Digital Commons Network^™

January 21st 2014, Csusb

Coyote Chronicle (1984-)

No abstract provided.

January 21, 2014, James Madison University

The Breeze, 2010-2019

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

Aauw Chapter Awarded Grant For Tech Savvy Program For Girls, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

As Student Gets Mlk Scholarship In Canton, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Pbio Colloquium | The Other 90 Intergenic Heterochromatin Landscapes Of The Maize Genome, Jan 24, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Rna Viral Metagenome Of Whiteflies Leads To The Discovery And Characterization Of A Whitefly-Transmitted Carlavirus In North America, Karyna Rosario, Heather Capobianco, Terry Fei Fan Ng, Mya Breitbart, Jane E. Polston

Marine Science Faculty Publications

Whiteflies from the Bemisia tabaci species complex have the ability to transmit a large number of plant viruses and are some of the most detrimental pests in agriculture. Although whiteflies are known to transmit both DNA and RNA viruses, most of the diversity has been recorded for the former, specifically for the Begomovirus genus. This study investigated the total diversity of DNA and RNA viruses found in whiteflies collected from a single site in Florida to evaluate if there are additional, previously undetected viral types within the B. tabaci vector. Metagenomic analysis of viral DNA extracted from the whiteflies only …

Scholastic Minutes 01/21/2014, Scholastic Committee

Scholastic Committee

The meeting included a brief update on the Writing for the Liberal Arts general education requirement; a SCEP report on the Twin Cities' writing enriched curriculum; a suspension and probation summary; and preparation for the scheduled International Students Program presentation.

Peptide Detection Of Fungal Functional Amyloids In Infected Tissue, Melissa C. Garcia-Sherman, Nataliya Lysak, Alexandra Filonenko, Hazel Richards, Richard E. Sobonya, Stephen A. Klotz, Peter N. Lipke

Publications and Research

Many fungal cell adhesion proteins form functional amyloid patches on the surface of adhering cells. The Candida albicans Agglutinin-like sequence (Als) adhesins are exemplars for this phenomenon, and have amyloid forming sequences that are conserved between family members. The Als5p amyloid sequence mediates amyloid fibril formation and is critical for cell adhesion and biofilm formation, and is also present in the related adhesins Als1p and Als3p. We have developed a fluorescent peptide probe containing the conserved Als amyloid-forming sequence. This peptide bound specifically to yeast expressing Als5p, but not to cells lacking the adhesin. The probe bound to both yeast …

Superoxide Signaling In Perivascular Adipose Tissue Promotes Age-Related Artery Stiffness, Bradley S. Fleenor, Jason S. Eng, Amy L. Sindler, Bryant T. Pham, Jackson D. Kloor, Douglas R. Seals

Graduate Center for Nutritional Sciences Faculty Publications

We tested the hypothesis that superoxide signaling within aortic perivascular adipose tissue (PVAT) contributes to large elastic artery stiffening in old mice. Young (4-6 months), old (26-28 months), and old treated with 4-Hydroxy-2,2,6,6-tetramethylpiperidine 1-oxyl (TEMPOL), a superoxide scavenger (1 mm in drinking water for 3 weeks), male C57BL6/N mice were studied. Compared with young, old had greater large artery stiffness assessed by aortic pulse wave velocity (aPWV, 436 ± 9 vs. 344 ± 5 cm s(-1)) and intrinsic mechanical testing (3821 ± 427 vs. 1925 ± 271 kPa) (both P < 0.05). TEMPOL treatment in old reversed both measures of arterial stiffness. Aortic PVAT superoxide production was greater in old (P < 0.05 vs. Y), which was normalized with TEMPOL. Compared with young, old controls had greater pro-inflammatory proteins in PVAT-conditioned media (P < 0.05). Young recipient mice transplanted with PVAT from old compared with young donors for 8 weeks had greater aPWV (409 ± 7 vs. 342 ± 8 cm s(-1)) and intrinsic mechanical properties (3197 ± 647 vs. 1889 ± 520 kPa) (both P < 0.05), which was abolished with TEMPOL supplementation in old donors. Tissue-cultured aortic segments from old in the presence of PVAT had greater mechanical stiffening compared with old cultured in the absence of PVAT and old with PVAT and TEMPOL (both, P < 0.05). In addition, PVAT-derived superoxide was associated with arterial wall hypertrophy and greater adventitial collagen I expression with aging that was attenuated by TEMPOL. Aging or TEMPOL treatment did not affect blood pressure. Our findings provide evidence for greater age-related superoxide production and pro-inflammatory proteins in PVAT, and directly link superoxide signaling in PVAT to large elastic artery stiffness.

Fsec Meeting Minutes January 21, 2014, University Of Rhode Island Faculty Senate

Faculty Senate Executive Committee Minutes

No abstract provided.

Emu Today, January 21, 2014, Eastern Michigan University

EMU Today

No abstract provided.

Regulation Of Growth And Stress Tolerance In Tomato Plants By Expression Of A Dominant-Negative Version Of Erecta Gene From Arabidopsis Thaliana, Hector Ernesto Villagarcia

Theses and Dissertations

Receptor kinases are the main group of signal recognition structures in plants. The large number and diversity of these receptors suggest that they perform major roles in a complex regulatory network of growth, development, and physiological responses. The ERECTA gene is a leucine-rich, receptor-like kinase that affects plant growth rates, stomatal patterning, transpiration efficiency, bacterial pathogen resistance, inflorescence and floral organ morphology, and leaf polarity. The ability to manipulate the ERECTA pathway in members of the Solanaceae family can reveal fundamental mechanisms including regulation of fruit and tuber development. This knowledge may enable changes in plant architecture and growth rates …

Silica-Based Antibacterial And Antifungal Nanoformulation Div, Swadeshmukul Santra

UCF Patents

A silica-based nanoformulation and method is used to treat citrus canker, inhibit the growth of mold and mildew, and add nutrients to soil used for agricultural purposes. The nanotechnology-enabled copper-loaded, silica nanoformulation (CuSiNP/NG) design is a "revolutionary re-invention" of Cu for safe application because it provides a formulation with maximum abundance ionic Cu, provides sustained and optimal Cu ion release for long-term disease protection, better adherence to plant surfaces and structural surfaces due to gel-based nanostructureof CuSiNG, thus avoiding multiple spray applications and reducing the amount of Cu used in comparison to existing Cu compounds without compromising anitbaterial activity. Thus, …

A Genome-Wide Association Study Identifies A Locus On Tert For Mean Telomere Length In Han Chinese., Yun Liu, Lan Cao, Zhiqiang Li, Daizhan Zhou, Wanqing Liu, Qin Shen, Yanting Wu, Dan Zhang, Xun Hu, Ting Wang, Junyi Ye, Xiaoling Weng, Hong Zhang, Di Zhang, Zhou Zhang, Fatao Liu, Lin He, Yongyong Shi

Borch Department of Medicinal Chemistry and Molecular Pharmacology Faculty Publications

Leukocyte telomere length (LTL) is a predictor of aging and a number of age-related diseases. We performed genome-wide association studies of mean LTL in 2632 individuals,with a two-stage replication in 3917 individuals from Chinese populations. To further validate our findings, we get the results of 696 samples from a cohort of European ancestry. We identified two loci associated with LTL that map in telomerase reverse transcriptase (TERT; rs2736100, P = 1.93×10−5) on chromosome 5p15.33 and near keratin 80 (KRT80; rs17653722, P = 6.96×10−6) on 12q13.13. In Chinese population each C allele of rs2736100 and T allele …

Chronic Proliferative Dermatitis In Sharpin Null Mice: Development Of An Autoinflammatory Disease In The Absence Of B And T Lymphocytes And Il4/Il13 Signaling., Christopher S. Potter, Zhe Wang, Kathleen A. Silva, Victoria E. Kennedy, Timothy M. Stearns, Lisa Burzenski, Leonard D. Shultz, Harm Hogenesch, John P. Sundberg

Department of Comparative Pathobiology Faculty Publications

SHARPIN is a key regulator of NFKB and integrin signaling. Mice lacking Sharpin develop a phenotype known as chronic proliferative dermatitis (CPDM), typified by progressive epidermal hyperplasia, apoptosis of keratinocytes, cutaneous and systemic eosinophilic inflammation, and hypoplasia of secondary lymphoid organs. Rag1−/− mice, which lack mature B and T cells, were crossed with Sharpin−/− mice to examine the role of lymphocytes in CDPM. Although inflammation in the lungs, liver, and joints was reduced in these double mutant mice, dermatitis was not reduced in the absence of functional lymphocytes, suggesting that lymphocytes are not primary drivers of the inflammation in the …

An Intestinal Commensal Symbiosis Factor Controls Neuroinflammation Via Tlr2-Mediated Cd39 Signalling, Yan Wang, Kiel M. Telesford, Javier Ochoa-Repáraz, Sakhina Haque-Begum, Marc Christy, Eli J. Kasper, Li Wang, Yan Wu, Simon C. Robson, Dennis L. Kasper, Lloyd H. Kasper

Dartmouth Scholarship

The mammalian immune system constitutively senses vast quantities of commensal bacteria and their products through pattern recognition receptors, yet excessive immune reactivity is prevented under homeostasis. Intestinal microbiome can influence host susceptibility to extra-intestine autoimmune disorders. Here we report that polysaccharide A (PSA), a symbiosis factor for human intestinal commensal Bacteroides fragilis, protects against central nervous system demyelination and inflammation during experimental autoimmune encephalomyelitis (EAE), an animal model for multiple sclerosis, through toll-like receptor 2 (TLR2). TLR2 mediates tissue-specific expansion of a critical regulatory CD39+ CD4 T cell subset by PSA. Ablation of CD39 signaling abrogates PSA control of EAE …

The Brain’S Response To Physical Activity Studied With Fmri, Ren Weidman, Dr. Travis Oliphant

Journal of Undergraduate Research

In recent years the fields of medicine and physiological research have made many advancements as a result of application of technology. One example of this is the device known as the Magnetic Resonance Imaging machine (MRI). MRI machines use innovative methods based on principles of physics and electronics to effectively attain a cross-sectional view of the human body. The MRI machine emits an electromagnetic field in the presence of a static field to manipulate the nuclear spin of hydrogen atoms in the body. The received signal can then be interpreted and reconstructed to plot a picture of the section examined. …

The George-Anne, Georgia Southern University

The George-Anne

• 'Moving Forward in Unity'
• News
• Opinions
• Arts & Entertainment
• Classifieds
• Puzzles & Comics
• Sports

Secrets And Lies: A New Ohio Law Opens The Adoption Closet, Joanna L. Grossman

Hofstra Law Faculty Scholarship

Under a newly enacted law, adult adoptees in Ohio can now seek access to their original birth certificates. With this change, Ohio joins a small number of states that have made an about-face in thinking about the role of secrecy in adoption, and have joined the gradual shift towards greater openness.

A Novel Evolutionary Strategy Revealed In The Phaeoviruses, K Stevens, K Weynberg, C Bellas, S Brown, Et Al

School of Biological and Marine Sciences

Phaeoviruses infect the brown algae, which are major contributors to primary production of coastal waters and estuaries. They exploit a Persistent evolutionary strategy akin to a K- selected life strategy via genome integration and are the only known representatives to do so within the giant algal viruses that are typified by r- selected Acute lytic viruses. In screening the genomes of five species within the filamentous brown algal lineage, here we show an unprecedented diversity of viral gene sequence variants especially amongst the smaller phaeoviral genomes. Moreover, one variant shares features from both the two major sub-groups within the phaeoviruses. …

A Glycosaminoglycan Based, Modular Tissue Scaffold System For Rapid Assembly Of Perfusable, High Cell Density, Engineered Tissues, Ramkumar Tiruvannamalai-Annamalai, David Randall Armant, Howard W. T Matthew

Biomedical Engineering Faculty Research Publications

The limited ability to vascularize and perfuse thick, cell-laden tissue constructs has hindered efforts to engineer complex tissues and organs, including liver, heart and kidney. The emerging field of modular tissue engineering aims to address this limitation by fabricating constructs from the bottom up, with the objective of recreating native tissue architecture and promoting extensive vascularization. In this paper, we report the elements of a simple yet efficient method for fabricating vascularized tissue constructs by fusing biodegradable microcapsules with tunable interior environments. Parenchymal cells of various types, (i.e. trophoblasts, vascular smooth muscle cells, hepatocytes) were suspended in glycosaminoglycan (GAG) solutions …

Plasma Selenium Biomarkers In Low Income Black And White Americans From The Southeastern United States, Margaret K. Hargreaves, Jianguo Liu, Maciej S. Buchowski, Kushal A. Patel, Celia O. Larson, David G. Schlundt, Donna M. Kenerson, Kristina E. Hill, Raymond F. Burk, William J. Blot

Public Health, Health Administration, and Health Sciences Faculty Research

Biomarkers of selenium are necessary for assessing selenium status in humans, since soil variation hinders estimation of selenium intake from foods. In this study, we measured the concentration of plasma selenium, selenoprotein P (SEPP1), and glutathione peroxidase (GPX3) activity and their interindividual differences in 383 low-income blacks and whites selected from a stratified random sample of adults aged 40–79 years, who were participating in a long-term cohort study in the southeastern United States (US). We assessed the utility of these biomarkers to determine differences in selenium status and their association with demographic, socio-economic, dietary, and other indicators. Dietary selenium intake …

Status Of 10 Additional Bird Species Of Conservation Concern In Us Fish & Wildlife Service Region 6, Christopher J. Butler, Jeffrey B. Tibbits, Katrina Hucks

United States Fish and Wildlife Service: Publications

American Bitterns are medium-sized, brown herons which inhabit large wetlands with dense emergent vegetation. Their cryptic coloration allows them to blend in well with dead emergent vegetation, and American Bitterns have a tendency to “freeze” with the bill pointing up if they feel threatened.

They breed from Newfoundland west to British Columbia (generally south of 55 °N latitude) and south to California, northern New Mexico, and northeastern North Carolina. American Bitterns generally winter in areas where the average temperature remains above freezing. Their winter distribution stretches from Maryland (rarely New Jersey) south to Florida, west to California, south through Mexico …

Science Café | Grounded By Gravity, Jan 22, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Inhibition Of Extracellular Hmgb1 Attenuates Hyperoxia-Induced Inflammatory Acute Lung Injury, Maria Entezari, Mohammad Javdan, Daniel J. Antoine, Dympna M.P. Morrow, Ravikumar A. Sitapara, Vivek Patel, Mao Wang, Lokesh Sharma, Samir Gorasiya, Michelle Zur, Wenjun Wu, Jianhua Li, Huan Yang, Charles R. Ashby, Douglas Thomas, Haichao Wang, Lin L. Mantell

Publications and Research

Prolonged exposure to hyperoxia results in acute lung injury (ALI), accompanied by a significant elevation in the levels of proinflammatory cytokines and leukocyte infiltration in the lungs. However, the mechanisms underlying hyperoxia-induced proinflammatory ALI remain to be elucidated. In this study, we investigated the role of the proinflammatory cytokine high mobility group box protein 1 (HMGB1) in hyperoxic inflammatory lung injury, using an adult mouse model. The exposure of C57BL/6 mice to ≥99% O2 (hyperoxia) significantly increased the accumulation of HMGB1 in the bronchoalveolar lavage fluids (BALF) prior to the onset of severe inflammatory lung injury. In the airways of …

Family Planning And Human Trafficking In China, Hanna Tarbert

De/Constructing Social Justice: Past, Present, and Futures

Divisions concerning best policy practices simmer underneath the Chinese Communist Party's (CCP) image as a united body with one major exception: China's Family Planning Policy or the one child per couple policy. Within the CCP, China's 1.3 billion population is accepted, without challenge as a major problem that must be addressed ever since the party took a hardline stance in 1979 to reduce the Chinese people's fertility. An unintended consequence of the population policy is the significantly skewed ratio between male and female children, causing a scarcity of women, which in turn contributes to the continuous decline in the status …

Phylogeny And Conservation Of The Utah Land Snail Oreohelix Peripherica (Gastropoda: Pulmonata: Camaenidae), Ashley Nelson, Dr. Keith A. Crandall

Journal of Undergraduate Research

The land snail Oreohelix consists of 35 species that are distributed throughout the western United States, southwest Canada and northern Mexico. The majority of these species are endemic to the Great Basin and the Rocky Mountains (Bequaert et al., 1973). Pilsbry (1939) made the last taxonomic revision of the Oreohelix snail in Utah. He described seven species: Oreohelix eurekensis, O. haydeni, O. parawanensis, O. peripherica, O. strigosa, O. subrudis, and O. Yavapai. Traditionally, three subspecies have been ascribed to O. peripherica: O. p. wasatchensis, O. p. newcombi and O. p. weberina, which are distributed in Logan and Ogden Ranger Districts …

Emu Today, January 20, 2014, Eastern Michigan University

EMU Today

No abstract provided.

Amanda Chisolm ’16, Unh Communications And Public Affairs

UNH Today Archive

No abstract provided.

The Adaptive Remodeling Of Endothelial Glycocalyx In Response To Fluid Shear Stress, Ye Zeng, John M. Tarbell

Publications and Research

The endothelial glycocalyx is vital for mechanotransduction and endothelial barrier integrity. We previously demonstrated the early changes in glycocalyx organization during the initial 30 min of shear exposure. In the present study, we tested the hypothesis that long-term shear stress induces further remodeling of the glycocalyx resulting in a robust layer, and explored the responses of membrane rafts and the actin cytoskeleton. After exposure to shear stress for 24 h, the glycocalyx components heparan sulfate, chondroitin sulfate, glypican-1 and syndecan-1, were enhanced on the apical surface, with nearly uniform spatial distributions close to baseline levels that differed greatly from the …