Digital Commons Network^™

A Systems Biology Approach To Detect Eqtls Associated With Mirna And Mrna Co-Expression Networks In The Nucleus Accumbens Of Chronic Alcoholic Patients, Mohammed Mamdani

Theses and Dissertations

Alcohol Dependence (AD) is a chronic substance use disorder with moderate heritability (60%). Linkage and genome-wide association studies (GWAS) have implicated a number of loci; however, the molecular mechanisms underlying AD are unclear. Advances in systems biology allow genome-wide expression data to be integrated with genetic data to detect expression quantitative trait loci (eQTL), polymorphisms that regulate gene expression levels, influence phenotypes and are significantly enriched among validated genetic signals for many commonly studied traits including AD.

We integrated genome-wide mRNA and miRNA expression data with genotypic data from the nucleus accumbens (NAc), a major addiction-related brain region, of 36 …

Dr. Who?: The Science And Culture Of Medical Wear Design, Patricia Duignan

Theses and Dissertations

The multi-million-dollar medical uniform industry has not utilized advancements in garment and textile technology that could positively impact the protection of healthcare professionals and patients. In most cases the uniforms meet basic requirements – they clothe the professional in a recognizable way. Little innovation in design, function and performance, has been applied to these garments. This is particularly evident in the case of the stereotypical white lab coat worn by many physicians, despite evidence indicating that these lab coats may carry contamination and play a role in the spread of deadly bacteria. Healthcare Associated Infections (HAIs) are among the most …

Pursuing The Roles Of Non-Invasive Biomarkers In Chronic Renal Allograft Dysfunction, Mba Uzoma U. Mba

Theses and Dissertations

Kidney failure affects over 600,000 people in the United States with over 100,000 new cases of kidney failure diagnosed every year. Chronic allograft dysfunction (CAD), a disease state highlighted by a decreased eGFR and a histo-pathological diagnosis interstitial fibrosis and renal tubular atrophy, has emerged as one of the leading causes of kidney transplantation. Gene expression analysis can identify reproducible patterns of disease in ribonucleic acid (RNA) expression and may provide insights into the quality of kidney donations heretofore overlooked by current clinical analytical methods. Additionally, genetic expression profiles can be obtained from patient blood or urine samples, diminishing the …

Theorizing When User Reaction To It Implementation Is Neither Resistance Nor Acceptance, But Constructive Behavior: A Case Study Of Healthcare It Implementation, Kaveh Mohajeri

Theses and Dissertations

The prevailing discourse of “resistance vs. acceptance” in IT implementation research mostly personalizes the issue as “users” versus IT implementers (e.g., managers, CIOs, CMIOs, etc.). This kind of discourse has created an IT-implementer-centric attitude among IS scholars and practitioners. The IT-implementer-centric attitude, while embraces “acceptance” as a desirable reaction almost unconditionally, frequently holds for minimizing or more conservatively suppressing “resistance” to IT implementation. In other words, the mainstream IT implementation research, almost completely, treats “users” as passive recipients whose choices, as they face pre-developed/pre-designed/pre-rolled-out technology being implemented, can only be defined on a spectrum from “acceptance” to “resistance.” The current …

Longitudinal Relations Between Peer Victimization And Delinquency: The Mediating Roles Of Sadness, Fear, And Anger, Lisa J. Ulmer

Theses and Dissertations

Peer victimization is a common occurrence among youth, and it has been linked to a number of negative outcomes, including delinquent behaviors (e.g., physical aggression, theft/property damage, and substance use). Several studies examined relations between peer victimization and delinquency, though few have done so longitudinally or examined whether negative emotions are underlying processes that explain associations between these constructs. The current study’s purpose is to examine whether several negative emotions (i.e., anger, fear, and sadness) mediate relations between several types of peer victimization and delinquency among middle and high school youths. The study’s sample of 318 youths was predominately African …

Water Is A Girl’S Best Friend: Examining The Water Valuation Dilemma, Amy Hardberger

Faculty Articles

Water allocation is currently controlled by policy that assigns a property right and hopes to protect the resource and its users. Markets can help fill this void and increase efficiency by assigning an accurate value to the good and dictating how the water is transferred and used.

Unfortunately, current markets lack the ability to send an accurate price signal that reflects the true value of water, leading to unintended consequences that could rapidly deplete resources rather than protect them. For the market to be accurate in pricing water, all costs must be included, allowing consumers to make an informed decision. …

Scientific, Legal, And Ethical Foundations For Texas Water Law., Gabriel Eckstein, Amy Hardberger

Faculty Articles

Water law is the field of law concerned with the ownership, control, and use of water resources, both surface and subsurface. Although most closely related to property law, recent developments in other legal fields, especially in environmental law, have heavily influenced the interpretation, application, and development of water law. As a result, water law today encompasses a broad perspective and often takes into account individual and community rights, environmental issues, commerce and economics, and other societal and legal concerns. Significantly, modern water law is also an interdisciplinary practice. In light of the continuously expanding body of knowledge of the hydrologic …

Lost And Found: David Hoffman And The History Of American Legal Ethics, Michael S. Ariens

Faculty Articles

David Hoffman was a successful Baltimore lawyer who wrote the first study of American

law in 1817 and authored the first maxims of American legal ethics. Yet for more than a century after his death, Hoffman was a forgotten figure to American lawyers. Beginning in the late 1970s, Hoffman was re-discovered, and his writings on legal ethics have been favorably cited.

How and why was Hoffman “lost” to American law for over a century, and why he was “found”? Hoffman was lost to history because his view of ethics was premised on republican virtue, specifically the concept of honor. A …

The Texas Supreme Court: A Narrative History, 1836–1986 (Book Review), Michael S. Ariens

Faculty Articles

The historical material and resources available for American legal historians is both too much and too little. Hundreds of published case opinions became thousands of opinions by the end of the 1820s, leading lawyers to conclude that no one could know the entirety of the law. Yet this cascade of information is also too little, because the work of treatise writers and magazine editors of the time was ruthlessly focused on then-existing legal concerns.

For these reasons, James L. Haley works within difficult strictures in his book, The Texas Supreme Court: A Narrative History, 1836–1986. Because his story is about …

The Agony Of Modern Legal Ethics, 1970–1985, Michael S. Ariens

Faculty Articles

When the American Bar Association (ABA) adopted its Code of Professional Responsibility at its annual meeting in August 1969, the American legal profession was a publicly respected and economically vibrant body. Lawyers, though always more feared than loved, became increasingly important in post-World War II America. The demand for their services exploded for a quarter-century, and lawyers assumed an increased role in the economic and political life of the United States. During the 1950s and early 1960s, the Cold War led American lawyers and other public figures to re-emphasize the rule of law as defining the difference between the United …

Punitive Damages, Chinese Tort Law, And The American Experience, Vincent R. Johnson

Faculty Articles

In a country such as China, with abundant consumer products and the inevitability of product defects, claims for punitive damages are sure to arise under Article 47 of the new Chinese Tort Law. Article 47 provides that “(w)hereany producer or seller knowingly produces or sells defective products, causing death or serious damage to the health of others, the injured party may request appropriate punitive damages.” As Chinese jurists and scholars interpret Article 47, they may wish to consider whether lessons can be drawn from the American experience. During the past two decades, few areas of American law have changed more …

Minimizing The Costs Of Patent Trolling, Vincent R. Johnson

Faculty Articles

Patent trolling is a serious legal problem. In addressing patent trolling, disclosure requirements and periodic reporting standards will be critical to minimizing the costs of this controversial practice.

Patent trolling, at its most problematic, generally refers to patent infringement allegations made by non-practicing entities (NPEs) which produce essentially no products or services except in connection with the buying and selling of patent rights. The targets of these patent “trolls” often lack basic information that is relevant to their evaluation of the claims against them, and policymakers know too little about specialized patent assertion entities and their impact on innovation and …

Using A Civil Suit To Punish/Deter Sponsors Of Terrorism: Connecting Arafat & The Plo To The Terror Attacks In The Second Intifada, Jeffrey F. Addicott

Faculty Articles

Civil litigation has fantastic potential to punish acts of terror and to deter future acts. However, there exists a conundrum regarding the establishment of the factual connection between the regime that secretly sponsors or supports terror and the actual acts of terror. To hold a regime responsible for terrorism, accountability must be established.

The ongoing civil action of Sokolow v. The Palestine Liberation Organization (PLO) perfectly illustrates this dilemma—on the one hand the offending regime disavows acts of terror while on the other hand it secretly supports and orchestrates terror. However, Yasser Arafat, President of the Palestinian National Assembly (PNA), …

Tocqueville's Nightmare: The Administrative State Emerges In America, 1900-1940 (Book Review), Michael Ariens

Faculty Articles

No abstract provided.

Increasing Military Social Work Knowledge: An Evaluation Of Learning Outcomes., Mary Ann Forgey, Sharon L Young

Social Service Faculty Publications

Service members and veterans face a myriad of health mental health and social challenges stemming from the combat and operational stressors experienced during deployment and the challenges of reintegration to civilian life. To intervene effectively with this population social workers must be knowledgeable about these issues and the cultural context within which they occur. While schools of social work across the country are developing course work in military social work, little is known about the learning outcomes of these courses. This paper describes a military social work course that was developed to increase student preparedness to work with a military …

Protective Webs: Exploring A Role For School Social Workers On Behalf Of Delinquent Youths, Lauri Goldkind

Social Service Faculty Publications

Annually, 100,000 delinquent youths return to their communities from a detention facility and are required to attend a community school. School social workers may be best positioned to provide assistance with this transition; however, little is understood about how they are presently servicing this population. This study explores the interactions of school social workers and the advocacy and assistance they provide on behalf of juvenile justice youths. The author surveyed a national sample of current school social workers (n D 4,279) and reports on their involvement with juvenile justice, their work on behalf of the youths’ families as well as …

E-Advocacy In Human Services: The Impact Of Organizational Conditions And Characteristics On Electronic Advocacy Activities Among Nonprofits, Lauri Goldkind

Social Service Faculty Publications

E-advocacy, or the constellation of electronic tools used for policy advocacy, offer cost-effective approaches for engaging constituents to create social change. Providers of human services may face challenges when trying to implement these tools. While many electronic tools have low barriers for entry, other factors may inhibit their use in agencies. This article explores the organizational characteristics related to the use of electronic advocacy strategies. Based on a survey of nonprofit executives, the study uses path modeling to describe the connections between organizational characteristics and the use of electronic advocacy tools. Implications of these findings are discussed.

Developing The Law Of The River: The Integration Of Law And Policy Into Hydrologic And Socio-Economic Modeling Efforts In The Willamette River Basin, Adell Louise Amos

Publications

A legal and policy infrastructure -- referred to as a "law of the river" -- exists for every river basin in the U.S. an can be as important as natural processes in terms of managing the future of the resource. Because of the way that water law and policy have evolved in the U.S., this infrastructure involves a matrix of state and federal law that governs the choices that policymakers, end users, and agencies make. This "law of the river" provides the context in which decisions are made and not made. It also draws the boundaries within which decision makers …

Inspiration By Nature: Biomimetic Research Informs Adaptable Building Skin System For Natural Ventilation And Daylight In Hot Dry Climate (Yazd, Iran), Parisa Navidi

Master's Theses

Many plant species, including Barrel Cacti, have developed long-term evolutionary adaptable traits to survive in extreme climates. The most important trait of cacti in extreme hot dry climates is to reduce water evaporation and increase water storage. The exterior skin of a cactus plays an important role in preventing water evaporation through heat transmission.

On the other hand, there have been many passive design strategies applied to the space planning and building design of architecture in hot dry climates. The goal of these passive design strategies is to regulate the penetration of heat into building spaces while creating a strong …

The Disconnect Between College And Reality, Janice Bell Underwood, Elizabeth Burns

STEMPS Faculty Publications

With formative assessments, teachers can more accurately determine student interests and aptitudes and drive achievement.

Cover Letter, Allison F. Rienecker

Richmond Journal of Law & Technology

The Richmond Journal of Law and Technology is proud to present its Annual Survey issue of the 2013-2014 academic year. This issue is published in conjunction with JOLT’s Symposium entitled “Information Governance: A Comprehensive Approach to e-Discovery.” Since its founding in 1995, JOLT has strived to publish relevant legal articles at the forefront of the technological field. With this goal in mind, we are excited to expand JOLT’s respected discussion of e-Discovery to the emerging field of Information Governance.

Getting Serious: Why Companies Must Adopt Information Governance Measures To Prepare For The Upcoming Changes To The Federal Rules Of Civil Procedure, Philip J. Favro

Richmond Journal of Law & Technology

[W]ithout a corresponding change in discovery culture by courts, counsel and clients alike, the proposed rules modifications will likely have little to no effect on the manner in which discovery is conducted today.

Defensible Data Deletion: A Practical Approach To Reducing Cost And Managing Risk Associated With Expanding Enterprise Data, Dennis R. Kiker

Richmond Journal of Law & Technology

Modern businesses are hosts to steadily increasing volumes of data, creating significant cost and risk while potentially compromising the current and future performance and stability of the information systems in which the data reside. To mitigate these costs and risks, many companies are considering initiatives to identify and eliminate information that is not needed for any business or legal purpose (a process referred to herein as “data remediation”). There are several challenges for any such initiative, the most significant of which may be the fear that information subject to a legal preservation obligation might be destroyed.

Understanding And Contextualizing Precedents In E-Discovery: The Illusion Of Stare Decisis And Best Practices To Avoid Reliance On Outdated Guidance, Jonathan M. Redgrave, Keltie Hays Peay, Mathea K.E. Bulander

Richmond Journal of Law & Technology

But as precedents survive like the clavicle in the cat, long after the use they once served is at an end, and the reason for them has been forgotten, the result of following them must often be failure and confusion from the merely logical point of view.

Cover Letter, Benjamin R. Fox

Richmond Journal of Law & Technology

The Richmond Journal of Law and Technology is proud to present its third issue of the 2013-2014 academic year. First published in 1995, JOLT is the world’s first exclusively online law review. JOLT strives to discuss new and emerging issues that fall squarely at the intersection of technology and the law. With this goal in mind, we are proud to announce the publication of the following articles.

The Tangled Web: A Case Against New Generic Top-Level Domains, Joseph P. Smith Iii

Richmond Journal of Law & Technology

If we had a reliable way to label our toys good and bad, it would be easy to regulate technology wisely. But we can rarely see far enough ahead to know which road leads to damnation.

Cyborgs In The Courtroom: The Use Of Google Glass Recordings In Litigation, Kristin Bergman

Richmond Journal of Law & Technology

The future is now. Wearable computers such as Google Glass (Glass) have begun entering society—we see people wearing these devices on the streets, in classrooms, at parties, and elsewhere. Though most of these devices are not yet available to the public at large, there has been much hype over the impact Glass will have on our interactions, privacy, safety, and more. Although this Article will briefly address such controversial aspects, it will focus more narrowly on the potential utility of Glass in litigation.

Cover Letter, Benjamin R. Fox

Richmond Journal of Law & Technology

The Richmond Journal of Law and Technology is proud to present the final issue of the Twentieth Volume. First published in 1995, JOLT isthe world’s first exclusively online law review. JOLT strives to discuss new and emerging issues that fall squarely at the intersection oftechnology and the law. With this goal in mind, we are proud to announce the publication of the following articles.

Cyber Security Active Defense: Playing With Fire Or Sound Risk Management, Sean L. Harrington

Richmond Journal of Law & Technology

“Banks Remain the Top Target for Hackers, Report Says,” is the title of an April 2013 American Banker article. Yet, no new comprehensive U.S. cyber legislation has been enacted since 2002, and neither legislative history nor the statutory language of the Computer Fraud and Abuse Act (CFAA) or Electronic Communications Privacy Act (ECPA) make reference to the Internet. Courts have nevertheless filled in the gaps—sometimes with surprising results.

It’S Time For Revenge Porn To Get A Taste Of Its Own Medicine: An Argument For The Federal Criminalization Of Revenge Porn, Taylor Linkous

Richmond Journal of Law & Technology

Throughout history, pornography and technology have enjoyed a symbiotic relationship, each playing a significant role in the growth and widespread success of the other. From the VCR and camcorders to the Polaroid camera and the Internet, the pornography industry has always accelerated the growth of new technologies, paving the way for these new services to be introduced into mainstream society. Most of these new technologies were appealing to creators and consumers of pornography because the new technologies brought an increased sense of privacy. For example, much of the success of the Polaroid camera is said to come from the fact …