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2014

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Size Dependent Translocation And Fetal Accumulation Of Gold Nanoparticles From Maternal Blood In The Rat., Manuela Semmler-Behnke, Jens Lipka, Alexander Wenk, Martin Schäffler, Furong Tian, Günter Schmid, Günter Oberdörster, Wolfgang G. Kreyling Sep 2014

Size Dependent Translocation And Fetal Accumulation Of Gold Nanoparticles From Maternal Blood In The Rat., Manuela Semmler-Behnke, Jens Lipka, Alexander Wenk, Martin Schäffler, Furong Tian, Günter Schmid, Günter Oberdörster, Wolfgang G. Kreyling

Articles

Background

There is evidence that nanoparticles (NP) cross epithelial and endothelial body barriers. We hypothesized that gold (Au) NP, once in the blood circulation of pregnant rats, will cross the placental barrier during pregnancy size-dependently and accumulate in the fetal organism by 1. transcellular transport across the hemochorial placenta, 2. transcellular transport across amniotic membranes 3. transport through ~20 nm wide transtrophoblastic channels in a size dependent manner. The three AuNP sizes used to test this hypothesis are either well below, or of similar size or well above the diameters of the transtrophoblastic channels.

Methods

We intravenously injected monodisperse, negatively …


Tribes And Race: The Court’S Missed Opportunity In Adoptive Couple V. Baby Girl, Christopher Deluzio Sep 2014

Tribes And Race: The Court’S Missed Opportunity In Adoptive Couple V. Baby Girl, Christopher Deluzio

Pace Law Review

Part I of this article will provide an overview of the legal doctrines implicated in Adoptive Couple v. Baby Girl. First, Part I will discuss both Indian Child Welfare Act’s text and purpose and scholarly attention given to the law. Second, Part I will examine the law of putative fathers insofar as relevant to understanding ICWA’s application in Adoptive Couple. Part II provides insight into the Court’s equal protection jurisprudence with a particular emphasis on considerations of race in adoption and laws implicating Indian tribes. This Part introduces the limited scholarly treatment afforded to the equal protection issues implicated by …


2014 Scas Annual Meeting Program Sep 2014

2014 Scas Annual Meeting Program

Journal of the South Carolina Academy of Science

No abstract provided.


Genotypic And Phenotypic Characterization Of Aerosolized Bacteria Collected From African Dust Events, Christina A. Wilson, Robin L. Brigmon, Chris Yeager, Garriet W. Smith, Shawn W. Polson Sep 2014

Genotypic And Phenotypic Characterization Of Aerosolized Bacteria Collected From African Dust Events, Christina A. Wilson, Robin L. Brigmon, Chris Yeager, Garriet W. Smith, Shawn W. Polson

Journal of the South Carolina Academy of Science

Twenty-one bacteria were isolated and characterized from air samples collected in Africa and the Caribbean by the United States Geological Survey (USGS). Isolates were selected based on preliminary characterization as possible pathogens. Identification of the bacterial isolates was achieved using 16S rRNA gene sequence analysis, fatty acid methyl esters (FAMEs) profiling, the BIOLOG Microlog® System (carbon substrate assay), and repetitive extragenic palindromic (REP)-PCR analysis. The majority of isolates (18/21) were identified as species of the genus Bacillus. Three isolates were classified within the Bacillus cereus senso lato group, which includes Bacillus anthracis, Bacillus thuringiensis, and Bacillus …


Remembering To Perform Actions In The Future: Can Intentions Pop Into Mind?, Gilles O. Einstein Sep 2014

Remembering To Perform Actions In The Future: Can Intentions Pop Into Mind?, Gilles O. Einstein

Journal of the South Carolina Academy of Science

No abstract provided.


Role Of Vitamin A In Retinal Diseases, Rosalie K. Crouch, Masahiro Kono, Peter H. Tang Sep 2014

Role Of Vitamin A In Retinal Diseases, Rosalie K. Crouch, Masahiro Kono, Peter H. Tang

Journal of the South Carolina Academy of Science

Vitamin A has an essential role in vision in that it forms the photosensitive pigments that absorb light and initiate the visual process. However, vitamin A and its analogues also have critical roles in maintaining the structural integrity of the retina. Disruption of the metabolism of vitamin A results in several blinding diseases. This review focuses on our recent studies on the role of a protein critical to the processing of vitamin A, RPE65. The absence or dysfunction of this protein causes the childhood blinding disease Leber congenital amaurosis.


Scas Officers And Council Members 2014-2015 Sep 2014

Scas Officers And Council Members 2014-2015

Journal of the South Carolina Academy of Science

No abstract provided.


Table Of Contents Sep 2014

Table Of Contents

Journal of the South Carolina Academy of Science

No abstract provided.


Developmental Trajectories Of Physical Aggression And Nonaggressive Rule-Breaking Among At-Risk Males And Females During Late Childhood And Early Adolescence, Eugena Givens Sep 2014

Developmental Trajectories Of Physical Aggression And Nonaggressive Rule-Breaking Among At-Risk Males And Females During Late Childhood And Early Adolescence, Eugena Givens

USF Tampa Graduate Theses and Dissertations

Criminological, psychological, and developmental researchers have relentlessly explored behavioral characteristics and juvenile justice outcomes in an effort to establish the most appropriate means of analyzing childhood and adolescent problem behaviors. Cross-discipline, empirical evidence and factor analytic research has consistently identified the presence of two predictive concepts, physical aggression and nonaggressive rule-breaking. Research pertaining to the risk factors and correlates of these two distinct substructures of offending align with theoretically postulated typologies of delinquency and offending as well as the frequently cited patterns of delinquency and offending within reviews of longitudinal research. Using longitudinal data from a sample of 756 at-risk, …


A Globally Sustainable Right To Land: Utilizing Real Property To Protect The Traditional Knowledge Of Indigenous Peoples And Local Communities, Jennifer Lynn Zweig Sep 2014

A Globally Sustainable Right To Land: Utilizing Real Property To Protect The Traditional Knowledge Of Indigenous Peoples And Local Communities, Jennifer Lynn Zweig

Georgia Journal of International & Comparative Law

No abstract provided.


Who's Virus Is It Anyway? How The World Health Organization Can Protect Against Claims Of "Viral Sovereignty", Jason Carter Sep 2014

Who's Virus Is It Anyway? How The World Health Organization Can Protect Against Claims Of "Viral Sovereignty", Jason Carter

Georgia Journal of International & Comparative Law

No abstract provided.


The Intersection Of International Human Rights And Domestic Environmental Regulation, Rebecca M. Bratspies Sep 2014

The Intersection Of International Human Rights And Domestic Environmental Regulation, Rebecca M. Bratspies

Georgia Journal of International & Comparative Law

No abstract provided.


Procedural Rights As A Crucial Tool To Combat Climate Change, Svitlana Kravchenko Sep 2014

Procedural Rights As A Crucial Tool To Combat Climate Change, Svitlana Kravchenko

Georgia Journal of International & Comparative Law

No abstract provided.


Ho-1 Upregulation Attenuates Adipocyte Dysfunction, Obesity, And Isoprostane Levels In Mice Fed High Fructose Diets, Zeid Khitan, Mohit Harsh, Komal Sodhi, Joseph I. Shapiro Md, Nader G. Abraham Sep 2014

Ho-1 Upregulation Attenuates Adipocyte Dysfunction, Obesity, And Isoprostane Levels In Mice Fed High Fructose Diets, Zeid Khitan, Mohit Harsh, Komal Sodhi, Joseph I. Shapiro Md, Nader G. Abraham

Pharmaceutical Science and Research

Background. Fructose metabolism is an unregulated metabolic pathway and excessive fructose consumption is known to activate ROS.HO-1 is a potent antioxidant gene that plays a key role in decreasing ROS and isoprostanes.We examinedwhether the fructosemediated increase in adipocyte dysfunction involves an increase in isoprostanes and that pharmacological induction ofHO-1would decrease both isoprostane levels and adipogenesis. Methods and Results. We examined the effect of fructose, on adipogenesis in human MSCs in the presence and absence of CoPP, an inducer of HO-1. Fructose increased adipogenesis and the number of large lipid droplets while decreasing the number of small lipid droplets (𝑃 < 0.05). Levels of heme and isoprostane in fructose treated MSC-derived adipocytes were increased. CoPP reversed these effects andmarkedly increasedHO-1 and theWnt signaling pathway. Thehigh fructose diet increased heme levels in adipose tissue and increased circulating isoprostane levels (𝑃 < 0.05 versus control). Fructose diets decreasedHO-1 and adiponectin levels in adipose tissue. Induction ofHO-1 by CoPP decreased isoprostane synthesis (𝑃 < 0.05 versus fructose). Conclusion. Fructose treatment resulted in increased isoprostane production and adipocyte dysfunction, which was reversed by the increased expression of HO-1.


External/Internal Optical Adapter With Reverse Biased Photodiodes For Ftir Spectrophotometry, Zhi Xu Sep 2014

External/Internal Optical Adapter With Reverse Biased Photodiodes For Ftir Spectrophotometry, Zhi Xu

UMSL Patents

A Fourier Transfer Infrared (FTIR) spectrophotometer having reduced baseline noise. The system and method include internal or external optical adapters having a moveable beamsplitter for splitting the source light beam into a reference beam and a sample beam, and may include a variable bandpass filter, variable preamplifier and reversed biased photodiodes.

For the most up-to-date information about these patents, including the availability of Certificates of Correction, be sure to check the United States Patent and Trademark Office's free, publicly accessible database: Patent Public Search https://ppubs.uspto.gov/pubwebapp/static/pages/landing.html


Prospectus, September 3, 2014, Peter Cowley, Scott Barnes, Austin Jacobson Sep 2014

Prospectus, September 3, 2014, Peter Cowley, Scott Barnes, Austin Jacobson

Prospectus 2014

SMOKING TO BE BANNED ON PARKLAND CAMPUS, Study Yields Full Genetic Snapshot of Ebola Virus, Diverse Local Agriculture Provides Career Options for Students, Annual Sweetcorn Festival Returns to Urbana, Pediatricians Recommended More Sleep and Later School Start Times for Teens, Back-to-School Tips for All, Reviews of New Pop Music Releases


Ua12/2/1 College Heights Herald, Vol. 90, No. 5, Wku Student Affairs Sep 2014

Ua12/2/1 College Heights Herald, Vol. 90, No. 5, Wku Student Affairs

WKU Administration Documents

WKU campus newspaper reporting campus, athletic and Bowling Green, Kentucky news.

  • Brown, Leah. Campus Offices Move Around – Downing University Center, Augenstein Alumni Center, Craig Alumni Center
  • Eldridge, Brittany. Academic Advising & Retention Center Focuses on Retention
  • Kirk, Kierstin. Learning the Ropes – WKU Challenge Course
  • Voorhees, Jessica. iWKU Adds Updates
  • Voorhees, Jessica. Tennis Courts at South Campus Finished
  • Brown, Leah. WKU & UPIKE Partner to Improve Healthcare – University of Pikeville
  • Little, Emily. Editorial Cartoon Big Red at a Restroom
  • Don’t Let WKU Forget About Transgender Students
  • Hardin, Erika. Be a Healthy Hilltopper Despite the Meal Plan – Dining …


Grad Student Discovers New Species Of Titanosaurian Dinosaur, Ohio University College Of Arts & Sciences Sep 2014

Grad Student Discovers New Species Of Titanosaurian Dinosaur, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.


Evidence For Transfer Of Membranes From Mesenchymal Stem Cells To Hl-1 Cardiac Cells, Robert A. Boomsa, David L. Geenen Sep 2014

Evidence For Transfer Of Membranes From Mesenchymal Stem Cells To Hl-1 Cardiac Cells, Robert A. Boomsa, David L. Geenen

Peer Reviewed Articles

This study examined the interaction of mouse bone marrow mesenchymal stem cells (MSC) with cardiac HL-1 cells during coculture by fluorescent dye labeling and then flow cytometry. MSC were layered onto confluent HL-1 cell cultures in a 1 : 4 ratio. MSC gained gap junction permeant calcein from HL-1 cells after 4 hours which was partially reduced by oleamide. After 20 hours, 99% MSC gained calcein, unaffected by oleamide. Double-labeling HL-1 cells with calcein and the membrane dye DiO resulted in transfer of both calcein and DiO to MSC. When HL-1 cells were labeled with calcein and MSC with DiO, …


The Tiger Vol. 108 Issue 20 2014-09-09, Clemson University Sep 2014

The Tiger Vol. 108 Issue 20 2014-09-09, Clemson University

Tiger Newspapers

No abstract provided.


Volunteers Needed To Plant Chestnut Trees At Wayne National Forest, Oct. 25, Ohio University College Of Arts & Sciences Sep 2014

Volunteers Needed To Plant Chestnut Trees At Wayne National Forest, Oct. 25, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.


Depressive-Like Behavioral Response Of Adult Male Rhesus Monkeys During Routine Animal Husbandry Procedure, Michael B. Hennessy, Brenda Mccowan, Jing Jiang, John P. Capitanio Sep 2014

Depressive-Like Behavioral Response Of Adult Male Rhesus Monkeys During Routine Animal Husbandry Procedure, Michael B. Hennessy, Brenda Mccowan, Jing Jiang, John P. Capitanio

Psychology Faculty Publications

Social isolation is a major risk factor for the development of depressive illness; yet, no practical nonhuman primate model is available for studying processes involved in this effect. In a first study, we noted that adult male rhesus monkeys housed individually indoors occasionally exhibited a hunched, depressive-like posture. Therefore, Study 2 investigated the occurrence of a hunched posture by adult males brought from outdoor social groups to indoor individual housing. We also scored two other behaviors—lying on the substrate and day time sleeping—that convey an impression of depression. During the first week of observation following individual housing, 18 of 26 …


Bioinformatics Journal Club: Explosion Of Bioinformatics Careers, Sept. 9, Ohio University College Of Arts & Sciences Sep 2014

Bioinformatics Journal Club: Explosion Of Bioinformatics Careers, Sept. 9, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.


High Mrsa Carriage Rate Among Nursing Microbiology Students, Alan Lee Gillen, Whitney O. Daycock, Andrew Serafin Sep 2014

High Mrsa Carriage Rate Among Nursing Microbiology Students, Alan Lee Gillen, Whitney O. Daycock, Andrew Serafin

Faculty Publications and Presentations

Staphylococcus aureus is a common cause of disease, particularly in colonized persons. Although methicillin-resistant S. aureus (MRSA) infections have become increasingly reported, populationbased studies of students preparing for the health professions having S. aureus and MRSA colonization are lacking. We have found that students in microbiology classes having more contact with individuals in a healthcare setting are more likely to carry MRSA in their nares and axilla. The classes who had the highest rate of MRSA carriage during the school year, 2013-2014, were those with nursing students, who had a greater exposure to clinical settings and nursing homes. The class …


Unbiased Analysis Of Pancreatic Cancer Radiation Resistance Reveals Cholesterol Biosynthesis As A Novel Target For Radiosensitisation., Joshua J. Souchek, Michael J. Baine, Chi Lin, Satyanarayana Rachagani, Suprit Gupta, Sukhwinder Kaur, K Lester, D Zheng, S Chen, Lynette Smith, A Lazenby, Sonny L. Johansson, Maneesh Jain, Surinder K. Batra Sep 2014

Unbiased Analysis Of Pancreatic Cancer Radiation Resistance Reveals Cholesterol Biosynthesis As A Novel Target For Radiosensitisation., Joshua J. Souchek, Michael J. Baine, Chi Lin, Satyanarayana Rachagani, Suprit Gupta, Sukhwinder Kaur, K Lester, D Zheng, S Chen, Lynette Smith, A Lazenby, Sonny L. Johansson, Maneesh Jain, Surinder K. Batra

Journal Articles: Biochemistry & Molecular Biology

BACKGROUND: Despite its promise as a highly useful therapy for pancreatic cancer (PC), the addition of external beam radiation therapy to PC treatment has shown varying success in clinical trials. Understanding PC radioresistance and discovery of methods to sensitise PC to radiation will increase patient survival and improve quality of life. In this study, we identified PC radioresistance-associated pathways using global, unbiased techniques.

METHODS: Radioresistant cells were generated by sequential irradiation and recovery, and global genome cDNA microarray analysis was performed to identify differentially expressed genes in radiosensitive and radioresistant cells. Ingenuity pathway analysis was performed to discover cellular pathways …


September 9, 2014 Finance & Facilities (F&F) Committee Meeting, Evp For Administration Sep 2014

September 9, 2014 Finance & Facilities (F&F) Committee Meeting, Evp For Administration

Finance and Facilities Committee

Documents related to the September 9, 2014 Board of Regents' Finance and Facilities Committee Meeting. (Agenda, Minutes, eBook, Notice)


The Current Volume 25 : Issue 3, Nova Southeastern University Sep 2014

The Current Volume 25 : Issue 3, Nova Southeastern University

Student Newspapers

No abstract provided.


Daily Eastern News: September 09, 2014, Eastern Illinois University Sep 2014

Daily Eastern News: September 09, 2014, Eastern Illinois University

September

No abstract provided.


September 9, 2014, The Daily Mississippian Sep 2014

September 9, 2014, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.


A Rational Framework For Evaluating The Next Generation Of Vaccines Against Mycobacterium Avium Subspecies Paratuberculosis, John P. Bannantine, Murray E. Hines Ii, Luiz E. Bermudez, Adel M. Talaat, Srinand Sreevatsan, Judith R. Stabel, Yung-Fu Chang, Paul M. Coussens, Raúl G. Barletta, William C. Davis, Desmond M. Collins, Yrjö T. Gröhn, Vivek Kapur Sep 2014

A Rational Framework For Evaluating The Next Generation Of Vaccines Against Mycobacterium Avium Subspecies Paratuberculosis, John P. Bannantine, Murray E. Hines Ii, Luiz E. Bermudez, Adel M. Talaat, Srinand Sreevatsan, Judith R. Stabel, Yung-Fu Chang, Paul M. Coussens, Raúl G. Barletta, William C. Davis, Desmond M. Collins, Yrjö T. Gröhn, Vivek Kapur

School of Veterinary and Biomedical Sciences: Faculty Publications

Since the early 1980s, several investigations have focused on developing a vaccine against Mycobacterium avium subspecies paratuberculosis (MAP), the causative agent of Johne's disease in cattle and sheep. These studies used whole-cell inactived vaccines that have proven useful in limiting disease progression, but have not prevented infection. In contrast, modified live vaccines that invoke a Th1 type immune response, may improve protection against infection. Spurred by recent advances in the ability to create defined knockouts in MAP, several independent laboratories have developed modified live vaccine candidates by transcriptional mutation of virulence and metablolic genes in MAP. In order to accelerate …