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Journal Of Food Law & Policy - Spring 2014, Journal Editors

Journal of Food Law & Policy

No abstract provided.

Preventive Effect Of Non-Mitogenic Acidic Fibroblast Growth Factor On Diabetes-Induced Testicular Cell Death., Melissa Skibba 1990-

Electronic Theses and Dissertations

Fibroblast growth factor (FGF)-1 was found to protect the heart from oxidative damage, but clinically its long-term use was restricted for its undesirable proliferating activity on cells. Thus a cluster of amino acids responsible for the proliferation were deleted in the native FGF-1 to create a non-mitogenic FGF-1 (nmFGF-1). To assess whether nmFGF-1 protects male germ cells from diabetes-induced apoptotic death, the study employed a murine model of diabetes using multiple low-doses of streptozotocin, followed by nmFGF-1 treatment for 6 months. Diabetic mice showed a decrease in testicular weight and an increase in apoptotic cell death. Treatment with nmFGF-1 alleviated …

Inflammation-Resolving Lipid Mediators Promote Revascularization To Enhance Wound Healing., Michael Jingyuan Zhang

Electronic Theses and Dissertations

Wound healing is a highly concerted cellular process that begins with inflammation and proceeds to resolution to revascularize the site of injury. Although inflammation is essential to revascularization during wound healing, it is now recognized that resolution is an active process that is equally important. Other investigations have implicated a beneficial effect of resolving inflammation and promoting resolution in the remission of inflammatory pathologies. Recently investigations have yielded a novel class of ?-3 fatty acid derived lipid mediators, biosynthesized by leukocytes, which are capable of resolving inflammation and promoting resolution. We therefore hypothesized that these leukocyte-derived pro-resolving lipid mediators can …

Epigenetic Modifications Associated With Aortic Remodeling In Hyperhomocysteinemia., Nithya Narayanan

Electronic Theses and Dissertations

Background: Hyperhomocysteinemia (HHcy) is prevalent in hypertensive patients and is an independent risk factor for aortic pathologies. HHcy is known to cause an imbalance between matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) leading to accumulation of collagen in the aorta resulting in stiffness and development of hypertension. Although the exact mechanism of extracellular matrix remodeling (ECM) is unclear, emerging evidence implicates epigenetic regulation involving DNA methylation. The purpose of the study was to investigate whether inhibition of DNA methylation reduces high blood pressure by regulating aortic ECM remodeling in HHcy. Methods: In the first set of experiments, we …

Markers And Mechanisms Of Metabolic Aging., Peter Dziewornu Ahiawodzi

Electronic Theses and Dissertations

Oxidative stress has been implicated in aging and age-related diseases. Using three distinct studies, this dissertation examines associations between lifestyle factors and oxidative stress, and their effects on advanced glycation end products, telomere length, and type II diabetes. Carboxymethyl-lysine (CML), an advanced glycation end-product, has been linked to oxidative stress, cardiovascular and other age-related diseases. The first study investigates the association between sleep disordered breathing (SDB), a source of oxidative stress, and CML. 1002 participants with sleep data from the Cardiovascular Health Study (CHS) were analyzed. SDB was not significantly associated with CML, but after stratification by gender and hemoglobin …

The Role Of Pesticides In Non-Alcoholic Fatty Liver Disease (Nafld)., Laila Al-Eryani 1986-

Electronic Theses and Dissertations

NAFLD, the most common form of liver disease worldwide, is caused by various factors including industrial chemicals and pesticides exposure. Annually, 5.2 billion pounds of pesticides are used worldwide and can contribute to liver disease, but their role is modestly studied. We hypothesize that pesticides contaminating food supply can worsen diet-induced steatosis via xenobiotic receptor activation. Two human and two rodent databases were utilized and 85% of the 330 chemicals identified associated with NAFLD were pesticides. Eight were selected for evaluating hepatic receptor activation in vitro. The majority including DDT activated hPXR/CAR and mPXR. DDT (100 mg/kg) was studied in …

Neutrophils Alter Epithelial Response To Porphyromonas Gingivalis In A Gingival Crevice Model., Jessica Lynn Bondy-Carey 1987-

Electronic Theses and Dissertations

A gingival crevice model (epithelial cell-Porphyromonas gingivalis-neutrophil) was established and used to profile gingipain, matrix metalloproteinase (MMP), MMP mediators [neutrophil gelatinase-associated lipocalin (NGAL) and tissue inhibitor of metalloproteinases 1 (TIMP-1)] and cytokine networks. Smoking is the primary environmental risk factor for periodontitis. Therefore, the influence of cigarette smoke extract (CSE) was also monitored in the same model. Porphyromonas gingivalis alone induced low levels of interleukin-1b and interleukin-8 from epithelial cells, but high levels of both cytokines were produced on the addition of neutrophils. Exposure to CSE (100 and 1000 ng mL1 nicotine equivalency) significantly compromised P. gingivalis-induced cytokine secretion (both …

Effectiveness Of Chronic Obstructive Pulmonary Disease (Copd) Management Program At The University Of Louisville., Malhar Anantbhai Jhaveri

Electronic Theses and Dissertations

Background: Chronic obstructive pulmonary disease (COPD) is a progressive disease of the respiratory system characterized by airflow limitation that is not completely reversible and is associated with systemic effects especially of the cardiovascular system. COPD is frequently complicated by acute exacerbations that contribute to physical impairment and increased health care use. As COPD is a chronic lung disease with significant systemic manifestations, it is important to have chronic disease management programs specifically targeting individuals with COPD designed to improve their overall quality of life, reduce the burden of disease and decrease the impact of COPD on daily life. Chronic disease …

Effects Of Distillers Grains Plus Solubles And Monensin Supplementation On Yearlings Grazing Smooth Bromegrass, Tyler L. Hasenauer

Department of Animal Science: Dissertations, Theses, and Student Research

Supplementing cattle on grass is an effective way of increasing animal efficiency and grass utilization. Distiller grains plus solubles (DGS) supplementation has been repeatedly proven as an effective supplement by providing ruminally undegradable protein (RUP), fat, and highly digestible fiber. The effects of monensin supplementation on grazing cattle are variable. Although some research has shown a decrease in forage organic matter intake (FOMI), the popular belief is monensin increases ADG while maintaining DMI in a grazing situation. Two experiments were designed to observe the effects of DGS and monensin supplementation on cattle grazing smooth bromegrass. In the first study, ADG …

Genomic Predictions For Age At Puberty And Reproductive Longevity In Sows Using Bayesian Methods, Katherine Lindsay Lucot

Department of Animal Science: Dissertations, Theses, and Student Research

Including marker-assisted selection in breeding programs is potentially more efficient than traditional selection for improving traits that are expensive or difficult to measure. One of the challenges of genomics is the lack of robustness of marker effects across populations and over time (generations) and the cost to commercial producers of high-density arrays. The objective of this study was to analyze differences in the proportion of phenotypic variation explained by different fractions of major 1 Mb windows and SNPs. Using a population of Nebraska Index Line and commercial Large White x Landrace females (n = 1,234) generated in 11 batches, …

The Detection Of Amazonian Manatees (Trichechus Inunguis) Using Side-Scan Sonar And The Effect Of Oil Activities On Their Habitats In Eastern Ecuador, Caitlin E. Brice

HCNSO Student Theses and Dissertations

Substantial hunting pressure and habitat destruction caused by oil extraction has critically endangered the Amazonian manatee in Ecuador. The current population status is unknown because an effective method to observe them in the wild has yet to be developed. This study explored whether the Amazonian manatee persists or has been extirpated in the eastern Ecuadorian Amazon utilizing side-scan sonar to increase odds of detection. Spatial differences in probability of detection were quantified if manatees were observed. The level of chemical contamination was determined and compared spatially and temporally against historical data. Data were collected using opportunistic transect surveys and grab …

Forage News [2014-05], Department Of Plant And Soil Sciences, University Of Kentucky

Forage News

• Kentucky Grazing School
• Milestone Forage Program Dates
• Hay Quality
• Mountain Ag Week at UK Robinson Center
• Forage Recovery from the Winter of 2013/14
• Hay Harvest Stage Impacts Quality
• KFGC Field Day

An Examination Of The Feasiblity Of A Food Hub For The Pee Dee Region, Emily Purcell

All Theses

Horry County, the home of Myrtle Beach, South Carolina, attracts a large level of spending by visitors who are helping to fuel growing demand for locally produced food. Regional growers are interested in meeting this demand but are limited by retail requirements with respect to lot size, timing, and quality (including food safety aspects such as Good Agricultural Practices (GAP) certification). A number of communities have turned to food hubs as a means of aggregating production by local growers and providing appropriate marketing functions, such as storage and meeting standards. Hence, food hubs can fill a gap between producers and …

Comprehensive Cancer Care: An Outpatient Treatment Facility, Braden Abrams Reid

All Theses

A cancer diagnosis can result in a loss of decision-making and control for patients. The majority of clinical treatments fail to adequately address corollary symptoms and needs that arise both from treatment and from the disease itself. Thus, the architectural problem identified in this thesis inquiry is how can an outpatient cancer centre treat the whole patient comprehensively, while at the same time instilling control and re-empowering the patient? This thesis project proposes a patient-centered environment designed to support the myriad and nuanced needs of the cancer patient, as well as a site-specific proposal for a comprehensive outpatient cancer treatment …

The Missouri Miner, May 1, 2014

The Missouri Miner Newspaper

No abstract provided.

Using The Theory Of Planned Behavior To Explain Physical Activity Among College Students, Ese B. Aghenta

Masters Theses & Specialist Projects

The health benefits of physical activity include improved cardiovascular health, reduced rates of diabetes and other metabolic diseases, weight maintenance and improved bone and mental health (United States Department Health & Human Services (2008). According to the American College Health Association National College Health Assessment (ACHA-NCHA, 2013), only 20.0% of college students in the United States meet this recommendation. The Theory of Planned Behavior (TPB) attempts to explain the intention to perform behaviors that are not under an individual’s complete volitional control and has been highly utilized in predicting intention and performance of physical activity (Courneya, Nigg & Estabrooks, 1998). …

Effects Of Jump Training On Bone Mineral Density In Young Adult Females, Battogtokh Zagdsuren

Masters Theses & Specialist Projects

Physical activity is critical to bone health. However, not all physical activity has optimum effect on bone health and metabolism. The purpose of this study was to determine the effects of a short term progressive jumping protocol on bone mineral density in college age Asian females. Sixteen participants aged18-28 years enrolled in the study. Participants were assigned to exercise (n=9) and control (n=8) groups. The exercise group completed a two-legged depth jump from an approximate 20cm stepbench followed immediately by a maximum vertical jump using arm swings for five days per week for two weeks. Each depth jump and vertical …

Visual Analysis And Design Proposal For The Bridges Organization Day Facility In Rockledge, Florida, Lesa N. Lorusso

Architecture Masters of Science Program: Theses

The population by age of the client and staff at the Bridges Facility in Rockledge, Florida represent a microcosm of the population of Brevard County, Florida. The shared history of two non-profit organizations that began in in Brevard County, FL in the mid twentieth century is remarkable. NASA began in 1958, and the Bridges organization began in 1956. The historically significant American community of Brevard County, FL now faces the challenges of a new focus without the NASA space shuttle program and accommodating an increasingly aging population, while the similarly aged Bridges organization faces similar organizational and population challenges as …

College Students’ Use Of Farmers’ Markets In Lincoln, Nebraska, Amber Reinkordt

Department of Environmental Studies: Undergraduate Student Theses

The purpose of this study is to develop an understanding of college students’ use of local farmers’ markets in Lincoln, Nebraska and the barriers that prevent college students from attending farmers’ markets, and noting the incentives that could motivate them to attend.

Currently there are no research articles about college students and their attendance at farmers' markets. There are, however, articles pertaining to getting students on the farm, school gardens, low income families and making farmers' markets more accessible and affordable, health benefits for customers who shop locally, and environmental, economic, and societal benefits of local farm operations.

An Evaluation Of The East Indianapolis Food Desert, Angelina Qin

Undergraduate Honors Thesis Collection

The Indy East Food Desert (IEFD) appears to suffer from many common conditions noted by various scholars as food desert identifiers. Yet, its situation still remains unique. Though there is a prevalence of minority populations, low-income households, and low-education attainment levels, there are also factors of low-access, poor food options (within the limited food outlets in the neighborhoods), and poor eating habits which shape the situation of the community. In an attempt to alleviate the food desert problems, the Indy East Food Desert Coalition (IEFDC) was formed. IEFDC partnered with Butler University's Center for Urban Ecology in order to assess …

Creating Course Curriculum For A Community College, Carol E. Reis

Creativity and Change Leadership Graduate Student Master's Projects

ABSTRACT OF A PROJECT

Creating college courses for a community college is the main focus of this project. The specific college is Erie Community College in Western New York. Three areas of course development that have been targeted are: recreation, creative studies, and therapeutics.

Just as the needs in society change, the need for a college to change to fit the needs of society coexists. A function of higher education is to train students to be competitive in the existing job market. The final outcome of a college certificate and/or degree is best suited to students if the certificates and …

Effect Of Low And High Molecular Weights Water Soluble Chitosan On Oxidation Of Whole Milk Powder, Wesam Al-Jeddawi

All Theses

Autoxidation significantly decreases the shelf life of whole milk powder due to primary and secondary oxidation products such as hydroperoxides, aldehydes, ketones, alcohols and hydrocarbons. Water soluble chitosan has been shown to reduce oxidation by chelating metals or combining with lipids resulting in a significant antioxidative effect. The objective of this study was to determine the antioxidative effects of different concentrations of low (L) and high (H) molecular weight water soluble chitosan (9 and 90 kDa, respectively) on whole milk powder (WMP). Commercially dried WMP was obtained and rehydrated 50% (wt/wt) with various aqueous chitosan solutions (2% L2, 4% L4, …

In Search Of Ubuntu: An Examination Of Enslaved African Domestic And Labor Environments On St. Eustatius, Deanna Lynn Byrd

Theses and Dissertations

The discovery of dry stone rock features in the northern hills on the Dutch island of St. Eustatius presented a unique opportunity to investigate an enslaved African environment during the time of enslavement. Abandoned after emancipation, the area has remained virtually undisturbed by eco-tourism, making it an archaeological gem. The intact nature of the sites held potential to add significantly to our understanding of choices enslaved Africans made in slave village design, orientation, and the construction of their dwellings, as well as the labor activities of daily life. In doing so, this investigation attempted to detect whether higher levels of …

The Reference Transcriptome Of The Adult Female Biting Midge (Culicoides Sonorensis) And Differential Gene Expression Profiling During Teneral, Blood, And Sucrose Feeding Conditions, Dana Nayduch, Matthew B. Lee, Christopher Saski

Publications

Unlike other important vectors such as mosquitoes and sandflies, genetic and genomic tools for Culicoides biting midges are lacking, despite the fact that they vector a large number of arboviruses and other pathogens impacting humans and domestic animals world-wide. In North America, female Culicoides sonorensis midges are important vectors of bluetongue virus (BTV) and epizootic hemorrhagic disease virus (EHDV), orbiviruses that cause significant disease in livestock and wildlife. Libraries of tissue-specific transcripts expressed in response to feeding and oral orbivirus challenge in C. sonorensis have previously been reported, but extensive genome-wide expression profiling in the midge has not. Here, we …

Lowering Somatic Cell Count With Best Management Practices, Stephen F. Higgins, Kylie Schmidt, Sarah Wightman

Agriculture and Natural Resources Publications

As health and food safety concerns grow, dairy producers are facing more stringent regulations. In 2010, the European Union (EU) set the somatic cell count (SCC) upper limit, an indicator of milk quality, for exported milk at 400,000 cells per milliliter. However, the current U.S. SCC limit is 750,000 cells per milliliter. As of January 2012, any U.S. milk used in export markets must meet the EU standards. It is projected that US milk processors will gradually adopt the EU upper limit, making it difficult for dairy producers to sell milk containing more than 400,000 somatic cells per milliliter. Dairy …

An Ipm Scouting Guide For Common Problems Of Apple In Kentucky, Nicole Ward Gauthier, Ricardo Bessin, John Strang, Shawn Wright, Cheryl A. Kaiser

Agriculture and Natural Resources Publications

The National Integrated Pest Management Network defines IPM as “a sustainable approach to managing pests by combining biological, cultural, physical and chemical tools in a way that minimizes economic, health, and environmental risks.” One of the key components of IPM is to continually scout and monitor crops to identify problems before they result in significant economic losses. Proper identification of pathogens and insect pests as well as nutritional and physiologic disorders and even herbicide drift is essential to determining the proper course of action. The pictures included in this guide represent some common pests or problems that growers may encounter …

Gender Differences And Impact On Addictions Treatment: Special Consideration For Working With Female Clients, Amy Horihan

Counselor Education Capstones

Special considerations when working with women with substance use disorders were assessed in comparison to male counterparts. Topics included gender differences relating to physiological, psychological and socio-cultural spheres. Treatment considerations related to trauma sensitivity, marginalization and stigma were addressed. Special considerations relating to female racial minority populations were evaluated and explored. Research included a comprehensive literature review of peer-reviewed journal articles, research studies and government report findings covering multiple disciplines: counseling, neuropsychology, medical, criminal justice and social work. Findings of this research revealed significant diversity and complexity within the American population of females struggling with chemical addiction. Due to this …

Depression And Risk Perceptions In Older African Americans With Diabetes, Barry W. Rovner, Md, Julia A. Haller, Md, Robin J. Casten, Phd, Ann P. Murchison, Md, Mph, Lisa A. Hark, Phd, Rd

Department of Psychiatry and Human Behavior Faculty Papers

Introduction: The purpose of this study is to describe the impact of depression on perceptions of risks to health, diabetes self-management practices, and glycemic control in older African Americans with type 2 diabetes.

Methods: The authors analyzed data on depression, risk perceptions, diabetes self-management, and hemoglobin A1C in African Americans with type 2 diabetes.T tests, chi square, and multivariate regression were used to analyze the data.

Results: The sample included 177 African Americans (68% women) whose average age was 72.8 years. Thirty four (19.2%) participants met criteria for depression. Compared to non-depressed participants, depressed participants scored significantly higher on Personal …

Alendronate Alters Single Cell Gene Expression Of Cortical Osteoblast Lineage Cells During Bone Loss, Ryan Jakob Murphy

Dissertations, Masters Theses, Capstones, and Culminating Projects

The mineralized matrix of bone makes it difficult to examine specific populations of cells which are integral to the tissue using traditional molecular methods. For this study we examined single cell cortical osteoblasts derived from the femurs of C57BL/6J mice. After isolating single cells from bone, we were able to individually analyze their gene expression profiles using the quantitative polymerase chain reaction (qPCR). The mice used for the study were divided into 4 treatment groups, including ovariectomized mice (OVX) and sham surgical controls (SHAM), treated with or without the anti-resorptive bisphosphonate drug Alendronate, an effective FDA approved therapeutic for slowing …

Application Of High-Performance Liquid-Chromatography Mass-Spectrometry Platform To Study Metabolism And Epigenetic Control Of Metabolism, Kylie Patricia Mitchell

Dissertations, Masters Theses, Capstones, and Culminating Projects

Naturally occurring small molecules (metabolites, signaling intermediates) are a critical component of the information flow in biology, along with DNA, RNA, and proteins. Metabolomics is an analytical approach that seeks to comprehensively analyze naturally occurring small molecules and quantify their dynamic changes in biological systems. In recent years metabolomics has begun to provide understanding of the metabolic basis of different diseases, such as heart disease, cancer, and diabetes. Our lab built a High-Performance Liquid-Chromatography Mass-Spectrometry (HPLC-MS) based metabolomics platform to analyze metabolites from mammalian cells, spent cellular media, and model organisms such as C. elegans. We used C. elegans to …