Digital Commons Network^™

Dystonia Type 6 Gene Product Thap1: Identification Of A 50 Kda Dna-Binding Species In Neuronal Nuclear Fractions, Maitane Ortiz-Virumbrales, Marta Ruiz, Eugene Hone, Georgia Dolios, Rong Wang, Andrika Morant, Jessica Kottwitz, Laurie J. Ozelius, Sam Gandy, Michelle Ehrlich

Research outputs 2014 to 2021

Mutations in THAP1 result in dystonia type 6, with partial penetrance and variable phenotype. The goal of this study was to examine the nature and expression pattern of the protein product(s) of the Thap1 transcription factor (DYT6 gene) in mouse neurons, and to study the regional and developmental distribution, and subcellular localization of Thap1 protein. The goal was accomplished via overexpression and knock-down of Thap1 in the HEK293T cell line and in mouse striatal primary cultures and western blotting of embryonic Thap1-null tissue. The endogenous and transduced Thap1 isoforms were characterized using three different commercially available anti-Thap1 antibodies and validated …

Disease Interpretations And Response Among Hiv-Positive Mothers, Johanna Debora Imelda

Antropologi Indonesia

Despite the growing number of new cases of HIV and AIDS in Indonesia, the progress of prevention programs has been slow. Low prevelance is always stated as a reason for delaying HIV prevention programs and to justify slow progress in implementation. Prevention programs are moreover based on a high-risk group paradigm. They focus on female sex workers as responsible for the spread of HIV, leading to its stigmatization as a hooker's disease. This article describes how seropositive mothers interpret and respond to HIV and AIDS as women, in light of the fact that most of them have not experienced full-blown …

Orang Kulisusu, Identitas Dan Kekuasaan: Reproduksi Identitas Kultural Dalam Proses Pemekaran Kabupaten Buton Utara, Nurlin -

Antropologi Indonesia

This article describes the relationship between power, history and identity in the processof division North Buton of Muna. In this article the presence of North Buton identity is seen asa phenomenon that refers to the identity of reproduction historical narrative where Kulisusuin historical context has a power relationship with the kingdom of Buton which lasted fromthe 17th century. This study found; that the presence of North Buton identity is a product ofdiscourse that legitimized by indigenous groups who identify themselves as descendants ofthe founder of the kingdom Kulisusu. it means that the identity of North Buton formed dueto higher power …

Effect Of Magnetic Nanoparticle Heating On Cortical Neuron Viability, Christopher J. Rivet, Yuan Yuan, Ryan J. Gilbert, Diana Andra Borca-Tasciuc

Chemical and Biochemical Engineering Faculty Research & Creative Works

Purpose: Superparamagnetic iron oxide nanoparticles are currently approved for use as an adjunctive treatment to glioblastoma multiforme radiotherapy. Radio frequency stimulation of the nanoparticles generates localized hyperthermia, which sensitizes the tumor to the effects of radiotherapy. Clinical trials reported thus far are promising, with an increase in patient survival rate; however, what are left unaddressed are the implications of this technology on the surrounding healthy tissue. Methods and materials: Amino silane-coated iron oxide nanoparticles suspended in culture medium were applied to chick embryonic cortical neuron cultures. Cultures were heated to 37 °C or 45 °C by an induction coil system …

Impact Of Loss Synchronization On Reliable High Speed Networks: A Model Based Simulation, Suman Kumar, Lin Xue, Seung Jong Park

Computer Science Faculty Research & Creative Works

Contemporary nature of network evolution demands for simulation models which are flexible, scalable, and easily implementable. In this paper, we propose a fluid-based model for performance analysis of reliable high-speed networks. In particular, this paper aims to study the dynamic relationship between congestion control algorithms and queue management schemes, in order to develop a better understanding of the causal linkages between the two. We propose a loss synchronization module which is user configurable. We validate our model through simulations under controlled settings. Also, we present a performance analysis to provide insights into two important issues concerning 10 Gbps high speed …

Asia Pacific Perspectives Vol. 12 No. 2, Spring/Summer 2014, University Of San Francisco

Asia Pacific Perspectives

Contents:

What's in a Game? Transmedia Storytelling and the Web-Game Genre of Online Chinese Popular Fiction by Heather Inwood

This paper uses a genre of online Chinese popular fiction known as Web-Game fiction as an entry point for exploring the influence of Massively Multiplayer Online Role Playing Games (MMORPGs) on linear narrative fiction. By offering a thick description of MMORPG gameplay and of gamers’ movements between online and offline worlds, Web-Game fiction narrates and “deinteractivates” the subjective experiences of players as they progress through the levels of online role-playing games. This essay proposes that the genre offers an alternative perspective …

School Violence Perpetrators Speak: An Examination Of Perpetrators Views On School Violence Incidents, Gordon A. Crews

Criminal Justice Faculty Publications

In the last few decades researchers have attempted to determine correlates for school violence. While the number of extreme incidents of school violence remains relatively small, extreme incidents cause the most concern for parents, teachers, law enforcement, and educational administrators. In addition to the fear these types of events cause, they also bring about a great deal of debate regarding proper responses. Some feel that stringent zero tolerance policies are the answer, while others argue for more gun control in society. Some feel that increased counseling and service to young people is the answer, while others argue for the increased …

Tickling The Palate: Gastronomy In Irish Literature And Culture, Máirtín Mac Con Iomaire, Eamon Maher

Books

This volume of essays, which originated in the inaugural Dublin Gastronomy Symposium held in the Dublin Institute of Technology in June 2012, offers fascinating insights into the significant role played by gastronomy in Irish literature and culture. The book opens with an exploration of food in literature, covering figures as varied as Maria Edgeworth, James Joyce, Charles Dickens, Enid Blyton, John McGahern and Sebastian Barry. Other chapters examine culinary practices among the Dublin working classes in the 1950s, offering a stark contrast to the haute cuisine served in the iconic Jammet's Restaurant; new trends among Ireland's 'foodie' generation; and the …

Snakes And Ladders: Suo Moto Intervention And The Indian Judiciary, Marc Galanter

FIU Law Review

No abstract provided.

Don’T Be A Drag, Just Be A Queen—How Drag Queens Protect Their Intellectual Property Without Law, Eden Sarid

FIU Law Review

No abstract provided.

The Tower Of David: Social Order In A Vertical Community, Manuel A. Gómez

FIU Law Review

No abstract provided.

A Fundamentally Different Regulatory Calculus: The Advent Of Regulation D, Rule 506(C), Ashley J. Hersutamto

FIU Law Review

No abstract provided.

Exploiting Fluencies: Educational Expropriation Of Social Networking Site Consumer Training, Lucinda Rush, Dylan E. Wittkower

Libraries Faculty & Staff Publications

The idea of the digital native was based on abstraction; when we look in detail at the digital activities of high-school and college students, we see deskilling and consumer training rather than information literacy or technical fluency. Yet that training is still training, and may be adaptable in such a way that it can become a literacy—in, for example, the way militaries have mobilised skill-sets produced through gaming. We too can and should mine the narrow and profit-driven consumer training that emerging adults have undergone for kinds of inquiry and critical engagement for which they may have inadvertently been given …

Research Thesis Essay Of Findings From Campus Language Capacity Survey 2012-2014 Done In Collaboration With The Heritage Language Initiative, Laura Van Doren

University Honors Theses

This paper presents the findings of the Campus Language Capacity Survey 2013, a study conducted as an online survey to investigate heritage language usage at Portland State University. Heritage language is defined as “an indigenous or immigrant language other than English.” The survey was sent to 15,000 randomly selected participants from the PSU student, staff, and faculty body; over 1,000 responses were collected. There was a 10% response rate with 119 participants self-identified as heritage language speakers and/or learners. These participants are individuals in the PSU community who have ties to their heritage community. The top five heritage languages named …

Activist Investors, Distressed Companies, And Value Uncertainty, Michelle M. Harner, Jamie Marincic Griffin, Jennifer Ivey-Crickenberger

Faculty Scholarship

Hedge funds, private equity firms, and other alternative investment funds are frequently key players in corporate restructurings. Most commentators agree that the presence of a fund can change the dynamics of a chapter 11 case. They cannot agree, however, on the impact of this change—i.e., do funds create or destroy enterprise value? This essay contributes to the dialogue by analyzing data from chapter 11 cases in which funds are in a position to influence the debtor’s exit strategy. The data shed light on what such funds might achieve in chapter 11 cases and the potential implications for debtors and their …

Ignatian Pedagogy And Its Alignment With The New Teacher Bar Exam (Edtpa) And Action Research Frameworks, Suzann Girtz

Jesuit Higher Education: A Journal

Teacher Preparation Programs are subject to increasing demands on their curriculums, with no corresponding increases in contact time or duration of programs. As new high-stakes pre-service teacher assessments come online, programs must prepare candidates for success with them while still honoring other elements, such as research in accelerated graduate programs and university identities through specialized pedagogies. Programs face the challenge of teaching it all, and doing so in a coherent manner. This article addresses the alignment across components of edTPA (pre-service education Teacher Performance Assessment), action research, and Ignatian pedagogy, providing a table that aligns the three frameworks.

Mission, Religion, Religious Studies? Student Perspectives On Courses In Buddhism And Islam At A Jesuit University, Bret Lewis

Jesuit Higher Education: A Journal

In the Fall Semester of 2013, at Loyola University Chicago (LUC), a total of 140 students enrolled in select sections of either Theo 295: Introduction to Islam or Theo 297: Introduction to Buddhism. These students, seeking to fulfill core theology requirements through religious studies courses, were surveyed before and after the semester in an attempt to measure attitudes, and potential changes in attitude, about religion and the study of religion – and how these may connect to the context of Jesuit education. This paper attempts to uncover the relationship between the Jesuit theological underpinnings referenced in the mission statement and …

Accompanying The Student: The Ignatian Pedagogical Paradigm And Prior Learning, Kimberly R. Connor

Jesuit Higher Education: A Journal

At the University of San Francisco’s School of Management (SoM), working adults enrolled in our Bachelor of Science in Management degree completion program participate in a process of experience and reflection that prepares them, as our slogan proclaims, to “change the world from here.” Before our working adult students take a management or business class, they are introduced to a process we call the Interdisciplinary Studies Assessment (ISA), a prior learning opportunity that is distinctive for how it works within an Ignatian Pedagogical Paradigm (IPP) that recognizes that learning is a lifelong journey that can take place in a variety …

Deal Deconstructions, Case Studies, And Case Simulations: Toward Practice Readiness With New Pedagogies In Teaching Business And Transactional Law, Michelle M. Harner, Robert J. Rhee

Faculty Scholarship

In this short commentary, we explore the use of two interrelated pedagogical methods for teaching transactional and business law. The first method is deal deconstruction, which analyzes the set of final deal documents and outcomes. This method is backward-looking, conducting a post-mortem on business transactions and analyzing the parties’ choices memorialized in the agreement against the legal and financial alternatives. The second method involves case studies and simulations, which are commonly seen in business schools. This method is forward-looking, exposing students to the uncertainties and situational contexts of doing deals and deal-related litigation. Together, these complementary methods help students understand …

Influence Of Social Class Perceptions On Attributions Among Mental Health Practitioners, Mindi Thompson, Jacob Diestelmann, Odessa Cole, Abiola O. Keller, Takuya Minami

Physician Assistant Studies Faculty Research and Publications

Objective: A vignette-based study assessed the influence of social class attributions toward a hypothetical client's difficulty. Method: 188 licensed mental health professionals who were recruited through professional listservs completed an online survey after reviewing one of two versions of a vignette describing a hypothetical client that varied based on social class cues. Results: As expected, this sample of licensed mental health practitioners detected social class differences based on the descriptors of the hypothetical client across the two vignettes. These perceived social class differences, however, did not impact participants' attributions toward the client for causing or solving her problems, level of …

The Influence Of Patient Activation And Social Facilitation On Engagement In Postpartum Weight Self-Management Behaviors, Jennifer Marie Ohlendorf

Dissertations (1934 -)

Aims: To explore factors that influence the process of women's engagement in postpartum weight self-management (PPWSM) behaviors (eating and physical activity). Transitions Theory and the Integrated Theory of Health Behavior Change guided the selection of salient variables including transition conditions, level of patient activation, and social facilitation, to be examined for association with PPWSM behaviors.

Background: Women who do not lose their pregnancy weight are at higher risk of being overweight or obese later in life. Little is known about what women do to self-manage the return to pre-pregnant weight and how providers can influence PPWSM.

Design: Prospective, longitudinal, correlational …

The Role Of Civil Society In Environmental Governance In The United States And China, Robert V. Percival, Zhao Huiyu

Faculty Scholarship

No abstract provided.

Facilitating Successful Failures, Michelle M. Harner, Jamie Marincic Griffin

Faculty Scholarship

Approximately 80,000 businesses fail each year in the United States. This article presents an original empirical study of over 400 business restructuring professionals focused on a critical, arguably contributing factor to these failures—the conduct of boards of directors and management. Anecdotal evidence suggests that management of distressed companies often bury their heads in the sand until it is too late to remedy the companies’ problems, a phenomenon commonly called “ostrich syndrome.” The data confirm this behavior, show a prevalent use of loss framing, and suggest trends consistent with prospect theory. The article draws on these data and behavioral economics to …

Educational Programmes For Spatial Information Sciences In The Technological University Of Dublin, William Prendergast, Eamonn Murphy, Audrey Martin, Avril Behan

Conference papers

The ever increasing spatial information needs of society, the rapid development of new surveying technologies, and the global demand for appropriately qualified surveyors, have triggered a radical re-evaluation of geomatics education worldwide. Significant enhancements have been made to the educational programmes in the spatial information science discipline in the Technological University of Dublin’s (DIT) during the last decade including the provision of a BSc in Geomatics and various masters’ programmes to cater for the increasingly specialised needs of the Geographic Information sector in Ireland.

An Exploration Into The Potential Of Irish Films (1896-1962) For Empathic Approaches To The History Classroom, Thomas Mcgraw Lewis

Doctoral

This thesis applies historical empathy as a lens through which Ireland’s filmic heritage can be explored within the teaching of history. In its approach, the research asserts that critical perspective recognition and affective exploration can be achieved through a sustained model of historical narrative inquiry. Undertaking textual analysis of a series of pre-televisual films from the National Film Archive, it argues that there is value in these records for understanding the formulation and assessment of political and social representation in the nascent Republic. While remaining cognizant of the constraints placed on both the educational and archival professions in Ireland, the …

Industrial Relations And The Construction Sector: The Implications Of Mcgowan And Ors V The Labour Court, Ruairi Hayden

Other Resources

On the 9^th May 2013 the Supreme Court in McGowan and Ors v The Labour Court and Ors found Registered Employment Agreements to be incompatible with the Constitution. Registered Employment Agreements (REA) are provided for in Part III of the Industrial Relations Act 1946. Collective bargaining has traditionally been the method for employees and employers to negotiate terms of employment within the construction industry. These agreements would then be registered with the Labour Court and they would have legal effect. Registered Employment Agreements are particularly suited to the construction industry due to the labour intensive nature of the industry …

Concern-Driven Integrated Toxicity Testing Strategies For Nanomaterials - Report Of The Nanosafety Cluster Working Group 10, Hugh Byrne, Agnes G. Oomen, Peter M.J. Bos, Teresa F. Fernandes, Kerstin Hund-Rinke, Diana Boraschi, Karin Aschberger, Stefania Gottardo, Frank Von Der Kammer, Dana Kühnel, Danail Hristozov, Antonio Marcomini, Lucia Migliore

Articles

Bringing together topic-related European Union-(EU)-funded projects, the so-called “NanoSafety Cluster” aims at identifying key areas for further research on risk assessment procedures for nanomaterials (NM). The outcome of NanoSafety Cluster Working Group 10, this commentary presents a vision for concern-driven integrated approaches for the (eco-)toxicological testing and assessment (IATA) of NM. Such approaches should start out by determining concerns, i.e. specific information needs for a given NM based on realistic exposure scenarios. Recognized concerns can be addressed in a set of tiers using standardized protocols for NM preparation and testing. Tier 1 includes determining physico-chemical properties, non-testing (e.g. structure …

Words Worth Price And Value, Tom Dunne

Articles

TOM DUNNE explains the terms used in relation to the valuation of property, and the need for common understanding among all parties using those terms. -

Locative Histories: Exploring The Continued Influence Of Early Locative Media Art, Conor Mcgarrigle

Articles

This paper, which draws on aspects of my doctoral research, traces the influence of early Locative Media Art on the current form and application of location-aware technologies. The mechanisms and impulse for this influence are introduced and analyzed and it is proposed that they point to new approaches in the consideration of the agency of Locative Media art.

I return to the origins of Locative Media at the Karosta workshop and the ambitions of early practitioners to argue that the practice was based on a prescient analysis of the potential for ubiquitous networked location-awareness. From this analysis was developed an …

Spatial Moment Analysis Of Reactive And Radioactive Solute In River System With Layered Porous Bed, Shadab Anwar

Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works

Mass exchange between river stream and riverbed is critical towards remediation of contaminated river system. Spatial moment analysis of reactive and radioactive solute in river channel with underlying porous bed is applied to understand the qualitative description of solute plume in riverbed and river stream. Semi-analytical solutions for zeroth-, first- and second-order spatial moment of reactive and radioactive solute are derived in Laplace domain. The spatial moments of concentration are numerically inverted. Parabolic velocity in river channel and exponentially decaying velocity in porous bed are linked using a slip velocity at the interface. The model is verified against the semi-analytical …