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Articles 2191 - 2220 of 30965
Full-Text Articles in Entire DC Network
Bgsu Football Program November 28, 2014, Bowling Green State University. Department Of Athletics
Bgsu Football Program November 28, 2014, Bowling Green State University. Department Of Athletics
Football Programs
Football program: Bowling Green State University vs. Ball State University, Doyt L. Perry Stadium, November 28, 2014.
November 28-29, 2014, Vs. Omaha, University Of North Dakota
November 28-29, 2014, Vs. Omaha, University Of North Dakota
UND Athletics Publications: Men's Hockey
Program for the November 28-29, 2014, Subway Holiday Classic series against the Omaha Mavericks.
Inhibition Of Osteoclastogenesis And Inflammatory Bone Resorption By Targeting Bet Proteins And Epigenetic Regulation, Kyung-Hyun Park-Min, Elisha Lim, Min Joon Lee, Sung Ho Park, Eugenia Giannopoulos, Anna Yarilina, Marjolein Van Der Meulen, Baohong Zhao, Nicholas Smithers, Jason Witherington, Kevin Lee, Paul P. Tak, Rab K. Prinjha, Lionel B. Ivashkiv
Inhibition Of Osteoclastogenesis And Inflammatory Bone Resorption By Targeting Bet Proteins And Epigenetic Regulation, Kyung-Hyun Park-Min, Elisha Lim, Min Joon Lee, Sung Ho Park, Eugenia Giannopoulos, Anna Yarilina, Marjolein Van Der Meulen, Baohong Zhao, Nicholas Smithers, Jason Witherington, Kevin Lee, Paul P. Tak, Rab K. Prinjha, Lionel B. Ivashkiv
Publications and Research
Emerging evidence suggests that RANKL-induced changes in chromatin state are important for osteoclastogenesis, but these epigenetic mechanisms are not well understood and have not been therapeutically targeted. In this study we find that the small molecule I-BET151 that targets bromo and extra-terminal (BET) proteins that “read” chromatin states by binding to acetylated histones strongly suppresses osteoclastogenesis. I-BET151 suppresses pathologic bone loss in TNF-induced inflammatory osteolysis, inflammatory arthritis, and post-ovariectomy models. Transcriptome analysis identifies a MYC-NFAT axis important for osteoclastogenesis. Mechanistically, I-BET151 inhibits expression of the master osteoclast regulator NFATC1 by suppressing expression and recruitment of its newly identified upstream regulator …
Photoheterotrophic Growth Of Physcomitrella Patens, Terry M. Bricker, Adam J. Bell, Lan Tran, Laurie K. Frankel, Steven M. Theg
Photoheterotrophic Growth Of Physcomitrella Patens, Terry M. Bricker, Adam J. Bell, Lan Tran, Laurie K. Frankel, Steven M. Theg
Faculty Publications
© Springer-Verlag Berlin Heidelberg 2013. Physcomitrella patens is a model bryophyte representing an early land plant in the green plant lineage. This organism possesses many advantages as a model organism. Its genome has been sequenced, its predominant life cycle stage is the haploid gametophyte, it is readily transformable and it can integrate transformed DNA into its genome by homologous recombination. One limitation for the use of P. patens in photosynthesis research is its reported inability to grow photoheterotrophically, in the presence of sucrose and the Photosystem II inhibitor 3-(3,4-dichlorophenyl)-1,1-dimethylurea, which prevents linear photosynthetic electron transport. In this communication we describe …
People's Bank Of China And Hong Kong Monetary Authority Renewed Currency Swap Agreement (11/27/2014), Hong Kong Monetary Authority
People's Bank Of China And Hong Kong Monetary Authority Renewed Currency Swap Agreement (11/27/2014), Hong Kong Monetary Authority
Documents
Other Relevant Crises: European Sovereign Debt Crisis (2008 - 2012)
Controlling Photoreactions In Crystals And Through Confinement In Water Soluble Supramolecules, Barnali Mondal
Controlling Photoreactions In Crystals And Through Confinement In Water Soluble Supramolecules, Barnali Mondal
Open Access Dissertations
The research presented in this thesis reports various uses of supramolecules in steering photochemical and photophysical properties of small organic guest molecules. Crystals possess long range periodic arrangement of highly ordered building units and are considered as supramolecular systems. The first part of the thesis reports the use of crystals as a confined media (solid state) in directing photochemical reactions. In particular, olefins (trans 4-stilbazoles) have been directed to undergo selective [2+2] cycloaddtion in solid state. Selective photoproduct in crystals is controlled by various weak interactions in crystal lattice, which bring (pack) the reactive C=C bonds within 4.2 Å. Photoreaction …
Aspartate Β-Hydroxylase Expession Promotes A Malignant Pancreatic Cellular Phenotype, Xiaoqun Dong, Qiushi Lin, Arihiro Aihara, Gregory Gabriel
Aspartate Β-Hydroxylase Expession Promotes A Malignant Pancreatic Cellular Phenotype, Xiaoqun Dong, Qiushi Lin, Arihiro Aihara, Gregory Gabriel
Faculty Articles
Pancreatic cancer (PC) is one of the leading causes of cancer related deaths due to aggressive progression and metastatic spread. Aspartate β-hydroxylase (ASPH), a cell surface protein that catalyzes the hydroxylation of epidermal growth factor (EGF)-like repeats in Notch receptors and ligands, is highly overexpressed in PC. ASPH upregulation confers a malignant phenotype characterized by enhanced cell proliferation, migration, invasion and colony formation in vitro as well as PC tumor growth in vivo. The transforming properties of ASPH depend on enzymatic activity. ASPH links PC growth factor signaling cascades to Notch activation. A small molecule inhibitor of β-hydroxylase activity was …
Aspartate Β-Hydroxylase Expression Promotes A Malignant Pancreatic Cellular Phenotype, Xiaoqun Dong, Qiushi Lin, Arihiro Aihara, Yu Li, Chiung-Kuei Huang, Waihong Chung, Qi Tang, Xuesong Chen, Rolf Carlson, Christina Nadolny, Gregory Gabriel, Mark Olsen, Jack Wands
Aspartate Β-Hydroxylase Expression Promotes A Malignant Pancreatic Cellular Phenotype, Xiaoqun Dong, Qiushi Lin, Arihiro Aihara, Yu Li, Chiung-Kuei Huang, Waihong Chung, Qi Tang, Xuesong Chen, Rolf Carlson, Christina Nadolny, Gregory Gabriel, Mark Olsen, Jack Wands
Biomedical and Pharmaceutical Sciences Faculty Publications
Pancreatic cancer (PC) is one of the leading causes of cancer related deaths due to aggressive progression and metastatic spread. Aspartate β-hydroxylase (ASPH), a cell surface protein that catalyzes the hydroxylation of epidermal growth factor (EGF)-like repeats in Notch receptors and ligands, is highly overexpressed in PC. ASPH upregulation confers a malignant phenotype characterized by enhanced cell proliferation, migration, invasion and colony formation in vitro as well as PC tumor growth in vivo. The transforming properties of ASPH depend on enzymatic activity. ASPH links PC growth factor signaling cascades to Notch activation. A small molecule inhibitor of β-hydroxylase activity …
November 26, 2014 Cal Poly Report, Public Affairs Office
November 26, 2014 Cal Poly Report, Public Affairs Office
Cal Poly Report
No abstract provided.
Dove V. Parham: Desegregation In The Dollarway School District, Kevin Sinclair
Dove V. Parham: Desegregation In The Dollarway School District, Kevin Sinclair
Theses and Dissertations
This study examines the Dove v. Parham school desegregation case that was heard on December 16, 1959, in the United States District Court, Eastern District of Arkansas, Western Division with Judge J. Smith Henley presiding. Attorney George Howard Jr. had brought forth the lawsuit on behalf of three African American students who were denied transfer to the all-white Dollarway School District. The tactic of massive resistance had failed to stop any integration attempts in the state and was replaced by minimal compliance. The Dollarway School District chose to use pupil placement laws to avoid integration. By using transcripts from the …
A Digital History Of North Little Rock Mayor Ross Lawhon, Kimberly Anne Pipkin
A Digital History Of North Little Rock Mayor Ross Lawhon, Kimberly Anne Pipkin
Theses and Dissertations
My thesis topic is Mayor Ross Luther Lawhon and his time in the office of mayor of North Little Rock, Arkansas. Mr. Lawhon was a major player in getting the city to where it is today. Ross Luther Lawhon was born in Floresvlle, Texas on June 28, 1894. He was the son of Luther Allen and Virginia Worsham Lawhon. He served in World War I as a corporal. Mr. Lawhon came to North Little Rock, Arkansas in 1923 where he stepped into the political atmosphere of the town. He was instrumental in getting the post office of North Little Rock …
Alternative Approaches To Correction Of Malapropisms In Aiml Based Conversational Agents, Walter A. Brock
Alternative Approaches To Correction Of Malapropisms In Aiml Based Conversational Agents, Walter A. Brock
CCAC Theses and Dissertations
The use of Conversational Agents (CAs) utilizing Artificial Intelligence Markup Language (AIML) has been studied in a number of disciplines. Previous research has shown a great deal of promise. It has also documented significant limitations in the abilities of these CAs. Many of these limitations are related specifically to the method employed by AIML to resolve ambiguities in the meaning and context of words. While methods exist to detect and correct common errors in spelling and grammar of sentences and queries submitted by a user, one class of input error that is particularly difficult to detect and correct is the …
The Jfk Assassination: The Two Best Books Published Last Year, Donald E. Wilkes Jr.
The Jfk Assassination: The Two Best Books Published Last Year, Donald E. Wilkes Jr.
Popular Media
The year 2013, the 50th Anniversary of the assassination of President John F. Kennedy, produced scores of new books about the murder. Two of the best are Reclaiming Parkland and Survivor’s Guilt.
Saying Thanks Isn’T Always Simple, Melody Bowdon
Saying Thanks Isn’T Always Simple, Melody Bowdon
UCF Forum
Tomorrow is Thanksgiving, and people all over the country will gather around tables with loved ones to express thanks for time together, getting through another year, and green bean casserole.
Giving Thanks, Michelle Morrissey
Volume 52, Number 15: November 26, 2014, University Of North Dakota
Volume 52, Number 15: November 26, 2014, University Of North Dakota
University Letter Archive
No abstract provided.
Paintings: Perceptions Of Ordinary Moments, Laura Brainard Raborn
Paintings: Perceptions Of Ordinary Moments, Laura Brainard Raborn
Theses and Dissertations
By depicting the human figure in ordinary moments, I highlight mundane, yet important, actions in daily life. In order to captivate the viewer, I use specific formal elements: abstraction that contrasts areas of representation, evidence of drawn line, a variety of high contrasts, and repetition of forms. I also use a layering technique to obscure or reveal information selectively. These formal elements are employed to compel the viewer to thoughtfully question and consider the presented figure. This body of work was inspired by my ideas about social norms and modern culture. Contemporary painters such as Eric Fischl and Jenny Saville …
A Vision For Change In Bioscience Education: Building On Knowledge From The Past, Nancy J. Pelaez, Trevor R. Anderson, Samuel N. Postlethwait
A Vision For Change In Bioscience Education: Building On Knowledge From The Past, Nancy J. Pelaez, Trevor R. Anderson, Samuel N. Postlethwait
PIBERG Publications
High quality undergraduate education is central to the success of all life scientists. Several major bioscience educational issues are the targets of much debate, research, funding, publications, and reports (e.g. Vision and Change). Surprisingly, these issues are considered by modern bioscience instructors as unresolved despite historical reports that claim the contrary. Here we illustrate with evidence how, more than 50 years ago, Sam Postlethwait successfully instituted strategies to address several issues in plant biology education with his audio-‐tutorials. These strategies succeeded in individualizing instruction of students with diverse educational backgrounds in large classes, incorporating authentic and active learning, integrating lab …
Leo P. Mclaughlin: Undisputed Boss Of Hot Springs, John H. Jones
Leo P. Mclaughlin: Undisputed Boss Of Hot Springs, John H. Jones
Theses and Dissertations
This project involves exploring the life of Leo Patrick McLaughlin, especially his time as mayor of Hot Springs, by web exhibit, http://leopmclaughlin.omeka.net/exhibits/show/leo-patrick-mclaughlin--the-un. The goal is to inform readers of this colorful character in Arkansas history. This has been achieved by examining the gambling syndicate and political machine that McLaughlin created, as well as his connections with underworld figures such as Al Capone, Bugs Moran, and other criminals on the Most Wanted list. Upon examination of these connections, it will become clear to readers that Mayor McLaughlin began to think himself untouchable, demonstrated by his attempts to take on Governor Carl …
Ferguson — What Now?, Timothy Zick
Keynote Address: Proposals For The Future, Louis B. Sohn
Keynote Address: Proposals For The Future, Louis B. Sohn
Georgia Journal of International & Comparative Law
No abstract provided.
The Politics Of Ratification: The Potential For United States Adoption And Enforcement Of The Convention Against Torture, The Covenants On Civil And Political Rights And Economic, Social And Cultural Rights, Winston P. Nagan
Georgia Journal of International & Comparative Law
No abstract provided.
Range Of Horizontal Transport And Residence Time Of Nitrate In A Mature Karst Vadose Zone, Jiri Kamas, Jiri Bruthans, Helena Vysoka, Miroslav Kovařík
Range Of Horizontal Transport And Residence Time Of Nitrate In A Mature Karst Vadose Zone, Jiri Kamas, Jiri Bruthans, Helena Vysoka, Miroslav Kovařík
International Journal of Speleology
Nitrate concentrations in drips in Amaterska, Spolecnak, and Holstejnska caves situated below a 25 to 120 m thick vadose zone in the Moravian Karst, Central Europe were studied during several periods from 1992. Each cave runs below a land-use boundary between fertilized lands and forest, which enabled study of the range of horizontal components of nitrate transport in the vadose zone. Parts of the fertilized land were turned into grassland in 1998 and 2003, and the cave drips were sampled both prior and after the changes in land use. The mean residence time of nitrate is - 30 m thick …
Unmanned Aerial Vehicles: Legitimate Weapon Systems Or Unlawful Angels Of Death?, Michael J. Deegan
Unmanned Aerial Vehicles: Legitimate Weapon Systems Or Unlawful Angels Of Death?, Michael J. Deegan
Pace International Law Review
Since the invasion of Afghanistan, the United States has utilized Unmanned Aerial Vehicles (UAVs) to locate, surveil and kill members of the Taliban, Al-Qaeda and its associated forces. Such killings have decimated the leadership of these groups and disrupted their operations. However, there are collateral effects from UAV killings including civilian deaths. These deaths increase resentment and hatred toward the US, which is channeled by terrorist groups to recruit new members and for local support. Moreover, targeted killings outside a combat zone have political and diplomatic consequences. This paper argues that the current uses of UAV are legal under international …
When Words Defile Things: Homoerotic Desire And Extreme Depictions Of Masculinity In Shakespeare’S Coriolanus And, Aaron Hubbard
When Words Defile Things: Homoerotic Desire And Extreme Depictions Of Masculinity In Shakespeare’S Coriolanus And, Aaron Hubbard
Selected Papers of the Ohio Valley Shakespeare Conference
No abstract provided.
Jean-François Ducis: Re-Creating Shakespeare For An Eighteenth-Century Audience, Amy Drake
Jean-François Ducis: Re-Creating Shakespeare For An Eighteenth-Century Audience, Amy Drake
Selected Papers of the Ohio Valley Shakespeare Conference
No abstract provided.
A Hot Mess: Knowing Juliet Through Accidental Encounters In Popular Culture, Kirk Hendershott-Kraetzer
A Hot Mess: Knowing Juliet Through Accidental Encounters In Popular Culture, Kirk Hendershott-Kraetzer
Selected Papers of the Ohio Valley Shakespeare Conference
No abstract provided.
Front Matter, Hillary Nunn
Front Matter, Hillary Nunn
Selected Papers of the Ohio Valley Shakespeare Conference
No abstract provided.
Untitled Film Still, Risd Museum, A. Will Brown
Untitled Film Still, Risd Museum, A. Will Brown
Channel
When making his prints, animations, and light boxes, Ezawa looks for source images on the Internet, manipulates them, and distills them to their essentials. Untitled Film Still belongs to a series of works for which Ezawa appropriated several famous photographs in order to deal with the questions of why some images become icons and how one looks at and interprets imagery. It is a playful appropriation of Cindy Sherman’s photograph with the same title from 1978. Sherman’s seminal Untitled Film Still series was in fact single photographs in which a female character (always played by Sherman herself) is trapped in …