Digital Commons Network^™

Inhibition Of Pim And Axl Kinases As Potential Treatments For A Variety Of Hematological Malignancies And Solid Tumors, Kent James Carpenter

Theses and Dissertations

This thesis is divided into three chapters. In each case, the goal is to achieve inhibition of a growth kinase (PIM or AXL) and subsequent arrest of cell growth and induction of apoptosis (in vitro cell culture models) or decrease in tumor volume (in vivo xenograft studies). Chapter one and chapter two discuss inhibition of proviral integration site for Moloneymurine leukemia virus (PIM) kinases. The three PIM kinases, PIM-1, PIM-2, and PIM-3, are a subfamily of serine/threonine kinases that are known to be involved in signaling pathways as downstream effectors of signal transducer and activator of transcription-5 (STAT5) signaling and …

Endangered And Threatened Wildlife And Plants; Determination Of Threatened Species Status For The Georgetown Salamander And Salado Salamander Throughout Their Ranges, National Archives And Records Administration. Office Of The Federal Register

KIP Articles

We, the U.S. Fish and Wildlife Service (Service), determine threatened status for the Georgetown salamander (Eurycea naufragia) and the Salado salamander (Eurycea chisholmensis) under the Endangered Species Act of 1973 (Act), as amended. The effect of this regulation is to conserve the two salamander species and their habitats under the Act. This final rule implements the Federal protections provided by the Act for these species. We are also notifying the public that, in addition to this final listing determination, today we publish a proposed special rule under the Act for the Georgetown salamander.

The Bg News February 24, 2014, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. February 24, 2014. Volume 93-Issue 69.

February 24th 2014, Csusb

Coyote Chronicle (1984-)

No abstract provided.

Exploring Local Adaptation And The Ocean Acidification Seascape - Studies In The California Current Large Marine Ecosystem, G. E. Hofmann, T. G. Evans, M. W. Kelly, J. L. Padilla-Gamiño, C. A. Blanchette, L. Washburn, F. Chan, M. A. Mcmanus, B. A. Menge, B. Gaylord, T. M. Hill, E. Sanford, M. Lavigne, J. M. Rose, L. Kapsenberg, J. M. Dutton

Faculty Publications

The California Current Large Marine Ecosystem (CCLME), a temperate marine region dominated by episodic upwelling, is predicted to experience rapid environmental change in the future due to ocean acidification. The aragonite saturation state within the California Current System is predicted to decrease in the future with near-permanent undersaturation conditions expected by the year 2050. Thus, the CCLME is a critical region to study due to the rapid rate of environmental change that resident organisms will experience and because of the economic and societal value of this coastal region. Recent efforts by a research consortium-the Ocean Margin Ecosystems Group for Acidification …

Copyright, Fair Use, And Education: Your Rights As A Student, Faculty Member, And Researcher, Julia Lovett, Andrée Rathemacher, Angel Ferria

Technical Services Faculty Presentations

Slides, handouts, and classroom examples from a presentation, "Copyright, Fair Use, and Education: Your Rights as a Student, Faculty Member, and Researcher," offered at the University of Rhode Island Libraries on February 24 and February 25, 2014.

"Learn how Fair Use can help you incorporate copyrighted works (written material, images, video, etc.) into your research, teaching, and academic projects. Have questions about Fair Use and Copyright? Please bring them to these interactive sessions!"

Part of the University Libraries' Search Savvy Seminar series.

Daily Eastern News: Feburary 24, 2014, Eastern Illinois University

February

No abstract provided.

Faculty Senate Meeting Agenda And Minutes, February 24, 2014

Faculty Senate Minutes and Agendas

Agenda and minutes from the Wright State University Faculty Senate Meeting held on, February 24, 2014.

The Patriot Talon (Feburary 24, 2014), University Of Texas At Tyler

The Patriot Talon/The Patriot

The official newspaper for the University of Texas at Tyler before it was changed back to the UT Tyler Patriot. Articles in this issue include: This is all she can physically see & still plays better than you; Progress made on purchase; Tennis player continues to lose eyesight because of retinal disease, still competes on the court; Construction to start next month; Waiting in line for the treadmill a problem? University officials debate whether HPC too small for campus; Is your personal information safe with the University?The Power of Identity; We can make equality happen, it just takes a little …

The Collegian (2014-02-24), Cleiri Quezada

UTB/TSC Archives - The Collegian [Newspaper]

Vol. 66, No. 21

Ghosts, Orphans, And Outlaws: History, Family, And The Law In Toni Morrison's Fiction, Jessica Mckee

USF Tampa Graduate Theses and Dissertations

This dissertation explores Toni Morrison's most prevalent motifs: the ghost, the orphan, and the outlaw. Each figure advances a critique of dominant narratives, specifically those that comprise history, family, and the law. In Chapter One, I argue that Morrison's ghost stories contrast two methods of memory, one that is authoritative and another that is imaginative, in order to counter the official renderings of history. Her ghosts signal forgotten aspects of American history and provide access to another storyline--one that lies in the shadows of the novel's principal narrative. This chapter compares the ghosts of Love and Home in order to …

Development And Assessment Of Plant-Based Synthetic Odor Baits For Surveillance And Control Of Malaria Vectors, Vincent O. Nyasembe, David P. Tchouassi, Hillary K. Kirwa, Woodbridge A. Foster, Peter E.A. Teal, Christian Borgemeister, Baldwyn Torto

All Peer-Reviewed Publications

Background: Recent malaria vector control measures have considerably reduced indoor biting mosquito populations. However, reducing the outdoor biting populations remains a challenge because of the unavailability of appropriate lures to achieve this. This study sought to test the efficacy of plant-based synthetic odor baits in trapping outdoor populations of malaria vectors. Methodology and Principal Finding: Three plant-based lures ((E)-linalool oxide [LO], (E)-linalool oxide and (E)-β-ocimene [LO + OC], and a six-component blend comprising ( E)-linalool oxide, (E)-β-ocimene, hexanal, β-pinene, limonene, and ( E)-β-farnesene [Blend C]), were tested alongside an animal/human-based synthetic lure (comprising heptanal, octanal, nonanal, and decanal [Blend F]) …

A Pilot Study Exploring The Use Of Breath Analysis To Differentiate Healthy Cattle From Cattle Experimentally Infected With Mycobacterium Bovis, Christine K. Ellis, Randal S. Stahl, Pauline Nol, W. Ray Waters, Mitchell V. Palmer, Jack C. Rhyan, Kurt C. Vercauteren, Matthew Mccollum, M. D. Salman

United States Department of Agriculture Wildlife Services: Staff Publications

Bovine tuberculosis, caused by Mycobacterium bovis, is a zoonotic disease of international public health importance. Antemortem surveillance is essential for control; however, current surveillance tests are hampered by limitations affecting ease of use or quality of results. There is an emerging interest in human and veterinary medicine in diagnosing disease via identification of volatile organic compounds produced by pathogens and host pathogen interactions. The objective of this pilot study was to explore application of existing human breath collection and analysis methodologies to cattle as a means to identify M. bovis infection through detection of unique volatile organic compouds or changes …

“This Erstwhile Unreadable Text”: Deep Time, Multidisciplinarity And First-Year Writing Faculty Mentoring And Support, Denise K. Comer

Teaching/Writing: The Journal of Writing Teacher Education

Despite the otherwise rich multidisciplinary terrain of writing studies, the strategies most often used with first-year writing teacher teaching mentoring and support tend to remain discordantly anchored to a comparatively narrow version of writing pedagogy. I argue in this article that the geologic concept of deep time offers a way of infusing a multidisciplinary dimension into first-year writing faculty teaching mentoring and support that will enrich the ways faculty and students think, write, and talk about first-year writing. This article discusses deep-time pedagogy, providing specific strategies for infusing multidisciplinary dimensions into first-year writing faculty teaching mentoring and support. Such a …

Medical School Watercooler Newsletter - February 23, 2014, Lindsey Lyle

Watercooler Newsletter

This is the February 23, 2014 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler.

Contents Include:

• USA Neurology to Host Spring Symposium
• USA Medical Student Matches Early in Ophthalmology
• RSVP Today - 2014 Oncology Outlook
• Med School Café - Expert Advice for the Community
• March 6 DSS to Feature Dr. Christine M. Szymanski

Electromagnetically Induced Transport In Water For Geoenvironmental Applications, Arvin Farid, Atena Najafi, Mahsa Azad, Jim Browning, Elisa Barney Smith

Civil Engineering Faculty Publications and Presentations

Air sparging is a popular soil remediation technique that enables the removal of contaminants through diffusing air into soil. The removal process is, however, slow. The goal of this work is to study the effect of electromagnetic (EM) waves —with minimal heat generation— on transport mechanisms such as diffusion, in order to improve airflow or contaminant transport in order to expedite the cleanup process using air sparging or similar technologies. This effect is studied through an experimental setup that examines the diffusion of a nonreactive dye in water under EM waves at a range of frequencies (50-200 MHz). The electric …

Students Bring Back Powerful Memories From El Salvador, Sarah Gardner, Dave Albee

Press Releases

The trip, organized by Campus Ministry in partnership with Christians for Peace in El Salvador (CRISPAZ), opened hearts and minds to the culture, conditions and challenges of the people of El Salvador, who are still feeling the effects of a 12-year civil war. In a word, there was a sense of solidarity among the Dominican students upon return

From Eugenics To Planned Parenthood: How A Black Feminist Can Reconcile A Troubled Past In Order To Accept A Promising Future, Ebony Davenport

De/Constructing Social Justice: Past, Present, and Futures

Science has long debunked genetic differences between races but prior to this knowledge several hundred thousand people believed otherwise. Fueled by Social Darwinism and evolutionary theories the Eugenics Movement emerged. This school of thought turned into a social movement and began as a method of reducing society to its most fit members. This scientific racism employed an insidious agenda to reduce procreation amongst blacks in America. This ethnic cleansing was rather overt except toward the thousands upon thousands of black women being sterilized unbeknownst to them. Key figures of the American Eugenics Movement contributed large amounts of funds to found …

The Roberts-Kennedy Court And Post-Political Democracy, Zephyr Teachout

Schmooze 'tickets'

This Essay explores the ideological underpinnings of the modern Supreme Court’s election law decisions, arguing that the Court does not have a strong commitment to federalism or to unfettered debate or to the mistrustful citizen. Instead, the opinions reveal a complacency about corruption and a narrow view of the role of citizens. The Essay is part of a volume on neoliberalism for Law and Contemporary Problems.

Marketing Archaeology, William H. Krieger

Philosophy Faculty Publications

In the 19th century, ‘scientific archaeologists’ split from their antiquarian colleagues over the role that provenience (context) plays in the value of an artifact. These archaeologists focus on documenting an artifact’s context when they remove it from its original location. Archaeologists then use this contextual information to place these artifacts within a particular larger assemblage, in a particular time and space. Once analyzed, the artifacts found in a site or region can be used to document, to understand, and explain the past. Given the central place of context for archaeological excavation, archaeologists have done everything in their power to combat …

Averting Lemur Extinctions Amid Madagascar's Political Crisis, Christoph Schwitzer, Russell Mittermeier, Steig Johnson, Giuseppe Donati, Mitchell Irwin, Heather Peacock, Jonah Ratsimbazafy, Josia Razafindramanana, Edward E. Louis, Lounes Chikhi, Ian C. Colquhoun, Jennifer Tinsman, Ranier Dolch, Marni Lafleur, Stephen Nash, Erik Patel, Blanchard Randrianambinina, Tove Rasolofoharivelo, Patricia C. Wright

Anthropology Publications

The most threatened mammal group on Earth, Madagascar’s five endemic lemur families (lemurs are found nowhere else), represent more than 20% of the world’s primate species and 30% of family-level diversity. This combination of diversity and uniqueness is unmatched by any other country—remarkable considering that Madagascar is only 1.3 to 2.9% the size of the Neotropics, Africa, or Asia, the other three landmasses where nonhuman primates occur. But lemurs face extinction risks driven by human disturbance of forest habitats. We discuss these challenges and reasons for hope in light of site-specific, local actions proposed in an emergency conservation action plan.

The Poor Man’S Nuclear Bomb, Erika Simpson

Political Science Publications

No abstract provided.

The Tiger Vol. 108 Issue 5 2014-02-21, Clemson University

Tiger Newspapers

No abstract provided.

Agenda And Minutes, University Of South Florida St. Petersburg General Education Committee Meeting, February 21, 2014, University Of South Florida St. Petersburg. Faculty Senate. General Education Committee

USF St. Petersburg General Education Committee Meetings

Agenda and minutes from the February 21, 2014, meeting of the General Education Committee of the University of South Florida St. Petersburg's Faculty Senate.

The Bison, February 21, 2014

The Bison Newspapers

No abstract provided.

Board Of Trustees Meeting Minutes 2014-02-21, Bowling Green State University

Board of Trustees Meeting Minutes

The official meeting minutes of Bowling Green State University's Board of Trustees.

The Diversity And Distributions Of The Beetles (Insecta: Coleoptera) Of The Guadeloupe Archipelago (Grande-Terre, Basse-Terre, La Désirade, Marie-Galante, Les Saintes, And Petite-Terre), Lesser Antilles, Stewart B. Peck, Michael C. Thomas, Robert H. Turnbow Jr.

Insecta Mundi

The Guadeloupe Archipelago, the French overseas Département de Guadeloupe, is a geographically associated group of islands and a natural biogeographic unit. The islands have been available for terrestrial colonization since the late Tertiary. From the viewpoint of beetle systematics and biodiversity, this is the most important set of islands of the Lesser Antilles because more species have been described or recorded from Guadeloupe than any other island or group in the Lesser Antilles. We present a summary of the 1338 beetle species recorded in the literature from the archipelago, in 60 families, and 719 genera. The families with the largest …

Texas Salamanders, U.S. Department Of The Interior

KIP Articles

No abstract provided.

Undergraduate Curriculum Committee Meeting Minutes, February 21, 2014, Undergraduate Curriculum Committee

All Faculty Senate 2007-2014 Committee Minutes and Reports

Minutes from the Faculty Senate Undergraduate Curriculum Committee meeting held on February 21, 2014.

Physics Colloquium | Applications Of Squids From Brains To Bombs, Feb 21, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.