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2014

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High-Performance Meta-Genomic Gene Identification, Ibrahim Savran Dec 2014

High-Performance Meta-Genomic Gene Identification, Ibrahim Savran

Theses and Dissertations

Computational Genomics, or Computational Genetics, refers to the use of computational and statistical analysis for understanding the structure and the function of genetic material in organisms. The primary focus of research in computational genomics in the past three decades has been the understanding of genomes and their functional elements by analyzing biological sequence data. The high demand for low-cost sequencing has driven the development of highthroughput sequencing technologies, next-generation sequencing (NGS), that parallelize the sequencing process, producing thousands or millions of sequences concurrently. Moore’s Law is the observation that the number of transistors on integrated circuits doubles approximately every two …

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A Soul Composed Of Harmonies: George Herbert's Life, Writings, And Choral Settings Of His English Poetry, Benjamin Todd Ebner Dec 2014

A Soul Composed Of Harmonies: George Herbert's Life, Writings, And Choral Settings Of His English Poetry, Benjamin Todd Ebner

Theses and Dissertations

George Herbert’s poetry is among the greatest religious poetry written in the English language. His introspective and nuanced understanding of the human soul and his beautiful style of writing have earned him his place among the great poets. His catalogue is filled with poems ready to be set to music, and dozens of them have been. However, there is no document that seeks to gather an annotated list of these compositions in one place. Further, while a few of these compositions are performed often, there are dozens of other worthy compositions that should be heard on a more wide and …

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Innovation Among Georgian Journalism Educators: A Network Analysis Perspective, Ana Keshelashvili Dec 2014

Innovation Among Georgian Journalism Educators: A Network Analysis Perspective, Ana Keshelashvili

Theses and Dissertations

Rapid developments in technology in recent years have disrupted the media’s traditional role as a main informer for citizens. The changes have challenged journalism educators worldwide, pushing them to innovate and experiment. One purpose of this dissertation is to examine adoption of innovations by journalism educators in Georgia, a small post-Soviet country with partly free media and lack of professional outlets, that has been and still is a beneficiary of Western aid for media development. Employing innovation diffusion theory and the network analysis perspective, this dissertation uses a census of journalism educators and journalism program leaders in Georgia to understand …

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Novel Biofabrication Technologies To Recapitulate In Vivo Geometries In Collagen Hydrogels, Veronica Rodriguez-Rivera Dec 2014

Novel Biofabrication Technologies To Recapitulate In Vivo Geometries In Collagen Hydrogels, Veronica Rodriguez-Rivera

Theses and Dissertations

Tissue engineering and regenerative medicine aims to restore form and function to tissues that have been lost or damaged due to disease, congenital defect, or trauma. Biomaterials suitable to restore these complex tissues need to provide a balance between chemical and mechanical properties, providing accurate cell-matrix interaction and induce in vivo behaviors such as proliferation, differentiation and migration. It also requires that physical and chemical cues be presented to the body in the proper temporal and spatial pattern. The extracellular matrix exerts forces that are transmitted through focal adhesion causing changes in the cell behavior. The hypothesis for this dissertation …

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Low Reynolds Number Turbulence: Mechanisms And Applications, Wei Zhao Dec 2014

Low Reynolds Number Turbulence: Mechanisms And Applications, Wei Zhao

Theses and Dissertations

Turbulence, as one of "the most important unsolved classical problem in physics" (R. Feynman, 1932), has been investigated for more than 130 years. Conventionally, turbulence is believed to be a phenomenon of high Reynolds numbers (Re). However, we find that turbulence can also be achieved at low Re by proper external forcing, either in macroflows or in microflows. In macroflows, the characteristics of high Re turbulence can be achieved in confined flows, when the bulk flow Re is around 400, by external forcing at its optimal frequency (Wang 2003; Wang 2006). Interestingly, the optimal narrow band of frequency is fixed …

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Surface Modification Of Nanoplatelets In Polymer Nanocomposites, Shailesh K. Shori Dec 2014

Surface Modification Of Nanoplatelets In Polymer Nanocomposites, Shailesh K. Shori

Theses and Dissertations

In polymer nanocomposites (PNCs), it is very important that the nanofiller (typically an inorganic) is well-dispersed in an organic polymer matrix. Optimal compatibility results in end-use products such as packaging materials with enhanced properties. In practice, however, this is challenging to achieve because “ideal” dispersions require the complete uniform separation, termed exfoliation, of the nanofiller within the matrix. As a result, different nanofillers including calcium niobate (CN) and montmorillonite (MMT) are first studied for their ability to exfoliate in aqueous suspensions by measuring the organic cation uptake. The cation exchange capacity, or CEC, determined that CN needs further work before …

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Applications Of Advanced Imaging Methods: Macro-Scale Studies Of Woven Composites And Micro-Scale Measurements On Heated Ic Packages, Siming Guo Dec 2014

Applications Of Advanced Imaging Methods: Macro-Scale Studies Of Woven Composites And Micro-Scale Measurements On Heated Ic Packages, Siming Guo

Theses and Dissertations

As a representative advanced imaging technique, the digital image correlation (DIC) method has been well established and widely used for deformation measurements in experimental mechanics. This methodology, both 2D and 3D, provides qualitative and quantitative information regarding the specimen’s non-uniform deformation response. Its full-field capabilities and non-contacting approach are especially advantageous when applied to heterogeneous material systems such as fiber-reinforced composites and integrated chip (IC) packages. To increase understanding of damage evolution in advanced composite material systems, a series of large deflection bending-compression experiments and model predictions have been performed for a woven glass-epoxy composite material system. Stereo digital image …

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Practical Concurrency Support For Web Service Transactions, Emad Alsuwat Dec 2014

Practical Concurrency Support For Web Service Transactions, Emad Alsuwat

Theses and Dissertations

Traditional database concurrency control methods use locking, timestampordering, and optimistic-ordering to achieve DB consistency. However, these approaches are not suitable for long-running Web Service Compositions (WSCs) due to associated performance degradation. Our hypothesis asserts that, using transactional semantic and ordering information, the execution time of a WSC can be reduced, thus allowing the use of traditional database concurrency control methods while avoiding unacceptable performance degradation. Our solution is based on the following approaches: § We model a WSC as WS-BPEL specification, i.e., a partial order of WS transactions. § We allow some of the WS transactions in the WSC to …

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A Three-Dimensional-Engineered Matrix To Study The Microenvironment Of Cancer Stem Cells, Samaneh Kamali Sarvestani Dec 2014

A Three-Dimensional-Engineered Matrix To Study The Microenvironment Of Cancer Stem Cells, Samaneh Kamali Sarvestani

Theses and Dissertations

Maintenance of cancer stem cells (CSCs) is regulated by their microenvironment. As cancer cells are affected by many factors in their microenvironment, a major challenge is to isolate the effect of a specific factor on CSCs while keeping other factors unchanged. We developed a synthetic inert 3D Poly Ethylene Glycol Di-Acrylate (PEGDA) gel culture system as a unique tool to study the effect of microenvironmental factors on CSCs response. Synthetic hydrogels provide the flexibility to design three-dimensional (3D) matrices to isolate and study individual factors in the tumor microenvironment. The first objective of this work was to investigate the effect …

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Automatic Loop Tuning And Memory Management For Stencil Computations, Fan Zhang Dec 2014

Automatic Loop Tuning And Memory Management For Stencil Computations, Fan Zhang

Theses and Dissertations

The Texas Instruments C66x Digital Signal Processor (DSP) is an embedded processor technology that is targeted at real time signal processing. It is also developed with a high potential to become the new generation of coprocessor technology for high performance embedded computing. Of particular interest is its performance for stencil computations, such as those found in signal processing and computer vision tasks. A stencil is a loop in which the output value is updated at each position of an array by taking a weighted function of its neighbors. Efficiently mapping stencil-based kernels to the C66x device presents two challenges. The …

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Semiparametric Regression Analysis Of Bivariate Interval-Censored Data, Naichen Wang Dec 2014

Semiparametric Regression Analysis Of Bivariate Interval-Censored Data, Naichen Wang

Theses and Dissertations

Survival analysis is a long-lasting and popular research area and has numerous applications in all fields such as social science, engineering, economics, industry, and public health. Interval-censored data are a special type of survival data, in which the survival time of interest is never exactly observed but is known to fall within some observed interval. Interval-censored data arise commonly in real-life studies, in which subjects are examined at periodical or irregular follow-up visits. In this dissertation, we develop efficient statistical approaches for regression analysis of bivariate intervalcensored data, in which the two survival times of interest are correlated and both …

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Experimental And Theoretical Studies Of Native And Engineered Vascular Tissue Mechanics, Boran Zhou Dec 2014

Experimental And Theoretical Studies Of Native And Engineered Vascular Tissue Mechanics, Boran Zhou

Theses and Dissertations

Background: Implantation of vascular grafts provides a means to restore blood flow in compromised regions of the circulatory system, and thus is used to treat a wide range of cardiovascular diseases. Despite significant advancements in autologous grafting strategies as well as the engineering of synthetic alternatives, mechanical, structural, and compositional incongruities between the graft and the host artery remain as contributing factors to graft failure. The typical failure modality manifests as proximal anastomotic intimal hyperplasia, which places restrictions on the host vessel size currently treated with grafting strategies (> 5 mm internal diameter). In order to improve long-term clinical outcomes, …

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Bio-Active Degradable Micellar Hydrogels For Osteogenic Differentiation Of Mesenchymal Stem Cells, Seyedsina Moeinzadeh Dec 2014

Bio-Active Degradable Micellar Hydrogels For Osteogenic Differentiation Of Mesenchymal Stem Cells, Seyedsina Moeinzadeh

Theses and Dissertations

A feasible approach to the restoration of injured bone tissue is the use of tissue engineering strategies to deliver mesenchymal stem cells (MSCs) to the site of regenration in degradable, in-situ gelling, bio-active hydrogels. Although inert Polyethylene glycol (PEG) hydrogels provide flexibility in controlling the cell microenvironment, their use for in vivo applications in tissue regeneration is limited by their persistence (nondegradability) in the site of regeneration. In an attempt to produce inert hydrolytically degradable matrices for encapsulation of MSCs, hydrogels based on star PEG macromonomers chain-extended with short hydroxy acid (HA) segments (SPEXA) were synthesized and characterized with respect …

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Automated Scratchpad Mapping And Allocation For Embedded Processors, Yang Gao Dec 2014

Automated Scratchpad Mapping And Allocation For Embedded Processors, Yang Gao

Theses and Dissertations

Embedded system-on-chip processors such as the Texas Instruments C66 DSP and the IBM Cell provide the programmer with a software controlled on-chip memory to supplement a traditional but simple two-level cache. By decomposing data sets and their corresponding workload into small subsets that fit within this on-chip memory, the processor can potentially achieve equivalent or better performance, power efficiency, and area efficiency than with its sophisticated cache. However, program controlled on chip memory requires a shift in the responsibility for management and allocation from the hardware to the programmer. Specifically, this requires the explicit mapping of program arrays to specific …

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Theoretical Investigation Of The Catalytic, Liquid-Phase Hydrodeoxygenation Of Organic Acids And Esters, Sina Behtash Dec 2014

Theoretical Investigation Of The Catalytic, Liquid-Phase Hydrodeoxygenation Of Organic Acids And Esters, Sina Behtash

Theses and Dissertations

With worldwide fossil fuel resources dwindling and greenhouse gas emissions rising, it is urgent to find renewable liquid fuel alternatives from e.g. biomass to meet the world’s growing energy demand. Lipid feedstocks and pyrolysis oils from woody biomass can be utilized for the production of second-generation biofuels via a catalytic hydrodeoxygenation (HDO) process. The conversion of fatty acids and esters plays an important role in the activity and selectivity of these processes. Understanding the HDO reaction mechanism of organic acids and esters on metal surfaces is a prerequisite for the rational design of new HDO catalysts specifically designed for upgrading …

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Benefits Of Video Games In Multidisciplinary Scientific Research, Jeremiah Jeffrey Shepherd Dec 2014

Benefits Of Video Games In Multidisciplinary Scientific Research, Jeremiah Jeffrey Shepherd

Theses and Dissertations

In recent years, computer-based games have been shown to be effective both as a tool for conducting research in a variety of domains and for research on games itself. In this work, we show that implementing games that have a basis in theory and that are combined with the most recent gaming practices result in effective research tools. We demonstrate this via game implementations for three domains. The first implementation is based on new theories in speech pedagogy, and demonstrates the effectiveness of our approach. The second implementation shows that using a game that simulates therapeutic speech practices can aid …

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Behavior Of Piezoelectric Wafer Active Sensor In Various Media, Tuncay Kamas Dec 2014

Behavior Of Piezoelectric Wafer Active Sensor In Various Media, Tuncay Kamas

Theses and Dissertations

The dissertation addresses structural health monitoring (SHM) techniques using ultrasonic waves generated by piezoelectric wafer active sensors (PWAS) with an emphasis on the development of theoretical models of standing harmonic waves and guided waves. The focal objective of the research is to extend the theoretical study of electro-mechanical coupled PWAS as a resonator/transducer that interacts with standing and traveling waves in various media through electro-mechanical impedance spectroscopy (EMIS) method and guided wave propagation. The analytical models are developed and the coupled field finite element analysis (CF-FEA) models are simulated and verified with experiments. The dissertation is divided into two parts …

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Task-Specific Human Capital Accumulation And Wage Outcomes Among Young Men: An Empirical Analysis, Morgan Holland Dec 2014

Task-Specific Human Capital Accumulation And Wage Outcomes Among Young Men: An Empirical Analysis, Morgan Holland

Theses and Dissertations

Existing literature suggests that investment in different kinds of task-specific human capital may have significant effects on wage outcomes and overall economic wellbeing of individuals. To examine this claim, the accumulation of task-specific human capital in young male workers with no college education and its effects on wages is measured. Using National Longitudinal Survey of Youth panel data merged with six task-specific human capital measures derived from the Dictionary of Occupational Titles task contents data, fixed effects regression was utilized to measure how workers’ taskspecific human capital develops over time. This process shows that among the task measures used, accumulation …

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Quantifying Individual Losses In A Direct Methanol Fuel Cell, Jennifer Rae Ruffing Dec 2014

Quantifying Individual Losses In A Direct Methanol Fuel Cell, Jennifer Rae Ruffing

Theses and Dissertations

The performance of a direct methanol fuel cell (DMFC) is complicated due to the complex interactions of kinetic and transport processes. As a result, changes in one aspect of the cell have consequences in other aspects, which are difficult to elucidate from the full-cell polarization (i.e. voltage vs. current) behavior that fuel cell researchers often use to characterize the performance of their systems. The objective of this work was to develop a strategy to use current and voltage relationships from anode half cells, cathode half-cells, and a hydrogen pump, coupled with methanol crossover data and a mathematical model, to quantify …

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Numerical Modeling Of Free Surface Flows Using Depth Averaged And 3d Models, Khaled Mamdouh Mohamed Abdo Dec 2014

Numerical Modeling Of Free Surface Flows Using Depth Averaged And 3d Models, Khaled Mamdouh Mohamed Abdo

Theses and Dissertations

The objectives of the research presented in this dissertation are to develop and apply numerical models to study free surface flows under different boundary conditions, bedform geometry and channel configuration. A 2D depth-averaged model is developed by solving the Saint Venant or the shallow water equations using a finite volume method. An existing 3D model, developed in-house, that solves the Reynoldsaveraged Navier-Stokes equations and conservation equations for suspended sediment and conservative species is adapted for free surface flows by solving the volume of fluid (VOF) equation using a compressive interface capturing scheme for arbitrary meshes, CICSAM. The depth-averaged or shallow …

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Context-Sensitive Seismic Strengthening And Repair Of Substandard Confined Masonry, Rahim Ghorbani Dec 2014

Context-Sensitive Seismic Strengthening And Repair Of Substandard Confined Masonry, Rahim Ghorbani

Theses and Dissertations

Confined masonry (CM) is a construction system consisting of load-bearing masonry panels that are confined with cast-in-place reinforced concrete tie columns and beams. Due to satisfactory seismic performance, CM has become the predominant low-rise residential construction system in several areas around the world. However, in developing regions, the use of substandard materials, details and construction practices may result in inadequate performance as highlighted in the 2010 earthquakes in Haiti and Chile. In the aftermath of an earthquake, households are often reluctant to reoccupy their dwellings due to concerns about safety of structures. If feasible, preventive (pre-hazard) strengthening or structural repair …

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Conflicted Union: Culture, Economics And European Union Media Policy, Daphney Pernola Barr Dec 2014

Conflicted Union: Culture, Economics And European Union Media Policy, Daphney Pernola Barr

Theses and Dissertations

The constant tension between internal market development and cultural preservation remain within European Union audiovisual media services regulatory policy. While market harmonization and liberalization are key to developing a formidable European media market, the preservation of and promotion of ‘European-ness’ depends upon the protection of cultural diversity, a necessity for a confederation of 27 sovereign nation-states with distinct cultures and languages. It may not currently be possible to reconcile the intrinsic duality of audiovisual media through EU regulatory policy mechanisms. However, a regulatory policy clearly that addresses the potential of cultural harmonization/economic liberalization conflict, that explicitly connects the EU’s audiovisual …

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Modeling Mussel Mortality: Investigating The Importance Of Swash And The Potential Implications Of Changing Wave Environments, Shadow Leigh Gulledge Dec 2014

Modeling Mussel Mortality: Investigating The Importance Of Swash And The Potential Implications Of Changing Wave Environments, Shadow Leigh Gulledge

Theses and Dissertations

Rising sea level and increases in temperature are causing biogeographic shifts in intertidal zones and can also lead to shifts in the local vertical zonation of organisms due to changes in body temperature during aerial exposure during low tide. Swash is an important determinant of aerial body temperatures, and vulnerability of intertidal zones to changes in climate could potentially depend on how much and how often animals are cooled by waves. While wave heights (and thus swash) are generally expected to increase with climate change, anthropogenic physical structures, such as breakwaters and wave energy converters, can decrease wave height and …

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Quantitative Comparison Of Time-Frequency Decomposed Gait Emg Signals, L. Patrick Mitchell Dec 2014

Quantitative Comparison Of Time-Frequency Decomposed Gait Emg Signals, L. Patrick Mitchell

Theses and Dissertations

Falls in the senior population represent an immediate threat to both current and future generations’ quality of life. The results of falls can be disastrous, create a long road to recovery, and in many cases result in death. Hypertension represents a difficult-to-quantify condition which is known to contribute to gait and balance dysfunction. Accurate assessment of conditions such as these represents an area of primary investigative need. In order to meet this need, a new experimental setup is developed which combines time-frequency analysis with surface electromyography (sEMG) signals obtained during ambulation. 3-bit pressure data is acquired using a pressure-sensitive mat, …

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Synthesis Of Au And Ag Catalysts With Controlled Sizes Of Metal Particles, Eleni A. Kyriakidou Dec 2014

Synthesis Of Au And Ag Catalysts With Controlled Sizes Of Metal Particles, Eleni A. Kyriakidou

Theses and Dissertations

The performance of supported metal catalysts largely depends on the structure and composition of the metal particles and the nature of the support. In order to achieve better control over these parameters, synthetic route based on the use of templating agents has been proposed. Among the different templating agents, poly(amidoamine) (PAMAM) dendrimers have attracted a lot of recent attention as nanoparticle stabilizers. In this thesis, Au/G4OH nanocomposites were synthesized in aqueous solutions and used as precursors for the preparation of SiO2-supported Au nanoparticles. Elemental analysis, UV-Vis, and STEM measurements were used to estimate the extent of the Au-dendrimer interactions and …

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An Engineering Approach For The Design Of Archaeological Reburial Systems, Angel Ari Perez Mejia Dec 2014

An Engineering Approach For The Design Of Archaeological Reburial Systems, Angel Ari Perez Mejia

Theses and Dissertations

Archaeological sites are a non-renewable resource which is often our only link to the past. However, sites are under constant threat of destruction due to construction activities. Civil engineers and archaeologists must the work together to ensure both the continued survival of archaeological sites while allowing for development to continue. Reburial systems, when properly designed and constructed, allow for the protection of archaeological sites while allowing the continued use of the land. However, because reburial as an intentional conservation technique is relatively modern, practice is fragmented and there are no universally accepted guidelines. Current reburial system design relies on prescriptive …

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'Precious Objects': Strange 'Things' In James And Wharton, John Kinard Dec 2014

'Precious Objects': Strange 'Things' In James And Wharton, John Kinard

Theses and Dissertations

In this work, I attempt to examine the importance of things, the strange agency of objects, which emerges in the literature of the late nineteenth century. To this end, I examine the economy of things in both Henry James and Edith Wharton. I attempt to connect this object agency with the emergent discourses and technologies of the time, and to link these both with media and queer theory.

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Cost Avoidance Analysis Of Military Aircraft Components Utilizing Condition-Based Maintenance Practices, Erin Ballentine Dec 2014

Cost Avoidance Analysis Of Military Aircraft Components Utilizing Condition-Based Maintenance Practices, Erin Ballentine

Theses and Dissertations

This research involves two major case studies. Both look at the current maintenance practices done by the United States Army and propose a solution for improvement utilizing condition-based maintenance (CBM) practices. Each study details a cost avoidance that can be earned by implementing the solutions and the resulting benefits that can be experienced. Case Study I is a return on investment (ROI) that analyzes the benefits of the implementation of elastomeric wedges as vibration control on the Apache (AH-64D) aircraft. Analysis of the material and operational costs shows that the use of self-adhering elastomeric trailing edge wedges on the Apache …

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On The Development Of High Strain Rate Experiments For The Characterization Of Engineering Materials, Silas P. Mallon Dec 2014

On The Development Of High Strain Rate Experiments For The Characterization Of Engineering Materials, Silas P. Mallon

Theses and Dissertations

In order to predict the damage accumulation and failure processes associated with highly dynamic events such as blast loading, shock wave loading, and ballistic impact loading, a commensurate understanding of the fundamental constitutive and fracture behavior of materials subjected to such high rate loading conditions is necessary. In this effort, high strain rate experimental facilities consisting of a shock tube apparatus and a torsional split Hopkinson bar apparatus have been designed, constructed, and subsequently used to investigate the mechanical properties of an array of engineering materials subjected to a variety of dynamic loading conditions. Designs for the experimental equipment utilized …

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Slow Wave Structures Integrated With Ferro-Magnetic And Ferro-Electric Thin Films For Smart Rf Applications, B M Farid Rahman Dec 2014

Slow Wave Structures Integrated With Ferro-Magnetic And Ferro-Electric Thin Films For Smart Rf Applications, B M Farid Rahman

Theses and Dissertations

Modern communications systems are following a common trend to increase the operational frequency, level of integration and number of frequency bands. Although 90-95% components in a cell phone are passives which take 80% of the total board area. High performance RF passive components play limited role and are desired towards this technological advancement. Slow wave structure is one of the most promising candidates to design compact RF and mm-Wave passive components. Slow wave structures are the specially designed transmission line realized by placing the alternate narrow and wide signal conductors in order to reduce the physical size of the components. …

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