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2014

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Articles 133051 - 133080 of 135667

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Protective Roles Of Cimin Grape Tissues On Oxidative Stress Markers In The Cellular System Model, Hüseyi̇n Avni̇ Uydu, Ari̇fe Pinar Eki̇nci̇, Mehtap Atak, Adem Demi̇r Jan 2014

Protective Roles Of Cimin Grape Tissues On Oxidative Stress Markers In The Cellular System Model, Hüseyi̇n Avni̇ Uydu, Ari̇fe Pinar Eki̇nci̇, Mehtap Atak, Adem Demi̇r

Turkish Journal of Medical Sciences

To analyze the phenolic composition of the Cimin grape, which is 1 of 2 grape varieties with a protected geographical indication in Turkey and is used locally to treat the symptoms of some disorders such as impotence and cardiovascular diseases, and to investigate its antioxidant potency against oxidant mediators in the models of intra- and extracellular surroundings. Materials and methods: Cimin grape samples were classified into 5 groups according to the grape's tissues and the extraction solvents used. Free radical scavenging (DPPH) and antilipid peroxidation product [thiobarbituric acid reactive substance (TBARS) and conjugated diene (CD)] levels of the grape tissues …

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Liver Enzymes, Mean Platelet Volume, And Red Cell Distribution Width In Gestational Diabetes, Serpi̇l Erdoğan, Özhan Özdemi̇r, Halef Okan Doğan, Sevi̇lay Sezer, Cemal Reşat Atalay, Fatma Meri̇ç Yilmaz, Yüksel Koca Jan 2014

Liver Enzymes, Mean Platelet Volume, And Red Cell Distribution Width In Gestational Diabetes, Serpi̇l Erdoğan, Özhan Özdemi̇r, Halef Okan Doğan, Sevi̇lay Sezer, Cemal Reşat Atalay, Fatma Meri̇ç Yilmaz, Yüksel Koca

Turkish Journal of Medical Sciences

To investigate the value of measuring liver enzymes, red cell distribution width (RDW), and mean platelet volume (MPV) in predicting the development of gestational diabetes mellitus (GDM). Materials and methods: The medical records of all pregnant women followed by the obstetrics clinic between January 2010 and November 2012 were systematically evaluated, and patients with a diagnosis of GDM were identified. A total of 68 patients with GDM and 61 healthy controls were included in the study. Results of relevant laboratory parameters were recorded. Results: Out of all the parameters evaluated, mean values for platelet distribution width (PDW) and mean activities …

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Detection Of Caga And Vaca Genotypes Of Helicobacter Pylori Isolates From A University Hospital In Ankara Region, Turkey, Ceren Erdoğdu, Zeynep Saribaş, Yakut Akyön Yilmaz Jan 2014

Detection Of Caga And Vaca Genotypes Of Helicobacter Pylori Isolates From A University Hospital In Ankara Region, Turkey, Ceren Erdoğdu, Zeynep Saribaş, Yakut Akyön Yilmaz

Turkish Journal of Medical Sciences

The cagA and vacA profiles and their association with clinical findings show a distinct geographical distribution. In the present study, we aimed to determine the cagA status and vacA allelic subtypes in strains isolated from a university hospital in Ankara and to evaluate their associations with histopathological and endoscopic findings. Materials and methods: A total of 120 H. pylori strains from stock cultures positive for the ureA gene were randomly included in the present study. Of these strains, cagA and vacA allelic subtypes (s1a, s1b, s2, m1, m2) were examined by polymerase chain reaction. Results: Of the 120 strains, 64 …

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Evaluation Of Malaria Cases In Individuals After Traveling To Endemic Regions Of The World, Hülya Çaşkurlu, Emi̇ne Pakir, Aslihan Çolak Jan 2014

Evaluation Of Malaria Cases In Individuals After Traveling To Endemic Regions Of The World, Hülya Çaşkurlu, Emi̇ne Pakir, Aslihan Çolak

Turkish Journal of Medical Sciences

This study evaluates types of malaria and treatment success in a series of identified cases among individuals who were presumed to have travelled to regions where malaria is endemic. Materials and methods: In Sema Hospital, 25 cases of malaria (5 in women, 20 in men) were diagnosed during the 6-year period between 2006 and 2012. The mean age of the patients was 34.5 years. Diagnoses were established with thick and thin peripheral blood smears that were parasite-positive. These tests were then compared to the rapid diagnostic test based on Plasmodium falciparum histidine-rich protein 2. Results: All cases demonstrated fever beginning …

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Intrathoracic Castleman Disease, Pinar Biçakçioğlu, Seli̇m Şaki̇r Erkmen Gülhan, Leyla Nesri̇n Acar, Yetki̇n Ağaçkiran, Şeref Özkara, Sadi̇ Kaya, Nuretti̇n Karaoğlanoğlu Jan 2014

Intrathoracic Castleman Disease, Pinar Biçakçioğlu, Seli̇m Şaki̇r Erkmen Gülhan, Leyla Nesri̇n Acar, Yetki̇n Ağaçkiran, Şeref Özkara, Sadi̇ Kaya, Nuretti̇n Karaoğlanoğlu

Turkish Journal of Medical Sciences

To analyze patients with Castleman disease who were diagnosed by surgery. Materials and methods: We retrospectively investigated the postoperative pathological records of operations performed between January 1992 and December 2012 in our hospital. Files of 19 patients with the diagnosis of Castleman disease were analyzed. Results: There were 13 male and 6 female patients with a mean age of 40.1 ± 11.4 (range: 20-57) years. Fifteen thoracotomies and 3 video-assisted thoracoscopies, 12 on the right side and 6 on the left side, and 1 mediastinoscopy were performed. Biopsies and mass excisions were performed in 2 and 17 cases, respectively. Histopathological …

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Mefv Mutation Frequency And Effect On Disease Severity In Ankylosing Spondylitis, Yüksel Maraş, Ali̇ Akdoğan, Bünyami̇n Kisacik, Levent Kiliç, Engi̇n Yilmaz, Abdurrahman Tufan, Umut Kalyoncu, Şazi̇ye Şule Apraş Bi̇lgen, Sedat Ki̇raz, Ali̇ İhsan Ertenli̇, Meral Çalgüneri̇ Jan 2014

Mefv Mutation Frequency And Effect On Disease Severity In Ankylosing Spondylitis, Yüksel Maraş, Ali̇ Akdoğan, Bünyami̇n Kisacik, Levent Kiliç, Engi̇n Yilmaz, Abdurrahman Tufan, Umut Kalyoncu, Şazi̇ye Şule Apraş Bi̇lgen, Sedat Ki̇raz, Ali̇ İhsan Ertenli̇, Meral Çalgüneri̇

Turkish Journal of Medical Sciences

To define the frequency of familial Mediterranean fever gene (MEFV) mutations in ankylosing spondylitis (AS) and describe different clinical aspects of MEFV mutation carrier and noncarrier AS patients. Materials and methods: In 112 AS patients, Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) and Bath Ankylosing Spondylitis Functional Index (BASFI) scores were calculated. The frequencies of 12 different MEFV mutations were studied by multiplex polymerase chain reaction/reverse hybridization method and were compared to those of previously studied healthy controls for 5 common MEFV mutations. Results: MEFV mutations were identified in 46 of 224 (20%) alleles and in 39 (35%) of AS …

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Addition Of Epirubicin To Conventional Chemotherapy In Patients With Advanced Ovarian Cancer: Sequential Therapy - A Retrospective Evaluation, Nejat Özgül, Mehmet Faruk Köse, Hüseyi̇n Levent Keski̇n, Ahmet Taner Turan, Mustafa Alper Karalök, Işin Üreyen, Nuretti̇n Boran, Hakki Gökhan Tulunay Jan 2014

Addition Of Epirubicin To Conventional Chemotherapy In Patients With Advanced Ovarian Cancer: Sequential Therapy - A Retrospective Evaluation, Nejat Özgül, Mehmet Faruk Köse, Hüseyi̇n Levent Keski̇n, Ahmet Taner Turan, Mustafa Alper Karalök, Işin Üreyen, Nuretti̇n Boran, Hakki Gökhan Tulunay

Turkish Journal of Medical Sciences

To evaluate the effectiveness of the addition of epirubicin to conventional chemotherapy as a first-line therapy for stage III–IV epithelial ovarian cancer. Materials and methods: A total of 132 patients who had undergone primary cytoreductive surgery between January 1998 and March 2003 were enrolled in the study. Twenty-four cases were excluded. Out of the remaining 108 subjects, 35 received epirubicin/paclitaxel/carboplatin (Group EPC) and 73 were treated with paclitaxel/platinum (cisplatin or carboplatin) (Group PC). Results: The median follow-up period was 66.5 months. The clinical complete response was 94% in the EPC group and 97% in the PC group. The recurrence rate …

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Comparison Of Disc And Body Volumes In Degenerated And Nondegenerated Lumbar Discs: A Stereological Study, Tuncay Kaner, Ahmet Songur, Muhsi̇n Toktaş, Ozan Alper Alkoç, Olcay Eser, Mustafa Efendi̇oğlu Jan 2014

Comparison Of Disc And Body Volumes In Degenerated And Nondegenerated Lumbar Discs: A Stereological Study, Tuncay Kaner, Ahmet Songur, Muhsi̇n Toktaş, Ozan Alper Alkoç, Olcay Eser, Mustafa Efendi̇oğlu

Turkish Journal of Medical Sciences

To carry out comparison and correlation analyses of the intervertebral disc (IVD) and vertebral body (VB) volumes in magnetic resonance (MR) images of patients with degenerated and nondegenerated lumbar discs. Materials and methods: MR images were examined retrospectively in 93 patients. Lumbar VB and IVD volumes in T1-T2 weighted sagittal MR images were calculated via the Cavalieri method, a stereological method. Volumetric changes in degenerated and nondegenerated discs were compared. Results: The percentages of degenerated IVDs were 12.9%, 12.9%, 28%, 50.5%, and 52% in discs from levels L1 to L5, respectively. There were no differences in VB volumes between the …

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The Association Of Nocturia With Sleep Disorders And Metabolic And Chronic Pulmonary Conditions: Data Derived From The Polysomnographic Evaluations Of 730 Patients, Si̇bel Ayik, Kaan Bal, Gali̇p Akhan Jan 2014

The Association Of Nocturia With Sleep Disorders And Metabolic And Chronic Pulmonary Conditions: Data Derived From The Polysomnographic Evaluations Of 730 Patients, Si̇bel Ayik, Kaan Bal, Gali̇p Akhan

Turkish Journal of Medical Sciences

To evaluate the prevalence of nocturia among different degrees of obstructive sleep apnea (OSA) and its association with various clinical conditions. Materials and methods: In 730 OSA patients, the prevalence and frequency of nocturia was determined, and the association of nocturia with clinical and laboratory variables such as the apnea-hypopnea index (AHI), apnea duration, and minimum oxygen saturation and clinical conditions such as diabetes mellitus, coronary heart disease, and chronic obstructive pulmonary disease (COPD) was determined. Results: The overall prevalence of nocturia (>=2 wakes/night) was 50.9%. Prevalences of nocturia in simple snoring and mild, moderate, and severe OSA patients …

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New Hemostatic Agent: The Effect Of Ankaferd Blood Stopper On Healing Wounds In Experimental Skin Incision Model, Serdar Yüce, Celal Çandirli, Si̇bel Yeni̇dünya, Bünyami̇n Muslu Jan 2014

New Hemostatic Agent: The Effect Of Ankaferd Blood Stopper On Healing Wounds In Experimental Skin Incision Model, Serdar Yüce, Celal Çandirli, Si̇bel Yeni̇dünya, Bünyami̇n Muslu

Turkish Journal of Medical Sciences

To conduct a histopathological evaluation of the effects of Ankaferd Blood Stopper (ABS) on healing wounds in a rabbit skin incision model. Materials and methods: Incisions were performed on the backs of rabbits. The first incision was allowed to undergo normal secondary healing. ABS (1 mL) was applied to the second incision, which was subsequently allowed to undergo secondary healing. The third incision was sutured. ABS (1 mL) was applied to the fourth incision, which was subsequently sutured. During the wound healing period, the histopathologic signs of ulceration, inflammation, the proliferative phase, and the extent of early remodeling were comparatively …

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Epidemiology Of Uveitis In A Referral Hospital In Turkey, Müge Pinar Çakar Özdal, Alper Yazici, Melek Tüfek, Faruk Öztürk Jan 2014

Epidemiology Of Uveitis In A Referral Hospital In Turkey, Müge Pinar Çakar Özdal, Alper Yazici, Melek Tüfek, Faruk Öztürk

Turkish Journal of Medical Sciences

To investigate the causes and clinical characteristics of uveitis in patients presenting to a specialized eye hospital in Turkey. Materials and methods: The clinical records of 1028 uveitis patients admitted between 1990 and 2010 were retrospectively reviewed. Age at first presentation, sex, laterality, etiology, associated systemic disease, clinical presentation, and course of the disease were noted. Results: The mean age at presentation was 36.23 ± 14.9 years. Males constituted 58.2% of patients. Anatomically, anterior uveitis (42%) was most common, followed by posterior uveitis (24.9%), panuveitis (24.7%), and intermediate uveitis (8.4%). The course of the disease was mostly chronic (65.7%). The …

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The Role Of Ct And Mri In The Diagnosis Of Sigmoid Volvulus, Sabri̇ Selçuk Atamanalp, Abdulmeci̇t Kantarci, Bünyami̇ Özoğul, Abdullah Kisaoğlu, Refi̇k Seli̇m Atamanalp Jan 2014

The Role Of Ct And Mri In The Diagnosis Of Sigmoid Volvulus, Sabri̇ Selçuk Atamanalp, Abdulmeci̇t Kantarci, Bünyami̇ Özoğul, Abdullah Kisaoğlu, Refi̇k Seli̇m Atamanalp

Turkish Journal of Medical Sciences

Letter to the Editor

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Effects Of Intraabdominal Pressure On Mean Platelet Volume During Laparoscopic Cholecystectomy, Rüçhan Bahadir Celep, Şahi̇n Kahramanca, Mustafa Özsoy, Cem Azili, Süleyman Çeti̇nkünar, Ahmet Oğuz Hasdemi̇r, Hakan Güzel, Gülay Özgehan, İbrahi̇m Çolhan, Tevfi̇k Hadi̇ Küçükpinar Jan 2014

Effects Of Intraabdominal Pressure On Mean Platelet Volume During Laparoscopic Cholecystectomy, Rüçhan Bahadir Celep, Şahi̇n Kahramanca, Mustafa Özsoy, Cem Azili, Süleyman Çeti̇nkünar, Ahmet Oğuz Hasdemi̇r, Hakan Güzel, Gülay Özgehan, İbrahi̇m Çolhan, Tevfi̇k Hadi̇ Küçükpinar

Turkish Journal of Medical Sciences

Intraabdominal hypertension is a common occurrence, especially in intensive care unit patients, and it has high mortality and morbidity rates. The onset is commonly insidious and the poor prognosis is attributed to the long delay in diagnosis. Unfortunately, diagnosis is often delayed until loss of function in the affected tissues has already occurred. The aim of this study was to determine the predictive value of mean platelet volume (MPV) in assessing the risk of intraabdominal hypertension. Materials and methods: Pneumoperitoneum during elective laparoscopic cholecystectomy was used as a model for intraabdominal hypertension. The study included 103 patients who met the …

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Refeeding Hypophosphatemia: A Potentially Fatal Danger In The Intensive Care Unit, Ramazan Coşkun, Kürşat Gündoğan, Süleyman Baldane, Muhammet Güven, Murat Sungur Jan 2014

Refeeding Hypophosphatemia: A Potentially Fatal Danger In The Intensive Care Unit, Ramazan Coşkun, Kürşat Gündoğan, Süleyman Baldane, Muhammet Güven, Murat Sungur

Turkish Journal of Medical Sciences

To determine the overall and comparative incidence of refeeding hypophosphatemia (RH) between enteral and parenteral nutrition in general adult intensive care unit (ICU) patients. Materials and methods: This study was performed as a retrospective analysis. A total of 117 patients who received enteral and parenteral nutrition were included in the study. Demographic characteristics, type of nutrition, daily energy intake, and serum phosphorus levels before and after the initiation of the nutrition were recorded for 7 days. Results: The mean age of the patients was 65.8 ± 16.7 years. RH was found in 61 patients (52.14%). There was no significant difference …

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The Mcgrath Series 5 Video Laryngoscope Versus The Macintosh Laryngoscope: A Randomized Trial In Obstetric Patients, Semi̇h Arici, Serkan Karaman, Serkan Doğru, Tuğba Karaman, Hakan Tapar, Asker Zeki̇ Özsoy, Zi̇ya Kaya, Mustafa Süren Jan 2014

The Mcgrath Series 5 Video Laryngoscope Versus The Macintosh Laryngoscope: A Randomized Trial In Obstetric Patients, Semi̇h Arici, Serkan Karaman, Serkan Doğru, Tuğba Karaman, Hakan Tapar, Asker Zeki̇ Özsoy, Zi̇ya Kaya, Mustafa Süren

Turkish Journal of Medical Sciences

Anesthesiologists have encountered various difficulties in securing the airway. Therefore, we compare the intubation times and hemodynamic changes between the McGrath Series 5 video laryngoscope and the Macintosh laryngoscope. Materials and methods: A total of 80 obstetric patients were divided into 2 groups, orotracheally intubated with either the McGrath video laryngoscope or the Macintosh laryngoscope. The intubation times, Cormack-Lehane grade, percentage of glottic opening, mean arterial blood pressure, and heart rates were compared among the groups. Results: Intubation time in the McGrath video laryngoscope group was significantly longer than in the Macintosh laryngoscope group (P < 0.01). The percentage of glottic opening was found to be higher in the McGrath video laryngoscope group (P = 0.002). Conclusion: The McGrath Series 5 video laryngoscope provides excellent views during orotracheal intubation in obstetric anesthesia with normal airways.

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The Impact Of Antibiotic-Impregnated Catheters On Ventriculoperitoneal Shunt Infection, Mehmet Sorar, Uygur Er, Pinar Özişik, Ersi̇n Özeren, Serkan Şi̇mşek Jan 2014

The Impact Of Antibiotic-Impregnated Catheters On Ventriculoperitoneal Shunt Infection, Mehmet Sorar, Uygur Er, Pinar Özişik, Ersi̇n Özeren, Serkan Şi̇mşek

Turkish Journal of Medical Sciences

Ventriculoperitoneal shunt infections remain an important problem and result mainly from perioperative colonization of shunt components by skin flora. Antibiotic-impregnated shunts have been designed to prevent such colonization. This study evaluates the incidence of shunt infection after the insertion of antibiotic-impregnated shunts in a population of children with hydrocephalus. Materials and methods: All pediatric patients who had undergone cerebrospinal fluid shunt insertion retrospectively were reviewed over a 6-year period between May 2004 and December 2010. The primary outcome measure was the rate of shunt infections. Patients were followed up with for an average of 26.2 months after shunt surgery, and …

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Distribution Of The Hypoglossal Nerve At The Base Of The Tongue And Its Clinical Importance In Radiofrequency Ablation Therapy, Nesri̇n Çandir, Sedat Develi̇, Cenk Kiliç, Bülent Satar, Fati̇h Yazar Jan 2014

Distribution Of The Hypoglossal Nerve At The Base Of The Tongue And Its Clinical Importance In Radiofrequency Ablation Therapy, Nesri̇n Çandir, Sedat Develi̇, Cenk Kiliç, Bülent Satar, Fati̇h Yazar

Turkish Journal of Medical Sciences

To identify the course of the hypoglossal nerve at the base of tongue and to determine a safe area for the placement of radiofrequency ablation therapy (RAT) probes to protect the nerve trunk from any damage. Materials and methods: Anatomical structures located at the base of the tongue were investigated in 10 cadaveric human half-heads. On the base of our landmarks, which are clinically important sign points, measurements were made. Results: The safe area was found to be: in the transverse plane, the 1/2 medial part of the half-tongue between the lateral edge and the foramen caecum of the tongue, …

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Comparison Of The Efficacy Of Prednisolone, Montelukast, And Omalizumab In An Experimental Allergic Rhinitis Model, Mete Kaan Bozkurt, Baykal Tülek, Banu Bozkurt, Nalan Akyürek, Mehmet Öz, Aysel Kiyici Jan 2014

Comparison Of The Efficacy Of Prednisolone, Montelukast, And Omalizumab In An Experimental Allergic Rhinitis Model, Mete Kaan Bozkurt, Baykal Tülek, Banu Bozkurt, Nalan Akyürek, Mehmet Öz, Aysel Kiyici

Turkish Journal of Medical Sciences

To compare the efficacy of prednisolone, montelukast, and omalizumab in reducing allergic symptoms and inflammation at tissue level in an experimental allergic rhinitis model. Materials and methods: Forty Sprague Dawley rats were randomized into 5 groups as naive (NS/NC), sensitized/challenged (S/C) by subcutaneous ovalbumin antigen injection, and montelukast-, prednisolone-, and omalizumab-treated groups. A nasal allergen challenge was performed every day from day 20 to day 26. The number of sneezes and nasal/eye rubbing movements, IL-4 and CysLT levels in serum, nasal and bronchoalveolar lavage fluids determined by ELISA, and histopathological findings of nasal mucosa, sinus, and lung tissues were compared. …

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Diastolic Function Of The Right Ventricle Is Impaired In Experimental Type 2 Diabetic Rat Models, Ya Miao, Wei Zhang, Yuan Zhong, Ming Zhong, Xiao Ma Jan 2014

Diastolic Function Of The Right Ventricle Is Impaired In Experimental Type 2 Diabetic Rat Models, Ya Miao, Wei Zhang, Yuan Zhong, Ming Zhong, Xiao Ma

Turkish Journal of Medical Sciences

To evaluate diastolic function alterations of the right ventricle (RV) by echocardiography in type 2 diabetic rat models. Materials and methods: Male Wistar rats were divided into 2 groups: a control group (n = 8) and a diabetic group (n = 16, with 11 remaining at the end of the experiment), which was fed a high-fat and high-calorie diet and injected with streptozotocin (STZ). RV diastolic functional alteration of rat models was studied by the tricuspid flow Doppler (Ep, Ap, and Ep/Ap) and tissue Doppler imaging (TDI) (Em, Am, and Em/Am) of the lateral tricuspid annulus. RV structural alteration of …

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Protective Effect Of L-Carnitine In A Rat Model Of Retinopathy Of Prematurity, Sadullah Keleş, İbrahi̇m Caner, Orhan Ateş, Özgür Çakici, Fati̇h Saruhan, Uğur Yilmaz Mumcu, Deni̇z Ünal, Kadi̇r Şerafetti̇n Tekgündüz, Ayhan Taşteki̇n, Ahmet Hacimüftüoğlu, Nesri̇n Gürsan, Hami̇t Hakan Alp Jan 2014

Protective Effect Of L-Carnitine In A Rat Model Of Retinopathy Of Prematurity, Sadullah Keleş, İbrahi̇m Caner, Orhan Ateş, Özgür Çakici, Fati̇h Saruhan, Uğur Yilmaz Mumcu, Deni̇z Ünal, Kadi̇r Şerafetti̇n Tekgündüz, Ayhan Taşteki̇n, Ahmet Hacimüftüoğlu, Nesri̇n Gürsan, Hami̇t Hakan Alp

Turkish Journal of Medical Sciences

To investigate the effects of L-carnitine (LC) on rats with oxygen-induced retinopathy. Materials and methods: The study was conducted on 40 Sprague Dawley rat pups. The rat pups were randomly divided into 4 groups: group 1 (n = 10), the healthy control group with intraperitoneal 0.1 mL/day physiological saline injection; group 2 (n = 10), exposed to hyperoxygen, did not receive LC but received 0.1 mL/day physiological saline intraperitoneally; group 3 (n = 10), exposed to hyperoxygen and received 100 mg/kg/day LC intraperitoneally; group 4 (n = 10), exposed to hyperoxygen and received 200 mg/kg/day LC intraperitoneally. After postnatal day …

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The Effect Of Manipulatives On Students' Understanding Of Chemistry Concepts, Jasmine W. Banks Jan 2014

The Effect Of Manipulatives On Students' Understanding Of Chemistry Concepts, Jasmine W. Banks

LSU Master's Theses

The purpose of this study was to assess the effectiveness of manipulatives on chemistry concepts. Manipulative activities were designed for four chemistry topics: Dimensional Analysis, Ionic Formulas, Molecular Shapes, and Stoichiometry. Seventy-five high school students were divided into a control or experimental group. The control group solved problems in small groups, while the experimental group used manipulatives to complete a guided activity. Students in the control group scored significantly higher on the posttest for the Dimensional Analysis and Ionic Formulas activities. There was no significant difference in the posttest scores for the Molecular Shapes and Stoichiometry posttest. While manipulatives can …

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Regulation Of Oocyte Meiotic Resumption Using Camp Modulators In Bovine In Vitro Maturation, Sarah Farmer Jan 2014

Regulation Of Oocyte Meiotic Resumption Using Camp Modulators In Bovine In Vitro Maturation, Sarah Farmer

LSU Master's Theses

In vitro maturation (IVM) is a reproductive technique critical to in vitro embryo production (IVP) in commercial livestock industries, research, and human infertility treatment. Currently, IVP has low efficiency due to an inadequate IVM system in which premature meiotic resumption results in low oocyte viability. Meiotic arrest is regulated primarily by 3’,5’-cyclic adenosine monophosphate (cAMP), and the most successful methods of improving IVM utilize cAMP modulators to maintain high intra-oocyte cAMP, delaying the onset of maturation. This thesis includes experiments comparing standard bovine IVM to a novel extended IVM method similar to the procedure described by Albuz and colleagues (Albuz …

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Disparities In Accessibility To Pharmacies: A Case Study In East Baton Rouge Parish, Louisiana, Samina Zahid Ikram Jan 2014

Disparities In Accessibility To Pharmacies: A Case Study In East Baton Rouge Parish, Louisiana, Samina Zahid Ikram

LSU Master's Theses

Accessibility is a term used to define the relative ease by which activities or services, such as work, recreation, shopping, education or healthcare, can be accessed from a given location. It is an important locational amenity for residents. This study examines accessibility to over 100 pharmacies in Baton Rouge, Louisiana, in 2010. Accessibility to a pharmacy is critical for a community as it is the prime source to get medication and other health services. First, two Geographic Information Systems (GIS) based methods, namely the proximal area method and the two-step floating catchment area (2SFCA) method, are used to measure the …

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The Feasibility Of Creating A 3d Digital Skeletal Collection For Research Purposes And Museum Use, Karen Leigh Beebe Jan 2014

The Feasibility Of Creating A 3d Digital Skeletal Collection For Research Purposes And Museum Use, Karen Leigh Beebe

LSU Master's Theses

3D scanners offer many advantages to scientists and museum curators, such as a permanent digital archival record of the scanned object, the non-intrusive nature of 3D laser surface scanning, the ability to create and share a digital collection with other researchers, and the portability of recent scanners. With the purpose of determining the feasibility of creating a 3D research collection in mind, I have scanned and studied skeletal material from Wild Cane Cay and Moho Cay, Belize. I explore how the 3D model compares to the physical bone and the significance of 3D imaging to the anthropological community.

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Effect Of Process Mixing On The Size Distribution And Mean Diameter Of The Thiol-Triacrylate Microcapsules, Rubaiyet Abedin Jan 2014

Effect Of Process Mixing On The Size Distribution And Mean Diameter Of The Thiol-Triacrylate Microcapsules, Rubaiyet Abedin

LSU Master's Theses

An important limitation in the development of the microparticles is the difficulty to develop a precise size distribution. Microparticles have a wide spread applicability in different fields including medical, pharmaceutical, textile, cosmetics, pesticide, printing industry, etc. The large and growing impact of microencapsulation in different fields of technology has made this process important. Microparticle size is a primary determinant of control release mechanism and the reaction kinetics and also impacts the allowable routes of administration, The main objective of this research work is to evaluate the effect of the process mixing on the size and size distribution of the trithiol-triacrylate …

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An Experimental Investigation Of The Effects Of N-Decane On The Supercritical Pyrolysis Of Toluene, Catherine A. Grubb Jan 2014

An Experimental Investigation Of The Effects Of N-Decane On The Supercritical Pyrolysis Of Toluene, Catherine A. Grubb

LSU Master's Theses

Future and current high-speed jet aircraft will require their fuels to act as the primary coolants as well as propellants. Fuels will be exposed to severe temperatures and pressures in hypersonic aircraft, up to 700°C and 130 atm, respectively, conditions that are supercritical for most pure hydrocarbons. Under supercritical conditions, hydrocarbon fuels undergo pyrolytic reactions, which may lead to the formation of polycyclic aromatic hydrocarbons (PAH), known precursors to carbonaceous solid deposits. Such deposits may clog fuel lines and injection nozzles, hindering safe engine performance. Hence, it is important to understand the reactions that lead to the formation of PAH. …

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Assimilation, A Biological Nitrogen Removal Strategy For Freshwater Ornamental Fish Hatcheries, Fatemehsadat Fahandezhsadi Jan 2014

Assimilation, A Biological Nitrogen Removal Strategy For Freshwater Ornamental Fish Hatcheries, Fatemehsadat Fahandezhsadi

LSU Master's Theses

Freshwater ornamental fish production is a major component of aquaculture in the southeastern United States. Closed recirculating aquaculture systems (RASs) allow freshwater ornamental fish hatcheries to mimic native water quality conditions for sensitive species. Total ammonia-N (TAN) removal is the major concern for closed RASs. Biological nitrification is the common method to control TAN. However, the nitrification process might be impaired in acidic water condition with pH<7. Another issue of using the nitrification process for TAN removal is that the nitrification is not sufficient to compensate for the amount of ammonia released in larval production systems because of slow growth rate of nitrifying bacteria. To address these issues, this study suggests an aerobic assimilation strategy in which fast growing heterotrophic bacteria directly convert TAN into microbial biomass. The heterotrophic bacteria needs an external carbon source. This study employed polyhydroxybutyrate (PHB) that is a solid insoluble bioplastic, as a carbon source in the aerobic assimilation process to avoid releasing carbon into the system. In order to understand the applicability of an assimilation process instead of nitrification, this study compared the ammonia-N removal rate by aerobic assimilation biofilters operating @ pH 8 and 6.5 in a batch system. The study also quantified the performance of an aerobic assimilation strategy under different continuous nitrogen loading regimes. This investigation can be used to establish the biofilter air pulsing frequency, which is the optimized air pulsing frequency that avoids clogging in the system. The results showed that there was no apparent release of carbon in the water tank. Unlike nitrification, assimilation strategy for TAN removal was not significantly different in two pH of 8 and 6.5 @ 28 ° C. The average consumption rate of the PHB was found as 21.93± 0.43 grams of PHB consumed per gram of TAN. The results from the continuous system, at a continuous feeding rate of 350 mg-N/d, suggested that the optimum air pulsing frequency through the PHB bed for releasing the excess biosolids was about 6-hour. In general, the study found that the aerobic assimilation using polyhydroxybutyrate (PHB) as a carbon source is an applicable method for ammonia-N removal particularly for freshwater ornamental fish production systems. The drawback against this approach is that the PHB beads are expensive. However, our investigations show that the average cost of the PHB beads have been decreased dramatically during the last few years. This might indicate that the assimilation using PHB beads can be a reasonable choice for ammonia-N removal particularly for freshwater ornamental fish production systems.

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Habitat Associations Of Lower Mississippi River Floodplain Fishes On St. Catherine Creek National Wildlife Refuge, Alonda Mccarty Jan 2014

Habitat Associations Of Lower Mississippi River Floodplain Fishes On St. Catherine Creek National Wildlife Refuge, Alonda Mccarty

LSU Master's Theses

Each year, floodplain habitats are inundated and dewatered throughout the lower Mississippi River during the flood pulse. Many organisms, particularly fishes, are facultative or obligate users of inundated floodplain habitats for foraging and reproduction. The abundance and distribution of these fishes are influenced by annual floods, ranging from weeks to months depending on intensity and duration of the pulse. One major consequence of anthropogenic alterations to the river has been the sequential loss of connectivity of floodplain habitats. In light of these changes, a concentrated effort has been made to restore the integrity of the LMR floodplain. An integral part …

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The Development Of A Novel Silicon On Insulator Microdosimeter With Sensitive Volumes Modeled After Living Cells, Anthony P. Mazza Jan 2014

The Development Of A Novel Silicon On Insulator Microdosimeter With Sensitive Volumes Modeled After Living Cells, Anthony P. Mazza

LSU Master's Theses

Purpose: The purpose of this work was to test the feasibility of using a silicon on insulator microdosimeter, which mimics the size and shape of particular cells within the human body, to determine dose equivalent from a 239PuBe neutron source with uncertainty less than 10%. Methods: A batch of microdosimeters were analyzed in terms of their physical surface conditions and basic diode characteristics such as leakage current as a function of bias voltage, to select those with the best performance. A calibration protocol was developed utilizing an 241Am alpha particle source and a reference tail pulse generator. Neutron spectra were …

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Change In Developmental Quotient In Toddlers Assessed For Autism Spectrum Disorder, Lindsey Willis Williams Jan 2014

Change In Developmental Quotient In Toddlers Assessed For Autism Spectrum Disorder, Lindsey Willis Williams

LSU Master's Theses

ASD is marked by significant delays in social and language development, while development in other areas, such as cognitive functioning, can be highly variable from person to person. Though preschool-aged children with ASD often exhibit a profile of developmental delays similar to children with other developmental disorders at a discrete moment in time, few studies have investigated possible differences in rate of skill acquisition in developmental domains in children with different disorders. Sensitive periods of development are marked by less stability in performance of developmental skills. Results of prior studies suggest that if appropriate early interventions are applied during sensitive …

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