Digital Commons Network^™

P53 And Cancer-Associated Sialylated Glygans Are Surrogate Markers Of Cancerization Of The Bladder Associated With Schistosoma Haematobium Infection, Julio Santos, Elisabete Fernandes, Jose Alexandre Ferreira, Luis Lima, Ana Tavares, Andreia Peixoto, Beatriz Parreira, Jose Manuel Correia Da Costa, Paul J. Brindley, Carlos Lopes, Lucio L. Santos

Microbiology, Immunology, and Tropical Medicine Faculty Publications

Background

Bladder cancer is a significant health problem in rural areas of Africa and the Middle East where Schistosoma haematobium is prevalent, supporting an association between malignant transformation and infection by this blood fluke. Nevertheless, the molecular mechanisms linking these events are poorly understood. Bladder cancers in infected populations are generally diagnosed at a late stage since there is a lack of non-invasive diagnostic tools, hence enforcing the need for early carcinogenesis markers.

Methodology/Principal Findings

Forty-three formalin-fixed paraffin-embedded bladder biopsies of S. haematobium-infected patients, consisting of bladder tumours, tumour adjacent mucosa and pre-malignant/malignant urothelial lesions, were screened for bladder …

Procrastination And The College Student: An Analysis On Contributing Factors And Academic Consequences, Jourdan Ford

Education Undergraduate Research

No abstract provided.

Fit To Focus: Measuring The Effects Of Physical Activity On Behavior Management, Kaylee Vaughan

Education Undergraduate Research

No abstract provided.

Adaptations For The Introvert Personality: Perceptions Of Fifth-Grade Students, Gerald Lee Tary Ii

Education Undergraduate Research

No abstract provided.

The Public Health Exposome: A Population-Based, Exposure Science Approach To Health Disparities Research, Paul D. Juarez, Patricia Matthews-Juarez, Darryl B. Hood, Wansoo Im, Robert S. Levine, Barbara J. Kilbourne, Michael A. Langston, Mohammad Z. Al-Hamdan, William L. Crosson, Maurice G. Estes, Sue M. Estes, Vincent K. Agboto, Paul Robinson, Sacoby Wilson, Maureen Y. Lichtveld

Sociology Faculty Research

The lack of progress in reducing health disparities suggests that new approaches are needed if we are to achieve meaningful, equitable, and lasting reductions. Current scientific paradigms do not adequately capture the complexity of the relationships between environment, personal health and population level disparities. The public health exposome is presented as a universal exposure tracking framework for integrating complex relationships between exogenous and endogenous exposures across the lifespan from conception to death. It uses a social-ecological framework that builds on the exposome paradigm for conceptualizing how exogenous exposures “get under the skin”. The public health exposome approach has led our …

The Principle Of Reciprocity In Hospitality Contexts: The Relationship Between Tipping Behavior And Food Servers’ Approaches To Handling Leftovers, John S. Seiter, Harry Weger

Languages, Philosophy, and Communication Studies Faculty Publications

Based on the norm of reciprocity, this study hypothesized that food servers would earn higher tips when they boxed customers’ leftovers compared to having customers box leftovers themselves. In addition, the effect of writing messages (i.e., the date and/or customer’s name) on boxes of leftovers was explored. Two female food servers waited on 608 diners and boxed or did not box leftovers, and wrote or did not write messages on boxes. The hypothesis was supported. However, writing messages was not associated with tipping behavior.

Examination Of Capital Murder Jurors’ Deliberations: Methods And Issues, Keith Price, Susan Coleman, Gary R. Byrd

Administrative Issues Journal

The study of capital juries remains a subject of critical interest for the public and for legislative and judicial policy makers as well as legal scholars and social scientists. Cowan, Thompson, and Ellsworth established one of the standard methodologies for examination of this topic in their 1984 seminal study by observing the subjects’ debate about conviction in a death penalty case utilizing mock juries; other scholars employed different techniques to add more information in the late 1990s. Yet, the question of death qualification and prosecutorial bias remains open to inquiry. This preliminary study found evidence to support bias toward conviction …

College Senate Minutes December 11, 2014, Bronx Community College Senate

BCC Governance Archives

No abstract provided.

Regulation Of Three Nitrogenase Gene Clusters In The Cyanobacterium Anabaena Variabilis Atcc 29413, Teresa Thiel, Brenda Pratte

Biology Department Faculty Works

The filamentous cyanobacterium Anabaena variabilis ATCC 29413 fixes nitrogen under aerobic conditions in specialized cells called heterocysts that form in response to an environmental deficiency in combined nitrogen. Nitrogen fixation is mediated by the enzyme nitrogenase, which is very sensitive to oxygen. Heterocysts are microxic cells that allow nitrogenase to function in a filament comprised primarily of vegetative cells that produce oxygen by photosynthesis. A. variabilis is unique among well-characterized cyanobacteria in that it has three nitrogenase gene clusters that encode different nitrogenases, which function under different environmental conditions. The nif1 genes encode a Mo-nitrogenase that functions only in heterocysts, …

The Effect Of Teaching 3rd Grade Students New Strategies To Raise Math Assessment Scores: An Emphasis On Addition And Subtraction, Tracy Strong

Education Undergraduate Research

No abstract provided.

A Comparison Of Stability Balls Versus Chairs In The Classroom: Student Preferences And Effects On Classroom Management, Erin Messinger

Education Undergraduate Research

No abstract provided.

Exploring The Intersection Between Folk And Conventional Medicine In Albany, Kentucky, Chloe J. Brown

Mahurin Honors College Capstone Experience/Thesis Projects

Approximately 60% of patients surveyed (in Albany, KY) practice folk medicine, which suggests that a significant segment of the population may practice folk medicine. Patients typically use folk medical treatments concurrently with conventional medical treatments; while the interaction of these treatments is generally innocuous or positive, folk medical treatments can sometimes be harmful, lead to negative interactions with other drugs prescribed by a conventional medical professional. Since folk medicine and conventional medicine frequently interact, it is important for medical professionals to be aware of and address folk medical practices in a conventional medical environment. In order to better address folk …

Hip Fracture Evaluation With Alternatives Of Total Hip Arthroplasty Versus Hemiarthroplasty (Health): Protocol For A Multicentre Randomised Trial, Mohit Bhandari, P. J. Devereaux, Thomas A. Einhorn, Lehana Thabane, Emil H. Schemitsch, Kenneth J. Koval, Frede Frihagen, Rudolf W. Poolman, Kevin Tetsworth, Ernesto Guerra-Farfán, Kim Madden, Sheila Sprague, Gordon Guyatt, Ali Oliasharazi, Franklin D. Shuler, Jonathon Salva, James Day, Tigran Garabekyan, Felix Cheung, Linda Morgan, Timothy Wilson-Byrne Md, Mary Beth Cordle

Orthopaedics

Introduction: Hip fractures are a leading cause of mortality and disability worldwide, and the number of hip fractures is expected to rise to over 6 million per year by 2050. The optimal approach for the surgical management of displaced femoral neck fractures remains unknown. Current evidence suggests the use of arthroplasty; however, there is lack of evidence regarding whether patients with displaced femoral neck fractures experience better outcomes with total hip arthroplasty (THA) or hemiarthroplasty (HA). The HEALTH trial compares outcomes following THA versus HA in patients 50 years of age or older with displaced femoral neck fractures.

Methods and …

Spatial Variation In The Littoral Vertebrate Community Of A Reservoir Relative To Physical And Biological Gradients, Nathan Ruhl, Jessica J. Soski, Willem M. Roosenburg

College of Science & Mathematics Departmental Research

Reservoirs possess gradients in conditions and resources along their long (deep-shallow) axis, but the response of littoral vertebrates (fish and turtles) to these gradients is poorly understood. We have quantified the littoral vertebrate communities throughout a small reservoir in Southeastern Ohio during July and August using traps, and related community composition to environmental variables using NMDS ordination. Ordination revealed that fish and turtles were broadly separated in ordination space, and three distinctly different environmental gradients were significantly associated with the underlying observed species abundances. Observed turtle abundance was explained by measurements of bathymetry, turbidity, and benthic resources, but none of …

Graduate Teaching Assistants: Responding To The Challenges Of Internationalisation, Jennie Winter, Rebecca Turner, Sharon Gedye, Patricia Nash, Vivien Grant

Plymouth Institute of Education

The last decade has seen intensification in moves to professionalise the practice of university teaching, including graduate teaching assistants (GTAs). It has also seen significant growth in terms of the internationalisation of the postgraduate student body and changing expectations around doctoral training. These transformations have implications for the construction, delivery, and management of educational training for this group, yet little contemporary research exists investigating the adaptability of academic development and institutions to such change. This paper reports empirical research exploring these issues using a UK-based case study. The research investigated the international doctoral students’ experience of a teaching course and …

Transceptors At The Boundary Of Nutrient Transporters And Receptors: A New Role For Arabidopsis Sultr1;2 In Sulfur Sensing, Zheng Zhiliang, Bo Zheng, Thomsa Leustek

Publications and Research

Plants have evolved a sophisticated mechanism to sense the extracellular sulfur (S) status so that sulfate transport and S assimilation/metabolism can be coordinated. Genetic, biochemical, and molecular studies in Arabidopsis over the past 10 years have started to shed some light on the regulatory mechanism of the S response. Key advances in transcriptional regulation (SLIM1, MYB, and miR395), involvement of hormones (auxin, cytokinin, and abscisic acid) and identification of putative sensors (OASTL and SULTR1;2) are highlighted here. Although our current view of S nutrient sensing and signaling remains fragmented, it is anticipated that through further studies a sensing and signaling …

Family-Of-Origin Characteristics Of Men Who Engage Regularly In Sexually Addictive Behavior, Mark Stephen Pfuetze

Dissertations

The present study surveyed men to assess whether any correlations existed between a man’s sexually addictive behavior and how his family-of-origin addressed sexuality along with demographic factors. A total of 374 male participants (18 years or older) provided complete data sets via the online survey located on SurveyMonkey. The main research question for this study was as follows: Is there a relationship between demographic variables or family factors: (a) negative attitudes and communication about sexuality in one’s family-of-origin, (b) exposure to sexual stimuli in one’s family-of-origin, and (c) open sexual discussion in one’s family-of-origin, and sexual addiction. All three of …

Dbc1/Ccar2 And Ccar1 Are Largely Disordered Proteins That Have Evolved From One Common Ancestor, Jessica Brunquell, Jia Yuan, Aqeela Erwin, Sandy D. Westerheid, Bin Xue

Molecular Biosciences Faculty Publications

Deleted in breast cancer 1 (DBC1, CCAR2, KIAA1967) is a large, predominantly nuclear, multidomain protein that modulates gene expression by inhibiting several epigenetic modifiers, including the deacetylases SIRT1 and HDAC3, and the methyltransferase SUV39H1. DBC1 shares many highly conserved protein domains with its paralog cell cycle and apoptosis regulator 1 (CCAR1, CARP-1). In this study, we examined the full-length sequential and structural properties of DBC1 and CCAR1 from multiple species and correlated these properties with evolution. Our data shows that the conserved domains shared between DBC1 and CCAR1 have similar domain structures, as well as similar patterns of predicted disorder …

Jane Austen And The 21st-Century Classroom, Maureen Jecrois

Honors Program Theses and Projects

Across the United States, educators and administrators have been discussing whether classical literature still has a place within the high school classroom. Included in this discussion are the works of Jane Austen. And while Jane Austen’s texts have much to offer as far as discussion on gender and familial dynamics, economic and political tension, and, of course, societal norms (what our communities expect from us individually and as a whole), the texts present many challenges within the frameworks of today’s classroom. What we have come to know as “our” time is a rapidly changing environment filled with experiences and technologies …

Tall Fescue Seed Extraction And Partial Purification Of Ergot Alkaloids, Huihua Ji, Franklin Fannin, J. Klotz, Lowell P. Bush

Kentucky Tobacco Research and Development Center Faculty Publications

Many substances in the tall fescue/endophyte association (Schedonorus arundinaceus/Epichloë coenophiala) have biological activity. Of these compounds only the ergot alkaloids are known to have significant mammalian toxicity and the predominant ergot alkaloids are ergovaline and ergovalinine. Because synthetically produced ergovaline is difficult to obtain, we developed a seed extraction and partial purification protocol for ergovaline/ergovalinine that provided a biologically active product. Tall fescue seed was ground and packed into several different sized columns for liquid extraction. Smaller particle size and increased extraction time increased efficiency of extraction. Our largest column was a 114 × 52 × …

An Evidence-Based Approach To A Replacement Hospital Training Curriculum, Mark D. Beck

Doctor of Nursing Practice (DNP) Projects

Creation of a training and educational curriculum for a new or replacement facility is daunting in its own right, but without a repository of organizational knowledge cataloging the transfer of tacit to explicit knowledge from the organizations previous library of facility openings, the task becomes Herculean, with as many tasks and cast of characters as the original myths. Navigating the shoals, eddies and tides of the various aspects of this project revealed the need for a comprehensive knowledge management solution to training that is coupled with healthcare design principles and initiatives. This purpose of the DNP project is about the …

Moral Anxiety, Mortal Terror: Considering Spielberg, Post-9/11, Jake T. Bart

Cinesthesia

In the wake of 9/11, a defining moment in the young 21st century, Spielberg’s thematic concerns undergo a marked evolution. As film historian Joseph McBride noted, “(n)o other American artist confronted the key events of the first decade of the century with such sustained and ambitious treatment” (450). Together, Spielberg’s War of the Worlds (2005), Munich (2005), and Minority Report (2002) create an informal trilogy, each exploring a different facet of American shock and anxiety in the War on Terror era.

Seven Faculty Awarded Emeritus Status, Natalie Wade

Browse All News

No abstract provided.

Daily Eastern News: December 11, 2014, Eastern Illinois University

December

No abstract provided.

Stochastic Adaptive Event-Triggered Control And Network Scheduling Protocol Co-Design For Distributed Networked Systems, Hao Xu, Avimanyu Sahoo, Sarangapani Jagannathan

Electrical and Computer Engineering Faculty Research & Creative Works

In a distributed 'networked control system' (NCS), multiple physical systems or agents are connected to their corresponding controllers through a shared packet-switched communication network. For such distributed NCS, periodic sampled controller design is unsuitable to handle packet-switched closed-loop control systems, and a novel stochastic optimal adaptive event-sampled controller scheme is proposed in the application layer for each physical system or agent expressed as an uncertain linear dynamic system. Lyapunov stability analysis will be utilized to derive the event trigger condition. In addition, a network scheduling protocol is also required for such NCS. Traditional network scheduling protocols are unsuitable for such …

Lack Of Medicaid Funding For Occupational Therapy Serving The Autism Spectrum Disorder Population Ages 0-5 Years, Mary O'Donohue

Honors Theses

The prevalence of autism in the United States is currently 1 in 68 children (Autism Alliance of Michigan, 2014). This is considered an epidemic. There are a variety of treatments available in the state of Michigan for children with autism, such as occupational therapy, speech therapy, physical therapy, and applied behavior analysis (ABA). Effective April 1^st, 2013, Michigan increased their funding cap for ABA therapy for treating children with autism. However, there is a lack of knowledge within the community and amongst professionals in regards to the critical treatment occupational therapy practitioners provide and as a result, there …

A Critical Analysis Of Infant Mortality In Kalamazoo County, Audrey Jensen

Honors Theses

The following is a review of the state of infant and fetal health in Kalamazoo County in the 21st century. Since infant health is a marker for the effectiveness of health care, this review will analyze the leading causes of infant mortality in Kalamazoo County. Statistical indicators show that Kalamazoo County falls below both state and national IMR averages. The leading causes of infant mortality in Kalamazoo are considered preventable infant deaths. Therefore, this review will make recommendations for the reduction of IMR through the improvement of preventative prenatal healthcare practices.

Identifying Professional Development Opportunities For Remote Healthcare Interpreters On A Shared Network, Suzanne M. Couture

Instructional Design Capstones Collection

Many healthcare organizations are faced with the challenge of complying with an unfunded mandate to provide language services free of charge to individuals with limited English proficiency or those who are deaf or hard of hearing. One method of increasing efficiencies and reducing disparities for these vulnerable populations is to provide access to remote audio/video interpreters on a shared network. The Health Care Interpreter Network (HCIN) is a non-profit organization based in California that comprises more than forty member hospitals and offers service in twenty languages. To support the need for on-going professional development of HCIN’s interpreters, a front-end analysis …

The Birds Of Genome10k, Stephen J. O'Brien, David Haussler, Oliver A. Ryder

Biology Faculty Articles

Everyone loves the birds of the world. From their haunting songs and majesty of flight to dazzling plumage and mating rituals, bird watchers – both amateurs and professionals - have marveled for centuries at their considerable adaptations. Now, we are offered a special treat with the publication of a series of papers in dedicated issues of Science, Genome Biology and GigaScience (which also included pre-publication data release). These present the successful beginnings of an international interdisciplinary venture, the Avian Phylogenomics Project that lets us view, through a genomics lens, modern bird species and the evolutionary events that produced them.

Navy, Russian (1991-), Bert Chapman

Libraries Faculty and Staff Scholarship and Research

Provides a historical overview and analysis of events affecting the Russian Navy from 1991-present. Emphasizes how this force still has mammoth strategic ambitions despite limited resources and an obsolete infrastructure. Stresses the ongoing presence of nuclear weapons, the increasing importance of the Northern Sea Route in Russian and international trade and strategy, and how U.S. and NATO countries budget constraints may make it hard for them to resist Russian assertiveness in areas such as Ukraine.