Digital Commons Network^™

Determination Of Disulfide Bond Connecting Patterns Via Tandem Mass Spectrometry (Msn) And Biomolecular Ion/Radical Reactions, Kirt Lenroy Durand

Open Access Dissertations

Disulfide bond formation is one of the most common post translational modifications to occur in proteins and naturally occurring peptides. Disulfide bond formation plays a critical role in stabilizing their three-dimensional structure; therefore, it is very important to pinpoint the correct disulfide bond connecting pattern in order to fully understand the biological functions of these proteins and peptides. To fully characterize an analyte containing disulfide bonds, the sequence must first be known followed by the disulfide bond connecting pattern. This presents an analytical challenge as there are very few methodologies that can produce those essential pieces of information. The gold …

Assessment Of The Adoption Of Agroforestry Technologies By Limited-Resource Farmers In North Carolina, Paula E. Faulkner, Bismark Owooh, Joshua Idassi

Faculty Publications

Agroforestry is a natural resource management system that integrates trees, forages, and livestock. The study reported here was conducted to determine farmers' knowledge about and willingness to adopt agroforestry technologies in North Carolina. The study reported participants were primarily older, male farmers, suggesting the need to attract more females and younger individuals to adopt agroforestry technologies. The increasing number of diversified farm operators presents a new audience for Extension educators to offer programs to improve limited-resource farmers' livelihood. The study recommends Extension training programs and information centers for farmers who need skills and knowledge to manage agroforestry technologies.

Geogram 2014, David J. Keeling Editor, Wku Department Of Geography And Geology

Earth, Environmental, and Atmospheric Sciences Publications

No abstract provided.

Fall 2014, Friends Of Dacus Library

Friends of Dacus Library Newsletter

Inside this Issue:

Archives Kickoff for Winthrop’s Integration Commemoration
Giving Thanks … Dean Herring
Woodfork Scholarship
Active Friends Member List for 2015
Rudy Mancke to Speak
Note From the Chair … Dr. Jane White
Membership Form

Integrated Transcriptome Analysis Reveals Mirna-Mrna Crosstalk In Laryngeal Squamous Cell Carcinoma., Yang Zhang, Yong Chen, Jinhai Yu, Guiming Liu, Zhigang Huang

College of Science & Mathematics Departmental Research

Next generation sequencing (NGS) has proven to be a powerful tool in delineating myriads of molecular subtypes of cancer, as well as in revealing accumulation of genomic mutations throughout cancer progression. Whole genome microRNA (miRNA) and mRNA expression profiles were obtained from patients with laryngeal squamous cell carcinoma (LSCC) using deep sequencing technology, and were analyzed by utilizing integrative computational approaches. A large number of protein-coding and non-coding genes were detected to be differentially expressed, indicating a functional switch in LSCC cells. A total of 127 mutated genes were detected to be significantly associated with ectoderm and epidermis development. Eleven …

Acclimation Of Photosynthetic Temperature Optima Of Temperate And Boreal Tree Species In Response To Experimental Forest Warming, Kerrie M. Sendall, Peter B. Reich, Changming Zhao, Hou Jihua, Xia Orong Wei, Artur Stefanski, Karen Rice, Roy L. Rich, Rebecca A. Montgomery

Faculty Research & Creative Activity

Rising temperatures caused by climate change could negatively alter plant ecosystems if temperatures exceed optimal

temperatures for carbon gain. Such changes may threaten temperature-sensitive species, causing local extinctions and

range migrations. This study examined the optimal temperature of net photosynthesis (Topt) of two boreal and four

temperate deciduous tree species grown in the field in northern Minnesota, United States under two contrasting temperature

regimes. We hypothesized that Topt would be higher in temperate than co-occurring boreal species, with

temperate species exhibiting greater plasticity in Topt, resulting in better acclimation to elevated temperatures. The

chamberless experiment, located at two sites in …

Bioeconomic Factors Of Beef Heifer Maturity To Consider When Establishing Criteria To Optimally Select And/Or Retain Herd Replacements, M. C. Stockton, R. K. Wilson, Dillon M. Feuz, L. A. Stalker, R. N. Funston

Applied Economics Faculty Publications

Understanding the biology of heifer maturity and its relationship to calving difficulty and subsequent breeding success is a vital step in building abioeconomic model to identify optimal production and profitability. A limited dependent variable probit model is used to quantify the responses among heifer maturities, measured by a maturity index (MI), on dystocia and second pregnancy. The MI account for heifer age, birth BW, prebreeding BW, nutrition level, and dam size and age and is found to be inversely related to dystocia occurrence. On average there is a 2.2% increase in the probability of dystocia with every 1 point drop …

Profile: Our Place In The World, University Relations

Profile (1996-)

This issue of Profile speaks to the ways in which campus members are interacting with the world and illuminates our active participation in the 21st-century global community. It includes a story on the ways in which Morris students, faculty, and staff have reached out to and benefited from their interactions with the local and growing Latino community. It also features recent recipients of the David C. Johnson Award for International Service Learning.

--From Chancellor Johnson's Message

October 2014, Issue 4, James Madison University Uhc Marketing Team

Potty Mouth

No abstract provided.

October 1, 2014 Cal Poly Report, Public Affairs Office

Cal Poly Report

No abstract provided.

Data-Driven Diagnostics Of Terrestrial Carbon Dynamics Over North America, Jingfeng Xiao, Scott V. Ollinger, Steve Frolking, George C. Hurtt, David Y. Hollinger, Kenneth J. Davis, Yude Pan, Xiaoyang Zhang, Feng Deng, Jiquan Chen, Dennis D. Baldocchi, Bevery E. Law, M. Altaf Arain, Ankur R. Desai, Andrew D. Richardson, Ge Sun, Brian Amiro, Hank Margolis, Lianhong Gu, Russell L. Scott, Peter D. Blanken, Andrew E. Suyker

GSCE Faculty Publications

The exchange of carbon dioxide is a key measure of ecosystem metabolism and a critical intersection between the terrestrial biosphere and the Earth's climate. Despite the general agreement that the terrestrial ecosystems in North America provide a sizeable carbon sink, the size and distribution of the sink remain uncertain. We use a data-driven approach to upscale eddy covariance flux observations from towers to the continental scale by integrating flux observations, meteorology, stand age, aboveground biomass, and a proxy for canopy nitrogen concentrations from AmeriFlux and Fluxnet-Canada Research Network as well as a variety of satellite data streams from the MODIS …

Illuminated Magazine, School Of Graduate Studies, East Tennessee State University

Illuminated: Graduate Student Research Magazine

Where Are They Now? [Geoff Adebonojo & Marla Perna]; Evidence from the Earth: Researching Cranial Material of Mio-Pliocene Salamanders at the Gray Fossil Site [Geosciences, M.S. (Paleontology) Graduate Student: Hannah Darcy]; Healthy Plant-Based Fats: An Ongoing Exploration of Triacylglycerol Oil Accumulation in Plants [Biology, M.S. (Biology) Graduate Student: Parker Dabbs]; ETSU Housing and Residence Life [Dr. Bonnie Burchett]; The Creative Process: Paintings Inspired by History and Connectivity [Art, M.F.A. (Studio Art) Graduate Student: Katherine Block]; Maternal and Child Health: Informing and Encouraging Healthy Families [Public Health, Dr.P.H. (Epidemiology) Graduate Student: Marc Stevens, Jr.]

Low O2-Induced Atp Release From Erythrocytes Of Humans With Type 2 Diabetes Is Restored By Physiological Ratios Of C-Peptide And Insulin, Jennifer P. Richards, Gina L.C. Yosten, Grant R. Kolar, Cory W. Jones, Alan H. Stephenson, Mary L. Ellsworth, Randy S. Sprague

Biological Sciences Faculty Research & Creative Works

ATP release from erythrocytes in response to reduced oxygen (O2) tension stimulates local vasodilation, enabling these cells to direct perfusion to areas in skeletal muscle in need of O2. Erythrocytes of humans with type 2 diabetes do not release ATP in response to low O2. Both C-peptide and insulin individually inhibit low O2-induced ATP release from healthy human erythrocytes, yet when co administered at physiological concentrations and ratios, no inhibition is seen. Here, we determined: that 1) eryth-rocytes of healthy humans and humans with type 2 diabetes possess a C-peptide receptor (GPR146), 2) the combination of C-peptide and insulin at …

Inequitable Conduct And Supplemental Examination: Promise, Procedure, And Particulars, Amanda K. Murphy, Jonathan R. K. Stroud

Buffalo Intellectual Property Law Journal

The America Invents Act, signed into law on September 16, 2011, ushered in an array of patent reforms. One overlooked procedure, Supplemental Examination, seeks to purge putative instances of inequitable conduct prior to litigation by allowing patent owners to submit prior art and short statements to the USPTO after patent issuance. Few parties have used it. We analyze the law of inequitable conduct, explain the Supplemental Examination procedure, and discuss potential reasons for its lack of popularity among patent owners.

Jeanne Clery Disclosure Of Campus Security Policy And Campus Crime Statistics Report, 2013, University Of Arkansas, Fayetteville. Police Department

Jeanne Clery Disclosure of Campus Security Policy

No abstract provided.

16 Masters And 4 Bachelor's Students Complete Geology Theses, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Identity Crisis: Making Sense Of Post-Apartheid Relationships Between Whiteness And Antiracism, Justin Bradshaw

Independent Study Project (ISP) Collection

This independent study project sought to explore white South African antiracist identities during post-apartheid South Africa and how the ways of making meaning of an antiracist identity contribute to and reflect the conceptual frameworks that already exist. Furthermore, this study intended to illuminate how white identifying antiracist persons in post-apartheid South Africa can be allies in the struggle for a more racially equitable society. The frameworks involved in this project are the academic study of whiteness, critical race theory, and antiracism.

In this study the researcher interviewed four white South Africans who, in one way or another, are intellectually involved …

Downregulation Of Cox-2 And Cyp 4a Signaling By Isoliquiritigenin Inhibits Human Breast Cancer Metastasis Through Preventing Anoikis Resistance, Migration And Invasion, Hao Zheng, Ying Li, Yuzhong Wang, Haixia Zhao, Jing Zhang, Hongyan Chai, Tian Tang, Jiang Yue, Austin M. Guo, Jing Yang

NYMC Faculty Publications

Flavonoids exert extensive in vitro anti-invasive and in vivo anti-metastatic activities. Anoikis resistance occurs at multiple key stages of the metastatic cascade. Here, we demonstrate that isoliquiritigenin (ISL), a flavonoid from Glycyrrhiza glabra, inhibits human breast cancer metastasis by preventing anoikis resistance, migration and invasion through downregulating cyclooxygenase (COX)-2 and cytochrome P450 (CYP) 4A signaling. ISL induced anoikis in MDA-MB-231 and BT-549 human breast cancer cells as evidenced by flow cytometry and the detection of caspase cleavage. Moreover, ISL inhibited the mRNA expression of phospholipase A2, COX-2 and CYP 4A and decreased the secretion of prostaglandin E2 (PGE2) and 20-hydroxyeicosatetraenoic …

The Language Of Mens Rea, Matthew R. Ginther, Francis X. Shen, Richard J. Bonnie, Morris B. Hoffman, Owen D. Jones, Rene Marois, Kenneth W. Simons

Vanderbilt Law Review

To be guilty of a crime, generally one must commit a bad act while in a culpable state of mind. But the language used to define, partition, and communicate the variety of culpable mental states (in Latin, mens rea) is crucially important. For depending on the mental state that juries attribute to him, a defendant can be convicted-for the very same act and the very same consequence-of different crimes, each with different sentences.

The influential Model Penal Code ("MPC") of 1962 divided culpable mental states into four now-familiar kinds: purposeful, knowing, reckless, and negligent.' Both before the MPC and since, …

Faculty Notes - John Carroll University, John Carroll University

Faculty Notes - John Carroll University

October 2014, Volume 7, Issue 3

The Clinical Psychology Training Program At The University Of Nebraska–Lincoln, David J. Hansen, Timothy D. Nelson, David Dilillo, Debra A. Hope

Department of Psychology: Faculty Publications

The Clinical Psychology Training Program (CPTP) at the University of Nebraska–Lincoln (UNL) has been continuously accredited by the American Psychological Association (APA) since 1948, the first year any programs were accredited. The CPTP’s history and approach to training through the years have been described in numerous articles (DiLillo & McChargue, 2007; Hargrove, 1991; Hargrove & Howe, 1981; Hargrove & Spaulding, 1988; Hope, Hansen, & Cole, 1994; Howe, 1974; Howe & Neimeyer, 1979; Jones & Levine, 1963; Rivers & Cole, 1976). Our program was historically described as a “Community-Clinical” psychology training program, and this focus on understanding and enhancing well-being at …

Examination Of Tinnitus: Study Of Synapses On Fusiform Cells In The Dorsal Cochlear Nucleus, Stephanie Bouanak

Senior Honors Projects

The dorsal cochlear nucleus (DCN) is a multimodal processing station found at the junction of the auditory nerve and brainstem medulla. Tinnitus-induced neuronal hyperactivity has been observed in the DCN and, thus, suggested to be the lowest region of the auditory nerve with such hyperactivity. The main integrative units of the DCN are the fusiform cells, receiving and processing inputs from auditory sources before transmitting information to higher auditory pathways. Neural hyperactivity is induced in fusiform cells of the DCN following intense sound exposure. Researchers suggest that fusiform cells may be implicated as major generators of noise-induced tinnitus. Despite previous …

Habitat Associations And Predictive Distribution Models Of Commercially Important Rockfish Species Along California's Central Coast, Heather Marie Bolton

SNS Master's Theses

While commercially important, the red rockfish complex, Vermilion Rockfish (Sebastes miniatus), Canary Rockfish (Sebastes pinniger) and Yelloweye Rockfish (Sebastes ruberrimus), is emblematic of our limited knowledge of the distribution and habitat associations of ecologically and economically important fishes along California’s central coast. We used videographic and photographic imagery from a remotely operated vehicle (ROV), coupled with high resolution multibeam derived maps of the seafloor to determine a) the fine scale habitat associations of red rockfishes along California’s central coast, and b) the potential distribution of small Canary Rockfish (10-40 centimeters TL) beyond surveyed areas using predictive species-specific distribution models. Across …

Assessment Of Irrigation Use On Crop Yield And Water Supplies In The Midwestern U.S., Wei-Chih Chen

Open Access Dissertations

Climate plays an important role in many aspects of hydrological and agricultural systems. Temperature and precipitation are usually the main forcing inputs for hydrological and agricultural simulations, while wind effect has generally been neglected in previous research. Wind speed is, however, an important factor for many physical processes, including evaporation from soil, and transpiration from plants. In order to investigate how climate variability impacts agricultural production, there are three hypotheses addressed in this dissertation. Hypothesis 1 is that the representation of changing wind speed will play an important role in the simulation of hydrological processes, and that the effect of …

Algorithm-Circuit Co-Design For Detecting Symptomatic Patterns In Biological Signals, Himanshu Markandeya

Open Access Dissertations

The advancement in scaled Silicon technology has accelerated the development of a wide range of applications in various fields including medical technology. It has immensely contributed to finding solutions for monitoring general health as well as alleviating intractable disorders in the form of implantable and wearable systems. This necessitates the development of energy efficient and functionally efficacious systems. This thesis has explored the algorithm-circuit co-design approach for developing an energy efficient epileptic seizure detection processor which could be used for implantable epilepsy prosthesis. Novel wavelet transform based algorithms are proposed for accurate detection of epileptic seizures. Energy efficient techniques at …

Friends Of Musselman Library Newsletter Fall 2014, Musselman Library

Friends of Musselman Library Newsletter

Table of Contents: From the Director: Gettysburgreat: The Campaign for Our College (Robin Wagner); Popular Middle East Series Continues; Letter from Edgar Rice Burroughs Explains Origin of Tarzan's Name; Library Celebration Owl & Nightingale's 100th Anniversary (Chelsea Bucklin '10, Chris Kauffman '92, Elyse Bennett '10); Encore! Owl & Nightingale Players Take Center Stage at Homecoming (Paul Di Salvo '13, Chelsea Bucklin '10, Aliena J. (Fischer) Garnard '93, Kelsey Lamagdeleine '09, Sean Valentine '05); Research Reflections: Shakespeare Folio (Chris Kauffman '92); GettDigital- The Story Continues: Professor Visits Italy and Recreates WWII Photos (Alan Perry, Catherine Perry); Don't Be Antisocial; Obama Awards …

Gettysburg: Our College's Magazine Fall 2014, Communications & Marketing

Gettysburg: Our College’s Magazine

Table of Contents:

From the President Janet Morgan Riggs '77

A Running Leap of Faith (Cindy Holck McWilliams '84)

Office Hours: Prof. Timothy N. Good P'14

His Country is Tibet (Lhagyari Trichen Namgyal Wangchuk '17) Kasey Varner '14

The 411: Bob Joseph '69

What Makes A Great... Faculty Thomas F. George '67

Chief Diversity Officer Appointed (Jeanne Arnold)

Tony Awards Spotlight Charlotte Wilcox '69

The Garden State's CEO of Fun (Wayne Hasenbalg '76)

Stadium Locker Room Revamped

Can You See Yourself in Gettysburg's Future? Matt Haag '94

Making Gettysburg and Great Inseparable

$4,000 Made All The Difference (Sarah Robertson '17) …

Yale Medicine : Alumni Bulletin Of The School Of Medicine, Autumn 2014, Yale University. School Of Medicine

Yale Medicine Magazine - alumni bulletin and magazine

This is the Autumn 2014 issue of Yale Medicine: alumni bulletin of the School of Medicine, v. 48, no. 3. Prepared in cooperation with the alumni and development offices at the School of Medicine. Earlier volumes are called Yale School of Medicine alumni bulletins, dating from v.1 (1953) through v.13 (1965).

Connections Between Student Explanations And Arguments From Evidence About Plant Growth, Jenny Dauer, Jennifer H. Doherty, Allison L. Freed, Charles W. Anderson

School of Natural Resources: Faculty Publications

We investigate how students connect explanations and arguments from evidence about plant growth and metabolism—two key practices described by the Next Generation Science Standards. This study reports analyses of interviews with 22 middle and high school students postinstruction, focusing on how their sense-making strategies led them to interpret—or misinterpret—scientific explanations and arguments from evidence. The principles of conservation of matter and energy can provide a framework for making sense of phenomena, but our results show that some students reasoned about plant growth as an action enabled by water, air, sunlight, and soil rather than a process of matter and energy …

Airborne Characterization Of Smoke Marker Ratios From Prescribed Burning, A. P. Sullivan, A. A. May, T. Lee, G. R. Mcmeeking, S. M. Kreidenweis, S. K. Akagi, Robert Yokelson, S. P. Urbanski, J. L. Collett Jr.

Chemistry and Biochemistry Faculty Publications

A Particle-Into-Liquid Sampler – Total Organic Carbon (PILS-TOC) and fraction collector system was flown aboard a Twin Otter aircraft sampling prescribed burning emissions in South Carolina in November 2011 to obtain smoke marker measurements. The fraction collector provided 2 min time-integrated offline samples for carbohydrate (i.e., smoke markers levoglucosan, mannosan, and galactosan) analysis by high-performance anion-exchange chromatography with pulsed amperometric detection. Each fire location appeared to have a unique 1levoglucosan /1water-soluble organic carbon (WSOC) ratio (RF01/RF02/RF03/RF05 = 0.163± 0.007 μg C μg−1 C, RF08 = 0.115 ± 0.011 μg C μg−1 C, RF09A = 0.072 ± 0.028 μgC μg−1 C, …