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Investigation Of Pharmaceutical Mass Transfer Phenomena Using Molecular Dynamics Simulations, Yi Gao

Dissertations

Molecular dynamics (MD) simulation has been widely used in understanding the physical basis of the structure and function of biological macromolecules. However, its application in pharmaceutical research is still at an early stage. This dissertation attempts to establish the use of MD simulation in studying several important pharmaceutical mass transfer processes. The three-series study included (1) the understanding of drug crystal dissolution at molecular level, (2) the elucidation of an unique mechanism for facile polymorphic transformation of crystalline drugs in solutions, and (3) the determination of drug-polymer interactions at water-crystal interface and the implications to crystallization inhibition.

A drug crystal …

Identification And Analysis Of Omentum Derived Suppressor Cells In Regards To Th17 Inhibition, Nick Huang

Dissertations

Omentum has been harnessed by surgeons for hundreds of years, providing an ideal environment for graft healing and acceptance. However, little is known about the cellular mechanisms that promote the tolergenic environment of the omentum. We examined the cellular composition and role of activated omentum in regards to T-cell immunomodulation. We then tested activated omentum as a cellular therapy in a mouse allogenic lung transplantation model.

Our findings demonstrated activated omentum is mostly comprised of non-hematopoietic cells resembling mesenchymal stem-like cells (MSCs) and myeloid derived suppressor cells (MDSCs). Activated omentum exhibited anti-inflammatory properties through suppression of Th1 and Th17, while …

There's A Place For Us: How Ethnic Identities Are Revealed In Ethnic-Specific Organizations, Crystal Jackson

Dissertations

Ethnic-specific organizations have long been features of American society. Historically, they have provided ethnic actors with

a means of preserving culture and history. They have also been sites where collective interests are pursued. In this dissertation I study two ethnic-specific organizations. Using identity, incorporation and

inequality, as essential dimensions of American ethnicity, I describe how the political and civic work that occurs in two organizations reveals

group boundaries.

My data and analysis support three major findings. First, I find

that the identities that emerge from this kind of organizational work are transactional identities. Transactional identities are identities that are confirmed …

Toward The Development Of Roman Catholic Teaching About Contraception In Light Of The Experience Of South Korean Catholic Women, Taeeun Kim

Dissertations

In recent decades, the morality of artificial contraception has been hotly debated in the Roman Catholic Church. Many theologians and ethicists have challenged the hierarchical church teachings in the last fifty years. The opening chapter of the dissertation reviews Catholic Church teachings on birth control throughout history, and in Chapter Two I explore the theo-ethical reflections on artificial contraception from two different approaches (traditionalist and revisionist) and support the revisionists' perspectives, findings, and arguments. Then, in order to lay the context for my interpretations of my ethnographic interviews with ten participants, in Chapter Three I explore South Korean sexual culture …

Pirates Of Romanticism: Intellectual Property Ideology And The Birth Of British Romanticism, Jason Isaac Kolkey

Dissertations

This dissertation traces the role of unauthorized publication in the posthumous construction of British Romanticism as a literary movement. It argues that Romantic ideology emerged from conflicting claims about the nature of intellectual property and the circulation of political and artistic ideas, apparent in the texts and paratexts of pirated books. I examine how these disputes play out in reprints of the works by Percy Bysshe Shelley and Robert Southey that became cornerstones of radical culture. The dissertation goes on to discuss how the underground economy of literary piracy affected Sir Walter Scott and Lord Byron's publication strategies, the significance …

He Seems Like A Good Kid Lessons In Informal Social Control From A Midwestern Peer Court Program, Patricia Lee Maddox

Dissertations

This study examines how peer court jurors make meaning out of the sanctioning trials of youth offenders. In particular, it focuses on how peer court jurors understand juvenile delinquency, deterrence and punishment. Data was collected utilizing ethnographic field observation methods while attending a Midwestern County's peer court program between the end of the 2011-2012 school year and the 2012-2013 school year. Thirteen interviews were conducted after the sessions with willing peer court jurors in order to supplement the field work data.

During the peer court sessions the youth jurors tried to understand the nature of the offenses and how to …

Master's Students' Experiences In A Graduate Preparation Program: Multicultural Competency And Social Justice Curriculum, Kristin I. Mccann

Dissertations

This dissertation study focused on master's students experiences with multicultural competency curriculum in graduate preparation programs (GPPs) and contributes to gaps in the extant literature on multicultural issues in higher education. The two overarching research questions for the study considered how, if at all, students' understanding of core concepts of the required course (privilege, oppression, and social justice) changed over time as evidenced by a primary curricular component called the photo elicitation project. Educators' experiences were also addressed, per their impact on the context in which students learned. This study employed a qualitative approach and, in line with the study's …

Internalization Of Race Messages Among Mixed Race Individuals, Jennifer Moulton

Dissertations

The present study used grounded theory qualitative methodology to explore mixed race individuals' experiences within specific racial socialization contexts of family, friends, community, and society, to identify messages received within these contexts. How messages influence both their understandings of mixed race identity and how they racially identify themselves was also examined. Mixed race identity development was found to follow an ecological framework, in which racial socialization messages serve as a mechanism through which experiences within contexts may be interpreted, to then inform conceptions of racial identity and identification choices. Common themes of experiences emerged within contexts, including disownments/disapproval, sibling differences, …

The Ethics Of Vision And Black Theology And Experience, Angelo Sylvester Riley

Dissertations

To this day, philosophical ethics and dominant discussions in Christian ethics have paid insufficient attention to how vision shapes the moral life. Too much focus is given to moral decision-making and action, while too little focus is given to the way vision and patterns of attentiveness ground our capacities for genuine morally responsible action. Therefore, in this study, I draw on important works in philosophical and Christian ethics to examine both the ethics of responsibility and the central role that an ethics of vision plays in our attempts to live responsibly. I use the "ethics of vision" as method and …

When Subcultures Become Careers: Working In Indie Rock, Annmarie Schneider-Edman Van Altena

Dissertations

This dissertation examines the careers of workers within the Indie rock industry in Chicago. Little is known about how workers transition from subculture participants to industry workers. Expanding upon research on workers in culture industries, I conducted twenty-six qualitative interviews with workers in the industry, asking open-ended questions about their careers and experiences to understand how they establish and maintain careers in an industry that relies on a particular subculture whose ethos considers financial success as suspect, and a risk to integrity. I show how workers' early interest in music goes beyond typical teenage fascination and becomes the focus of …

Neuroscience And Galen: Body, Selfhood And The Materiality Of Emotions On The Early Modern Stage, Devon Wallace

Dissertations

From antiquity until the turn of the nineteenth century, temperament, mood and personality were believed to exist within, be managed by, and interact with material substance. Before the medical revolution of the late seventeenth century, early modern theories of anatomy and medicine were primarily based on the writings of Galen, who lived in the second century but was him influenced by a much older medical and philosophical tradition. In this period, the playwrights raise the same central question that now appears in so many reactions to the increasingly accepted "neurocentric" world view: "to what extent do I have an emotional …

The Moroccan Example: “Coming Movements,” Communities, And Lived Experience In Contemporary Protest, Paige I. Ambord

Senior Independent Study Theses

What is the legacy of the Arab Spring, Occupy Wall Street, and associated protests? This is the question at the heart of this paper. To answer it, I will argue that these protests are indicative of an international mobilization that together shared both a horizontal structure and pseudo-utopian philosophy, which, in turn, affected how activists understood their own movements. To begin, this paper traces the precursors of these horizontal protests within the literature, analyzing their origins in events such as the World Trade Organization protests in Seattle (1999) and the World Social Forums since then. Next, I use Giorgio Agamben’s …

Rocky Shores: From Habitat Threat To Marine Awareness & Well-Being Benefits, Kayleigh Wyles

School of Psychology Theses

Previous psychological research has demonstrated the benefits of visiting natural environments, especially coastal areas. However, research within Marine Biology has shown that such visits can harm natural habitats. Consequently, this thesis uses an integrative approach to examine both the risks to the environment and benefits to the human visitors in the context of rocky shores (intertidal areas where solid rock predominates). This was investigated using seven studies that involved a range of methods. Perception-based surveys (Studies 1 & 2) explored the perceived impacts on the visitor, and the potential impacts these visits can have on the rocky shore. Study 3 …

The Youth Unemployment Crisis Facing Welfare Regimes: How States Develop New Social Policy, Andrew C. Campbell

Senior Independent Study Theses

No abstract provided.

Rising From The Ashes: Hansen’S Disease, Carville, And Patient Identity In 20th Century America, Lauren Quimby

Senior Independent Study Theses

This paper investigates the reactions of patients in the national leprosarium at Carville, Louisiana to the loss of their old identities and the gain of a new one as a patient during the middle of the 20^th century. The patient identity was formed by isolation, stigma, community, and domesticity within the hospital. Over the course of their time in the hospital, residents rejected, embraced and worked to change the patient identity. They typically reacted in a combination of these ways. This paper uses memoirs, oral histories, and patient published newspapers to investigate questions of patient identity at Carville. The …

Dueling For Their Votes: A Study On The Impact Of Presidential Debate Rhetoric On Public Opinion, Daniel J. Cohen

Senior Independent Study Theses

The debates are key events for presidential candidates to influence public support for their policies. This study examines the impact of rhetorical strategies during presidential debates on public perceptions of unpopular issue stances. Using generic criticism, I examined the first two 2012 debates between Barack Obama and Mitt Romney and uncovered four rhetorical strategies used by the candidates: issue framing, appeals to authority, use of rebuttals, and appealing to liberal and conservative presumptions. I then tested an example of issue framing from each candidate to determine its effectiveness in persuading public opinion on unpopular issue stances. My results showed that …

Norms And Varieties Of English And Tesol Teacher Agency, M. Obaidul Hamid, Lingyan Zhu, Richard B. Baldauf Jr.

Australian Journal of Teacher Education

The growing recognition of the plurality of English underling the World Englishes (WE) paradigm has problematised the conventional second language acquisition (SLA) views of errors. If English use in emerging English-speaking contexts is to be judged by local norms, as argued by WE scholars, applying exocentric norms in these contexts can be inappropriate. On the other hand, despite the significant growth of WE, varieties of new Englishes have yet to develop widely acceptable endocentric norms. These developments have raised a critical question: How can TESOL teachers distinguish between errors in the SLA sense and varietal features in the WE sense? …

Western Australian Music Teachers And The Wace Music Syllabus Five Years Down The Track: Where Are We Now?, Geoffrey M. Lowe, Andrew Sutherland

Australian Journal of Teacher Education

Western Australia introduced a new Western Australian Certificate of Education (WACE) Music course for Year 11 and 12 students in 2009. The construction of the course was protracted due to political interference at the ministerial level, input from vested interests within the music teaching community and adverse publicity in the wider community. The result has been the creation of a long and potentially confusing syllabus document. This paper reports on music teacher experiences with the WACE music course five years after its initial implementation. A questionnaire was distributed to all WACE music teachers asking them to respond to 27 statements …

The Literacy Skills Of Secondary Teaching Undergraduates: Results Of Diagnostic Testing And A Discussion Of Findings, Brian Moon

Australian Journal of Teacher Education

Abstract: The capacity of secondary school teachers to support general literacy and to teach discipline-specific literacy skills depends upon their personal literacy competence. Diagnostic testing of 203 secondary teaching undergraduates at one Australian university revealed deficiencies in personal literacy competence that could affect their future teaching effectiveness. The sample of undergraduates was tested in spelling, vocabulary, and punctuation. Analysis of the results showed high rates of error on general spelling and vocabulary tasks. The degree of error in many cases was severe. For some undergraduates, the prospect of successful remediation so late in their academic career appeared poor. It is …

Cultural Identity Through Art(S)Making: Pre-Service Teachers Sharing Ideas And Experiences., Jennifer Munday, Atia Sajid, Brandi Reader

Australian Journal of Teacher Education

In their Bachelor degree, Early Childhood Pre-service teachers undertake art(s)making and online journaling (blogging) to chronicle the process and thinking through the problem of them’selves’ in relation to their world. They express and challenge their own thoughts and ideas regarding their daily lives and those of the children in their future classrooms.

The article is presented as a Case Study with the outcomes of the process of the assessment task and the resulting artwork through two student experiences from different cultural backgrounds who produced artworks using different processes and deep reflections about their lives.

The sharing of the reflections through …

Mathematics, English And Gender Issues: Do Teachers Count?, Gilah C. Leder, Helen J. Forgasz, Glenda Jackson

Australian Journal of Teacher Education

Pedestrians were stopped in the street and asked about their views on the teaching and learning of mathematics and English for boys and girls. Many commented on the importance of teachers for both subject areas; some respondents self-identified as teachers. In this article we present findings on the gendering of mathematics and English and the impact that teachers can have on learning outcomes in these disciplines. The data reveal that mathematics is endorsed by many as a male domain and English as a female domain, and that teachers play an influential part in the learning outcomes – achievement, future participation, …

An Exploration Of The Relationship Between Teachers’ Psychological Capital And Their Collective Self-Esteem, Charmaine S. Bissessar

Australian Journal of Teacher Education

Teachers who possess high levels of psychological capital and collective self-esteem are better able to cope with the spate of school violence, student/student bullying, and other current issues confronting the education system globally, regionally, and nationally. A teacher psychological capital high in hope, optimism, self-efficacy, resilience, and collective self-esteem translates into educators who possess a more positive outlook and can impart and influence how their students perceive themselves. No known research exists in the Trinidadian context linking both psychological capital and collective self-esteem. This study expands the body of research in these two areas, locally, by reporting the findings of …

Investigating The Literacy, Numeracy And Ict Demands Of Primary Teacher Education, Helen De Silva Joyce, Susan Feez, Eveline Chan, Stephen Tobias

Australian Journal of Teacher Education

The pre-service programs delivered in Australian teacher education institutions are expected to graduate students who meet externally determined standards, including standards in literacy, numeracy and information and communication technology. These programs are also expected to educate future teachers in professional knowledge and practice, as well as prepare them to engage in professional learning continuously throughout their careers. This paper reports on the first phase of a project that investigated the literacy, numeracy and ICT demands of assessment tasks across the four years of the Bachelor of Education (Primary) program at a regional university.

Wynne: Lose Or Draw, Brannon P. Denning, Norman R. Williams

Vanderbilt Law Review En Banc

No abstract provided.

Comptroller V. Wynne And The Futile Search For Non-Discriminatory State Taxation, Adam B. Thimmesch

Vanderbilt Law Review En Banc

No abstract provided.

Nitric Oxide Inhibitory Activity Of Herbal Extract Formulae For Anti-Inflammation, Intouch Sakpakdeejaroen, Sunita Makchuchit, Arunporn Itharat

Asian Medical Journal and Alternative Medicine

Introduction: The objective of this research was to investigate anti-inflammatory activity of herbal extracts formulaefrom four plants, Zingiber cassumunar (ZC), Centella asiatica (CA), Zingiber officinale (ZO) and Piper nigrum(PN) by variable proportion of each plant. The active compound(s) contributing to its anti-inflammatoryactivity of best formula was verified using high performance liquid chromatography (HPLC) method.

Method: Inhibitory activity against lipopolysaccharide (LPS) induced nitric oxide production in RAW 264.7cell lines was used as assay for anti-inflammation. Each plant and five formulae (CF1-CF5) wereextracted by maceration in 95% ethanol.

Result: The ethanolic extract of CF2 and CF4 showed the highest nitric oxide …

The Four Noble Truths Of Hia And Eia, Pornchai Sithisarankul

Asian Medical Journal and Alternative Medicine

The author shares some views on health impact assessment (HIA) and environmental impact assessment (EIA)using the Four Noble Truths approach. “Suffer” of HIA includes conflicts between industries and people, people and people,people and academia, people and government agencies; HIA being more expensive and difficult; industries moving toother countries; and worst of all, the growing pollution. “Samudaya” of HIA includes social and health inequity resultingfrom developmental projects; consultants conducting EIA directly received money from industries hence having conflict ofinterest; consultants conducting EIA outsourcing health experts from universities to help in health issues; HIA was done on aproject-by-project basis, not on an …

Protest Of Doctors: A Basic Human Right Or An Ethical Dilemma, Imran Naeem Abbasi

Community Health Sciences

Background: Peaceful protests and strikes are a basic human right as stated in the United Nations' universal declaration on human rights. But for doctors, their proximity to life and death and the social contract between a doctor and a patient are stated as the reasons why doctors are valued more than the ordinary beings. In Pakistan, strikes by doctors were carried out to protest against lack of service structure, security and low pay. This paper discusses the moral and ethical concerns pertaining to the strikes by medical doctors in the context of Pakistan. The author has carefully tried to balance …

Automated Evaluation Of Approximate Matching Algorithms On Real Data, Frank Breitinger, Vassil Roussev

Electrical & Computer Engineering and Computer Science Faculty Publications

Bytewise approximate matching is a relatively new area within digital forensics, but its importance is growing quickly as practitioners are looking for fast methods to screen and analyze the increasing amounts of data in forensic investigations. The essential idea is to complement the use of cryptographic hash functions to detect data objects with bytewise identical representation with the capability to find objects with bytewise similarrepresentations.

Unlike cryptographic hash functions, which have been studied and tested for a long time, approximate matching ones are still in their early development stages and evaluation methodology is still evolving. Broadly, prior approaches have …

Seeking A Comprehensive Worldview: The Religious Seeker In The Modern World, Michael Gregory

Undergraduate Theses and Capstone Projects

Anecdotally, the casual observer of anthropological phenomenon may be led to believe that every human is basically the same. Indeed, many may assume that groups of people possess identical beliefs, religions, and expressions that hardly vary across different cultures and generations. Throughout the plethora of different cultures and the countless varieties of religious expression and experience it may seem that all of humanity is merely following the same lifestyles and worldviews as their parents and ancestors with very little change save for the gradual evolution in society. A religious studies scholar, or any scholar of the humanities, however, may notice …