Digital Commons Network^™

Early-Onset Metabolic Syndrome In Mice Lacking The Intestinal Uric Acid Transporter Slc2a9, Brian J. Debosch, Oliver Kluth, Hideji Fujiwara, Annette Schürmann, Kelle Moley

Open Access Publications

No abstract provided.

Dumping The “Anti-Dumping” Law: Why Emtala Is (Largely) Unconstitutional And Why It Matters, E. H. Morreim

Minnesota Journal of Law, Science & Technology

No abstract provided.

Whole-Genome Sequencing Of Salmonella Enterica Subsp. Enterica Serovar Cubana Strains Isolated From Agricultural Sources, George Weinstock, Et Al

Open Access Publications

No abstract provided.

Age, Gender, And Cancer But Not Neurodegenerative And Cardiovascular Diseases Strongly Modulate Systemic Effect Of The Apolipoprotein E4 Allele On Lifespan, Alexander M. Kulminski, Konstantin G. Arbeev, Irina Culminskaya, Liubov Arbeeva, Svetlana V. Ukraintseva, Eric Stallard, Kaare Christensen, Nicole Schupf, Michael A. Province, Anatoli I. Yashin

Open Access Publications

No abstract provided.

Designing Vaccines To Neutralize Effective Toxin Delivery By Enterotoxigenic Escherichia Coli, James M. Fleckenstein, Alaullah Sheikh

Open Access Publications

No abstract provided.

Cns Amyloid-Β, Soluble App-Α And-Β Kinetics During Bace Inhibition, Justyna A. Dobrowolska, Bruce W. Patterson, Robert Chott, Vitality Ovod, Yuriy Pyatkivskyy, Kristin R. Wildsmith, Tom Kasten, Kevin E. Yarasheski, Randall J. Bateman, Et Al

Open Access Publications

No abstract provided.

Heterogeneous Immunological Landscapes And Medieval Plague : An Invitation To A New Dialogue Between Historians And Immunologists., Fabian Crespo, Matthew B. Lawrenz

Faculty and Staff Scholarship

Efforts to understand the differential mortality caused by plague must account for many factors, including human immune responses. In this essay we are particularly interested in those people who were exposed to the Yersinia pestis pathogen during the Black Death, but who had differing fates—survival or death—that could depend on which individuals (once infected) were able to mount an appropriate immune response as a result of biological, environmental, and social factors. The proposed model suggests that historians of the medieval world could make a significant contribution to the study of human health, and especially the role of human immunology in …

Transcriptional Regulation Of Neurogenic Atrophy-Induced Gene Expression By Muscle Ring Finger-1 And Myogenic Regulatory Factors, Theodore Olson

UNF Graduate Theses and Dissertations

Skeletal muscle wasting is a consequence of numerous physiological conditions, including denervation, corticosteroid treatment, immobilization, and aging. The E3 ubiquitin ligases, MuRF1 and MAFbx, are induced under nearly all atrophy conditions and are believed to play a key role in protein degradation in atrophying muscle. However, the preliminary data described in this study provides new evidence that MuRF1 may also act as a transcriptional modulator of atrophy-induced gene activity, including the regulation of MAFbx and MuRF1 expression. To characterize the transcriptional regulation of MuRF1 and MAFbx, reporter gene constructs containing fragments of the proximal promoter regions of these genes were …

Food For Thought And Thought For Food: Applying Care Ethics To The American Eater, Catherine Manners Bucolo

UNF Graduate Theses and Dissertations

This piece provides an application of care ethics to the typical American diet. In the first chapter, the problems surrounding the Standard American Diet are discussed at both the individual, familial, global, animal, and environmental levels. The second chapter provides an overview of the theoretical components of care ethics, and lays a framework for analysis. The third and final chapter demonstrates how in applying many of the core principles of care, great strides can be made in remedying the numerous problems that are a direct result of typical consumption habits in the United States.

Midline Catheter Use In The Newborn Intensive Care Unit, Tricia L. Romesberg

UNF Graduate Theses and Dissertations

Ongoing evaluation of current practice and incorporation of evidence based research into guidelines and protocols is a requirement for the provision of high quality, cost efficient care. Despite some literature describing observational data, midline catheters (MCs) are not an appropriate vascular access device for Newborn Intensive Care Unit (NICU) patients due to insufficient high level evidence demonstrating safety and efficacy. In addition, national guidelines for MC use in neonatal and infant patients lacks sufficient information for safe and effective use of MCs.

The results of this small, online survey indicate that while some neonatal nurses and Nurse Practitioners report the …

Increasing Physical Activity In Post Liver Transplant Patients, Jennifer Lynn Serotta

UNF Graduate Theses and Dissertations

The purpose of this quality improvement project was to increase physical activity among postoperative adult liver transplant patients, improve documentation of daily activity, and ultimately influence quality of life (QOL). Quality of life has been shown to improve dramatically after liver transplant, as patients enter transplant severely debilitated with limitations on their physical activity which carry over following transplant. The literature supports that liver transplant patients should engage in physical activity which may improve QOL. Thirteen liver transplant patients were recruited within the seven days of their post-operative hospitalization. Twelve patients consented, were educated about the benefits of walking, given …

Behavioral Feeding Interventions For Pediatrics, Morgan L. Feltmeier

Research Papers

No abstract provided.

Effects Of Osteoarthritis And Chronic Pain Management For Companion Animals, Rebecca A. Cason

Research Papers

No abstract provided.

Promoting A Shared Vision: Identifying Intersections Between Food And Fiber Systems Literacy Benchmarks And Illinois State Board Of Education Standards, Daniel P. Ingold Mr.

Research Papers

Understanding of agricultural systems has been an accepted and necessary aspect of a child’s education for centuries. Conventional agricultural education has proven effective in creating well-trained agricultural professionals and scholars, but has had the unintentional effect of limiting access to agricultural concepts to the non-agricultural student. This effect has potentially negative cultural consequences considering the importance agricultural issues. In response, agricultural educators have carried out an initiative to promote agricultural literacy in the classroom through an integration of agricultural concepts into core curriculum. A Guide to Food and Fiber Systems Literacy Benchmarks (Leising, 1998) is an example of programs that …

State Responsibility For Gender Stereotyping, Barbara Stark

Hofstra Law Faculty Scholarship

Scholars have recently re-discovered Justice Ruth Bader Ginburg’s early anti-stereotyping work. As Cary Franklin notes, Justice Ginsburg’s approach "was grounded not in a commitment to eradicating sex classifications from the law, but in a far richer theory of equal protection involving constitutional limitations on the state’s power to enforce sex-role stereotypes." Some of these scholars believe that this approach holds great promise for issues at the "frontiers of equal protection law" such as same-sex marriage and the work-family conflict. As Ginsburg herself has come to realize, however, anti-stereotyping is only the beginning. This Article explains why anti-stereotyping is insufficient, what …

The Conceptual Framework And Assessment Methodology For The Systematic Reviews Of Community-Based Interventions For The Prevention And Control Of Infectious Diseases Of Poverty, Zohra S. Lassi, Rehana A. Salam, Jai K. Das, Zulfiqar A. Bhutta

Department of Paediatrics and Child Health

This paper describes the conceptual framework and the methodology used to guide the systematic reviews of community-based interventions (CBIs) for the prevention and control of infectious diseases of poverty (IDoP). We adapted the conceptual framework from the 3ie work on the 'Community-Based Intervention Packages for Preventing Maternal Morbidity and Mortality and Improving Neonatal Outcomes' to aid in the analyzing of the existing CBIs for IDoP. The conceptual framework revolves around objectives, inputs, processes, outputs, outcomes, and impacts showing the theoretical linkages between the delivery of the interventions targeting these diseases through various community delivery platforms and the consequent health impacts. …

Gender Differences In High Sensitivity C - Reactive Protein And Self-Reported Muscle Strengthening Activity Among U.S. Adults, Michael R. Richardson

UNF Graduate Theses and Dissertations

Objectives: We sought to examine the gender differences between C - reactive protein (CRP) and muscle strengthening activity (MSA) in U.S. adults (≥20 years of age)

Background: Elevated levels of CRP have been shown to be associated with an increase in risk of cardiovascular disease (CVD). Studies analyzing the relationship between physical activity (PA) and CRP by gender have produced mixed results.

Methods: The sample (n=9,135) included participants in the 1999-2004 National Health and Nutrition Examination Survey (NHANES). Three categories of reported MSA participation were created: no MSA (referent group), some MSA (≥1 to/wk), and meeting the …

Formaldehyde Exposure In Pregnant Women And Its Relationship To Fetal Growth, Azita Amiri

All ETDs from UAB

Formaldehyde exposure during pregnancy has been linked to adverse pregnancy outcomes such as poor fetal growth, although few studies have examined formaldehyde exposure during pregnancy and its relationship to fetal growth. The purpose of this study was to determine the level of formaldehyde exposure during pregnancy and examine the relationship between formaldehyde exposure and fetal growth. Formaldehyde exposure was examined, using vapor monitor badge and urine formic acid, in 140 women in their second trimester of pregnancy. One time urine samples were collected during a routine prenatal visit, and women wore the vapor badges for 24 hours. Fetal growth was …

Fatigue Testing Of Straight And Angled Abutments In A High Torque Dental Implant System, Rana M. Atieh

All ETDs from UAB

Root form dental implants are a common solution used today to replace missing teeth. However current designs still suffer from a number of limitations. Angled abutments are used for incisors, where maximum human bite forces are normally < 200N, while straight abutments are used for molars subjected to higher forces > 200 N. The aim of this study was to evaluate the mechanical performance of a novel dental implant system by fatigue testing straight and 15-degree angled abutments. It was hypothesized that the novel thread design will dissipate the load evenly throughout the implant allowing the system to withstand normal chewing forces. Implants with 4.2mm diameter were tested according to ISO 14801 in specimen …

Moocs And Legal Education: Valuable Innovation Or Looming Disaster?, Philip G. Schrag

Villanova Law Review (1956 - )

No abstract provided.

Short-Term Safety And Efficacy Of Fish-Oil Emulsions On The Prevention Of Parenteral Nutrition-Associated Liver Disease In Surgical Neonates: A Randomized Controlled Trial, Jrarat Ariyawangso, Chankit Puttilerpong, Suntaree Ratanachu-Ek, Maitree Anuntkosol

The Thai Journal of Pharmaceutical Sciences

Surgical neonates requiring prolonged parenteral nutrition (PN) are at risk for parenteral nutrition-associated liver disease (PNALD) that contributes to an increase in morbidity and mortality in surgical infants. Current lipid emulsions used with neonat...

Baseline Measures Associated With Subsequent Weight Loss In Overweight Girls, Alexandra French

All ETDs from UAB

Purpose: To evaluate the relationships among baseline weight, resting energy expenditure (REE), and aerobic fitness (AF) with subsequent weight loss in pre-pubertal overweight girls (7-11) undergoing a dietary weight-loss program. Methods: Using data from a prior study (PRIMO Study, PI Krista Casazza, PhD, RD at UAB) baseline measures of baseline weight, REE, and AF of 22 participants were analyzed using SPSS statistical program. The purpose of the PRIMO Study was to compare two diets differing in carbohydrate and fat content in improving metabolic outcomes, and to achieve weight loss in overweight pre-pubertal girls aged 7-11. The inclusion criteria for the …

Three Studies On Family Meals: Examining The Predictors Of Family Meals And Its Impact On Adolescent Health, Samantha Sittig Goldfarb

All ETDs from UAB

This three-manuscript dissertation addresses gaps in the literature related to the predictors of family meals and its impact on adolescent health behavior. Sharing dinner as a family has been promoted by the media and many researchers as an ideal environment to enrich the parent-child bond and subsequently reduce adolescent risk behaviors such as substance use and delinquency. This dissertation centers on three topics, in particular: (1) the nature of the family meal literature given the multiple adolescent health behavior outcomes, study designs, and model types investigated and used by researchers, (2) the impact of family dinners on adolescent school problems, …

Acculturation And Social Support As Predictors Of Physical Activity In A Web-Based Intervention For Latinas, Tanya Benitez

All ETDs from UAB

Latinas in the United States report high levels of physical inactivity and are disproportionately burdened by associated chronic diseases, demonstrating the need for innovative approaches to reducing these disparities. The purpose of the current study was to evaluate self-reported changes in physical activity and social support, and to examine the association between physical activity and acculturation, following a one month culturally and linguistically adapted, theory-driven (Social Cognitive Theory and Transtheoretical Model) Internet-based physical activity intervention for Latina adults. Data was collected from Spanish-speaking Latinas (N=24) between the ages of 21-61 years (M=35.17, SD=11.22) enrolled in a web-based physical activity pilot …

A Systematic Evaluation Of An Educational Bible Study Classes Focusing On Diabetes Prevention - Just Having C.H.U.R.C.H: Controlling How Unhealthy Regimens Can Hurt., Latoya Rena Bishop

All ETDs from UAB

Diabetes is a growing problem in public health and the African-American population. Preventive measures such as changes in diet, increasing physical activity, and weight control are behaviors that will lead to a healthier lifestyle and prevent the onset of diabetes. The purpose of this study was to determine if the National Diabetes Education Program Power to Prevent curriculum improved diabetes prevention perceptions and behaviors among participants receiving the curriculum. The study tested the effectiveness of Power to Prevent specifically designed for African-Americans, paired with scripture in a bible school format, for diabetes prevention in local Baptist churches in Birmingham, AL. …

The Role Of The Developing Microbiome In Mucosal Defense Of The Neonatal Gut, Emily G. Blosser

All ETDs from UAB

Neonatal late-onset sepsis is invasive infection occurring after the first 48 hours of life, and one of the leading causes of death among preterm infants in the United States and abroad. Infections with Gram-negative bacteria, such as Klebsiella pneumonia, occurring when bacteria translocate across premature gut epithelium into the bloodstream, can be particularly severe. Preterm infants in the neonatal intensive care unit undergo intense antibiotic regimens due to high risk of infection. Paradoxically, prolonged exposure of preterm infants to empiric antibiotic therapy early in the hospital stay is associated with increased risk of intestinal infection and death after adjustment for …

Glycine Supplementation To Improve Insulin Sensitivity In Humans, Marie-Hippolyte Boni Epse Attobla

All ETDs from UAB

The main purpose of this pilot study was to investigate the insulin sensitizing effect of glycine as a dietary supplement in insulin resistant (IR) normoglycemic subjects (N= 10), and to determine significant changes in insulin sensitivity and lipid profile after four weeks of glycine supplementation. Descriptive statistics were used to describe the basic characteristics of the study population. A paired t-test was used to determine differences between insulin sensitivity and lipid profile pre- and post- intervention, considering the estimation of HOMA-IR and Matsuda- index scores. Results showed that glycine supplementation might improve triglyceride (TG) levels in European Americans; and low-density …

Exposure To Methylmercury Via Fish Consumption In Ghana And An Evaluation Of Methylmercury Toxicity Under A Low Food Ration In Daphnia Pulex, Dzigbodi Adzo Doke

All ETDs from UAB

For many people of the world, fish is a primary source of protein, especially in countries like Ghana, where about 60% of the protein consumed is derived from fish. Fish advisories have been established by some nations to protect the public from harmful health effects linked to eating contaminated fish. Methylmercury (MeHg) is one such contaminant that has resulted in fish advisories. Fish advisories have not been developed in Ghana, although MeHg contamination of aquatic ecosystems is likely due to the long history of mercury (Hg) use in artisanal gold mining. To address this gap in our knowledge, I compiled …

Association Of Blood Pressure Phenotypes With Kidney Disease, Rikki M. Tanner

All ETDs from UAB

model. The sex ratios produced in the fluctuating temperature experiments were not

Employer-Based Wellness Programs; Financial Value To The Organization, Ricky D. Wallace

All ETDs from UAB

The health and wellness of employees is of strategic importance for healthcare organizations to achieve leadership in accountable care and health reform. This study sought to discover whether an organizational program, focused on health promotion and wellness for employees, has a value to the organization. This quantitative evaluation study examines variables of a wellness program implemented at a medical facility in the United States by determining the medical costs among participants and non-participants of the facility sponsored wellness program. The results of the study provide valuation evidence concerning the program's value to the organization.