Digital Commons Network^™

Preventing Sleep Deprivation In Shift Nurses: What Is The Best Evidence?, Rhonda D. Wilkins

Theses and Dissertations

Insufficient sleep can lead to a variety of cognitive problems such as impaired learning ability, slow thought processes, slower reaction time, poor mood, risky decision-making, inattention, diminished communication skills, and the danger of falling asleep during critical times. Sleep deprived shift nurses are a risk for making erTors and developing health problems. The purpose of this independent study is to detennine the best evidence to prevent sleep deprivation in shift nurses.

A comprehensive review of the literature was perfonned to detennine best practices of preventing sleep deprivation in shift nurses. Literature searches using CINAHL, Medline, Medline Plus, PubMed, Cochrane Library, …

Ido2 In Immunomodulation And Autoimmune Disease., George C Prendergast, Richard Metz, Alexander J Muller, Lauren M F Merlo, Laura Mandik-Nayak

Department of Microbiology and Immunology Faculty Papers

IDO2 is a relative of IDO1 implicated in tryptophan catabolism and immune modulation but its specific contributions to normal physiology and pathophysiology are not known. Evolutionary genetic studies suggest that IDO2 has a unique function ancestral to IDO1. In mice, IDO2 gene deletion does not appreciably affect embryonic development or hematopoiesis, but it leads to defects in allergic or autoimmune responses and in the ability of IDO1 to influence the generation of T regulatory cells. Gene expression studies indicate that IDO2 is a basally and more narrowly expressed gene than IDO1 and that IDO2 is uniquely regulated by AhR, which …

The Stored Communications Act And Digital Assets, David Horton

Vanderbilt Law Review

This Article explores the impact of federal law on a state fiduciary's management of digital assets. It focuses on the lessons from the Stored Communications Act ("SCA'), initially enacted in 1986 as one part of the Electronic Communications Privacy Act. Although Congress designed the SCA to respond to concerns that Internet privacy posed new dilemmas with respect to application of the Fourth Amendment's privacy protections, the drafters did not explicitly consider how the SCA might affect property management and distribution. The resulting uncertainty affects anyone with an email account. While existing trusts and estates laws could legitimately be interpreted to …

Transhumanism And Catholic Natural Law: Changing Human Nature And Changing Moral Norms?, Brian Patrick Green

Staff Publications and Research

In this chapter I propose a preliminary response to the transhumanist challenge to natural law by investigating six basic questions: ( 1) Is human nature relevant to morality? (2) Is human nature mutable? (3) How would we know if human nature had changed? ( 4) Could cultural evolution replace biological evolution? (5) How would human nature and human will relate to each other under these new transhuman conditions? (6) Is it possible to construct a dynamic ethic to fit a dynamic nature, and if so, what might that ethic be?

Overall, I argue that it is possible to maintain a …

Semi-Synthetic Development Of Mithramycin Analogues, Sterling Brooks, Allison Foster, Daniel Scott

Annual Student Research Poster Session

No abstract provided.

The Feminist-Christian Schism Revisited, Karen Guth

Journal of Scriptural Reasoning

No abstract provided.

Oncolog, Volume 59, Number 11-12, November-December 2014, Bryan Tutt, Sunita Patterson, S. Moreau

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Striving to Improve Treatments for Uveal Melanoma: Although primary uveal melanoma can be effectively treated with radiation or surgery, patients with metastatic disease-or those at high risk for metastases-have few proven options. But specialists in medical oncology, radiation oncology, ophthalmology, surgery, and traditional research are working to improve those options
• Beyond Diabetes: Metformin May Have Broad Utility in Cancer: Metformin, an inexpensive drug that has been prescribed for diabetes for decades, may also be useful in preventing or treating several types of cancer
• HOUSE CALL: Smoking Cessation-Medications help smokers quit
• INBRIEF: Vaccine Explored to Reduce Risk of HER2-Positive Breast Cancer …

An Ecological Model For Digital Platforms Maintenance And Evolution, Paolo Rocchi, Paolo Spagnoletti, Subhajit Datta

Research Collection School Of Computing and Information Systems

The maintenance of software products has been studied extensively in both software engineering and management information systems. Such studies are mainly focused on the activities that take place prior to starting the maintenance phase. Their contribution is either related to the improvement of software quality or to validating contingency models for reducing maintenance efforts. The continuous maintenance philosophy suggests to shift the attention within the maintenance phase for better coping with the evolutionary trajectories of digital platforms. In this paper, we examine the maintenance process of a digital platform from the perspective of the software vendor. Based on our empirical …

Combining Multiple Kernel Methods On Riemannian Manifold For Emotion Recognition In The Wild, M. Liu, R. Wang, S. Li, S. Shan, Zhiwu Huang, X. Chen

Research Collection School Of Computing and Information Systems

In this paper, we present the method for our submission to the Emotion Recognition in the Wild Challenge (EmotiW 2014). The challenge is to automatically classify the emotions acted by human subjects in video clips under realworld environment. In our method, each video clip can be represented by three types of image set models (i.e. linear subspace, covariance matrix, and Gaussian distribution) respectively, which can all be viewed as points residing on some Riemannian manifolds. Then different Riemannian kernels are employed on these set models correspondingly for similarity/distance measurement. For classification, three types of classifiers, i.e. kernel SVM, logistic regression, …

Deep Learning For Content-Based Image Retrieval: A Comprehensive Study, Ji Wan, Dayong Wang, Steven C. H. Hoi, Pengcheng Wu, Jianke Zhu, Yongdong Zhang, Jintao Li

Research Collection School Of Computing and Information Systems

Learning effective feature representations and similarity measures are crucial to the retrieval performance of a content-based image retrieval (CBIR) system. Despite extensive research efforts for decades, it remains one of the most challenging open problems that considerably hinders the successes of real-world CBIR systems. The key challenge has been attributed to the well-known "semantic gap" issue that exists between low-level image pixels captured by machines and high-level semantic concepts perceived by human. Among various techniques, machine learning has been actively investigated as a possible direction to bridge the semantic gap in the long term. Inspired by recent successes of deep …

Nebline, November/December 2014

NEBLINE Newsletter Archive from Nebraska Extension in Lancaster County

Feature: Tiny Tastes Can Total BIG CALORIES Over the Holiday Season

Food & Health

Family Living

Farm & Acreage

Home & Family Living

Horticulture

Pests & Wildlife

4-H & Youth

Extension Calendar

and other extension news and events

Timber Talk, Vol. 52, No. 4, November 1, 2014

Timber Talk: Nebraska Forest Industry Newsletter

In This Issue

Lumber Market News ...........................1

Hardwood Lumber Price Trends—Green..................................2

Hardwood Lumber Price Trends—Kiln Dried...........................2

Wood is Good........................................3

Simple Steps for Double Your Firewood Profits................................4

Homemade Log Forwarder...................5

Nebraska Forest Industry Spotlight......6

The Trading Post....................................8

Timber Sales...........................................8

Depicting The Tree Of Life In Museums: Guiding Principles From Psychological Research, Laura R. Novick, Jane Pickering, Teresa Macdonald, Judy Diamond, Shaaron Ainsworth, Adriana E. Aquino, Kefyn M. Catley, Jeff Dodick, Evelyn Margaret Evans, Camillia Matuk, Janis Sacco, Monique Scott

University of Nebraska State Museum: Programs Information

The Tree of Life is revolutionizing our understanding of life on Earth, and, accordingly, evolutionary trees are increasingly important parts of exhibits on biodiversity and evolution. The authors argue that in using these trees to effectively communicate evolutionary principles, museums need to take into account research results from cognitive, developmental, and educational psychology while maintaining a focus on visitor engagement and enjoyment. Six guiding principles for depicting evolutionary trees in museum exhibits distilled from this research literature were used to evaluate five current or recent museum trees. One of the trees was then redesigned in light of the research while …

A Transcendental Phenomenological Study Of Developmental Math Students' Experiences And Perceptions, Megan Cordes

Doctoral Dissertations and Projects

Current literature suggests the rise of enrollment among United States (U.S.) postsecondary institutions but the decline in graduation rates. While there is extensive quantitative data examining course redesigns and increasing student achievement in developmental math courses, there is limited research examining students' experiences and perceptions within these courses. The purpose of this transcendental phenomenological study was to examine the experiences and perceptions of developmental math students. This study utilized the theoretical framework of Bandura's (1997) social cognitive theory and Tinto's (2012a) retention theory. Research questions focused on the lived experience of struggling within a developmental math course, past math experiences …

Post-Hurricane Fuel Dynamics And Forest Regeneration Of Coastal Pine Stands In Southeast United States, Shanyue Guan

All Theses

Hurricanes have long been powerful and recurring disturbances in many coastal forest ecosystems. Intense hurricanes often produce a large amount of dead fuels within their affected forests, but how post-hurricane fuel complex changes with time, due to decomposition and management such as salvage, and the fire behavior affected by the changed fuel load remains largely unknown. To better understand the fuel and regeneration dynamics, field measurement and modeling were conducted within undamaged stands and hurricane damaged stands, including salvaged and unsalvaged stands in southern pine forests impacted by hurricane Hugo (1989), Opal (1995), Katrina (2005), and Ike (2008). We found …

The Paradoxes Of Public Philosophy, Brian Leiter

Public Law and Legal Theory Working Papers

No abstract provided.

Hypoxic Stress Induces, But Cannot Sustain Trophoblast Stem Cell Differentiation To Labyrinthine Placenta Due To Mitochondrial Insufficiency, Yufen Xie, Sichang Zhou, Zhongliang Jiang, Jing Dai, Elizabeth E. Puscheck, Icksoo Lee, Graham Parker, Maik Hüttemann, Daniel A. Rappolee

Department of Obstetrics and Gynecology Research Publications

Dysfunctional stem cell differentiation into placental lineages is associated with gestational diseases. Of the differentiated lineages available to trophoblast stem cells (TSC), elevated O2 and mitochondrial function are necessary to placental lineages at the maternal–placental surface and important in the etiology of preeclampsia. TSC lineage imbalance leads to embryonic failure during uterine implantation. Stress at implantation exacerbates stem cell depletion by decreasing proliferation and increasing differentiation. In an implantation site O2 is normally ~ 2%. In culture, exposure to 2% O2 and fibroblast growth factor 4 (FGF4) enabled the highest mouse TSC multipotency and proliferation. In contrast, hypoxic stress (0.5% …

Can Protected Bike Lanes Help Close The Gender Gap In Cycling? Lessons From Five Cities, Jennifer Dill, Tara Goddard, Christopher Monsere, Nathan Mcneil

Urban Studies and Planning Faculty Publications and Presentations

Even in areas with increased levels of bicycling, there remains a significant “gender gap” in bicycling in the United States, in contrast to many other countries with high rates of bicycling. The primary objective of this paper was to explore whether protected bike lanes could help reduce the gender gap. To do so, the authors used survey data from a comprehensive evaluation of protected bike lanes in five large U.S. cities (Austin, TX, Chicago, IL, Portland, OR, San Francisco, CA, and Washington, DC) that included survey responses of 1,111 intercepted bicyclists and 2,283 residents. Both men and women overwhelmingly felt …

The Dilemma Of Foraging Herbivores: Dealing With Food And Fear, Clare Mcarthur, Peter B. Banks, Rudy Boonstra, Jennifer Sorensen Forbey

Biology Faculty Publications and Presentations

For foraging herbivores, both food quality and predation risk vary across the landscape. Animals should avoid low-quality food patches in favour of high-quality ones, and seek safe patches while avoiding risky ones. Herbivores often face the foraging dilemma, however, of choosing between high-quality food in risky places or low-quality food in safe places. Here, we explore how and why the interaction between food quality and predation risk affects foraging decisions of mammalian herbivores, focusing on browsers confronting plant toxins in a landscape of fear. We draw together themes of plant–herbivore and predator–prey interactions, and the roles of animal ecophysiology, behaviour …

Osr1 Is Required For Podocyte Development Downstream Of Wt1a, Ritu Tomar, Sudha P. Mudumana, Narendra Pathak, Neil A. Hukriede, Iain A. Drummond

Neuroscience: Faculty Publications

Odd-skipped related 1 (Osr1) encodes a zinc finger transcription factor required for kidney development. Osr1 deficiency in mice results in metanephric kidney agenesis, whereas knockdown or mutation studies in zebrafish revealed that pronephric nephrons require osr1 for proximal tubule and podocyte development. osr1-deficient pronephric podocyte progenitors express the Wilms' tumor suppressor wt1a but do not undergo glomerular morphogenesis or express the foot process junctional markers nephrin and podocin. The function of osr1 in podocyte differentiation remains unclear, however. Here, we found by double fluorescence in situ hybridization that podocyte progenitors coexpress osr1 and wt1a. Knockdown of wt1a disrupted podocyte differentiation …

Rnase L Interacts With Filamin A To Regulate Actin Dynamics And Barrier Function For Viral Entry, Krishnamurthy Malathi, Mohammad Adnan Siddiqui, Shubham Dayal, Merna Naji, Heather J, Ezelle, Chun Zeng, Aimin Zhou, Bret A. Hassel

Chemistry Faculty Publications

The actin cytoskeleton and its network of associated proteins constitute a physical barrier that viruses must circumvent to gain entry into cells for productive infection. The mechanisms by which the physical signals of infection are sensed by the host to activate an innate immune response are not well understood. The antiviral endoribonuclease RNase L is ubiquitously expressed in a latent form and activated upon binding 2-5A, a unique oligoadenylate produced during viral infections. We provide evidence that RNase L in its inactive form interacts with the actin-binding protein Filamin A to modulate the actin cytoskeleton and inhibit virus entry. Cells …

Effect Of Grain, Region, And Human Influence On Higher Taxonomic Surrogacy, Frances Owen

Master's Theses or Doctor of Nursing Practice

Surrogacy is a common tool within conservation and can be useful when scientists lack detailed knowledge of a system. Higher taxonomic surrogacy is appealing because it can save time and money. However, this technique might vary in effectiveness depending on the taxonomic level, spatial grain, region, and impact by humans. In this thesis I addressed some of the common concerns with higher taxonomic surrogacy using Breeding Bird Atlas data from six states (Colorado, Florida, Michigan, New York, Pennsylvania, and Washington). I compared the coefficients (slopes) of my models rather than the R2 values relied on by other higher taxonomic surrogacy …

Age, Growth, And Simulation Modeling To Characterize Fish Populations At Two Reservoirs In South-Central Kansas, Brian Serpan

Master's Theses or Doctor of Nursing Practice

Several fish populations in Kansas are heavily exploited. To obtain insight into the response of fish populations to management actions, fisheries biologists must obtain as much information as possible with limited resources. To address these challenges, biologists often use age and growth information to understand the age structure of the populations, estimate recruitment and mortality, and gain insight into environmental and genetic factors influencing growth. In addition, age and growth data are used to generate yield-per-recruit models, which allow biologists to extrapolate population trends and make broad predictions about population responses to different management actions. Cheney and El Dorado reservoirs …

In The Shadow Of Tolerance: The Discursive Context Of Dutch-Born Muslim Youth, Mayida Zaal

Department of Secondary and Special Education Scholarship and Creative Works

Despite a public discourse on tolerance, anxiety about immigrants, Islam and the preservation of Dutch values has amplified fear of Muslim youth in the Netherlands. In this context, Dutch-born Muslim youth endure social and systemic discrimination that affects all aspects of their futures, including available educational opportunities and eventually their prospects for employment. ased on a one-year qualitative study conducted in Amsterdam, this article explores the lived experience of Dutch-born Muslim youth caught at the intersection of national policies and local realities. Grounded in critical literature originating in the Netherlands and in Europe, this inquiry triangulates participant observations, focus groups …

Er-Associated Degradation And Cadmium Dependent Rescue Of Pca1, Nathan Smith

Department of Biochemistry: Dissertations, Theses, and Student Research

Protein synthesis and proper folding is an essential process for all organisms. In eukaryotes proteins of the secretory pathway are synthesized and inserted into the lumen or membrane of the endoplasmic reticulum. Eukaryotic cells maintain a mechanism for removal of proteins unable to fold properly. This process is known as ER-associated degradation (ERAD). A poorly functioning ERAD can lead to a build-up of misfolded proteins which has been implicated in several degenerative diseases such as Alzheimer’s, Amyotrophic lateral sclerosis, and Parkinson’s. Thus, the study of how proteins are recognized, extracted from the ER, and degraded is essential for determining methods …

Close On The Wind: An Environmental Military History Examining Wind’S Influence On The Early United States Navy, Scott J. Beehler

Department of History: Dissertations, Theses, and Student Research

Utilizing General Carl von Clausewitz’s theory of friction in combat, Close on the Wind examines wind’s historical influence on early United States naval warfare, specifically small scale engagements fought during the Quasi War, First Barbary War, and the War of 1812. To accomplish this, the thesis first engages in a scientific discussion of wind, concentrating on how it occurs and what forces dictate its velocity and direction. The examination goes on to also present the types of wind that period sailing vessels encountered, including global, regional, and local patterns, as well as how wind influenced the practice of sailing and …

Hydrolytically Stable Analogues Of Sugar Phosphates And A Miniaturized In Situ Enzymatic Screen, Xiang Fei

Department of Chemistry: Dissertations, Theses, and Student Research

The glmS riboswitch undergoes self-cleavage upon binding its metabolic product GlcN6P, thereby providing a negative feedback mechanism limiting translation of the glmS protein when GlcN6P is abundant. As a first step toward the development of novel antimicrobials, we have synthesized a series of GlcN6P analogues bearing phosphatase-inert surrogates in place of the natural phosphate ester functionality. The self-cleavage assay identified two such compounds that display significant riboswitch actuator activity; namely those bearing a 6-phosphonomethyl group or a 6-O-malonyl ether. These two analogues exhibit a 22-fold and a 27-fold higher catalytic efficiency, respectively, than does glucosamine. Docking experiments were …

Beneath The Forest, Volume 7, No. 2, Fall 2014, Johanna L. Kovarik

Beneath the Forest

Contents: Alpine Caves of Turtlehead Mountains - Rare and Uncommon Plants of Rockhouses: Episode Two - Returning to the Caves of the Monongahela National Forest: Alpha Door Cave - Underground for Four Days!

Project Holly: Can Human-Based Behavioral Therapy Help A Chimpanzee?, Ellen Ingmanson

Bridgewater Review

No abstract provided.

How Fun Are Your Meetings? Investigating The Relationship Between Humor Patterns In Team Interactions And Team Performance, Nale Lehmann-Willenbrock, Joseph A. Allen

Psychology Faculty Publications

Research on humor in organizations has rarely considered the social context in which humor occurs. One such social setting that most of us experience on a daily basis concerns the team context. Building on recent theorizing about the humor—performance association in teams, this study seeks to increase our understanding of the function and effects of humor in team interaction settings. Specifically, we examine behavioral patterns of humor and laughter in real teams. We videotaped and coded humor and laughter during 54 regular organizational team meetings. Performance ratings were obtained immediately following the team meetings as well as at a later …