Digital Commons Network^™

Telomeric Orfs (Tlos) In Candida Spp. Encode Mediator Subunits That Regulate Distinct Virulence Traits, John Haran, Hannah Boyle, Karsten Hokamp, Tim Yeomans, Zhongle Liu, Michael Church, Alastair B. Fleming, Matthew Z. Anderson, Judith Berman, Lawrence C. Meyers, Derek J. Sullivan, Gary P. Morgan

Dartmouth Scholarship

The TLO genes are a family of telomere-associated ORFs in the fungal pathogens Candida albicans and C. dubliniensis that encode a subunit of the Mediator complex with homology to Med2. The more virulent pathogen C. albicans has 15 copies of the gene whereas the less pathogenic species C. dubliniensis has only two (CdTLO1 and CdTLO2). In this study we used C. dubliniensis as a model to investigate the role of TLO genes in regulating virulence and also to determine whether TLO paralogs have evolved to regulate distinct functions. A C. dubliniensis tlo1Δ/tlo2Δ mutant is unable …

News Of The Department Of Animal Science, Department Of Animal Science

Animal Science Newsletters

No abstract provided.

The Weekly Challenger, October 30, 2014, The Weekly Challenger, Et Al

Weekly Challenger Newspaper Collection

The October 30, 2014, issue of The Weekly Challenger.

The Grizzly, October 30, 2014, Rachel Brown, Yongshi Li, Olivia Frymark, Andrew Simoncini, Brian Thomas, Joao Angelotto, Andrew Mackin, Steve Valverde, Rayleen Rivera-Harbach, Allie Cook, Drae Lewis, Gerard Brown

Ursinus College Grizzly Newspaper, 1978 to Present

Board Announces National Search for New President • Residents Relocated After Fire • Clubs Host First Ever "Festifall" • Yik Yak Exposes Use of Fake IDs • Midterm Elections Approaching • Halloween Compared to Other International Holidays • UC Alumni Return • Viewers are Drawn to Colonial Theatre in Phoenixville • Student Interns at Disney World • Opinion: Must Halloween Costumes for Women be Sexy?; Occupy Movement in Hong Kong Persists • Local Athlete Stong Giving Field Hockey a Scoring Spark • Diving Into 2014-15 Slate • Seri-ously Good

Curriculum Minutes 10/30/2014, Curriculum Committee

Curriculum Committee Minutes

In these minutes: Program changes and catalog course change clean-up in the Division of the Social Sciences; Program changes in the Division of Science and Mathematics

Kenyon Collegian - October 30, 2014

The Kenyon Collegian

No abstract provided.

Crystal Clear Volunteers, Jim Graham

UNH Today Archive

No abstract provided.

A Decision Support Model For Personalized Cancer Treatment, Florentino Antonio Rico-Fontalvo

USF Tampa Graduate Theses and Dissertations

This work is motivated by the need of providing patients with a decision support system that facilitates the selection of the most appropriate treatment strategy in cancer treatment. Treatment options are currently subject to predetermined clinical pathways and medical expertise, but generally, do not consider the individual patient characteristics or preferences. Although genomic patient data are available, this information is rarely used in the clinical setting for real-life patient care. In the area of personalized medicine, the advancement in the fundamental understanding of cancer biology and clinical oncology can promote the prevention, detection, and treatment of cancer diseases.

The objectives …

Validation Of Reference Housekeeping Genes For Gene Expression Studies In Western Corn Rootworm (Diabrotica Virgifera Virgifera), Thaís Barros Rodrigues, Chitvan Khajuria, Haichuan Wang, Natalie Matz, Danielle Cunha Cardoso, Fernando Hercos Valicente, Xuguo Zhou, Blair Siegfried

Entomology Faculty Publications

Quantitative Real-time PCR (qRT-PCR) is a powerful technique to investigate comparative gene expression. In general, normalization of results using a highly stable housekeeping gene (HKG) as an internal control is recommended and necessary. However, there are several reports suggesting that regulation of some HKGs is affected by different conditions. The western corn rootworm (WCR), Diabrotica virgifera virgifera LeConte (Coleoptera: Chrysomelidae), is a serious pest of corn in the United States and Europe. The expression profile of target genes related to insecticide exposure, resistance, and RNA interference has become an important experimental technique for study of western corn rootworms; however, lack …

Environment Restoration Operations Consolidated Quarterly Report - October 2014, Sandia National Laboratories/Nm

Environmental Restoration

Environmental Restoration Operations Consolidated Quarterly Report, October 2014 for the Department of Energy, National Nuclear Security Administration, Sandia Corporation that addresses all quarterly reporting (April through June 2014) required under the Hazardous and Solid Waste Amendments Module of the Resource Conservation and Recovery Act Permit, the Compliance Order on Consent and the Chemical Waste Landfill Post-Closure Care Plan for Sandia National Laboratories/New Mexico, Environmental Protection Agency identification number NM5890110518.

Characterization Of Severe Fever With Thrombocytopenia Syndrome In Rural Regions Of Zhejiang, China, Lei Zhang, Ling Ye, David M. Ojcius, Xiuyu Lou, Chengwei Wang, Cen Feng, Yi Sun, Zhongfa Wang, Shibo Li, Yanjun Zhang

All Dugoni School of Dentistry Faculty Articles

Severe fever with thrombocytopenia syndrome virus (SFTSV) infections have recently been found in rural regions of Zhejiang. A severe fever with thrombocytopenia syndrome (SFTS) surveillance and sero-epidemiological investigation was conducted in the districts with outbreaks. During the study period of 2011–2014, a total of 51 SFTSV infection cases were identified and the case fatality rate was 12% (6/51). Ninety two percent of the patients (47/51) were over 50 years of age, and 63% (32/51) of laboratory confirmed cases occurred from May to July. Nine percent (11/120) of the serum samples from local healthy people without symptoms were found to be …

The Colby Echo (2014-10-30), Colby College

The Colby Echo

Published by the students of Colby College since 1877, The Colby Echo is the weekly, editorially independent student-run newspaper of Colby College in Waterville, Maine. Published monthly, 1877-1886; semi-monthly, 1886-1897; and weekly, during the academic year, 1898-present.

Rencana Strategis Pengembangan Pusat Kanker Nasional Indonesia, Sebuah Studi Kasus, Sonar Soni Panigoro

Jurnal ARSI : Administrasi Rumah Sakit Indonesia

Cancer is a chronic disease and its prevalence is increasing nowadays. Uptudate, Indonesia doesn’t have a comprehensive program for National Cancer Control. This study aims to develop a strategic plan for the development of National Cancer Center for Indonesia. This study is conducted by using operational research approach, and is conducted during the months of March to December 2013 by involving various stakeholders. In Indonesia, cancer is the third killer disease among the NCD (Non Communicable Disease), the incidence is increasing as well as the funding for cancer treatment. All informants expressed the importance of establishing a national institute that …

Building On The International Polar Year : D Iscovering Interdisciplinary Data Through Federated Search, L. Yarmey, S.J. Khalsa

Copyright, Fair Use, Scholarly Communication, etc.

The legacy of the International Polar Year 2007 2007–2008 (IPY) includes advances in open data and meaningful progress toward towards interoperability of data, systems, and standards. Enabled by metadata brokering technologies and by the growing adoption of international metadata standards, federated data search welcomes diversity in Arctic data and recognizes the value of expertise in community data repositories repositories. Federated search enables specialized data holdings to be discovered by broader audiences and complements the role of metadata registries such as the Global Change Master Directory, providing interoperability across the Arctic web-of -repositories.

Reproducible Protein Nmr Data Analysis, Matthew Fenwick

Doctoral Dissertations

Nuclear Magnetic Resonance (NMR) spectroscopy is a technique for studying biological molecules such as proteins at the atomic level. The information obtained from NMR is used to identify binding partners, locate active sites and binding pockets, and obtain structural and dynamics information which can be used in drug design. During the analysis process, large amounts of data and meta data are generated. However, much of this is not recorded and thus does not show up in archives such as the Biological Magnetic Resonance Data Bank (BMRB). This raises serious reproducibility concerns, since the data and meta data describing how the …

The Inkwell, Armstrong State University

The Inkwell

No abstract provided.

Wastewater Nutrient Recovery Using Anaerobic Membrane Bioreactor Permeate For Hydroponic Fertigation, Jorge Luis Calabria

USF Tampa Graduate Theses and Dissertations

The imbalance between global population growth and resource consumption is indicative of unsustainable practices and foreshadows a grim future of continued resource depletion, food and water scarcity, social inequality, and deteriorating public and environmental health. Meanwhile, the urban centers of the world continue to experience exponential growth resulting in overwhelmed food, water, and sanitation infrastructure. Decentralized and satellite wastewater treatment technologies capable of resource recovery, such as anaerobic membrane bioreactors (AnMBR), foster synergistic opportunities to help manage the food, energy, and water sectors of urban environments. Specifically, the nutrient concentration and high effluent quality of permeate produced by AnMBR systems …

The Effects Of Emotive Reasoning On Secondary School Students' Decision-Making In The Context Of Socioscientific Issues, Wardell Anthony Powell

USF Tampa Graduate Theses and Dissertations

The discrepancy between what students are being taught within K-12 science classrooms and what they experience in the real world has been well documented. This study sought to explore the ways a high school biology curriculum, which integrates socioscientific issues, impacts students' emotive reasoning and their ability to evaluate evidence, make informed decisions on contemporary scientific dilemmas, and integrate scientific content knowledge in their reasoning on SSI. Both quantitative and qualitative methods were used to examine differences within and between an SSI treatment group and a comparison group as well as individual differences among students' responses over a semester of …

Fabrication And Evaluation Of A Micro(Bio)Sensor Array Chip For Multiple Parallel Measurements Of Important Cell Biomarkers, Roy M. Pemberton, Timothy Cox, Rachel Tuffin, Guido A. Drago, John Griffiths, Robin Pittson, Graham Johnson, Jinsheng Xu, Ian C. Sage, Rhodri Davies, Simon K. Jackson, Gerry Kenna, Richard Luxton, John P. Hart

School of Biomedical Sciences

This report describes the design and development of an integrated electrochemical cell culture monitoring system, based on enzyme-biosensors and chemical sensors, for monitoring indicators of mammalian cell metabolic status. MEMS technology was used to fabricate a microwell-format silicon platform including a thermometer, onto which chemical sensors (pH, O₂) and screen-printed biosensors (glucose, lactate), were grafted/deposited. Microwells were formed over the fabricated sensors to give 5-well sensor strips which were interfaced with a multipotentiostat via a bespoke connector box interface. The operation of each sensor/biosensor type was examined individually, and examples of operating devices in five microwells in parallel, …

The Fifth Season, Nona Caspers

Ontario Review

Nona Caspers' book of stories Heavier Than Air won the AWP Grace Paley Short Fiction Prize and is forthcoming from the University of Massachusetts Press. "The Fifth Season" is adapted from a story in that collection. Her work has also been honored with a Cooper Prize from Ontario Review and an Iowa Fiction Award from the Iowa Review. She teaches at San Francisco State University.

The Influence Of Social Environment And Hypercholesterolemia On Sympathetic Nervous System Innervation Of Vascular Tissue In Rabbits, Crystal M. Noller

Open Access Dissertations

Behavioral and psychosocial factors have been shown to influence cardiovascular disease. While interventions targeting these risk factors demonstrate clinical improvement, mechanisms underlying these effects remain to be determined. Research has also defined a relationship between psychosocial stress and immune function, and revealed stress related increases in lymphatic sympathetic nerve density. Considering that inflammation characterizes the various stages of heart disease, the current study assessed whether social stress could influence vascular sympathetic innervation in the presence or absence of hypercholesterolemia. We found dense sympathetic innervation extending into the vascular media and intima throughout the aortic arch and thorax in diseased as …

2014 October 29 -- Agenda And Attachments

Agendas and Minutes

No abstract provided.

Reply To ‘Co2 Emissions From Crop Residue-Derived Biofuels’, Adam Liska, Haishun Yang, Matthew P. Pelton, Andrew E. Suyker

Adam Liska Papers

The soil organic carbon (SOC) model that we used was parameterized with data from arable land under normal farming conditions in North America, Europe, Africa and Asia, but the equation is insensitive to changes in tillage, soil texture and moisture. The model has reasonable accuracy, however, in predicting changes in SOC, residue remaining and CO₂ emissions from initial SOC, carbon inputs from residue, and daily temperature; the shoot-to-root ratio used in the geospatial simulation was 0.29 (that is, root carbon is 29% of total aboveground carbon), which did not underestimate carbon input to soil (Supplementary Figure 2 in Ref. …

The Cord (October 29, 2014)

The Cord

No abstract provided.

Volume 106 Issue 8, Southwestern Oklahoma State University

The Southwestern - Archive

No abstract provided.

Weekly News Digest 10/29/2014, Jenna Ray

Weekly Bulletin Archive

In This Issue:

● Careers in Biology Welcomes Ian Brown ’04

● Morris a Business Insider Smartest Public College

● Kuchenreuther Named Fourth UMM Founders Scholar

● Chancellor Johnson Appears in Second Nature Video

A Generator-Produced Gallium-68 Radiopharmaceutical For Pet Imaging Of Myocardial Perfusion, Nigam Rath, Vijay Sharma, Jothilingam Sivapackiam, Scott Harpstrite, Julie Prior, Hannah Gu, David Piwnica-Worms

Chemistry & Biochemistry Faculty Works

Lipophilic cationic technetium-99m-complexes are widely used for myocardial perfusion imaging (MPI). However, inherent uncertainties in the supply chain of molybdenum-99, the parent isotope required for manufacturing 99Mo/99mTc generators, intensifies the need for discovery of novel MPI agents incorporating alternative radionuclides. Recently, germanium/gallium (Ge/Ga) generators capable of producing high quality 68Ga, an isotope with excellent emission characteristics for clinical PET imaging, have emerged. Herein, we report a novel 68Ga-complex identified through mechanism-based cell screening that holds promise as a generator-produced radiopharmaceutical for PET MPI.

The Relative Importance Of Number, Duration, And Intensity Of Cold Stress Events In Determining Survival And Energetics Of An Overwintering Insect, Katie E. Marshall, Brent J Sinclair

Biology Publications

1. The relationship between abiotic stress and fitness in an individual is usually described by the intensity and duration of stress. Yet in natural systems, variability in abiotic stress is common. Since individuals have physiological and fitness responses to single bouts of stress, frequency of stress may also determine the lifetime success of an organism. However, the majority of laboratory studies have focused only on the effects of single stress events.
2. We investigated the relative importance of stress parameters including duration, intensity and number of cold events on the short-term physiology and long-term fitness in the freeze-avoiding eastern spruce budworm Choristoneura …

2014 Program, Office Of Academic Affairs

Programs

At its best, a university is a collection of individuals ‐‐ students and faculty ‐‐ focused on learning and discovering new knowledge. For this goal to be realized, a critical element is having faculty members deeply engaged in such discovery within their disciplines. Scholarship, in the form of journal articles, book chapters, monographs and similar endeavors, creative activity which can take an even wider range of forms, and funded research which explores the boundaries of disciplines all contribute to such engagement. Through such participation, faculty members stay at the growing edges of their fields, and in so doing, they enrich …

Improving The Efficacy Of Web-Based Educational Outreach In Ecology, Gregory R. Goldsmith, Andrew D. Fulton, Colin D. Witherill, Javier F. Espeleta

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Scientists are increasingly engaging the web to provide formal and informal science education opportunities. Despite the prolific growth of web-based resources, systematic evaluation and assessment of their efficacy remains limited. We used clickstream analytics, a widely available method for tracking website visitors and their behavior, to evaluate 60,000 visits over three years to an educational website focused on ecology. Visits originating from search engine queries were a small proportion of the traffic, suggesting the need to actively promote websites to drive visitation. However, the number of visits referred to the website per social media post varied depending on the social …