Digital Commons Network^™

Philanthropic Pharmacy: Helping Patients In Need, Krista Brooks, Tiffany Kessler, Randy Curry, Kalie Kerth, Erin Callen, Nina Morris, Virgil Van Dusen, W. Steven Pray, Annie Ellis

Faculty Articles & Research

If asked, what would a pharmacist’s justification be for entering the profession? For many, that answer would be, “I wanted a career where I could help people.” Pharmacy is an excellent way to meet that goal, but it is frustrating at times. One such situation is when patients cannot afford their prescriptions. Even the most altruistic pharmacist cannot stay in business if drugs are given out for free. As a result, patients with no means to pay may leave the pharmacy without their medications, opting to forgo care. Of course, that has the potential to endanger their health if these …

Hdac8 And Stat3 Repress Bmf Gene Activity In Colon Cancer Cells, Y Kang, Hui Nian, P Rajendran, W Dashwood, John T. Pinto, E Ho, R Dashwood

NYMC Faculty Publications

Histone deacetylase (HDAC) inhibitors are undergoing clinical trials as anticancer agents, but some exhibit resistance mechanisms linked to anti-apoptotic Bcl-2 functions, such as BH3-only protein silencing. HDAC inhibitors that reactivate BH3-only family members might offer an improved therapeutic approach. We show here that a novel seleno-α-keto acid triggers global histone acetylation in human colon cancer cells and activates apoptosis in a p21-independent manner. Profiling of multiple survival factors identified a critical role for the BH3-only member Bcl-2-modifying factor (Bmf). On the corresponding BMF gene promoter, loss of HDAC8 was associated with signal transducer and activator of transcription 3 (STAT3)/specificity protein …

Faculty Council Minutes October 16, 2014, Bronx Community College Faculty Council

BCC Governance Archives

Minutes for the meeting of the Faculty Council on October 16, 2014.

Should Inherent Human Dignity Be Considered Intrinsically Heuristic?, Bharat Ranganathan

Religion Faculty Publications

What are “human rights” supposed to protect? According to most human rights doctrines, including most notably the Universal Declaration of Human Rights (UDHR), human rights aim to protect “human dignity.” But what this concept amounts to and what its source is remain unclear. According to Glenn Hughes (2011), human rights theorists ought to consider human dignity as an “intrinsically heuristic concept,” whose content is partially understood but is not fully determined. In this comment, I criticize Hughes's account. On my view, understanding inherent human dignity as an intrinsically heuristic concept tethers it to an “indeterminateness of sense,” which leaves it …

Western News, October 16, 2014, Western Michigan University

Western News (1972-2018)

Story highlights: Dunn sets direction for this academic year; Annual homecoming week starts Oct. 20; Trustees approve name for new residence halls; On Campus with Blaine McFerrin.

Otter Realm, October 16, 2014, California State University, Monterey Bay

The Otter Realm

Requiem for a Contract: CSU Faculty Protest for Smaller Classes and Adequate Raises -- The Intersection of Hope and Freedom -- What You Otter Be Doing October 16 - October 29 -- A Glimpse of What Could Be: National Consortium of Scholars Discuss Social Action Through Humanities, Arts and Design --Feds Pay Homage to Central Coast Veterans: Final Resting Ground Approved -- Putting Up A Clean Front: Monterey's Sit-Lie Ban Hides the Homeless Population -- Bill Bans "Gay/Trans Panic" Defense: Good News for LGBTQQ+ Community -- It's Out-Ober: Here Is What You Need To Know -- Monterey Bay Experiences A …

Ay 14-15 Meeting 2014-10-16, Faculty Senate

Faculty Senate Minutes

No abstract provided.

An Optimal Calibration Procedure For A Telemac-2d Model Of The Eastern Coast Of Ireland, Garrett Keane, Andrew Stokes, Zeinab Bedri, John O'Sullivan

Conference papers

A review of the literature shows that most model calibrations involve the adjustment of the bottom friction coefficient to minimise the error between predicted and measured tidal elevations. In this study, an alternative procedure is adopted when calibrating a Telemac2D model covering an area on the Eastern coast of Ireland. The model is forced with eight principal tidal constituents derived from the MIKE 21 global model. It is calibrated separately for the two principal constituents, M2 and S2. The field data comprises tidal elevations recorded at five locations over a full lunar cycle in October 1998 and Spring and Neap …

October 16, 2014, James Madison University

The Breeze, 2010-2019

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

The Tiger Vol. 108 Issue 31 2014-10-16, Clemson University

Tiger Newspapers

No abstract provided.

Aerosol Emissions From Prescribed Fires In The United States: A Synthesis Of Laboratory And Aircraft Measurements, A. A. May, G. R. Mcmeeking, T. Lee, J. W. Taylor, J. S. Craven, I. R. Burling, A. P. Sullivan, Sheryl Kashi Akagi, J. L. Collett Jr., M. Flynn, H. Coe, S. P. Urbanski, J. H. Seinfeld, Robert Yokelson, S. M. Kreidenweis

Chemistry and Biochemistry Faculty Publications

Aerosol emissions from prescribed fires can affect air quality on regional scales. Accurate representation of these emissions in models requires information regarding the amount and composition of the emitted species.Wemeasured a suite of submicron particulatematter species in young plumes emitted from prescribed fires (chaparral and montane ecosystems in California; coastal plain ecosystem in South Carolina) and from open burning of over 15 individual plant species in the laboratory. We report emission ratios and emission factors for refractory black carbon (rBC) and submicron nonrefractory aerosol and compare field and laboratory measurements to assess the representativeness of our laboratory-measured emissions. Laboratory measurements …

"Nolite Te Bastardes Carborundorum": Reproduction And Resistance In Octavia Butler, Margaret Atwood, And The Alien Series, Amandine Faucheux

Foreign Languages & Literatures ETDs

This thesis proposes a comparative study of Octavia E. Butlers Xenogenesis trilogy (1987-89), Margaret Atwood's The Handmaid's Tale (1985), and the Alien series (1979-97). I argue that these three texts resist patriarchal oppression upon the female fertile body. I examine how they rewrite and subvert such institutions as motherhood, the family, and the heterosexual couple, in order to redefine and empower woman. In the first chapter, I argue that Octavia Butler rewrites Western origin stories in order to put woman and people of color at its center, which provokes a redefinition of the essential woman. In chapter two, I examine …

Seminar: ‘The Biology Behind Modeling Of Vector-Borne Diseases,’ Oct. 16, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

The Utah Statesman, October 16, 2014, Utah State University

The Utah Statesman

Weekly student newspaper of Utah State University in Logan.

Mitochondria Expert Invited To Nih Strategic Workshop, Jeff Hansen

Browse All News

No abstract provided.

The Gazette October 16, 2014, Langston University

LU Gazette, 2010-2019

The student newspaper for Langston University

Daily Eastern News: 10/16/2014, Eastern Illinois University

October

No abstract provided.

The Comment, October 16, 2014, Bridgewater State University

The Comment

No abstract provided.

Pepperbox - October 16, 2014, Student Newspaper Of Arcata High School

The Pepperbox

Volume 87, Number 1

The Pan American (2014-10-16), Susan Gonzalez, Andrew Vera

UTPA Archives - The Pan American Newspaper

Vol. 71, No. 8

Sculpting The Umls Refined Semantic Network, Zhe He, C. Paul Morrey, Yehoshua Perl, Gai Elhanan, Ling Chen, Yan Chen, James Geller

Publications and Research

Background The Refined Semantic Network (RSN) for the UMLS was previously introduced to complement the UMLS Semantic Network (SN). The RSN partitions the UMLS Metathesaurus (META) into disjoint groups of concepts. Each such group is semantically uniform. However, the RSN was initially an order of magnitude larger than the SN, which is undesirable since to be useful, a semantic network should be compact. Most semantic types in the RSN represent combinations of semantic types in the UMLS SN. Such a “combination semantic type” is called Intersection Semantic Type (IST). Many ISTs are assigned to very few concepts. Moreover, when reviewing …

Hawks' Herald -- October 16, 2014, Roger Williams University

Hawk's Herald

No abstract provided.

Curriculum Minutes 10/16/2014, Curriculum Committee

Curriculum Committee Minutes

In these minutes: Discussion of minimum credits required in a major; catalog course change clean-up in the Division of the Humanities, Division of Science and Mathematics, Division of the Social Sciences, and Interdisciplinary Studies

The Missouri Miner, October 16, 2014

The Missouri Miner Newspaper

No abstract provided.

Galapagos Tortoises Topic For Science Cafe, Edwin Smith

University of Mississippi News

UM biology professor will discuss preservation efforts in Oct. 21 presentation

Interrater Reliability Of The Wolf Motor Function Test–Functional Ability Scale: Why It Matters, Susan V. Duff, Jiaxue He, Monica A. Nelsen, Christianne J. Lane, Veronica T. Rowe, Steve L. Wolf, Alexander W. Dromerick, Carolee J. Winstein

Physical Therapy Faculty Articles and Research

Background. One important objective for clinical trialists in rehabilitation is determining efficacy of interventions to enhance motor behavior. In part, limitation in the precision of measurement presents a challenge. The few valid, low-cost observational tools available to assess motor behavior cannot escape the variability inherent in test administration and scoring. This is especially true when there are multiple evaluators and raters, as in the case of multisite randomized controlled trials (RCTs). One way to enhance reliability and reduce variability is to implement rigorous quality control (QC) procedures. Objective. This article describes a systematic QC process used to refine …

Fairchild Dairy Marks 25 Years Of Research, Michelle Morrissey

UNH Today Archive

No abstract provided.

Artesunate Induces Necrotic Cell Death In Schwannoma Cells., R. W. Button, F. Lin, E. Ercolano, J. H. Vincent, B. Hu, C. O. Hanemann, S. Luo

Peninsula Medical School

Established as a potent anti-malaria medicine, artemisinin-based drugs have been suggested to have anti-tumour activity in some cancers. Although the mechanism is poorly understood, it has been suggested that artemisinin induces apoptotic cell death. Here, we show that the artemisinin analogue artesunate (ART) effectively induces cell death in RT4 schwannoma cells and human primary schwannoma cells. Interestingly, our data indicate for first time that the cell death induced by ART is largely dependent on necroptosis. ART appears to inhibit autophagy, which may also contribute to the cell death. Our data in human schwannoma cells show that ART can be combined …

Dengue Virus Neutralizing Antibody Levels Associated With Protection From Infection In Thai Cluster Studies, Darunee Buddhari, Jared Aldstadt, Timothy P. Endy, Anon Srikiatkhachorn, Butsaya Thaisomboonsuk, Chonticha Klungthong, Ananda Nisalak, Benjawan Khuntirat, Richard G. Jarman, Stefan Fernandez, Stephen J. Thomas, Thomas W. Scott, Alan Rothman, In-Kyu Yoon

Institute for Immunology and Informatics Faculty Publications

Background

Long-term homologous and temporary heterologous protection from dengue virus (DENV) infection may be mediated by neutralizing antibodies. However, neutralizing antibody titers (NTs) have not been clearly associated with protection from infection.

Methodology/Principal Findings

Data from two geographic cluster studies conducted in Kamphaeng Phet, Thailand were used for this analysis. In the first study (2004–2007), cluster investigations of 100-meter radius were triggered by DENV-infected index cases from a concurrent prospective cohort. Subjects between 6 months and 15 years old were evaluated for DENV infection at days 0 and 15 by DENV PCR and IgM ELISA. In the second study (2009–2012), …

The Inkwell, Armstrong State University

The Inkwell

No abstract provided.