Digital Commons Network^™

How Much Dna Is Lost? Measuring Dna Loss Of Str Length Fragments Targeted By The Powerplex 16® System Using The Qiagen Minelute Purification Kit, Brian M. Kemp, Misa Winters, Cara Monroe, Jodi Lynn Barta

Human Biology Open Access Pre-Prints

The success in recovering genetic profiles from aged and degraded biological samples is diminished by fundamental aspects of DNA extraction, as well as its long-term preservation that are not well understood. While numerous studies have been conducted to determine whether one extraction method performed superior to others, nearly all of them were initiated with no knowledge of the actual starting DNA quantity in the samples prior to extraction, so they ultimately compared the outcome of all methods relative to the best. Using quantitative PCR (qPCR) to estimate the copy count of synthetic standards before (i.e., “copies in”) and after (i.e., …

A Conversation With D. Nurkse, Josh Brewer

Booth

Comfortably ensconced in a breakfast nook, poet D. Nurkse discussed the architecture of Butler’s Efromyson Center for Creative Writing (one way of talking about the relationship between labor and form), literary tradition, falling snow (visible through the window), and his parents leaving Europe as it disintegrated into World War II. We also discussed his use of baseball in poetry. Wizened and soft-spoken, he sipped coffee and reflected upon several decades of work. Nurkse’s career could have been different.

A Harvard graduate and son of an esteemed economist, he turned down an opportunity to pursue an international academic career. Instead, he …

Ua12/2/1 Stressbusters, Wku Student Affairs

WKU Administration Documents

Special finals week edition of the College Heights Herald.

• Horoscopes
• Color Me Gary Ransdell

The Bison, December 5, 2014

The Bison Newspapers

No abstract provided.

Design, Assessment, And In Vivo Evaluation Of A Computational Model Illustrating The Role Of Cav1 In Cd4+ T-Lymphocytes, Brittany D. Conroy, Tyler A. Herek, Timonthy D. Shew, Matthew Latner, Joshua J. Larson, Laura Allen, Paul H. Davis, Tomáš Helikar, Christine E. Cutucache

Department of Biochemistry: Faculty Publications

Caveolin-1 (CAV1) is a vital scaffold protein heterogeneously expressed in both healthy and malignant tissue. We focus on the role of CAV1 when overexpressed in T-cell leukemia. Previously, we have shown that CAV1 is involved in cell-to-cell communication, cellular proliferation, and immune synapse formation; however, the molecular mechanisms have not been elucidated.We hypothesize that the role of CAV1 in immune synapse formation contributes to immune regulation during leukemic progression, thereby warranting studies of the role of CAV1 in CD4⁺ T-cells in relation to antigen-presenting cells. To address this need, we developed a computational model of a CD4⁺ immune …

Deember 5, 2014- Board Of Trustees Meeting Minutes, Regular And Special Meetings, Central Washington University Central Washington University

Board of Trustees Meeting Minutes

Meeting minutes for the Regular Meeting of the Board of Trustees at Central Washington University, December 5, 2014.

Sensory Abnormalities In Focal Hand Dystonia And Non-Invasive Brain Stimulation, Angelo Quartarone, Vincenzo Rizzo, Carmen Terranova, Demetrio Milardi, Daniele Bruschetta, Maria Felice Ghilardi, Paolo Girlanda

Publications and Research

It has been proposed that synchronous and convergent afferent input arising from repetitive motor tasks may play an important role in driving the maladaptive cortical plasticity seen in focal hand dystonia (FHD).This hypothesis receives support from several sources. First, it has been reported that in subjects with FHD, paired associative stimulation produces an abnormal increase in corticospinal excitability, which was not confined to stimulated muscles. These findings provide support for the role of excessive plasticity in FHD. Second, the genetic contribution to the dystonias is increasingly recognized indicating that repetitive, stereotyped afferent inputs may lead to late-onset dystonia, such as …

Senior Recital: Haley Myers, Piano, Haley Myers

Bailey School of Music Concert Programs

This recital is presented in partial fulfillment of requirements for the degree Bachelor of Music in Performance. Ms. Myers studies piano with Soohyun Yun.

Avian Diversity Across Three Distinct Agricultural Landscapes In Guadalupe, Chiriquí Highlands, Panama, Jarred Jones

Independent Study Project (ISP) Collection

Deforestation of tropical forest for agricultural purposes threatens habitat loss of native species. The value of various agricultural landscapes in conserving avian populations is useful in determining diversity-conscious development plans. However, generalized results from regionalscale studies cannot be implemented to insular avian habitats. This study serves as the only current avian diversity study of the Chiriquí Highlands. To determine the effect of agricultural land use within an insular avian habitat, I compared avian diversity and site population similarity in Guadalupe, Chiriquí Highlands of the Talamanca Range, Panama. I hypothesized that avian diversity is greatest at forest edge followed by forest …

Improved Upper Limits On The Stochastic Gravitational-Wave Background From 2009-2010 Ligo And Virgo Data, Tiffany Summerscales, Ligo And Virgo Collaboration

Faculty Publications

Gravitational waves from a variety of sources are predicted to superpose to create a stochastic background. This background is expected to contain unique information from throughout the history of the Universe that is unavailable through standard electromagnetic observations, making its study of fundamental importance to understanding the evolution of the Universe. We carry out a search for the stochastic background with the latest data from the LIGO and Virgo detectors. Consistent with predictions from most stochastic gravitational-wave background models, the data display no evidence of a stochastic gravitational-wave signal. Assuming a gravitational-wave spectrum of ΩGW(f)=Ωα(f/fref)α, we place 95% confidence level …

Tuberculosis Interferon-Gamma Responses In The Breast Milk Of Human Immunodeficiency Virus Infected Mothers, Lisa Cranmer, Mercy Kanyugo, Barbara Lohman-Payne, Ken Tapia, Grace John-Stewart

Institute for Immunology and Informatics Faculty Publications

Tuberculosis (TB) cellular immune responses were examined in breastmilk of HIV-infected mothers using the T-SPOT.TB interferon gamma release assay (IGRA). Positive TB IFN-γ responses were detected in 6 of 8 (75%) valid breast milk assays. Among 7 mothers with paired breastmilk and blood assays, TB IFN- γ responses were higher in breastmilk compared to blood (p=.02). The magnitude of TB IFN-γ responses in maternal breastmilk and blood were correlated. Elucidating the influence of breastmilk TB immune responses on infant TB susceptibility and immunity may inform future maternal TB vaccine strategies.

Evaluating Management Strategies For Urban Stormwater Runoff, Corrina M. Fleischmann

Doctoral Dissertations

Urban stormwater runoff, a leading cause of waterway impairment, has become a focal point of urban stormwater management strategies. As urbanization increases, regulations demanding preservation of pre-development peak flow rates or runoff volumes have been implemented and low impact development (LID) is encouraged as a strategy to achieve this stormwater runoff reduction requirement. While the success of LID has been proven at the site-scale, limited watershed-scale assessment of LID has been conducted. This research explores the potential benefit of watershed-scale LID implementation on two common urban stormwater issues: degraded stream health and combined sewer overflows (CSOs). Assessment results indicate that …

Project Technologia: A Game-Based Approach To Understanding Situated Intentionality, Stephen Thomas Slota

Doctoral Dissertations

Since the early 2000s, educators, administrators, politicians, and researchers have given increased attention to the potential affordances of video games for educating K-12 and university learners. This has led to the instantiation of numerous game-based learning (GBL) journals, investigations of efficacy, achievement, and motivation using multimillion dollar tools, and a federally-funded competition for science, technology, engineering, and mathematics game development. Yet, little is known about the way particular game mechanics, narrative structures, and community-driven tools (e.g., forums, cheat guides, mods) influence the skills needed to be a successful 21^st century learner. Few studies have catalogued the particular actions and …

Small School, Big Reach: Open Access Outreach On A Liberal Arts College Campus, Janelle L. Wertzberger

All Musselman Library Staff Works

The liberal arts college environment provides opportunities for campus-wide engagement of open access issues that may differ from those at larger institutions. Because we support fewer campus authors, we are able to provide a high level of service. Librarians’ close connections with faculty and students allow us to move beyond articles and theses and solicit a wide range of scholarly and creative works to share in our repository. In addition, we’ve fostered conversations about open access, open textbooks, altmetrics, and copyright among faculty, staff, and students. This poster will present a snapshot of a variety of outreach and education strategies …

The New York Times Features Opinion Piece Written By Gardner-Webb Professor, Office Of University Communications

Gardner-Webb NewsCenter Archive

The world-renowned newspaper publication The New York Times has selected the work of a Gardner-Webb University history professor to appear in its online opinion/editorial section, which features commentary from a variety of authors on the 150th anniversary of the Civil War. GWU Assistant Professor of History Dr. Joseph Moore says recent research he completed relating to the history of Scottish Covenanters, Christianity, and early-American politics led him to pitch an idea to editors at The New York Times. The thought became reality on Thursday, Dec. 4 when his article, “Lincoln, God and the Constitution,” was published online at NYTimes.com.

Design, Assessment, And In Vivo Evaluation Of A Computational Model Illustrating The Role Of Cav1 In Cd4+ T-Lymphocytes, Brittany D. Conroy, Tyler A. Herek, Timothy D. Shew, Matthew Latner, Joshua J. Larson, Laura Allen, Paul H. Davis, Tomáš Helikar, Christine E. Cutucache

Biology Faculty Publications

Caveolin-1 (CAV1) is a vital scaffold protein heterogeneously expressed in both healthy and malignant tissue. We focus on the role of CAV1 when overexpressed in T-cell leukemia. Previously, we have shown that CAV1 is involved in cell-to-cell communication, cellular proliferation, and immune synapse formation; however, the molecular mechanisms have not been elucidated. We hypothesize that the role of CAV1 in immune synapse formation contributes to immune regulation during leukemic progression, thereby warranting studies of the role of CAV1 in CD4⁺ T-cells in relation to antigen-presenting cells. To address this need, we developed a computational model of a CD4^{+ …}

New Directions For Pilt, University Of Dayton

News Releases

University of Dayton School of Law Dean Paul McGreal announced Friday, Dec. 5, the appointment of law professor Tracy Reilly as director of the school's Program in Law and Technology (PILT).

Daily Eastern News: December 05, 2014, Eastern Illinois University

December

No abstract provided.

Famine In Context: Possible Long-Term Effects Of Exposure To Starvation And Malnutrition In Early Life And Subsequent Implications For The Current Crisis In South Sudan, Jenna Mae Stoken

Honors Projects

Central focus

The central focus of this thesis is to examine the historical and sociopolitical roots of famine. In examining the root causes of famine, we can more carefully analyze its effects on the human condition. More specifically, in analyzing the pathologies associated with food deprivation and malnutrition at an early age, we can examine the possible long-term consequences of malnutrition on human health. In doing so, we can apply this understanding to the current crisis in South Sudan, to consider the implications that the current political situation presents for future generations of South Sudanese people.

Thesis rationale

This thesis …

Combating Eutrophication: An Ecosystem Scale Analysis Of Aluminum Sulfate (Alum) Effectiveness Among Lakes, With Comparison To Alum And Biomanipulation Dual Treatment, Christa M. Webber

School of Natural Resources: Dissertations, Theses, and Student Research

Eutrophic conditions in lakes and reservoirs in agricultural regions often drive summer blooms of toxic cyanobacteria. Aluminum sulfate (alum) applications are commonly used to control cyanobacteria blooms and restore water quality in eutrophic lakes. However, studies of alum treatments often lack true replication, comparison to reference lakes, or comparison to other restoration techniques, such as an alum and biomanipulation combined or “dual” treatments. Without these comparisons, the variation of treatment response between replicate lakes and restoration techniques remains uncertain. Therefore, I sought to assess how water quality is affected by multiple restoration techniques among geographically proximate (1.4 km²) …

Vagal Nerve Stimulation Therapy: What Is Being Stimulated?, Guy Kember, Jeffrey L. Ardell, John A. Armour, Mair Zamir

ETSU Faculty Works

Vagal nerve stimulation in cardiac therapy involves delivering electrical current to the vagal sympathetic complex in patients experiencing heart failure. The therapy has shown promise but the mechanisms by which any benefit accrues is not understood. In this paper we model the response to increased levels of stimulation of individual components of the vagal sympathetic complex as a differential activation of each component in the control of heart rate. The model provides insight beyond what is available in the animal experiment in as much as allowing the simultaneous assessment of neuronal activity throughout the cardiac neural axis. The results indicate …

Student Learning Outcomes Poster Session For Csb/Sju Joint Board Of Trustees Meeting, December 5th, 2014, Pamela L. Bacon, Bret Benesh, Carie Braun, Brian Campbell, Theresa Johnson, Jeanne Cofell, Catherine Bohn-Gettler, Janean Kleist, Michelle Li-Kuehne, Barbara May, Janna Lafountaine, Megan Lampel, Zainab Oke, Emily Schroeder, Katherine Thao, Anya Winkler, Sanford L. Moskowitz, Lisa M. Lindgren, Charles W. Wright, Abraham Lauer, Joshua St. George, Bryan Van Der Heiden

Office of Academic Review and Curricular Advancement Staff Publications

A faculty and student poster session was held focusing on student learning outcomes at the December 5^th, 2014 joint Board of Trustee meeting. The posters focused on using assessment of student learning to improve teaching and learning and covered student learning outcomes at the course, departmental, and institutional levels.

Challenges And Considerations In Optimizing Ovarian Stimulation Protocols In Oncofertility Patients, Kathryn Coyne, Mackenzie Purdy, Kathleen O'Leary, Jerome L. Yaklic, Steven R. Lindheim, Leslie A. Appiah

Obstetrics and Gynecology Faculty Publications

The scope of cancer treatment in women of childbearing age has changed in the last decade. Fertility preservation is no longer an afterthought but central to multi-disciplinary cancer treatment planning and should be addressed due to the cytotoxic effects of cancer therapy. However, oncology patients present as a unique treatment challenge as the physician must balance the urgency of fertility preservation with the risks of delaying cancer therapy. Controlled ovarian stimulation (COS) is routinely applied in assisted reproductive technology but can be contraindicated in women with estrogen-receptor-positive tumors. This paper reviews some of the challenges to consider when using COS …

Use Of Mobility Devices In Developing Countries; A Comparative Literature Review Introducing The Contextual Factors Surrounding Accessibility And Use Of Mobility Devices In Ghana, Bangladesh, And Guatemala., Bethany Shadel

Honors Theses

Disability in the developing world encompasses 10% of the global population and much of that population requires the use of a mobility device in order to engage in meaningful occupation. The use and accessibility of mobility devices is shaped by the significance of the barriers surrounding mobility. This research looks comparatively at the factors affecting accessibility and the use of mobility devices in three developing countries; Ghana, Bangladesh, and Guatemala. Trends within literature revealed that economic, environmental, and cultural barriers all had an impact on accessibility. Overall, this study determines that accessibility solutions are not possible without removing barriers to …

Ms171: Interview With Margaret Kripke, Margaret Kripke Ph.D., Houston Academy Of Medicine-Texas Medical Center Library

Texas Medical Center - Women's History Project

An oral history interview with Margaret Kripke. See more at Texas Medical Center-Women's History Project and its finding aid.

Ms171: Interview With Patricia Starck, Patricia Starck Ph.D., R.N., F.A.A.N., Houston Academy Of Medicine-Texas Medical Center Library

Texas Medical Center - Women's History Project

An oral history interview with Patricia Starck. See more at Texas Medical Center-Women's History Project and its finding aid.

The New Hampshire, Vol. 104 [105], No. 22 (Dec. 5, 2014), The New Hampshire

The New Hampshire Print Edition

An independent student produced newspaper from the University of New Hampshire. This volume was printed as 104, but it is the 105th volume in the series. This was corrected in pencil.

Learning To Give A Hoot: Open Access Workflows For Academic Librarians (Oawal), Jill Emery

Library Faculty and Staff Publications and Presentations

Graham Stone and Jill Emery have been working to try to develop an outline of some of the best practices for managing open access workflow management in academic libraries. In March 2014, we went live with OAWAL (pronounced owl): a crowdsourced blog/wiki to develop some of these practices and learn what innovators and experts in the field of scholarly communications and open access management have been doing. Our project is international in scope and relies heavily on countries such as the UK where country mandates are driving the development of workflows and management tools. This presentation will focus on recent …

Development And Mental Health Care Services: A Case Study At Rtccd, Hanoi, Michelle Lafortune

Independent Study Project (ISP) Collection

Vietnam’s rapid development since 1986 has had both positive and negative impacts on Vietnam’s mental health services. A health system was put into place and is expanding to overcome many challenges. Conversely, development has also brought with it new amenities and technologies that, in some cases, are being abused – one such is example is video games. As Vietnam deals with disturbing violent video game related episodes, parents and community members are searching for answers. This study project focuses on understanding the mental health care system in Vietnam and its current growth and advances. Three weeks were spent in Hanoi, …

Mandatory Arrest Policy Implications And Domestic Violence, Stephanie Smith

Honors Theses

I chose to do my honors thesis on the mandatory arrest policy regarding domestic violence. I will explore the history of domestic violence, the theoretical and ideological underpinnings of the policy, the research evidence that has been put forth regarding the policy and then offer my critical evaluation regarding the topic.