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2014

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Hydroxyapatite, Fluor-Hydroxyapatite And Fluorapatite Produced Via The Sol–Gel Method: Dissolution Behaviour And Biological Properties After Crystallisation, Cj Tredwin, Am Young, Ea Abou Neel, G Georgiou, Jc Knowles Jan 2014

Hydroxyapatite, Fluor-Hydroxyapatite And Fluorapatite Produced Via The Sol–Gel Method: Dissolution Behaviour And Biological Properties After Crystallisation, Cj Tredwin, Am Young, Ea Abou Neel, G Georgiou, Jc Knowles

Peninsula Dental School

Hydroxyapatite (HA), fluor-hydroxyapatite (FHA) with varying levels of fluoride ion substitution and fluorapatite (FA) were synthesised by the sol-gel method as possible implant coating or bone-grafting materials. Calcium nitrate and triethyl phosphite were used as precursors under an ethanol-water based solution. Different amounts of ammonium fluoride were incorporated for the preparation of the FHA and FA sol-gels. After heating and powdering the sol-gels, dissolution behaviour was assessed using ion chromatography to measure Ca(2+) and PO4 (3-) ion release. Biological behaviour was assessed using cellular proliferation with human osteosarcoma cells and alamarBlue™ assay. Statistical analysis was performed with a two way …


Evaluation Of The Microbial Community, Acidity And Proximate Composition Of Akamu, A Fermented Maize Food, Patience C. Obinna-Echem, Victor Kuri, Jane Beal Jan 2014

Evaluation Of The Microbial Community, Acidity And Proximate Composition Of Akamu, A Fermented Maize Food, Patience C. Obinna-Echem, Victor Kuri, Jane Beal

School of Biological and Marine Sciences

No abstract provided.


Insulin Acutely Improves Mitochondrial Function Of Rat And Human Skeletal Muscle By Increasing Coupling Efficiency Of Oxidative Phosphorylation., Raid B. Nisr, Charles Affourtit Jan 2014

Insulin Acutely Improves Mitochondrial Function Of Rat And Human Skeletal Muscle By Increasing Coupling Efficiency Of Oxidative Phosphorylation., Raid B. Nisr, Charles Affourtit

School of Biomedical Sciences

Insulin is essential for the regulation of fuel metabolism and triggers the uptake of glucose by skeletal muscle. The imported glucose is either stored or broken down, as insulin stimulates glycogenesis and ATP synthesis. The mechanism by which ATP production is increased is incompletely understood at present and, generally, relatively little functional information is available on the effect of insulin on mitochondrial function. In this paper we have exploited extracellular flux technology to investigate insulin effects on the bioenergetics of rat (L6) and human skeletal muscle myoblasts and myotubes. We demonstrate that a 20-min insulin exposure significantly increases (i) the …


A Workflow For Bacterial Metabolic Fingerprinting And Lipid Profiling: Application To Ciprofloxacin Challenged Escherichia Coli, J. William Allwood, Haitham Alrabiah, Elon Correa, Andrew Vaughan, Yun Xu, Mathew Upton, Royston Goodacre Jan 2014

A Workflow For Bacterial Metabolic Fingerprinting And Lipid Profiling: Application To Ciprofloxacin Challenged Escherichia Coli, J. William Allwood, Haitham Alrabiah, Elon Correa, Andrew Vaughan, Yun Xu, Mathew Upton, Royston Goodacre

School of Biomedical Sciences

No abstract provided.


A Novel Phosphatidylinositol 3-Kinase (Pi3k) Inhibitor Directs A Potent Foxo-Dependent, P53-Independent Cell Cycle Arrest Phenotype Characterized By The Differential Induction Of A Subset Of Foxo-Regulated Genes, Richard Hill, Ravi Kiran Reddy Kalathur, Sergio Callejas, Laura Colaço, Ricardo Brandão, Beatriz Serelde, Antonio Cebriá, Carmen Blanco-Aparicio, Joaquín Pastor, Matthias Futschik, Ana Dopazo, Wolfgang Link Jan 2014

A Novel Phosphatidylinositol 3-Kinase (Pi3k) Inhibitor Directs A Potent Foxo-Dependent, P53-Independent Cell Cycle Arrest Phenotype Characterized By The Differential Induction Of A Subset Of Foxo-Regulated Genes, Richard Hill, Ravi Kiran Reddy Kalathur, Sergio Callejas, Laura Colaço, Ricardo Brandão, Beatriz Serelde, Antonio Cebriá, Carmen Blanco-Aparicio, Joaquín Pastor, Matthias Futschik, Ana Dopazo, Wolfgang Link

School of Biomedical Sciences

No abstract provided.


Evidence That Duplications Of 22q11.2 Protect Against Schizophrenia, E Rees, G Kirov, Mc O'Donovan, Wellcome Trust Case Control Consortium, Et Al Jan 2014

Evidence That Duplications Of 22q11.2 Protect Against Schizophrenia, E Rees, G Kirov, Mc O'Donovan, Wellcome Trust Case Control Consortium, Et Al

School of Biomedical Sciences

A number of large, rare copy number variants (CNVs) are deleterious for neurodevelopmental disorders, but large, rare, protective CNVs have not been reported for such phenotypes. Here we show in a CNV analysis of 47 005 individuals, the largest CNV analysis of schizophrenia to date, that large duplications (1.5-3.0 Mb) at 22q11.2--the reciprocal of the well-known, risk-inducing deletion of this locus--are substantially less common in schizophrenia cases than in the general population (0.014% vs 0.085%, OR=0.17, P=0.00086). 22q11.2 duplications represent the first putative protective mutation for schizophrenia.


A Strategy To Engage Islamic Youth And Young Adults In Grand Cape Mount County, Liberia, Matthew F. Kamara Jan 2014

A Strategy To Engage Islamic Youth And Young Adults In Grand Cape Mount County, Liberia, Matthew F. Kamara

Doctor of Ministry Projects

Problem. Since the arrival of the first official Adventist missionaries to Liberia in 1926, evangelistic efforts have been focused on non-Muslim communities. The nation’s 14 years of civil crisis left 105,000 disarmed combatants who are mainly young people. Most of these young people are found in Grand Cape Mount County, a predominantly Islamic community where they are engaged in illicit diamond mining, illegal harvesting of latex, and other criminal activities for their income. There is a need for the Adventist church to use this situation as an opportunity to reach out to them with pilot projects that will empower them …


The Impact Of Media On The Morality Of Young Adventist Church People In The Nairobi Central Church, Alex Ambuchi Jan 2014

The Impact Of Media On The Morality Of Young Adventist Church People In The Nairobi Central Church, Alex Ambuchi

Doctor of Ministry Projects

Problem

Young people in urban areas are especially affected by the liberal trends of the media industry.The media advertises and broadcasts programs that promote immoral behaviors among young people. The Nairobi Central Seventh-day Adventist Church is located in the capital city of Kenya and the negative effects of the media have impacted the youth of this church.

Method

The strategy involved sensitizing Adventist youth concerning the negative impact of the media on morality. A theology of morality and purity was developed and a description of the context for the project conducted. I then used the logical framework and the Gantt …


A Biblical And Theological Strategy For Dealing With Spiritualism In The Zambian Context, Peter Chulu Jan 2014

A Biblical And Theological Strategy For Dealing With Spiritualism In The Zambian Context, Peter Chulu

Doctor of Ministry Projects

Problem

Rusangu Secondary School has experienced many incidents in recent years where dorm students were harassed by evil spiritual forces, causing fear and uncertainty among the students.

Method

A systematic study of the Bible, commentaries, books, journals, and articles concerning spiritualism was undertaken. Once theological and historical data on spiritualism was identified, it was utilized for training, equipping, and empowering prayer band members on how to deal with demonic harassment at the school.

Results

The school and church experienced revitalization. Members learned how to utilize a prayer band ministry to pray for the students who were being harassed by evil …


The Social Cost Of Of Inertia: How Cost-Benefit Incoherence Threatens To Derail U.S. Climate Action, Melissa Luttrell Jan 2014

The Social Cost Of Of Inertia: How Cost-Benefit Incoherence Threatens To Derail U.S. Climate Action, Melissa Luttrell

Articles, Chapters in Books and Other Contributions to Scholarly Works

No abstract provided.


Jerusalem In The Courts And On The Ground, Sam Halabi Jan 2014

Jerusalem In The Courts And On The Ground, Sam Halabi

Articles, Chapters in Books and Other Contributions to Scholarly Works

No abstract provided.


Desarrollo E Implementacion De Una Escuela De Capacitation Laica Para La Union Colombiana Del Sur, Jose Aicardo Arias Quintero Jan 2014

Desarrollo E Implementacion De Una Escuela De Capacitation Laica Para La Union Colombiana Del Sur, Jose Aicardo Arias Quintero

Doctor of Ministry Projects

Problem. The South Colombian Union (SCU) was established in 2010. Because of its recent organization, the Union does not have a well-organized lay training program, to fulfill its mission. The formation of a lay training school will greatly contribute with the formation of new leaders, as well with the dissemination of the gospel in the region.

Methodology. This research begins with a theological study related to the training of laity for evangelism, followed by a review of current literature on training lay people for ministry. To meet the goal to train lay leaders’ for ministry, the SCU adopted, contextualized, and …


Summit Report: Freedom Of The Press In The Twenty-First Century – An Agenda For Thought And 
Action - Panel Iv: The Future Of The Press And Secrecy, Jeffery A. Smith, Robert E. Drechsel, W. Wat Hopkins, Derigan Silver, Erik Ugland Jan 2014

Summit Report: Freedom Of The Press In The Twenty-First Century – An Agenda For Thought And 
Action - Panel Iv: The Future Of The Press And Secrecy, Jeffery A. Smith, Robert E. Drechsel, W. Wat Hopkins, Derigan Silver, Erik Ugland

College of Communication Faculty Research and Publications

No abstract provided.


How Corporations Manage Industry And Consumer Expectations Via The Csr Report, Sarah Bonewits Feldner, Kati Tusinski Berg Jan 2014

How Corporations Manage Industry And Consumer Expectations Via The Csr Report, Sarah Bonewits Feldner, Kati Tusinski Berg

College of Communication Faculty Research and Publications

With increased stakeholder scrutiny, it is increasingly salient to consider how corporations make the case that their CSR activities are sufficient, appropriate, and successful. The CSR report is the vehicle by which organizations communicate the breadth of activities they engage in to make a difference in society. Using rhetorical analysis and surveys, we argue that the CSR report functions as a means by which corporations manage stakeholder expectations and seek to legitimate corporate behaviors. Our findings indicate that most reports are structured based on external guidelines but include the use of classic rhetorical strategies of ethos, pathos, and logos to …


The Role Of Country Of Origin In Brand Following On Social Media Among U.S. Consumers, Jim Pokrywczynski, Kevin Keenan Jan 2014

The Role Of Country Of Origin In Brand Following On Social Media Among U.S. Consumers, Jim Pokrywczynski, Kevin Keenan

College of Communication Faculty Research and Publications

An understanding of how consumers interact with brands online is still in its infancy. This study will attempt to explain what motivates consumers to follow brands on social media, looking specifically at the role country and region of origin of products plays in explaining the relationship. Given the personal nature that attracts people to social media to build relationships, it is believed that the personal nature of brands originating from the social media users’ home country will heighten the likelihood that consumers track certain brands and may enhance the relationship that evolves between the brand and the consumer. A model …


Persecuting Alex Rodriguez: Race, Money And The Ethics Of Reporting The Performance-Enhancing Drug Scandal, Bonnie Brennen, Rick Brown Jan 2014

Persecuting Alex Rodriguez: Race, Money And The Ethics Of Reporting The Performance-Enhancing Drug Scandal, Bonnie Brennen, Rick Brown

College of Communication Faculty Research and Publications

This qualitative textual analysis considers the US press coverage of Alex Rodriguez for his alleged use of performance-enhancing drugs. It evaluates nearly 500 newspaper, magazine and broadcast reports from 2007 to 2014 on Rodriguez, as well as reader and journalistic responses, and finds issues of overt and inferential racism, stereotyping and symbolic impurity, and a crude emphasis on money in the coverage. This research considers the ethics of the press coverage through a framework of Critical Race Theory and suggests an approach rooted in communitarian ethics to foster greater social justice and balance in sports media coverage.


Professionalising Organisational Communication Discourses, Materialities, And Trends, Jeremy P. Fyke Jan 2014

Professionalising Organisational Communication Discourses, Materialities, And Trends, Jeremy P. Fyke

College of Communication Faculty Research and Publications

No abstract provided.


The Importance Of Academic Deans' Interpersonal/Negotiating Skills As Leaders, Shelley B. Wepner, Bill Henk, Virginia Clark Johnson, Sharon Lovell Jan 2014

The Importance Of Academic Deans' Interpersonal/Negotiating Skills As Leaders, Shelley B. Wepner, Bill Henk, Virginia Clark Johnson, Sharon Lovell

College of Education Faculty Research and Publications

Four academic deans investigated when and how they used interpersonal/negotiating skills to function effectively in their positions. For two full weeks, the deans coded their on-the-job interactions during scheduled meetings, informal meetings, spontaneous encounters/meetings, telephone calls, and select email. Analyses revealed that the interpersonal/negotiating skills used, from most to least prevalent, were: working closely with others, being responsive to key persons, negotiating key players' roles, and keeping key persons in the organisation informed. Across these engagements, the deans interacted with 35 different categories of stakeholders inside and outside their institutions for 32 different purposes. Given the nature and range of …


It's Not The Serve, But The Return, Marnee J. Dupont Jan 2014

It's Not The Serve, But The Return, Marnee J. Dupont

Honors Theses and Capstones

No abstract provided.


Smart Phone Purchasing Habits Among The University Of New Hampshire Students, Alexa Lomonaco Jan 2014

Smart Phone Purchasing Habits Among The University Of New Hampshire Students, Alexa Lomonaco

Honors Theses and Capstones

College students are more connected to technology now than ever, especially because a smart phone that has all of the capabilities of a computer is right in their pockets. This study delves into why students at the University of New Hampshire purchase their smart phones, how they use their smart phones, and how to better market toward profitable segments. The two segments found were the technology buffs, who are smart phone experts and are constantly on their devices, and the practical users who mainly use their smart phones for texting and calling. The results from the study showed that students …


Bioremediation Of Hydrocarbons Via Geobacillus, Amanda T. Lade Jan 2014

Bioremediation Of Hydrocarbons Via Geobacillus, Amanda T. Lade

Honors Theses and Capstones

Hydrocarbon remediation is a vital aspect of environmental cleanup, especially in soil and groundwater to ensure the health and safety of the public’s drinking water. A possible solution to this contamination is bioremediation, the use of microorganisms to degrade pollutants. This research analyzes the effectiveness of Geobacillus as a hydrocarbon degrader for the use of bioremediation. Twelve strains were identified from oil-contaminated sources and grown in minimal media with crude oil as the carbon source. Growth was observed in the crude oil samples, demonstrating the possibility of bioremediation of hydrocarbons via Geobacillus.


Pcaob Inspections And Market Repercussions; Is There A Relationship?, Casey J. Wade Jan 2014

Pcaob Inspections And Market Repercussions; Is There A Relationship?, Casey J. Wade

Honors Theses and Capstones

This study tests whether the PCAOB achieves its goals of issuing inspection reports that provide meaningful and value-adding information for external investment decisions, as measured by investor reaction. The study measures informative value by examining cumulative abnormal stock returns of all companies that had an auditor inspected in 2012. Also tested was 'Big Four' versus other annually inspected firms, as well as 12 significant industries. This study provides statistical evidence that investors respond to PCAOB inspection reports, the responses of which are typically positive. These results demonstrate that investors recognize inspection reports as value-relevant, and consquently use them to make …


Developing Genetic Tools For Geobacillus, Brittany Artale Jan 2014

Developing Genetic Tools For Geobacillus, Brittany Artale

Honors Theses and Capstones

Bacillus and Geobacillus are the primary bacterium used in biotechnology industries due to their ability to excrete extracellular materials such as proteins, enzymes and other byproducts. Bacillus subtilis, has a well-characterized competence machinery, giving way to characterized genetic tools. However, a significant problem associated with working with Bacillus is the regulation of endospore formation. An alternative to Bacillus is Geobacillus, a thermophilic bacterium. Thermophiles offer significant advantages over other bacteria as host organisms in biofuel, bioremediation, and biocatalyst processes. However, the genetic tools and competency associated with Geobacillus is still unknown. Through, genetic engineering the ability …


Instilling Diet And Exercise Confidence: Influence Of Nurse Body Size, Erin Murdock Spaulding Jan 2014

Instilling Diet And Exercise Confidence: Influence Of Nurse Body Size, Erin Murdock Spaulding

Honors Theses and Capstones

This paper reports a research study focused on perspective of nurse body size and how it affects confidence in a nurses’ ability to provide education on diet and exercise. The study followed a descriptive method design guided by a cross-sectional survey with quantitative variables. Results show that there is increased confidence in a nurse’s ability to provide education and influence habits regarding diet and exercise when the nurse role models such behaviors. Other findings presented include respondents’ perception of their body mass index versus their actual body mass index, percentage of respondents with health care conditions related to obesity, and …


Wicked Intense: The Grammaticalization Of Wicked And Other Intensifiers In New Hampshire, Emma M. Brown Jan 2014

Wicked Intense: The Grammaticalization Of Wicked And Other Intensifiers In New Hampshire, Emma M. Brown

Honors Theses and Capstones

This article presents a synchronic study of wicked and other intensifiers in Southern New Hampshire. Two sets of data were collected: one from the social media website Twitter, and the other from spoken casual interviews conducted by students at the University of New Hampshire. In all, more than 9000 intensifiable adjectives and verbs were collected, with rates of 22 and 24 per cent intensification for the Twitter and spoken data, respectively. The first goal of this paper is to show that one intensifier in particular, wicked, is in the process of grammaticalizing through the mechanisms of desemanticization and extension …


Segregation In United States Healthcare: From Reconstruction To Deluxe Jim Crow, Kerri L. Hunkele Jan 2014

Segregation In United States Healthcare: From Reconstruction To Deluxe Jim Crow, Kerri L. Hunkele

Honors Theses and Capstones

During the time period between Reconstruction and the Deluxe Jim Crow era, African Americans were legally oppressed, which hindered their ability to live fully and equally in society with whites. This was especially true in terms of healthcare. Segregation laws were implemented to separate blacks from the rest of society in everyday life; the worst of these laws affected the ability of African Americans to gain access to medical care that was equal to whites. This inequality prevented blacks from being accepted into society and from living quality lives that stem from adequate healthcare. Although the federal and state governments …


Alienation In Capitalism: Rediscovering Fulfillment, Gregory Lee Carter Jan 2014

Alienation In Capitalism: Rediscovering Fulfillment, Gregory Lee Carter

Honors Theses and Capstones

Many Americans are pessimistic about their country's medium or long-term economic outlook. A century ago, Big Business was born as an economic force, but it has powerfully infiltrated the realm of politics now. The corporate scramble for natural resources has caused global disharmony and domestic economic conflict in the U.S. The capitalist system, which many have come to realize is unsustainable and oppressive, has thus come to fulfill some of the predictions made by earlier critics from Kierkegaard, Rousseau, to Marx. Each believed that a society which is forced to accommodate an oppressive system will inherently display alienation. That …


Assessing The Fishery And Ecology Of Sharks In The United Arab Emirates, Rima W. Jabado Jan 2014

Assessing The Fishery And Ecology Of Sharks In The United Arab Emirates, Rima W. Jabado

Dissertations

Large scale shark population declines have been documented worldwide due to overexploitation and the lack of adequate management frameworks to conserve shark stocks. This study aimed at gaining an understanding of the national shark fishery and the trade in shark products from the United Arab Emirates (UAE). Data were collected from June 2010 to October 2012 through interviews with local fishermen, market and landing site surveys, fishery independent surveys, and stomach content analysis. Interviews with local fishermen (n=126) provided information on the fishery characteristics and established that sharks were increasingly targeted due to their high value in the global fin …


The "Globesity" Trend: Exploring The Ethical Concerns Of Registered Nurses Caring For Bariatric Surgery Patients, Casey L. Lowden-Crook Jan 2014

The "Globesity" Trend: Exploring The Ethical Concerns Of Registered Nurses Caring For Bariatric Surgery Patients, Casey L. Lowden-Crook

Theses

Obesity is a major global health problem. The comorbidities associated with obesity (for example: diabetes mellitus type 2 and cardiovascular disease) are multisystem and require continual medical management which places a great strain on the healthcare system. Australia is ranked the 5th most obese population in the world and deaths associated with obesity and obesity related illnesses are estimated at 7,200 per year (Medibank, 2010). This lifestyle disease is now the leading cause of premature death in Australia. The obesity epidemic is blamed on changes in the social, economic and physical environment (obesogenic environments) which have influenced people to over-consume …


Negotiating Crisis In The Social Media Environment: Evolution Of Crises Online, Gaining Credibility Offline, A. Pang, Nasrath Begam Binte Abul Hassan, Aaron Chee Yang Chong Jan 2014

Negotiating Crisis In The Social Media Environment: Evolution Of Crises Online, Gaining Credibility Offline, A. Pang, Nasrath Begam Binte Abul Hassan, Aaron Chee Yang Chong

Research Collection Lee Kong Chian School Of Business

Purpose– The aim of this paper is to examine how crises can be triggered online, how different social media tools escalate crises, and how issues gain credibility when they transit to mainstream media.Design/methodology/approach– This exploratory study uses the multiple case study method to analyze five crises, generated online, throughout their life-cycles, in order to build analytic generalizations (Yin).Findings– Crises are often triggered online when stakeholders are empowered by social media platforms to air their grievances. YouTube and Twitter have been used to raise issues through its large user base and the lack of gatekeeping. Facebook and blogs escalate crises beyond …