven Watters, Lane Koenig, Ryan M. Nunley, Michael P. Bolognesi Jan 2014

Economic Evaluation Of Access To Musculoskeletal Care: The Case Of Waiting For Total Knee Arthroplasty, Richard C. Mather Iii, Kevin T. Hug, Lori A. Orlando, Tyler Steven Watters, Lane Koenig, Ryan M. Nunley, Michael P. Bolognesi

Open Access Publications

No abstract provided.


Novel Treatment Option For Muc16-Positive Malignancies With The Targeted Trail-Based Fusion Protein Meso-Tr3, Gunjal Garg, Jesse Gibbs, Brian Belt, Matthew A. Powell, David G. Mutch, Peter Goedegebuure, Lynne Collins, David Piwnica-Worms, William G. Hawkins, Dirk Spitzer Jan 2014

Novel Treatment Option For Muc16-Positive Malignancies With The Targeted Trail-Based Fusion Protein Meso-Tr3, Gunjal Garg, Jesse Gibbs, Brian Belt, Matthew A. Powell, David G. Mutch, Peter Goedegebuure, Lynne Collins, David Piwnica-Worms, William G. Hawkins, Dirk Spitzer

Open Access Publications

No abstract provided.


A Cross-Sectional Study Of Differences In 6-Min Walk Distance In Healthy Adults Residing At High Altitude Versus Sea Level, Deirdre Caffrey, J. Jaime Miranda, Robert H. Gilman, Victor G. Davila-Roman, Lilia Cabrera, Russell Dowling, Talia Stewart, Antonio Bernabe-Ortiz, Robert Wise, Fabiola Leon-Velarde, William Checkley, Cronicas Cohort Study Group Jan 2014

A Cross-Sectional Study Of Differences In 6-Min Walk Distance In Healthy Adults Residing At High Altitude Versus Sea Level, Deirdre Caffrey, J. Jaime Miranda, Robert H. Gilman, Victor G. Davila-Roman, Lilia Cabrera, Russell Dowling, Talia Stewart, Antonio Bernabe-Ortiz, Robert Wise, Fabiola Leon-Velarde, William Checkley, Cronicas Cohort Study Group

Open Access Publications

No abstract provided.


The Bacterial Amyloid Curli Is Associated With Urinary Source Bloodstream Infection, Chia Hung, Jonas Marschall, Carey-Ann D. Burnham, Albert S. Byun, Jeffrey P. Henderson Jan 2014

The Bacterial Amyloid Curli Is Associated With Urinary Source Bloodstream Infection, Chia Hung, Jonas Marschall, Carey-Ann D. Burnham, Albert S. Byun, Jeffrey P. Henderson

Open Access Publications

No abstract provided.


Regulation Of The Hsp104 Middle Domain Activity Is Critical For Yeast Prion Propagation, Jennifer E. Dulle, Kevin C. Stein, Heather L. True Jan 2014

Regulation Of The Hsp104 Middle Domain Activity Is Critical For Yeast Prion Propagation, Jennifer E. Dulle, Kevin C. Stein, Heather L. True

Open Access Publications

No abstract provided.