Digital Commons Network^™

Cellular And Molecular Regulation Of Skeletal Muscle Regeneration, Chunhui Jiang

Open Access Dissertations

Skeletal muscle regeneration provides a powerful model to study the cellular and molecular mechanism governing stem cell function since the whole process is mediated by a population of muscle-resident stem cells called satellite cells. The overall aim of this dissertation is to explore the roles of Notch signaling and a novel gene (Bex1) in satellite cell function and skeletal muscle regeneration. ^ The first part of this thesis is to examine how the Notch signaling pathway regulates the satellite cell self-renewal in a disease model. The MDX mouse is a well-established model for Duchenne muscular dystrophy (DMD) and characterized by …

Karyopherin Alpha Subtypes And Porcine Early Stage Embryo Development, Yanfang Li

Open Access Dissertations

Intracellular communication between the nucleus and cytoplasm is critically important for coordinating cellular events during embryogenesis. The karyopherin α/β heterodimer is an intracellular nuclear trafficking system that mediates nuclear import of proteins that bear classical nuclear localization signals (NLSs). Seven karyopherin α subtypes have been identified in the domestic pig, and while each of these karyopherin α subtypes is able to bind to a nuclear localization signal, individual karyopherin α subtypes have been shown to transport specific NLS-bearing proteins. The objective of this study was to determine the developmental requirements of karyopherin α subtypes (KPNAs) during cleavage development in porcine …

Energy Production, Distribution, And Pollution Controls: Combining Engineering And Economic Analysis To Enhance Efficiency And Policy Design, David F. Perkis

Open Access Dissertations

Three published articles are presented which focus on enhancing various aspects of the energy supply chain. While each paper adopts a different methodology, all three combine engineering data and/or techniques with economic analysis to improve efficiency or policy design within energy markets. ^ The first paper combines a chemical engineering plant design model with an economic assessment of product enhancements within an ethanol production facility. While a new chemical process is shown to achieve greater ethanol yields, the animal feed by-products are denatured and decrease in value due to the degradation of a key nutritional amino acid. Overall, yield increases …

Soil Quality And Nitrogen Cycling Dynamics Altered By Fertility Amendments In Intensively Managed Vegetable Production Systems, Matt A. Rudisill

Open Access Dissertations

Fresh market vegetable production in the Midwest U.S. is growing rapidly as a result of increased demand for locally-sourced food. High tunnels are becoming increasingly popular among Midwest vegetable growers as these structures offer many production benefits including season extension. However, vegetables require substantial fertility inputs, particularly nitrogen (N), in order to meet desired levels of productivity, and some fertility management strategies can negatively impact soil and environmental quality. This can be particularly problematic in high tunnels, where longer production periods and modification of the growing environment put these systems at greater risk for soil degradation. Identification of fertility practices …

Host Cell Death In Legionella Pneumophila Pathogenesis And Immunity, Wenhan Zhu

Open Access Dissertations

Legionella pneumophila is an intracellular pathogen that causes a severe, atypical pneumonia termed Legionnaires' disease. Upon entering the host cell, L. pneumophila resides in a membrane-bound vacuole, in which the bacterium evades lysosomal fusion and replicates. The establishment of the vacuole requires the Dot/Icm (Defect in organelle trafficking/ intracellular multiplication) transport system, which translocates a large number of substrates into host cells to re-orchestrate various cellular processes, such as intracellular trafficking, protein synthesis and host cell death pathways. Therefore, a key step in understanding the biology of Legionella is to dissect the mechanisms of action of the Dot/Icm substrates. By …

African Starchy Foods, Gastric Emptying, And Starch Digestion In Malian Stunted Children, Fatimata Cisse

Open Access Dissertations

Starch serves as the main energy source in cereal and tuber-rich diets, and its glycemic response profile has been associated with health-related conditions. Sorghum and millet are known to have relatively low starch digestibility, a potentially desirable property for controlling blood glucose response and providing sustained energy. Gastric emptying rates of traditional sorghum and millet-based African foods of the Sahelian region (couscous, thick and thin porridges made from millet and/or sorghum) were compared to those of non-traditional "modern" foods that are mostly consumed in urban areas using a non-invasive 13C-labelled octanoic acid breath test in healthy volunteers. The obtained results …

Evaluating The Student Health Needs At Dalton State College, Cheryl W. Owens

Doctor of Nursing Practice (DNP) Translational and Clinical Research Projects

The incidence of chronic diseases in college students mirrors that of older adults. Yet despite the enactment of the Affordable Care Act (ACA), college student continue to have difficulty accessing medical care. Many have no insurance, limited transportation and inadequate finances during college to obtain medical care. While college health centers may improve access to care, smaller colleges often do not have the financial and personnel resources to provide student health services. Even in colleges that provide student health services, the focuses are primarily on sexual health, mental health, violence, and substance abuse. Prevention and treatment of chronic diseases services …

Nurse Practitioner Screening Practices For Mild Cognitive Impairment In The Older Adult, Margaret Mcilwain

Doctor of Nursing Practice (DNP) Translational and Clinical Research Projects

Abstract

Nurse practitioners (NPs/APRNs) who provide primary care services may be the first line providers in situations where adults present with symptoms of memory loss and forgetfulness. Though protocols are available for evaluating dementia, specific guidelines for evaluating early cognitive changes, Mild Cognitive Impairment (MCI), are lacking. This descriptive research project assesses the knowledge, current screening methods, and barriers to screening for MCI by nurse practitioners (APRNs) in the state of Georgia. One hundred and thirty two NPs participated in the survey. Forty-five percent of the participants were unfamiliar with the diagnostic category of MCI. Of the major barriers identified, …

2014-October-01-Child Study Center To Introduce 'Rainbow In My Tummy' Menu, Nutrition Progra, University Marketing And Communications, East Tennessee State University

ETSU News

No abstract provided.

Admit That The Waters Around You Have Grown: Change And Legal Education, Mari J. Matsuda

Indiana Law Journal

Presented as the Addison C. Harris Lecture at Indiana University Maurer School of Law, Bloomington, Indiana, September 25, 2013.

The Medical Device Excise Tax: An Unfair Burden, Elizabeth M. Bolka

Indiana Law Journal

No abstract provided.

Youth Transitions Advisory Council Annual Report 2014, Tennessee. Commission On Children And Youth.

Youth Transitions Advisory Council

No abstract provided.

Nebline, October 2014

NEBLINE Newsletter Archive from Nebraska Extension in Lancaster County

Feature: Smart Snacking

Food & Health

Family Living

Farm & Acreage

Home & Family Living

Horticulture

Pests & Wildlife

4-H & Youth

Extension Calendar

and other extension news and events

Staphylococcus Aureus Hyaluronidase Is A Cody-Regulated Virulence Factor, Carolyn B. Ibberson, Crystal L. Jones, Shweta Singh, Matthew C. Wise, Mark E. Hart, Daniel V. Zurawski, Alexander R. Horswill

United States Army: Publications

Staphylococcus aureus is a Gram-positive pathogen that causes a diverse range of bacterial infections. Invasive S. aureus strains secrete an extensive arsenal of hemolysins, immunomodulators, and exoenzymes to cause disease. Our studies have focused on the secreted enzyme hyaluronidase (HysA), which cleaves the hyaluronic acid polymer at the β-1,4 glycosidic bond. In the study described in this report, we have investigated the regulation and contribution of this enzyme to S. aureus pathogenesis. Using the Nebraska Transposon Mutant Library (NTML), we identified eight insertions that modulate extracellular levels of HysA activity. Insertions in the sigB operon, as well as in genes …

Sport Management Report 2014-2015, Sport Management Discipline

Assessment of Student Learning Reports

No abstract provided.

Faubion Pk-8 School: Daylight Analysis, Sergio Palleroni, Haufen Hu, Adam Mcsorley, Katherine Odell, Valeriya Shcheglova, Boora Architects

Research-Based Design Initiative

Light is the first thing that captures your eye after you are born and is often the last th ing you see before you fall asleep. Light makes humans, objects, spaces, architecture and everything we see around us visib le by its reflection. Everyday, people are confronted with light and shadow, two elements that are complementary. Daylight is a natu ral element that changes every minute, caused by the rotation of the earth around the sun. It informs us of days, time, seasons, which causes humans have to surrender to this. Architecture must adapt this element in its design process. …

Tinkering With Success: College Athletes, Social Media And The First Amendment, Meg Penrose

Faculty Scholarship

Good law does not always make good policy. This article seeks to provide a legal assessment, not a policy directive. The policy choices made by individual institutions and athletic departments should be guided by law, but absolutely left to institutional discretion. Many articles written on college student-athletes' social media usage attempt to urge policy directives clothed in constitutional analysis.

In this author's opinion, these articles have lost perspective-constitutional perspective. This article seeks primarily to provide a legal and constitutional assessment so that schools and their athletic departments will have ample information to then make their own policy choices.

Estimation Of Nitrogen Vertical Distribution By Bi-Directional Canopy Reflectance In Winter Wheat, Wenjiang Huang, Qinying Yang, Ruiliang Pu, Shaoyuan Yang

School of Geosciences Faculty and Staff Publications

Timely measurement of vertical foliage nitrogen distribution is critical for increasing crop yield and reducing environmental impact. In this study, a novel method with partial least square regression (PLSR) and vegetation indices was developed to determine optimal models for extracting vertical foliage nitrogen distribution of winter wheat by using bi-directional reflectance distribution function (BRDF) data. The BRDF data were collected from ground-based hyperspectral reflectance measurements recorded at the Xiaotangshan Precision Agriculture Experimental Base in 2003, 2004 and 2007. The view zenith angles (1) at nadir, 40° and 50°; (2) at nadir, 30° and 40°; and (3) at nadir, 20° and …

The Influences Of The Musselman Family, Yifei Zhang

Student Publications

For almost a century, the Musselman family has had huge influences on Adams County, PA. Many of those contributions are unknown by people today. So, based on the research of the Musselman Canning Company and the two Musselman Foundations, this paper is a study of the impacts the Musselman family has had on others and how it has achieved that influence. The main primary sources include the company’s publication, The Processor, the articles on local newspaper, and the collections in the Special Collection in Gettysburg College’s Musselman Library.

Regulation Of Peripheral Molecular Clocks In Mammalian Tissues And In Vitro Skeletal Muscle Activation Of Amp-Activated Protein Kinase Via Aicar, Alex C. Lupolt, Daniel P. Moorhead, Josef Brandauer

Student Publications

Most organisms possess a common molecular machinery that governs cellular and tissue circadian rhythmicity through a roughly 24-hour transcription-translation feedback loop. It is estimated that up to 15 percent of human genes are influenced by the core clock machinery. It is likely, however, that the metabolic networks affected by the molecular clock differ according to body tissue.

Recent evidence suggests that peripheral molecular clocks are governed to a greater extent by energy availability than by light and dark cycles. AMP-activated protein kinase (AMPK) acts as a cellular fuel gauge within the cell and is activated in response to exercise and …

“In Light Of Real Alternatives”: Negotiations Of Fertility And Motherhood In Morocco And Oman, Victoria E. Mohr

Student Publications

Many states in the Arab world have undertaken wide-ranging family planning polices in the last two decades in an effort to curb high fertility rates. Oman and Morocco are two such countries, and their policies have had significantly different results. Morocco experienced a swift drop in fertility rates, whereas Oman’s fertility has declined much more slowly over several decades. Many point to the more conservative religious and cultural context of Oman for their high fertility rates, however economics and the state of biomedical health care often present a more compelling argument for the distinct differences between Omani and Moroccan family …

College Of Health Sciences Newsletter, October 2014, College Of Health Sciences, Odu

Ellmer College of Health Sciences Newsletters

October 2014 issue of Old Dominion University's College of Health Sciences Newsletter.

Beyond Sustainability: A New Conceptual Model, Molly Kerby, Gayle Mallinger

eJournal of Public Affairs

Over the last few decades, the notion of sustainability has become an interdisciplinary buzz word. Sustainability has been an integrative concept that includes three constructs or pillars: a) social; b) economic; and c) ecological. Until recently, theoretical approaches based on the three pillars approach have operated in silos rather than exploring the interconnectedness of the constructs. Few models have moved beyond the idea that logical relations exist among the constructs (social, economic, and ecological) to consider factors external to communities, nor have they examined the internal socio-economic factors that influence positive outcomes. While this conceptualization has raised awareness about the …

Economic Changes, Policy Changes: The First Major Effect Of The Green Revolution, Diego Masi

eJournal of Public Affairs

The Green Economy is something more than the sum of all possible related efforts to create a “green” turning point in the economy. It is a revolution of the way of life of the inhabitants of the planet to try to change a system that is leading us to self-destruction. The facts speak for themselves: the human factor is affecting the climate with vast greenhouse gas emissions due not only to the exploitation of fossil fuels but also to deforestation, agriculture and intensive livestock farms, and of course industrialization. The Green Revolution is thus the first collective effort to save …

International Collaboration In Higher Education: Using The Systems Thinking Approach To Negotiate A Memorandum Of Understanding (Mou): The Case West Chester University, West Chester, Pa, And University Rafael Landívar, Url, Guatemala, María Elena Arias-Zelidón, Ana C. Sánchez

Languages & Cultures Faculty Publications

No abstract provided.

Research: South Dakota State University, Fall 2014, Christie Delfanian, Dave Graves, Emily Weber

State of Discovery South Dakota State University's Research Magazine

CONTENTS:

Dietician seeks to reduce obesity among college-age students [Page] 2
Wind: Support for wind energy based in economic development [Page] 3
Berg leaves legacy of accomplishments [Page] 3
Soil: Improved soil condition increases moisture for crops [Page] 4
Microbial process increases soybean meal's protein power [Page] 5
Medgene develops vaccines using university technologies [Page] 6
BioSNTR funding boosts biotechnology in South Dakota [Page] 8
Scientists collaborate to combat avian influenza [Page] 8
Pharmacy students role-play as part of a health-care team [Page]10
Nursing research seeks to improve health care, reduce costs [Page 10]
Improving organic solar cell efficiency essential …

Fall 2014, Gla Glq

Georgia Library Quarterly

No abstract provided.

Advertisement - Very Short Introductions, Oxford University Press, Gla Glq

Georgia Library Quarterly

No abstract provided.

Full Court Press: Northwestern University, A New Challenge To The Ncaa, William B. Gould Iv, Glenn M. Wong, Eric Weitz

Loyola of Los Angeles Entertainment Law Review

In recent years, a host of issues have arisen between the National Collegiate Athletic Association (NCAA) and the college athletes who provide the labor from which the NCAA and its member universities derive their profits. Many of these issues have been heavily publicized and have spurred a heated debate over the status of college athletes and the future of the collegiate athletic system. This Article primarily focuses on the issue of college athletes’ status as employees for purposes of federal labor law. The significant increase in the popularity of college sports in recent years has led to conference realignment, facility …

Ecophysiological Effects Of Nitrogen On Soybean [Glycine Max (L.) Merr.], Ifeanyi Onor, Gabriel Onor, Murty Kambhampati

Faculty and Staff Publications

Soybean [Glycine max (L.) Merr.] is a leguminous plant with high nutritional and medicinal value. The goal of this research was to determine the optimal concentration of nitrogen, using Hoagland nutrient solution, which will enhance the productivity of soybeans. The specific objective of the study was to assess the effect of variation of nitrogen concentration on soybean growth and leaf chlorophyll concentrations. Soybeans were grown under three soil nitrogen amendments: low, medium, and high concentration of Hoagland nutrient solution and a control group. Soybeans were grown under controlled environmental conditions in the Biotronette? environmental chamber. Temperature of the environmental chamber …