Digital Commons Network^™

Alpha-Asarone Protects Endothelial Cells From Injury By Angiotensin Ii, Ha-Xia Shi, Jiajun Yang, Tao Yang, Yong-Liang Xue, Jun Liu, Ya-Juan Li, Dan-Dan Zhang, Ji-Wen Zhu, Ka Bian

Biochemistry and Molecular Medicine Faculty Publications

α-Asarone is the major therapeutical constituent of Acorus tatarinowii Schott. In this study, the potential protective effects of α-asarone against endothelial cell injury induced by angiotensin II were investigated in vitro. The EA.hy926 cell line derived from human umbilical vein endothelial cells was pretreated with α-asarone (10, 50, 100 µmol/L) for 1 h, followed by coincubation with Ang II (0.1 µmol/L) for 24 h. Intracellular nitric oxide (NO) and reactive oxygen species (ROS) were detected by fluorescent dyes, and phosphorylation of endothelial nitric oxide synthase (eNOS) at was determined by Western blotting. α-Asarone dose-dependently mitigated the Ang II-induced intracellular NO …

Census-Based Rapid And Accurate Metagenome Taxonomic Profiling, Amirhossein Shamsaddini, Yang Pan, W. Evan Johnson, Konstantinos Krampis, Mariya Shcheglovitova, Vahan Simonyan, Amy Zanne, Raja Mazumder

Biochemistry and Molecular Medicine Faculty Publications

Background

Understanding the taxonomic composition of a sample, whether from patient, food or environment, is important to several types of studies including pathogen diagnostics, epidemiological studies, biodiversity analysis and food quality regulation. With the decreasing costs of sequencing, metagenomic data is quickly becoming the preferred typed of data for such analysis.

Results

Rapidly defining the taxonomic composition (both taxonomic profile and relative frequency) in a metagenomic sequence dataset is challenging because the task of mapping millions of sequence reads from a metagenomic study to a non-redundant nucleotide database such as the NCBI non-redundant nucleotide database (nt) is a computationally intensive …

Retirees Look Back, Linfield Magazine Staff

Linfield Magazine

Seven retirees share fond memories of their years at Linfield.

'Cat Tracks, Linfield Magazine Staff

Linfield Magazine

News briefs and updates about student athletes, coaches, and alumni

Using The Spatial Variability Of Lead In Urban Soils And Demographic Variables To Predict Exposure Risks: An Environmental Justice Analysis In Terre Haute, Indiana, Heather A. Foxx

All-Inclusive List of Electronic Theses and Dissertations

Terre Haute, Indiana, is similar to many older cities throughout the United States with a history of manufacturing and industry that relied on extensive road and rail networks. This industrial history has resulted in the presence of over 20 brownfields and even a Superfund Site within the city today. Historic neighborhoods and abundance of pre-1950's homes is another characteristic of the city. Unfortunately, improper removal and deterioration of lead (Pb) paints, as well as high Pb solder used in gutters, appear to be significant sources of soil Pb in Terre Haute. Despite the fact that most new environmental sources of …

A Study Of Gene Expression In Legionella Pneumophila Biofilms Through The Use Of Confocal Microscopy, D. Limbaugh, T. Mcnealy

Focus on Creative Inquiry

Legionella pneumophila is the causative agent of Legionnaires' Disease. L. pneumophila is ubiquitous in freshwater environments as well as in man-made water systems such as air conditioners and cooling towers. Legionella biofilms in these systems have been identified as the source of a number of outbreaks. Gene expression in planktonic phase L. pneumophila has been well characterized but little analysis has been conducted within biofilms. We hypothesize that gene expression in Legionella biofilms will exhibit unique expression patterns as compared to planktonic cells. To test this hypothesis Legionella were transformed with reporter gene vectors and biofilms grown on glass slides …

Virginia Commonwealth University Fall Commencement Program [2014], Virginia Commonwealth University

VCU Commencement Programs

No abstract provided.

Table Of Contents

Madison Magazine

No abstract provided.

Madison Vision Series

Madison Magazine

No abstract provided.

Lindenwood Edge, 2014, Lindenwood University

University Documents

No abstract provided.

Weber River Watershed Plan, The Weber River Partnership

All In-stream Flows Material

Our watershed is defined by the people that live, work, and play within its boundaries, as well as the social, ecological, financial and societal benefits that it provides. The Weber River Watershed has experienced a long history of human-influenced changes and alterations in order to enhance human well-being. Many of these actions have enhanced water transportation and delivery, developed sources of hydropower, reduced flood hazards, and provided agricultural, municipal and industrial water supplies (National Research Council 1992), all of which are essential to our survival and quality of life. At the same time, some of those enhancements have had unforeseen …

Prologemena To An Future Rhetoric Of Shadows, Shades And Silhouettes, Gene Washington

English Faculty Publications

In this essay, following the implications of "prolegomena" (Greek: "to say before"), i describe what a rhetoric constructed of textual shadows (the word "shadow" in a text) would look like. Specifically, what would be the various motives and rhetorical intentions, for a writer (of all genres) to employ the word "shadow" or a member of its semantic "family."

2014 Projects Day Booklet, Seattle University

Projects Day Booklets

No abstract provided.

National Security Law, James D. Carlson, Geoffrey M. Goodale, Michael Grant, Michael J. Lowell, Robert Iii Mchugh, Jonathan Michael Meyer, Guy C. Quinlan, Sergio L. Suarez

The International Lawyer

No abstract provided.

Helping Children Find A Home That Offers Safety, Stability, And Love, D'Nique Melissa Stevens

Social Work Theses

The researcher wanted to look closely to see if preferences of adoptive parents, such as a particular race, age, or gender of the adoptee, helped or hindered the process of adoption. Gathering research, based on previous studies, the researcher was able to compare and contrast, to see if there are any patterns regarding adoptive parent preferences. There was a hole in the literature in regards to the preference of gender. This was a quantitative descriptive study completed by Providence College students, using a Likert-like style instrument. The main findings in the research was the statistically significant relationship of the values …

Sjsu Erfa News, Spring 2014, San Jose State University, Emeritus And Retired Faculty Association

Emeritus and Retired Faculty Association (ERFA) Newsletter

Volume 27, Number 3

Identification Of Quantitative Trait Loci (Qtl) Underlying Protein, Oil, And Five Major Fatty Acids’ Contents In Soybean, Masum Akond, Shiming Liu, Melanie Boney, Stella K. Kantartzi, Khalid Meksem, Nacer Bellaloui, David A. Lightfoot, My Abdelmajid Kassem

Articles

Improved seed composition in soybean [Glycine max (L.) Merr.] for protein and oil quality is one of the major goals of soybean breeders. A group of genes that act as quantitative traits with their effects can alter protein, oil, palmitic, stearic, oleic, linoleic, and linolenic acids percentage in soybean seeds. The objective of this study was to identify Quantitative Trait Loci (QTL) controlling protein, oil, and fatty acids content in a set of F5:8 RILs de-rived from a cross between lines, ‘MD 96-5722’ and ‘Spencer’ using 5376 Single Nucleotide Polymorphism (SNP) markers from the Illumina Infinium SoySNP6K BeadChip array. …

Ohio's Current Agricultural Use Value Program: Eligibility, Recoupment And Current Issues, Allen Prindle

Business, Accounting and Economics Faculty Scholarship

This paper examines several issues related to Ohio’s Current Agricultural Use Value (CAUV) Program. Based on data from 2002-10, an average of $6.6 million was collected in recoupment payments per year, because the land was no longer eligible for the benefits of lower real estate taxation. The year with the maximum recoupment payments was 2005. Data from Ohio Department of Taxation appear to be incomplete and to underestimate the actual payments. Other issues related to CAUV eligibility were introduced to update readers and policy makers.

2014 Annual Campus Security And Fire Safety Report, Larry Banaszak

Otterbein Police Department

The report is designed to provide you with important information about security and fire safety on campus. In addition to outlining the details of the many safety programs Otterbein offers its community members, the report also contains statistics about reported crimes and fire safety initiatives on campus.

Terryl Givens, Fiona Givens, And The Rehabilitation Of Mormon Theology, Matthew Bowman

Mormon Studies Review

No abstract provided.

Morehead State University - Students, Jack D. Ellis

Jack D. Ellis Rowan County History Collection

No abstract provided.

Schools - Roy E. Cornette, Jack D. Ellis

Jack D. Ellis Rowan County History Collection

No abstract provided.

Compulsory Dna Collection And A Juvenile's Best Interests, Kevin Lapp

University of Maryland Law Journal of Race, Religion, Gender and Class

No abstract provided.

9th Susquehanna River Symposium Program With Abstracts, Bucknell Center For Sustainability And The Environment

Susquehanna River Symposium -- Conference materials

No abstract provided.

Bmp2 Induced Osteogenic Differentiation Of Human Umbilical Cord Stem Cells In A Peptide-Based Hydrogel Scaffold, Shruthi Lakshmana

Student Theses, Dissertations and Capstones

Craniofacial tissue loss due to traumatic injuries and congenital defects is a major clinical problem around the world. Cleft palate is the second most common congenital malformation in the United States occurring with an incidence of 1 in 700. Some of the problems associated with this defect are feeding difficulties, speech abnormalities and dentofacial anomalies. Current treatment protocol offers repeated surgeries with extended healing time. Our long-term goal is to regenerate bone in the palatal region using tissue-engineering approaches. Bone tissue engineering utilizes osteogenic cells, osteoconductive scaffolds and osteoinductive signals. Mesenchymal stem cells derived from human umbilical cord (HUMSCs) are …

The Ethical Relationship Between School Violence And Teacher Morale, Jennifer O'Connor Duffy, Edward Mooney Jr.

Pedagogy and the Human Sciences

This study explores how negative school climate factors, such as classroom violence, can influence a teacher’s pedagogical approach to classroom learning and relationships with students using a transformative lens to improve student engagement and pedagogical approaches after such tragedies occur. The Burke-Litwin (2010) model of organizational climate is used as a framework to understand how a school's organizational climate contributes to a positive learning culture for teachers, post-trauma, with the goal of heightening teachers’ ability to continue to teach and to maintain student engagement post-violence. Major conclusions show that the underlying school climate plays a critical role in how a …

Morehead State University - Sports, Jack D. Ellis

Jack D. Ellis Rowan County History Collection

No abstract provided.

Morehead State University - Administration & Faculty, Jack D. Ellis

Jack D. Ellis Rowan County History Collection

No abstract provided.

Integrated Assessment Of Predicted Mhc Binding And Cross-Conservation With Self Reveals Patterns Of Viral Camouflage, Lu He, Anne S. Degroot, Andres H. Gutierrez, William D. Martin, Lenny Moise, Chris Bailey-Kellogg

Institute for Immunology and Informatics Faculty Publications

Background

Immune recognition of foreign proteins by T cells hinges on the formation of a ternary complex sandwiching a constituent peptide of the protein between a major histocompatibility complex (MHC) molecule and a T cell receptor (TCR). Viruses have evolved means of "camouflaging" themselves, avoiding immune recognition by reducing the MHC and/or TCR binding of their constituent peptides. Computer-driven T cell epitope mapping tools have been used to evaluate the degree to which particular viruses have used this means of avoiding immune response, but most such analyses focus on MHC-facing 'agretopes'. Here we set out a new means of evaluating …

Vaxcelerate Ii: Rapid Development Of A Self-Assembling Vaccine For Lassa Fever, Pierre Leblanc, Leonard Moise, Cybelle Luza, Kanawat Chantaralawan, Lynchy Lezeau, Jianping Yuan, Mary Field, Daniel Richer, Christine Boyle, William D. Martin, Jordan B. Fishman, Eric A. Berg, David Baker, Brandon Zeigler, Dale E. Mais, William Taylor, Russell Coleman, H. Shaw Warren, Jeffrey A. Gelfand, Anne S. De Groot, Timothy Brauns, Mark C. Poznansky

Institute for Immunology and Informatics Faculty Publications

Development of effective vaccines against emerging infectious diseases (EID) can take as much or more than a decade to progress from pathogen isolation/identification to clinical approval. As a result, conventional approaches fail to produce field-ready vaccines before the EID has spread extensively. Lassa is a prototypical emerging infectious disease endemic to West Africa for which no successful vaccine is available. We established the VaxCelerate Consortium to address the need for more rapid vaccine development by creating a platform capable of generating and pre-clinically testing a new vaccine against specific pathogen targets in less than 120 d. A self-assembling vaccine is …