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Analysis Of Drug Interactions With Lipoproteins By High Performance Affinity Chromatography, Matthew R. Sobansky

Department of Chemistry: Dissertations, Theses, and Student Research

High density lipoprotein (HDL), low density lipoprotein (LDL), and very low density lipoprotein (VLDL) are lipoproteins previously shown to bind many basic and neutral hydrophobic drugs in serum. These interactions impact the distribution, delivery, metabolism, and excretion of drugs and are important in determining drug activity, pharmacokinetics, and toxicity in the human body. Information about drug-lipoprotein interactions and the strength of these interactions can be useful in determining the distribution of drugs following administration.

The research presented in this dissertation uses high performance affinity chromatography (HPAC) and packed columns to study binding of the drug propranolol to immobilized lipoproteins such …

Molecular Dynamics Study Of The Opening Mechanism For Dna Polymerase I, Carol A. Parish, Bill R. Miller Iii, Eugene Y. Wu

Chemistry Faculty Publications

During DNA replication, DNA polymerases follow an induced fit mechanism in order to rapidly distinguish between correct and incorrect dNTP substrates. The dynamics of this process are crucial to the overall effectiveness of catalysis. Although Xray crystal structures of DNA polymerase I with substrate dNTPs have revealed key structural states along the catalytic pathway, solution fluorescence studies indicate that those key states are populated in the absence of substrate. Herein, we report the first atomistic simulations showing the conformational changes between the closed, open, and ajar conformations of DNA polymerase I in the binary (enzyme:DNA) state to better understand its …

College Of Engineering Senior Design Competition Fall 2014, University Of Nevada, Las Vegas

Fred and Harriet Cox Senior Design Competition Projects

Part of every UNLV engineering student’s academic experience, the senior design project stimulates engineering innovation and entrepreneurship. Each student in their senior year chooses, plans, designs, and prototypes a product in this required element of the curriculum. A capstone to the student’s educational career, the senior design project encourages the student to use everything learned in the engineering program to create a practical, real world solution to an engineering challenge. The senior design competition helps focus the senior students in increasing the quality and potential for commercial application for their design projects. Judges from local industry evaluate the projects on …

Assembling 3d Objects With Artificial Spatial Intelligence, Eugene Koon

Theses

The focus of this thesis is to provide an artificial intelligence (AI) system that can develop spatial intelligence. A MATLAB application of a genetic algorithm AI system has been implemented. The AI system will incorporate three dimensional (3D) objects that can learn to maneuver in 3D space so that they may be assembled with each other. As an example, two rectangles with holes and a nut will maneuver itself onto a screw. The performance of the AI system will then be recorded as video results.

The George-Anne, Georgia Southern University

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Farmers Markets In Urban Us Counties: The Relationship Between Income, Obesity, And Access, Mia El-Hamaki

Earth and Environmental Sciences Presentations

In the last decade there has been a convergence of factors that have contributed to an increase in food deserts, obesity, and income inequality in the US. Two-thirds of US adults are overweight or obese. This prevalence disproportionately affects low income areas with high minority populations (Ruelas et al., 2012). Simultaneously, research shows that grocery stores are tending to move away from low income, inner city communities and towards affluent urban and suburban areas. In order to combat the growing food deserts and obesity rates as a result of this shift, farmers markets have been proposed and utilized as a …

Wing And Fin Outfitters: Using Gis To Determine The Ideal Location For A Tackle Shop In Charleston, Sc, Matt Giordano

Earth and Environmental Sciences Presentations

A few years down the road I hope to open a tackle shop in Charleston, South Carolina with my current college roommate. I have been fishing my entire life and since coming down to school I have spent many breaks down in Charleston. My interest in the area really blossomed during the summer of 2013 which I spent in Charleston fishing and working around the water. During my time in Charleston I have realized that many local shops are in good locations but they do not provide excellent service. Shops seem to get by on reputation rather than actual service. …

A Comparison Of Trout Streams: Examining The Reasons For Angler Visitation To Certain Counties Around North Carolina, Rob George

Earth and Environmental Sciences Presentations

Recreational fishing is a popular and profitable sport for states across the country (Ditton et al., 2002). Mountain trout angling provides as much as 174 million dollars annually to the state of North Carolina (NCWRC, 2009). This number shows that recreational trout fishing is an important economic factor for North Carolina. The goal of this project is to determine what variables correlate to the popularity of a county among trout anglers. Through personal experience, academic articles, and interviews with fly fishermen a list of variables was created in order to compare two streams in different counties. These variables include household …

Urban Garden Survival, Phoebe Ferguson, Rachel Martin

Biology Presentations

Urban gardens are community led plots designated for agricultural purposes in residential and urban areas. Greenville County has seen a recent growth in urban gardens with the assistance of non-profit groups like Gardening for Good. The current total in Greenville County stands at 79 with new gardens added every year. While the growth is encouraging, some gardens have failed. This study uses GIS to explore the social and ecological factors that correlate with urban garden survival in an effort to provide garden managers with information that will help them develop gardens that thrive and persist.

Analyzing Drone Footage To Assess Necessary Streetlight Placement: Where In New Washington Heights And Poe Mill Are Streetlights Most Necessary?, Savannah Jennings, Billy Tutt

Earth and Environmental Sciences Presentations

New Washington Heights and Poe Mill are low income neighborhoods with high crime rates and the people living there feel that more street lights would make the areas more safe at night. In our project, we aimed to answer the question: where are streetlights most appropriate in these neighborhoods? And can footage taken from the recent drone flyover help to improve our ability to accurately model streetlights in these neighborhoods? We will present our findings to the residents of Poe Mill and New Washington Heights in order to aid their efforts in making their streets safer. This question is relevant …

Spartanburg Humane Society Data Analysis: Hotspots And Resource Management, Leigh Robertson

Earth and Environmental Sciences Presentations

A data set from the Spartanburg Humane Society was provided with the hope that the use of GIS could show patterns and hotspots of dog and cat pickup locations. With a better understanding of where the majority of the animals come from, the Humane Society can better distribute their man power and resources to help as many homeless animals as possible. According to Beck (1973) the main reasons for stray and abandoned animals is negligence causing pet releases or escapes, and also breeding. Therefore, finding and targeting areas where there are many strays (potentially as a result of a release, …

Lion Tales: The Impact Of Educational Policy Discourse On The Perpetuation Of The Perception Of African American Academic Underachievement, Marshetta Shavon Brazley

Electronic Theses and Dissertations Archive

Academic achievement for African American students has remained consistently low over time. Some researchers cite the disintegration of the black family as the cause. Others have argued that IQ is largely influenced by genetics, and that African Americans are genetically predisposed to be less intelligent than other races. One researcher traces the socio-historical connection between the institution of slavery and the current inequality inherent in the American education system. He also contends that the differences between African American culture and mainstream culture are so great that they adversely impact African American academic achievement. The purpose of the critical comparative discourse …

Mitigation Of Decubitus Ulcers By Moisture Reduction In Bedridden Catheterized Patients, Kory A. Robinson

Electronic Theses and Dissertations Archive

In today's society, decubitus ulcers are a serious and very common medical condition. Yet, they constitute a major complication threatening indiviuals in hospitals, nursing homes and family homecare environments. Decubitus ulcers usually represent a major burden of care and reduces the quality of life considerably for patients, as well as their care givers. Ironically, most patients develop decubitus ulcers after an extended stay in a hopital or acute care facilities. Decubitus ulcers present challenges to the healthcare industry because they are associated with increased risks of baterial infections, longer hospital stays and higher hospitialization costs. The purpose of this thesis …

A Scientometric Assessment Of Indian Himalayan R&D Publications During 2004-13, Brij Mohan Gupta Dr, Ritu Gupta

Library Philosophy and Practice (e-journal)

The paper analyses 9909 global and 4862 Indian Himalayan R&D publications, as covered in Scopus database during 2004-13. It compares the contribution, citation impact and international collaborative publications share of top 10 most productive countries, and the place of Indiaamong them. It mainly examines Indian output, with a focus its annual average growth rate (13.21%), citation impact per paper (1.86%), distribution of citations (with 62.40% publications received one or more citations), share of international collaborative papers (16.29%) and contribution of leading collaborative countries, distribution of output by broad subject areas, publication productivity and citation impact of thirty leading institutions and …

Achieving Success With Pbis: The Teacher’S Role, Adrienne Boisson, Andre Byrd, Chris Williams

Georgia Association for Positive Behavior Support Conference

The goal of this presentation is to help high school teachers feel less overwhelmed with the idea of implementing PBIS in their daily routine:

• By clearly delineating the PBIS initiative, a definition of what PBIS is and what PBIS isn’t, how PBIS can impact your school culture, and the importance of data sharing
• By offering a step-by-step guide of what it looks like to implement PBIS in your classroom on a daily/weekly/monthly basis
• By providing PBIS resources, strategies, and examples of PBIS best practices utilized at NHS

Rambassadors: Making Student Leadership The Cornerstone Of Pbis Success, Adrienne Boisson, Andre Byrd, Chris Williams

Georgia Association for Positive Behavior Support Conference

The goal of this presentation is to share the impact of a successful PBIS student advisory organization. Presenters will give an in-depth explanation of the development of their program to include:

1. We are RAMS: the history of PBIS at Newton High School and how it influences school culture.
2. RAMbassadorS: Modeling the Ideal RAMS; using students to exemplify school expectations of success focusing on the following characteristics: mindset, service, and appearance
3. Laying the groundwork: Preparing student leaders for service from application process to active duty

The Influence Of Electronic Resources Use On Students’ Reading Culture In Nigerian Universities: A Case Study Of Adeleke University Ede, Osun State, Stephen Adekunle Ajayi, Oludare A. Shorunke, Modupe A. Aboyade Mrs

Library Philosophy and Practice (e-journal)

The declining interest in reading among students in higher institution is a challenge to all, as it affects the educational standard and the quality of graduate sent into the society. Survey method was used to carry out this research and the target population was students of Adeleke University Ede which totalled 705. A random sampling method was adopted for the research work. A total number of 220 were sampled from the total population. A well structured questionnaire was the instrument used to gather data for the study. A total of 220 questionnaires was administered on the respondents, 212 copies were …

E-Book Reading And Its Impact On Academic Status Of Students At Payame Noor University, Iran, Ali Biranvand, Ali Akbar Khasseh

Library Philosophy and Practice (e-journal)

The purpose of this study is to explore the effect of taking advantage of electronic books on the academic progress of students at Payame Noor University, Iran. This research is of descriptive and survey methodology. The statistical population includes the students of public administration in Shiraz Payame Noor University, who are studying in the academic year 2013-2014. 142 students have been chosen by simple random sampling.

Results indicated that use of electronic resources causes a meaningful difference to be created in several contexts such as academic progress, variety of learning resources, flexibility while learning, and learning effectiveness between the students …

December 3, 2014 Cal Poly Report, Public Affairs Office

Cal Poly Report

No abstract provided.

Principles For Optimizing The Scale Of Direct Potable Water Reuse: Economic Network Modeling Studies, Tianjiao Guo

Open Access Dissertations

The US National Research Council recently recommended direct potable water reuse (DPR), or potable water reuse without environmental buffer, for consideration to address rising US water demand. In addition, conveyance of wastewater and water to and from centralized treatment plants currently consumes on average four times the energy of treatment in the US. Moreover, scaling of DPR systems involves tradeoffs beyond those of treatment facility economy-of-scale versus cost and energy of conveyance. In particular, additional factors favoring distributed DPR include minimization of energy for upgradient distribution of treated water, and retention of wastewater thermal energy. Therefore, a network modeling study …

Contesting Risk, Precaution And Legitimacy: A Case Study Of Lafarge, Savitri Vasanta Gordian

LLM Theses

This thesis examines debates about the precautionary principle in a tribunal and judicial review proceeding where environmental groups and individuals challenged a proposal to burn tires and other non-traditional fuel sources at a cement plant in Ontario, Canada. Chapter 1 explores scholarship on the precautionary principle and outlines the unique analytical contributions offered by administrative constitutionalism theory. Chapter 2 sets out the case study methodology employed by the author. Chapter 3 explains the legislative context. In chapters 4 through 9, each participant’s arguments are analyzed in relation to the two paradigms of administrative constitutionalism: Rational-Instrumentalist and Deliberative-Constitutive. This thesis establishes …

An Investigation Of The Factors Contributing To Measurement Uncertaintly Using A Coordinate Measurement Machine, Jayson S. Minix

Morehead State Theses and Dissertations

A thesis presented to the faculty of the College of Science and Technology at Morehead State University in partial fulfillment of the requirements for the Degree of Master of Science in Engineering & Technology Management by Jayson S. Minix on December 3, 2014.

Governors State University Announces Commitment To Expand College Access At White House Event, Office Of Marketing And Communications

Press Releases

Today, Governors State University President Elaine P. Maimon joins President Obama, the First Lady, and Vice President Biden along with hundreds of college presidents and other higher education leaders to announce new actions to help more students prepare for and graduate from college.

The White House College Opportunity Day of Action helps to support the President’s commitment to partner with colleges and universities, business leaders, and nonprofits to support students across the country to help our nation reach its goal of leading the world in college attainment.

Governors State University, along with five partner community colleges, commits to collectively producing …

Hf Accelerated Electron Fluxes, Spectra, And Ionization, Herbert C. Carlson, Joseph B. Jensen

All Physics Faculty Publications

Wave particle interactions, an essential aspect of laboratory, terrestrial,and astrophysical plasmas, have been studied for decades by transmitting high power HF radio waves into Earth’s weakly ionized space plasma, to use it as a laboratory without walls. Application to HF electron acceleration remains an active area of research (Gurevich, 2007) today. HF electron acceleration studies began when plasma line observations proved (Carlson et al, 1982) that high power HF radio wave-excited processes accelerated electrons not to ~ eV, but instead to - 100 times thermal energy (10s of eV), as a consequence of inelastic collision effects on electron transport. Gurevich …

We Are...Marshall, December 3, 2014, Office Of Marshall University Communications

We Are ... Marshall: the Newsletter for Marshall University 1999-2023

No abstract provided.

Outstanding Educational Performance Awards: Highlighting High-Achieving Arkansas Schools, 2014, Charlene A. Reid, Gary W. Ritter

Arkansas Education Reports

The GPA measure, we believe, is a better representation of student achievement on statewide standardized exams. In this report, we are presenting a list of the top 25 schools in each area. In some cases, these "top 25 lists" will contain more than 25 schools as some schools' GPA scores will be identical. This is not a new phenomenon, as we also exceeded 25 schools in previous reports when using the percent proficient and advanced metric as an indicator for student achievement; however, there are fewer ties using the more precise GPA measure.

After we present our overall snapshot of …

Customising Doctor-Nurse Communications, Brian Cusack, Dave Parry

Australian eHealth Informatics and Security Conference

Doctor-Nurse communications are critical for patient safety and workflow effectiveness. Our research question was: What further improvements can be made to current communication systems? A variety of mobile and land based communication systems have been used and experimented with. In the study, the pager was found to be most common and more recent attempts to provide broadband capability with systems such as the iBeep. We built an alternative information system using Android phones and a software application that was customised by feedback from the medical professionals. The trial in five wards with 22 doctors and 170 nurses over one month …

Security Of Electronic Health Records In A Resource Limited Setting: The Case Of Smart-Care Electronic Health Record In Zambia, Keith Mweebo

Australian eHealth Informatics and Security Conference

This paper presents a case study of security issues related to the operationalization of smart-care, an electronic medical record (EMR) used to manage Human Immunodeficiency Virus (HIV) health information in Zambia. The aim of the smart-care program is to link up services and improve access to health information, by providing a reliable way to collect, store, retrieve and analyse health data in a secure way. As health professionals gain improved access to patient health information electronically, there is need to ensure this information is secured, and that patient privacy and confidentiality is maintained. During the initial stages of the program …

The Potentials And Challenges Of Big Data In Public Health, Rena N. Vithiatharan

Australian eHealth Informatics and Security Conference

The potential to use big data sources for public health increases with the broadening availability of data and improved methods of analysis. Whilst there are some well-known examples of the opportunistic use of big data, such as GoogleFlu, public health has not yet realised the full potential of such data sources. A literature review was undertaken to identify the potential of such data collections to impact public health, and to identify what challenges are currently limiting this potential. The potential include improved real-time analysis, research and development and genome studies. However, challenges listed are poor universal standardisation and classification, privacy …

Byod In Ehealth: Herding Cats And Stable Doors, Or A Catastrophe Waiting To Happen?, Krishnun Sansurooh, Patricia A H Williams

Australian eHealth Informatics and Security Conference

The use of personal devices in the work environment has crossed the boundaries of work and socially related tasks. With cyber criminals seriously targeting healthcare for medical identity theft, the lack of control of new technologies within healthcare networks becomes an increasing vulnerability. The prolific adoption of personal mobile devices in the healthcare environment requires a proactive approach to the management of Bring Your Own Device (BYOD). This paper analysed the current state of the problem and the challenges that this creates in an environment that has stringent privacy and security requirements. The discourse demonstrates that the issue is not …