Digital Commons Network^™

Ostertagia Ostertagi Macrophage Migration Inhibitory Factor Is Present In All Developmental Stages And May Cross-Regulate Host Functions Through Interaction With The Host Receptor, Guanggang Qu, Raymond Fetterer, Lin Leng, Xin Du, Dante Zarlenga, Zhiqiang Shen, Wenyu Han, Richard Bucala, Wenbin Tuo

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Macrophage migration inhibitory factor (MIF) of Ostertagia ostertagi, an abomasal parasite of cattle, was characterised in the present study. Phylogenetic analysis identified at least three O. ostertagi MIFs (Oos- MIFs), each encoded by a distinct transcript: Oos-MIF-1.1, Oos-MIF-1.2 and Oos-MIF-2. Oos-MIF-2 is only distantly related to Oos-MIF-1s, but has higher sequence similarity with the Caenorhabditis elegans MIF2. Oos-MIF-1.1 and Oos-MIF-1.2 are similar (93%) and thus collectively referred to as Oos-MIF-1 when characterised with immunoassays. Recombinant Oos-MIF-1.1 (rOos-MIF-1.1) is catalytically active as a tautomerase. A mutation (rOos-MIF-1.1P1G) or duplication of Pro1 residue (rOos-MIF-1.1P1+P) resulted in reduced oligomerisation and loss of tautomerase …

The Molecular Biology And Treatment Of Malignant Melanoma With Brafv600 Mutations, Michael P. Mullane

Journal of Patient-Centered Research and Reviews

Since 2011, the treatment options for metastatic malignant melanoma have significantly changed. In that year, ipilimumab, an anti-CTLA4 monoclonal antibody, and vemurafenib, a potent inhibitor of mutated-BRAF (V600E and V600K), were approved by the U.S. Food and Drug Administration (FDA). In 2013, dabrafenib, another inhibitor of mutated-BRAF, and trametinib, a MEK inhibitor, were approved by the FDA. Most recently, combination therapy with dabrafenib and trametinib was approved. This article will describe a patient with metastatic malignant melanoma with BRAF^V600E who has responded very well to vemurafenib monotherapy. We will then explore the molecular basis, pharmacologic development and clinical outcomes …

Trans-Substantivity And The Processes Of American Law, David Marcus

BYU Law Review

The term “trans-substantive” refers to doctrine that, in form and manner of application, does not vary from one substantive context to the next. Trans-substantivity has long influenced the design of the law of civil procedure, and whether the principle should continue to do so has prompted a lot of debate among scholars. But this focus on civil procedure is too narrow. Doctrines that regulate all the processes of American law, from civil litigation to public administration, often hew to a trans-substantive norm. This Article draws upon administrative law, the doctrine of statutory interpretation, and the law of civil procedure to …

Is The Clean Water Act's Diligent Prosecution Bar Jurisdictional? A Journey Into Discovering Congressional Intent, Szonja Ludvig

BYU Law Review

No abstract provided.

Volume Cxxxi, Number 16, February 28, 2014, Lawrence University

The Lawrentian

No abstract provided.

Determinan Kejadian Malaria Di Wilayah Endemis, Hamzah Hasyim, Anita Camelia, Nur Alam Fajar

Kesmas

Kabupaten Lahat adalah salah satu wilayah endemis malaria di Sumatera Selatan dengan prevalensi 16,4% dan Annual Malaria Incidence 22,08. Tujuan penelitian ini untuk mengetahui faktor risiko lingkungan dengan kejadian malaria. Faktor risiko lingkungan genangan air (breeding place) berhubungan dengan kejadian malaria dengan nilai p= 0,000. Analisis multivariat menemukan determinan utama kejadian malaria adalah breeding place di sekitar rumah responden dengan odds ratio (OR) = 5,034 dan 95% CI = 2,65 _ 9,56. Responden yang tinggal di sekitar breeding place berisiko 5,03 kali lebih besar untuk menderita malaria dibandingkan dengan responden yang di sekitar rumah tidak terdapat breeding place setelah dikontrol …

Komorbiditas Pecandu Narkotika, Rico Januar Sitorus

Kesmas

Narkotika yang disalahgunakan dapat menimbulkan ketergantungan. Semakin lama mengalami ketergantungan narkotika akan semakin memperburuk kualitas kesehatan. Pada pengguna narkoba suntik, komplikasi komorbiditas seperti hepatitis, tuberkulosis paru, dan HIV/AIDs juga semakin tinggi. Tujuan penelitian ini adalah mengetahui komorbiditas pada penyalah guna narkoba dan determinannya. Metode penelitian adalah potong lintang dengan menggunakan data sekunder catatan medis (medicalrecord) di Rumah Sakit Ketergantungan Obat (RSKO) Jakarta tahun 2013. Populasi dalam penelitian ini adalah seluruh pasien ketergantungan narkoba yang dirawat inap, yang menjalani rehabilitasi dan rawat jalan, dan sampel penelitian ini adalah seluruh populasi sebesar 303 orang. Analisis data yang digunakan adalah analisis secara univariat, …

Aktivitas Fisik, Stres, Dan Obesitas Pada Pegawai Negeri Sipil, Winne Widiantini, Zarfiel Tafal

Kesmas

Pada tahun 2008, sekitar 2,8 juta orang dewasa meninggal akibat obesitas, sekitar 300 juta orang yang secara klinis tergolong obesitas yang merupakan penyokong utama penyakit degeneratif seperti diabetes, penyakit jantung, dan kanker. Penelitian ini bertujuan mengetahui prevalensi obesitas pada Pegawai Negeri Sipil (PNS) Sekretariat Jenderal Kementerian Kesehatan Republik Indonesia dan pengaruh aktivitas fisik dan stres terhadap obesitas. Penelitian potong lintang ini dilakukan pada bulan Mei - Juni 2013 di Jakarta pada 230 responden yang dipilih secara acak sistematik dari 1.119 PNS. Obesitas diukur dengan Indeks Massa Tubuh (IMT) berupa rasio berat badan (kilogram) dibagi tinggi badan kuadrat (meter2), responden dinyatakan …

Ocean Acidification Impairs Vermetid Reef Recruitment., Marco Milazzo, Riccardo Rodolfo-Metalpa, Vera Bin San Chan, Maoz Fine, Cinzia Alessi, Vengatesen Thiyagarajan, Jason M. Hall-Spencer, Renato Chemello

School of Biological and Marine Sciences

Vermetids form reefs in sub-tropical and warm-temperate waters that protect coasts from erosion, regulate sediment transport and accumulation, serve as carbon sinks and provide habitat for other species. The gastropods that form these reefs brood encapsulated larvae; they are threatened by rapid environmental changes since their ability to disperse is very limited. We used transplant experiments along a natural CO2 gradient to assess ocean acidification effects on the reef-building gastropod Dendropoma petraeum. We found that although D. petraeum were able to reproduce and brood at elevated levels of CO2, recruitment success was adversely affected. Long-term exposure to acidified conditions predicted …

An Updated And Annotated Checklist Of The Larger Butterflies (Papilionoidea) Of Trinidad, West Indies: Papilionidae, Pieridae And Nymphalidae, Matthew J. W. Cock

Insecta Mundi

A revised checklist for the butterfly families Papilionidae, Pieridae and Nymphalidae of Trinidad (Trinidad and Tobago) is presented, bringing nomenclature in line with modern usage, indicating synonyms from earlier lists and adding new records since the last checklist was published in 1970. Migrant and vagrant species are provisionally recognised, and records considered incorrect are discussed. The checklist includes 204 species: 15 Papilionidae, 29 Pieridae and 160 Nymphalidae. The only taxonomic change is to treat Hamadryas feronia insularis (Fruhstorfer) as a synonym of H. f. feronia (Linnaeus), syn. nov., and not as a synonym of H. feronia farinulenta (Fruhstorfer).

Adiponectin Inhibits Tumor Necrosis Factor-Α-Induced Vascular Inflammatory Response Via Caveolin-Mediated Ceramidase Recruitment And Activation., Yajing Wang, Xiaoliang Wang, Wayne Bond Lau, Yuexing Yuan, David Booth, Jing-Jing Li, Rosario Scalia, Kyle Preston, Erhe Gao, Walter Koch, Xin-Liang Ma

Department of Medicine Faculty Papers

RATIONALE: Anti-inflammatory and vascular protective actions of adiponectin are well recognized. However, many fundamental questions remain unanswered.

OBJECTIVE: The current study attempted to identify the adiponectin receptor subtype responsible for adiponectin's vascular protective action and investigate the role of ceramidase activation in adiponectin anti-inflammatory signaling.

METHODS AND RESULTS: Adiponectin significantly reduced tumor necrosis factor (TNF)α-induced intercellular adhesion molecule-1 expression and attenuated TNFα-induced oxidative/nitrative stress in human umbilical vein endothelial cells. These anti-inflammatory actions were virtually abolished by adiponectin receptor 1 (AdipoR1-), but not AdipoR2-, knockdown (KD). Treatment with adiponectin significantly increased neutral ceramidase (nCDase) activity (3.7-fold; P87% of adiponectin-induced nCDase …

Experience Of Internet Utilization By Post Graduate Students At Nishter Medical College, Multan, Pakistan, Rubina Bhatti, Muhammad Waqas Javed

Library Philosophy and Practice (e-journal)

This study reports the Internet usage, purposes, difficulties while using internet by the Post Graduate Sstudnets at Nishtar Medical College (NMC), Multan and also identifies the usage of different health related websites and databases to supplement learning by PGS. This study is based on comprehensive literature review and pre-tested questionnaire that was distributed among 210 PGS. The response rate was very satisfactory 85%. The collected data was finally analyzed by using SPSS version 17. The results show that 33(18.5%) were female and 145(81.5%) male in total 178 respondents. All of the respondents used internet except only one respondent. Majority of …

Closing Remarks And Vote Of Thanks, Saima Sachwani

AKU Symposium

No abstract provided.

Relationship Of Socio-Demographic Factors With Serum Levels Of Vitamin D In A Pakistani Population Of Diabetic Patients And Healthy Controls, Khalida Iqbal

AKU Symposium

No abstract provided.

Media And Ncds: The Role Of Media In Health Reform Advocacy, Ms Huma Baqai

AKU Symposium

No abstract provided.

Research Growth And Development At Sambalpur University During 2008-2012: A Bibliometric Analysis, Rabindra K. Maharana

Library Philosophy and Practice (e-journal)

Sambalpur Univesity (SU) was started functioning from 1st January, 1967 in the Odisha State. The university imparting study and research through 27 post-graduate departments in disciplines of Science, Humanities, Business Administration, Social Sciences, Law and Commerce. The present study aims to study the research performance of SU’s publications that have been indexed in Scopus during 2008 to 2012. The study also identifies the annual growth of university publication, authorship pattern, author productivity, degree of collaboration, length of paper published, most prolific contributor, prolific institution/ organization, geographical distribution etc. Lotka’s law of scientific productivity was used to determine the author’s productivity …

Information Literacy Skills Of Faculty Members: A Study Of The University Of Lahore, Pakistan, Ghulam Murtaza Rafique

Library Philosophy and Practice (e-journal)

Purpose – The objective of this study is to gauge the level of information literacy skills of faculty members of the University of Lahore.

Design/methodology/approach – To collect required data from population, survey method was used. The participants consisted of the faculty members currently working in the University of Lahore, which reflected the conditions and environment of all campuses of the University of Lahore. A simple random sampling technique was used to select the sample from population of 650 faculty members of the university. The sample size consisted of 84 faculty members in randomly selection. A questionnaire was formulated and …

Research Output Of Some Selected Indian Medical Research Institutions (2007-2011), Ramesh Pandita, Shivendra Singh Mr., Ramesh C. Gaur Dr.

Library Philosophy and Practice (e-journal)

Research is the backbone of any subject field, not just required to be undertaken for its survival and sustenance but also for the furtherance of subject scope. Most of the research activities undertaken at any level are aimed towards the welfare and betterment of living being and humans being the first consideration. Medical research has always been the supreme fantasy of humans as it has got direct bearing upon human health and longevity of life. In the present study attempt has been made to have an analysis of medical literature produced in four most primer medical and research institutions of …

Ncds: Behaviour Change Communication And Advocacy Strategies, Dr Nabeela Ali

AKU Symposium

No abstract provided.

Role Of Health Care Providers In Preventing Obesity, Dr Abdul Jabbar

AKU Symposium

No abstract provided.

The Fierce Green Fire: Vol. 4 Issue 14, Wofford College Environmental Studies Program

The Fierce Green Fire

No abstract provided.

Sr-13-14-66 Apc, Marshall University

Recommendations

No abstract provided.

Sr-13-14-62 Apc, Marshall University

Recommendations

No abstract provided.

College Senate Minutes February 27, 2014, Bronx Community College Senate

BCC Governance Archives

Minutes for the meeting of the College Senate on February 27, 2014.

Vol.41 N.31 February 27th 2014, Brown Publishing Company

Black Voice News

No abstract provided.

The Setonian, February 27, 2014, Seton Hall University

2014

No abstract provided.

Chanticleer | February 27, 2014, Jacksonville State University

Chanticleer

No abstract provided.

Ua12/2/1 College Heights Herald, Vol. 89, No. 37, Wku Student Affairs

WKU Administration Documents

WKU campus newspaper reporting campus, athletic and Bowling Green, Kentucky news.

• Downey, Casey. Sexual Assault Awareness Month Sheds Light on Important Issue
• Brown, Leah. Student Government Association Releases Budget Report
• Mudd, Aaron. Outdoor Recreation Activity Center Helps Students Explore Outdoors
• Brown, Leah. Sigma Chi Aims to Beat Cancer with Annual Fight Night
• Lawson, Anna. Bonner Scholars Provide Books for Youth
• Corum, John. Women Recognized for Their Contributions to Campus
• And the Winner Is . . . – Academy Awards, Entertainment
• Botsford, Jabin. Turn Down for What? – Concerts, Entertainment
• Burton, Kristina. WKU FeelGood Works to End World Hunger
• Burton, Kristina. …

February 27, 2014, James Madison University

The Breeze, 2010-2019

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

Ecolunch | Keeping A Cool Head The Evolution Of Thermoregulatory Cranial Vasculature In Ungulates, March 12, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.