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Traumatic Brain Injury And The Americans With Disabilities Act: Implications For The Social Work Profession, Dale Margolin Cecka Jan 2014

Traumatic Brain Injury And The Americans With Disabilities Act: Implications For The Social Work Profession, Dale Margolin Cecka

Law Faculty Publications

The practice of social work has been greatly affected by the Americans with Disabilities Act of 1990 (ADA). Title I of the statute prohibits discrimination against people with disabilities, including the increasing number of workers who are returning to work after a traumatic brain injury (TBI). This article examines the extent to which the ADA protects those with TBI from being harassed, being denied reasonable workplace accommodations, or suffering other adverse actions related to perceived discrimination. To do so, it relies on judicial decisions from U.S. federal courts involving alleged workplace discrimination of this population. Implications for social work practice …


Climate Change Triage, Noah M. Sachs Jan 2014

Climate Change Triage, Noah M. Sachs

Law Faculty Publications

Climate change is the first global triage crisis. It is caused by the overuse of a severely limited natural resource—the atmosphere’s capacity to absorb greenhouse gases—and millions of lives depend on how international law allocates this resource among nations.

This Article is the first to explore solutions for climate change mitigation through the lens of triage ethics, drawing on law, philosophy, moral theory, and economics. The literature on triage ethics—developed in contexts such as battlefield trauma, organ donation, emergency medicine, and distribution of food and shelter—has direct implications for climate change policy and law, yet it has been overlooked by …


Administrative Law, John Paul Jones Jan 2014

Administrative Law, John Paul Jones

Law Faculty Publications

This article is a report of certain developments during the last two years relating to the Virginia Administrative Process Act ("the VAPA"), which governs rulemaking and adjudication of cases by state agencies as well as judicial review of both.


Public Policy Research & Drafting: A Pro Bono And Law Library Collaboration, Tara L. Casey, Suzanne B. Corriell Jan 2014

Public Policy Research & Drafting: A Pro Bono And Law Library Collaboration, Tara L. Casey, Suzanne B. Corriell

Law Faculty Publications

As the Carrico Center for Pro Bono Service at the University of Richmond School of Law continued to grow its programs, forays into the areas of public policy and advanced legal research grew as well. for a number of years, our law students volunteered with nonprofit organizations during the General Assembly session, learning firsthand how issues develop into policy, which sometimes then develops into Jaw. This experience required our students to expand their legal research and writing skills beyond the traditional case law and brief writing methods. Furthermore, a growing number of students were interested in pursuing legislative or public …


Lack Of Sexual Size Dimorphism In Sceloporus Poinsettii From Durango, Mexico, J. A. Lemos-Espinal, Geoffrey R. Smith, John B. Iverson, Juan Manuel Morales Sandoval Jan 2014

Lack Of Sexual Size Dimorphism In Sceloporus Poinsettii From Durango, Mexico, J. A. Lemos-Espinal, Geoffrey R. Smith, John B. Iverson, Juan Manuel Morales Sandoval

Faculty Publications

No abstract provided.


Justice And Immigrant Latino Recreation Geography In Cache Valley, Utah, Jodie Madsen, Claudia Radel, Joanna Endter-Wada Jan 2014

Justice And Immigrant Latino Recreation Geography In Cache Valley, Utah, Jodie Madsen, Claudia Radel, Joanna Endter-Wada

Environment and Society Faculty Publications

Latinos are the largest U.S. non-mainstreamed ethnic group, and social and environmental justice considerations dictate recreation professionals and researchers meet their recreation needs. This study reconceptualizes this diverse group’s recreation patterns, looking at where immigrant Latino individuals in Cache Valley, Utah do recreate rather than where they do not. Through qualitative interviews and interactive mapping, thirty participants discussed what recreation means to them and explained their recreation site choices. Findings suggest that recreation as an activity done outside the home, for fun with others, leads participants to seek spaces with certain characteristics. Reconceiving recreation more broadly and framing it from …


Sign Up Or Sign Off: Asia’S Reluctant Engagement With The International Criminal Court, Mark Findlay Jan 2014

Sign Up Or Sign Off: Asia’S Reluctant Engagement With The International Criminal Court, Mark Findlay

Research Collection Yong Pung How School Of Law

The International Criminal Court argues that there is a need to achieve universal ratification so that the majority of mankind will no longer remain outside the protection of the ICC. In the Asia/Pacific region there is a relatively low accession rate of nation states to the Rome Statute. This paper proposes a taxonomy of resistance to ratification in the region, recognising that in speculating on the reasons for resistance to the ratification of international criminal justice, local to the global across Asia and the Pacific, there is a risk in both over emphasising cultural and political difference while at the …


Ratings Lead You To The Product, Reviews Help You Clinch It? The Dynamics And Impact Of Online Review Sentiments On Products Sales, Nan Hu, Noi Sian Koh, Srinivas K. Reddy Jan 2014

Ratings Lead You To The Product, Reviews Help You Clinch It? The Dynamics And Impact Of Online Review Sentiments On Products Sales, Nan Hu, Noi Sian Koh, Srinivas K. Reddy

Research Collection Lee Kong Chian School Of Business

It is generally assumed that ratings are a numeric representation of text sentiments and their valences are consistent. This however may not always be true. Using a panel of data on over 4000 books from Amazon.com, we develop a multiple equation model to examine the inter-relationships between ratings, sentiments, and sales. We find that ratings do not have a significant direct impact on sales but have an indirect impact through sentiments. Sentiments, however, have a direct significant impact on sales. Our findings also indicate that the two most accessible types of reviews - most helpful and most recent - play …


Anticipated Regret In Time-Based Work-Family Conflict, Jessica Bagger, Jochen Reb, Andrew Li Jan 2014

Anticipated Regret In Time-Based Work-Family Conflict, Jessica Bagger, Jochen Reb, Andrew Li

Research Collection Lee Kong Chian School Of Business

The primary purpose of this research was to investigate the role of anticipated regret in time-based work-family conflict decisions.

A total of 90 working parents responded to a decision making problem describing a time-based conflict between a work event and a family event. Participants' preference for which event to attend constituted the dependent variable. Independent variables were participants' work and family centralities. Anticipated regret for choosing the work option and anticipated regret for choosing the family option were measured as hypothesized mediators.

Structural equation modeling revealed that anticipated regret for choosing the family option mediated the relationship between work centrality …


Refocusing The Lens: Singapore's Private Enterprises In China, Caroline Yeoh, Wilfred Pow Ngee How, Ye Zhang Jan 2014

Refocusing The Lens: Singapore's Private Enterprises In China, Caroline Yeoh, Wilfred Pow Ngee How, Ye Zhang

Research Collection Lee Kong Chian School Of Business

In recent years, financial and political instabilities have cooled economic growth in many regions. Even in this context, however, areas of strong growth remain; none, arguably, more prominent than ever-developing and increasingly affluent China, which is today a vastly different environment than even several years ago. More than ever, a wealth of opportunity subsists in this ancient land – and businesses must be able to adapt and seize these opportunities. Thus we turn towards Singapore private enterprise in China, to study once more the efficacy of the city-state's internationalization strategies in the context of the private enterprises which must eventually …


Sox, Corporate Transparency, And The Cost Of Debt, Sandro Andrade, Gennaro Bernile, Frederick Hood Jan 2014

Sox, Corporate Transparency, And The Cost Of Debt, Sandro Andrade, Gennaro Bernile, Frederick Hood

Research Collection Lee Kong Chian School Of Business

We investigate the impact of the Sarbanes–Oxley (SOX) Act on the cost of debt through its effect on the reliability of financial reporting. Using Credit Default Swap (CDS) spreads and a structural CDS pricing model, we calibrate a firm-level corporate opacity parameter in the pre- and post-SOX periods. Our analysis shows that corporate opacity and the cost of debt decrease significantly after SOX. The median firm in our sample experiences an 18 bp reduction on its five-year CDS spread as a result of lower opacity following SOX, amounting to total annual savings of $ 844 million for the 252 firms …


Tracking-Error Models For Multiple Benchmarks: Theory And Empirical Performance, Yunchao Xu, Zhichao Zheng, Karthik Natarajan, Chung-Piaw Teo Jan 2014

Tracking-Error Models For Multiple Benchmarks: Theory And Empirical Performance, Yunchao Xu, Zhichao Zheng, Karthik Natarajan, Chung-Piaw Teo

Research Collection Lee Kong Chian School Of Business

We propose a new multiple-benchmark tracking-error model for portfolio selection problem. The tracking error of a portfolio from a set of benchmark portfolios is defined as the difference between its return and the highest return from the set of benchmarks. We derive closedform solution of our portfolio strategy, whose main component is the sum of the benchmark portfolios weighted by their respective probabilities of attaining the highest return among the portfolios in the benchmark. These probabilities, also known as the persistency values, are less sensitive to estimation errors in the means and covariances. These features help to stabilize the computational …


Transforming Business School Futures: Business Model Innovation And The Continued Search For Academic Legitimacy, Howard Thomas, Eric Cornuel Jan 2014

Transforming Business School Futures: Business Model Innovation And The Continued Search For Academic Legitimacy, Howard Thomas, Eric Cornuel

Research Collection Lee Kong Chian School Of Business

The business school is certainly one of the major success stories in higher education over the last 40 years. Despite this success there have been many more recent comments and criticisms and about the purpose, role and academic stature of business schools. Thomas et al. (2013, pp. 8-9) outline thoroughly the nature of these criticisms in the following manner: “Critics accuse business schools of doing arcane, irrelevant and impractical academic research; doing a poor job of preparing students for management careers; pandering to the market and the media rankings; failing to ask important questions; and in the process of responding …


Early Discontinuation Of Endocrine Therapy For Breast Cancer: Who Is At Risk In Clinical Practice?, Anna Kemp, David Preen, Christobel Saunders, Francis Boyle, Max Bulsara, Eva Malacova, Elizabeth E. Roughead Jan 2014

Early Discontinuation Of Endocrine Therapy For Breast Cancer: Who Is At Risk In Clinical Practice?, Anna Kemp, David Preen, Christobel Saunders, Francis Boyle, Max Bulsara, Eva Malacova, Elizabeth E. Roughead

Medical Papers and Journal Articles

Purpose: Despite evidence supporting at least five years of endocrine therapy for early breast cancer, many women discontinue therapy early. We investigated the impact of initial therapy type and specific comorbidities on discontinuation of endocrine therapy in clinical practice.

Methods

We identified women in a population-based cohort with a diagnosis of early breast cancer and an incident dispensing of anastrozole, letrozole or tamoxifen from 2003-2008 (N = 1531). Pharmacy and health service data were used to determine therapy duration, treatment for pre-existing and post-initiation comorbidities (anxiety, depression, hot flashes, musculoskeletal pain, osteoporosis, vaginal atrophy), demographic and other clinical characteristics. Time …


Multimorbidity In A Marginalised, Street-Health Australian Population: A Retrospective Cohort Study, Tom Brett, Diane Arnold-Reed, Lakkina Troeung, Max Bulsara, Annalise Williams, Robert G. Moorhead Jan 2014

Multimorbidity In A Marginalised, Street-Health Australian Population: A Retrospective Cohort Study, Tom Brett, Diane Arnold-Reed, Lakkina Troeung, Max Bulsara, Annalise Williams, Robert G. Moorhead

Medical Papers and Journal Articles

OBJECTIVES:

Demographic and presentation profile of patients using an innovative mobile outreach clinic compared with mainstream practice.

DESIGN:

Retrospective cohort study.

SETTING:

Primary care mobile street health clinic and mainstream practice in Western Australia.

PARTICIPANTS:

2587 street health and 4583 mainstream patients.

MAIN OUTCOME MEASURES:

Prevalence and patterns of chronic diseases in anatomical domains across the entire age spectrum of patients and disease severity burden using Cumulative Illness Rating Scale (CIRS).

RESULTS:

Multimorbidity (2+ CIRS domains) prevalence was significantly higher in the street health cohort (46.3%, 1199/2587) than age-sex-adjusted mainstream estimate (43.1%, 2000/4583), p=0.011. Multimorbidity prevalence was significantly higher in …


External Validation Of The Garvan Nomograms For Predicting Absolute Fracture Risk: The Tromso Study, Luai A. Ahmed, Nguyen D. Nguyen, Ashild Bjornerem, Ragnar M. Joakimsen, Lone Jorgensen, Jan Stormer, Dana Bliuc, Jacqueline R. Center, John A. Eisman, Tuan V. Nguyen, Nina Emaus Jan 2014

External Validation Of The Garvan Nomograms For Predicting Absolute Fracture Risk: The Tromso Study, Luai A. Ahmed, Nguyen D. Nguyen, Ashild Bjornerem, Ragnar M. Joakimsen, Lone Jorgensen, Jan Stormer, Dana Bliuc, Jacqueline R. Center, John A. Eisman, Tuan V. Nguyen, Nina Emaus

Medical Papers and Journal Articles

Background: Absolute risk estimation is a preferred approach for assessing fracture risk and treatment decision making. This study aimed to evaluate and validate the predictive performance of the Garvan Fracture Risk Calculator in a Norwegian cohort.

Methods: The analysis included 1637 women and 1355 aged 60+ years from the Tromsø study. All incident fragility fractures between 2001 and 2009 were registered. The predicted probabilities of non-vertebral osteoporotic and hip fractures were determined using models with and without BMD. The discrimination and calibration of the models were assessed.Reclassification analysis was used to compare the models performance.

Results: The incidence of osteoporotic …


High Expression Of Cathepsin E In Tissues But Not Blood Of Patients With Barrett’S Esophagus And Adenocarcinoma, Oliver M. Fisher, Angelique J. Levert-Mignon, Sarah J. Lord, Natalie K. Botelho, Araluen K. Freeman, Melissa L. Thomas, Dan Falkenback, Antony Wettstein, David C. Whiteman, Yuri V. Bobryshev, Reginald V. Lord Jan 2014

High Expression Of Cathepsin E In Tissues But Not Blood Of Patients With Barrett’S Esophagus And Adenocarcinoma, Oliver M. Fisher, Angelique J. Levert-Mignon, Sarah J. Lord, Natalie K. Botelho, Araluen K. Freeman, Melissa L. Thomas, Dan Falkenback, Antony Wettstein, David C. Whiteman, Yuri V. Bobryshev, Reginald V. Lord

Medical Papers and Journal Articles

Background Cathepsin E (CTSE), an aspartic proteinase, is differentially expressed in the metaplasia–dysplasia–neoplasia sequence of gastric and colon cancer. We evaluated CTSE in Barrett’s esophagus (BE) and cancer because increased CTSE levels are linked to improved survival in several cancers, and other cathepsins are up-regulated in BE and esophageal adenocarcinoma (EAC). Methods A total of 273 pretreatment tissues from 199 patients were analyzed [31 normal squamous esophagus (NE), 29 BE intestinal metaplasia, 31 BE with dysplasia (BE/D), 108 EAC]. CTSE relative mRNA expression was measured by real-time polymerase chain reaction, and protein expression was measured by immunohistochemistry. CTSE serum levels …


Eye Trauma Epidemiology In Regional Australia, Luke C. Northey, Gaurav Bhardwaj, Shane Curran, Joseph Mcgirr Jan 2014

Eye Trauma Epidemiology In Regional Australia, Luke C. Northey, Gaurav Bhardwaj, Shane Curran, Joseph Mcgirr

Medical Papers and Journal Articles

Purpose: To describe the epidemiology of eye trauma presenting to a regional referral health service in New South Wales, Australia.

Methods: A two-stage retrospective and prospective case series study was conducted. Patients who presented with eye trauma to Wagga Wagga Base Hospital (WWBH) emergency department (ED) during a one year review period formed the retrospective case series (RCS). Patient inclusion was determined using SNOMED CT and ICD-10 codes applied to medical records. Patients presenting with eye trauma to the WWBH ED or its ophthalmology service over a prospective 80 day study period formed the prospective case series (PCS). The …


Case Series Of Elective Instrumented Posterior Lumbar Spinal Fusions Demonstrating A Low Incidence Of Venous Thromboembolism, Benjamin Weber, Alexa Seal, Joseph Mcgirr, Kerin Fielding Jan 2014

Case Series Of Elective Instrumented Posterior Lumbar Spinal Fusions Demonstrating A Low Incidence Of Venous Thromboembolism, Benjamin Weber, Alexa Seal, Joseph Mcgirr, Kerin Fielding

Medical Papers and Journal Articles

Introduction: Venous thromboembolism (VTE) is a significant cause of morbidity and mortality in orthopaedic surgery. While specific guidelines exist for hip and knee arthroplasty, there is wide variation in VTE prophylaxis in complex spinal surgery. This study sought to determine the incidence of VTE, and risk factors associated with VTE, in patients undergoing elective instrumented posterior lumbar spinal fusion.

Methods: In a single-centre case series study, 107 consecutive patients undergoing elective lumbar spinal fusion were evaluated for VTE by lower limb duplex ultrasonography and/or clinical observation, and where indicated, computed tomography pulmonary angiogram (CTPA). The Caprini model for thrombosis risk …


Domestic Violence Is A Leading Risk Factor In Default From Colposcopy Services, Rachael R. Collier, Julie Quinlivan Jan 2014

Domestic Violence Is A Leading Risk Factor In Default From Colposcopy Services, Rachael R. Collier, Julie Quinlivan

Medical Papers and Journal Articles

Aim: Domestic violence is common in women and is associated with poorer healthcare outcomes. However, no causal pathway has been identified to explain this observation. We have followed a cohort of women to determine whether poorer outcomes can be explained by high rates of default and lost to follow up.

Methods: A prospective cohort study was performed. Institutional ethics approval was obtained. Participants were consecutive patients attending colposcopy clinics at a major metropolitan hospital in Australia. Following ascertainment of domestic violence status, appointment outcomes for colposcopy services were tracked for a three-year period. Multivariate analysis was undertaken to determine demographic …


Evaluating The Guideline Enhancement Tool (Get): An Innovative Clinical Training Tool To Enhance The Use Of Hypertension Guidelines In General Practice, Chinthaka Balasooriya, Joel Rhee, Boaz Shulruf, Rosa Canalese, Nicholas Zwar Jan 2014

Evaluating The Guideline Enhancement Tool (Get): An Innovative Clinical Training Tool To Enhance The Use Of Hypertension Guidelines In General Practice, Chinthaka Balasooriya, Joel Rhee, Boaz Shulruf, Rosa Canalese, Nicholas Zwar

Medical Papers and Journal Articles

Background: This project aims to evaluate the effectiveness of an innovative educational intervention in enhancing clinical decision making related to the management of hypertension in general practice. The relatively low level of uptake of clinical practice guidelines by clinicians is widely recognised as a problem that impacts on clinical outcomes. This project addresses this problem with a focus on hypertension guidelines. Hypertension is the most frequently managed problem in general practice but evidence suggests that management of Hypertension in general practice is sub-optimal.

Methods/design: This study will explore the effectiveness of an educational intervention named the ‘Guideline Enhancement Tool (GET)’. …


Unmet Needs Of Patients With Chronic Obstructive Pulmonary Disease (Copd): A Qualitative Study On Patients And Doctors, S Wong, N Abdullah, A Abdullah, S Liew, S Ching, E Khoo, M Jiwa, Y Chia Jan 2014

Unmet Needs Of Patients With Chronic Obstructive Pulmonary Disease (Copd): A Qualitative Study On Patients And Doctors, S Wong, N Abdullah, A Abdullah, S Liew, S Ching, E Khoo, M Jiwa, Y Chia

Medical Papers and Journal Articles

Background: Chronic Obstructive Pulmonary Disease (COPD) is a chronic disease with repeated exacerbations resulting in gradual debilitation. The quality of life has been shown to be poor in patients with COPD despite efforts to improve self-management. However, the evidence on the benefit of self-management in COPD is conflicting. Whether this could be due to other unmet needs of patients have not been investigated. Therefore, we aimed to explore unmet needs of patients from both patients and doctors managing COPD.

Methods: We conducted a qualitative study with doctors and patients in Malaysia. We used convenience sampling to recruit patients until data …


Management Of Behavioural Change In Patients Presenting With A Diagnosis Of Dementia: A Video Vignette Study With Australian General Practitioners, M Jiwa, P Nichols, P Magin, G Pagey, X Meng, R Parsons, V Pillai Jan 2014

Management Of Behavioural Change In Patients Presenting With A Diagnosis Of Dementia: A Video Vignette Study With Australian General Practitioners, M Jiwa, P Nichols, P Magin, G Pagey, X Meng, R Parsons, V Pillai

Medical Papers and Journal Articles

Objective: To test the impact of feedback on the proposed management of standardised patients presenting with behavioural change with a diagnosis of dementia in Australian primary care.

Materials and methods: A video vignette study was performed with Australian general practitioners (GPs) in 2013. Participants viewed six pairs of matched videos depicting people presenting changed behavior in the context of a dementia diagnosis in two phases. In both phases GPs indicated their diagnosis and management. After phase 1, GPs were offered feedback on management strategies for the patients depicted. Analyses focused on identification of change in management between the two phases …


Rating General Practitioner Consultation Performance In Cancer Care: Does The Specialty Of Assessors Matter? A Simulated Patient Study, M Jiwa, G Halkett, X Meng, M Berg Jan 2014

Rating General Practitioner Consultation Performance In Cancer Care: Does The Specialty Of Assessors Matter? A Simulated Patient Study, M Jiwa, G Halkett, X Meng, M Berg

Medical Papers and Journal Articles

Background: Patients treated for prostate cancer may present to general practitioners (GPs) for treatment follow up, but may be reticent to have their consultations recorded. Therefore the use of simulated patients allows practitioner consultations to be rated. The aim of this study was to determine whether the speciality of the assessor has an impact on how GP consultation performance is rated.

Methods: Six pairs of scenarios were developed for professional actors in two series of consultations by GPs. The scenarios included: chronic radiation proctitis, Prostate Specific Antigen (PSA) ‘bounce’, recurrence of cancer, urethral stricture, erectile dysfunction and depression or anxiety. …


A Randomised Trial Deploying A Simulation To Investigate The Impact Of Hospital Discharge Letters On Patient Care In General Practice, M Jiwa, X Meng, C O'Shea, P Magin, A Dadich, V Pillai Jan 2014

A Randomised Trial Deploying A Simulation To Investigate The Impact Of Hospital Discharge Letters On Patient Care In General Practice, M Jiwa, X Meng, C O'Shea, P Magin, A Dadich, V Pillai

Medical Papers and Journal Articles

Objective: To determine how the timing and length of hospital discharge letters impact on the number of ongoing patient problems identified by general practitioners (GPs).

Trial design: GPs were randomised into four groups. Each viewed a video monologue of an actor-patient as he might present to his GP following a hospital admission with 10 problems. GPs were provided with a medical record as well as a long or short discharge letter, which was available when the video was viewed or 1 week later. GPs indicated if they would prescribe, refer or order tests for the patient’s problems.

Methods: Setting Primary …


Genomic Catastrophes Frequently Arise In Esophageal Adenocarcinoma And Drive Tumorigenesis, K Nones, N Waddell, N Wayte, A Patch, P Bailey, F Newell, O Holmes, J Fink, M Quinn, Y Tang, G Lampe, K Quek, K Loffler, S Manning, S Idrisoglu, D Miller, Q Xu, N Waddell, P Wilson, T Bruxner, A Christ, I Harliwong, C Nourse, E Nourbakhsh, M Anderson, S Kazakoff, C Leonard, S Wood, P Simpson, L Reid, L Krause, D Hussey, D Watson, R Lord, D Nancarrow, W Phillips, D Gotley, B Smithers, D Whiteman, N Hayward, P Campbell, J Pearson, S Grimmond, A Barbour Jan 2014

Genomic Catastrophes Frequently Arise In Esophageal Adenocarcinoma And Drive Tumorigenesis, K Nones, N Waddell, N Wayte, A Patch, P Bailey, F Newell, O Holmes, J Fink, M Quinn, Y Tang, G Lampe, K Quek, K Loffler, S Manning, S Idrisoglu, D Miller, Q Xu, N Waddell, P Wilson, T Bruxner, A Christ, I Harliwong, C Nourse, E Nourbakhsh, M Anderson, S Kazakoff, C Leonard, S Wood, P Simpson, L Reid, L Krause, D Hussey, D Watson, R Lord, D Nancarrow, W Phillips, D Gotley, B Smithers, D Whiteman, N Hayward, P Campbell, J Pearson, S Grimmond, A Barbour

Medical Papers and Journal Articles

Oesophageal adenocarcinoma (EAC) incidence is rapidly increasing in Western countries. A better understanding of EAC underpins efforts to improve early detection and treatment outcomes. While large EAC exome sequencing efforts to date have found recurrent loss-offunction mutations, oncogenic driving events have been underrepresented. Here we use a combination of whole-genome sequencing (WGS) and single-nucleotide polymorphism-array profiling to show that genomic catastrophes are frequent in EAC, with almost a third (32%, n¼40/123) undergoing chromothriptic events. WGS of 22 EAC cases show that catastrophes may lead to oncogene amplification through chromothripsis-derived double-minute chromosome formation (MYC and MDM2) or breakage-fusion-bridge (KRAS, MDM2 and …


Health Inequalities And Development Plans In Iran: An Analysis Of The Past Three Decades (1984–2010), H Zare, A Trujillo, J Driessen, M Ghasemi, G Gallego Jan 2014

Health Inequalities And Development Plans In Iran: An Analysis Of The Past Three Decades (1984–2010), H Zare, A Trujillo, J Driessen, M Ghasemi, G Gallego

Medical Papers and Journal Articles

Introduction: Reducing inequalities in health care is one of the main challenges in all countries. In Iran as in other oil-exporting upper middle income countries, we expected to witness fewer inequalities especially in the health sector with the increase in governmental revenues.

Methods: This study presents an inequalities assessment of health care expenditures in Iran. We used data from the Household Income and Expenditure Survey (HIES) in Iran from 1984–2010. The analysis included 308,735 urban and 342,532 rural households.

Results: The results suggest heightened inequality in health care expenditures in Iran over the past three decades, including an increase in …


Robot-Assisted Gastrectomy And Oesophagectomy For Cancer, Dan Falkenback, Christopher W. Lehane, Reginald V.N Lord Jan 2014

Robot-Assisted Gastrectomy And Oesophagectomy For Cancer, Dan Falkenback, Christopher W. Lehane, Reginald V.N Lord

Medical Papers and Journal Articles

Background: Robot-assisted surgery is a technically feasible alternative to open and laparoscopic surgery, which is being more frequently used in general surgery. We undertook this review to investigate whether robotic assistance provides a significant benefit for oesophagogastric cancer surgery.

Methods: Electronic databases were searched for original English-language publications for robotic-assisted gastrectomy and oesophagectomy between January 1990 and October 2013.

Results: Sixty-one publications were included. Thirty-five included gastrectomy, 31 included oesophagectomy and five included both operations. Several publications suggest that robot-assisted subtotal gastrectomy can be as safe and effective as an open or laparoscopic procedure, with equal outcomes with regard to …


Financial Reporting Opacity And Expected Crash Risk: Evidence From Implied Volatility Smirks, Jeong-Bon Kim, Liandong Zhang Jan 2014

Financial Reporting Opacity And Expected Crash Risk: Evidence From Implied Volatility Smirks, Jeong-Bon Kim, Liandong Zhang

Research Collection School Of Accountancy

The recent financial crisis has stimulated a renewed interest in understanding the determinants of stock price crash risk (i.e., left tail risk). Recent research shows that opaque financial reports enable managers to hide and accumulate bad news for extended periods. When the accumulated bad news reaches certain tipping point, it will be suddenly released to the market at once, resulting in an abrupt decline in stock price (i.e., a crash). This study extends this line of research by examining the impact of financial reporting opacity on perceived or expected crash risk. Prominent economists, such as Olivier Blanchard, argue that removing …


Beauty And Academic Career, Hai Lu, Yanju Liu, Kevin Veenstra Jan 2014

Beauty And Academic Career, Hai Lu, Yanju Liu, Kevin Veenstra

Research Collection School Of Accountancy

We examine the impact of beauty on the academic career success of tenure-track accounting professors at top business schools in America, and show that beauty plays a significant role. Specifically, after controlling for gender, ethnicity, publication history, work experience, and quality of alma mater, more attractive professors obtain better first school placements post-PhD and are granted tenure in a shorter period of time. Interestingly, there is no incremental benefit of attractiveness for the career progression from associate to full professor. These findings are consistent with our conjecture that when the signal of an individual’s potential is noisy, beauty becomes a …