Digital Commons Network^™

Ageism, Honesty, And Trust, Eric Schniter, Timothy W. Shields

ESI Publications

Age-based discrimination is considered undesirable, yet we know little about age stereotypes and their effects on honesty and trust. To investigate this aspect of ageism, we presented older adults (over age 50) and younger adults (under age 25) with incentivized belief elicitation tasks about anticipated interaction behaviors and then a series of same, different, and unknown-aged group interactions in a strategic-communication game. All adults shared consensual stereotypes about uncooperative younger adults and cooperative older adults that demonstrated “wisdom of crowds”. While the out-group was consistently stereotyped as relatively different and more dishonest and suspicious than observed to be, the in-group …

Facing The Controversy: A Grounded Theory Study Of How Teachers Plan To Address Climate Change In Their Classrooms, Thomas J. Frankie

Education Doctoral

Climate change is a subject steeped in controversy. Addressing it in the classroom causes much anxiety for teachers as they struggle with how to teach it. The purpose of this grounded theory study was to uncover the information teachers deem most important to communicate to their students about climate change and the pedagogical strategies they plan to employ in doing so. This study analyzed the responses of 123 teachers who successfully completed an online climate change course. Each teacher provided qualitative data in the form of a response to a course assignment. Analysis of those responses revealed that teachers saw …

Facing The Wreck: Death, Optimism, And The Fragmented Form, Rachael Marie Schaffner

Graduate Theses and Dissertations

Walter Benjamin described history as a winged angel who faces backwards, staring perpetually into the past as the violent winds of destiny carry him into the future (Illuminations). Despite a western, post-enlightenment myth of eternal progress, the wreckage of human contributions to history is clearly evident in our 21st-century understanding of anthropogenic impact on global ecology. In the context of these ecological crises (and the resulting political and economic questions), postmodern novels reveal a powerful ability to imagine different ways of living and interacting with the world. This thesis traces the relationship between fragmentation, death, and liminal experiences …

Tackling The Existing Burden Of Infectious Diseases In The Developing World: Existing Gaps And The Way Forward, Zulfiqar Ahmed Bhutta, Rehana A. Salam, Jai K. Das, Zohra S. Lassi

Department of Paediatrics and Child Health

This series evaluates the effectiveness of community-based interventions (CBIs) to prevent and control infectious diseases of poverty (IDoP). Evidence from our reviews suggests that CBIs and school-based delivery platforms are effective in averting risk behaviors and reducing the disease burden. Co-implementation of interventions through existing community-based programs including immunization campaigns, antenatal care and maternal and child health programs have the potential to scale-up interventions for IDoP. Future research should focus on the process of developing and implementing efficient community-based programs through a comprehensive approach, and to gauge the effectiveness of various existing delivery models in order to improve morbidity and …

Transition From Hospital To Home Following Pediatric Solid Organ Transplant: Qualitative Findings Of Parent Experience, Stacee M. Lerret, Marianne E. Weiss, Gail Stendahl, Shelley Chapman, Katie Neighbors, Joan Lokar, Ashley Voit, Jerome Menendez, Estella M. Alonso

College of Nursing Faculty Research and Publications

Transplant providers are challenged to determine appropriate interventions for patients and families due to limited published research regarding the context of the post-discharge experience from the perspective of parents of transplanted children. The purpose of this study is to describe the parent perspective of the transition from hospital to home following their child's solid organ transplant. Within a mixed-methods design, 37 parents of pediatric heart, kidney, and liver transplant recipients from three pediatric hospitals responded to qualitative interview questions on the day of hospital discharge and three wk following hospital discharge. Insight to the discharge preparation process revealed necessary education …

Dispositional Optimism: Modeling Cardiovascular Disease Mortality With Traditional Risk Factors And A Psychosocial Personality Trait, Kiana Ramisi Luckett Robinson

Dissertations

Despite increased awareness of clinical risk factors for cardiovascular disease (CVD), heart disease remains a physical and economic burden to African Americans. The aim of this study was to investigate the relationship between dispositional optimism, a psychosocial personality trait, and CVD mortality, based on immediate cause of death. A cross-sectional design was used to examine the predictive value of dispositional optimism in CVD mortality concomitant with traditional CVD risk factors. The traditional CVD risk factors of interest consisted of body mass index, waist circumference, systolic and diastolic blood pressures, total cholesterol, and C-reactive protein. Also, aggregated mortality data for optimists …

Anxiety, Depression And Smoking Status Among Adults Of Mexican Heritage On The Texas-Mexico Border, Anna V. Wilkinson, Kristina Vatcheva, Adriana Pérez, Belinda M. Reininger, Joseph B. Mccormick, Susan P. Fisher-Hoch

School of Mathematical & Statistical Sciences Faculty Publications

The goal of the current analysis is to examine relationships between smoking status and anxiety and depression among adults of Mexican heritage to inform the development of culturally relevant smoking cessations efforts. Mexican heritage residents (N=1,791) of the city of Brownsville, TX, aged 18 years or older, enrolled in the Cameron County Hispanic Cohort, were selected through two stage cluster sampling of randomly selected census tracts from the first and third quartile of SES using Census 2000. Among current smokers, anxiety and depression scores were highest among women who had not completed high school (p<0.05). Former smoking women, but not men, with at least a high school education and former smoking women born in the United States reported higher levels of anxiety and depression than never smoking women. Negative affective states may represent a greater barrier to smoking cessation among women than men.

Empiric Deworming And Cd4 Count Recovery In Hiv-Infected Ugandans Initiating Antiretroviral Therapy, Alexander J. Lankowski, Alexander C. Tsai, Michael Kanyesigye, Mwebesa B. Bwana, Jessica E. Haberer, Megan Wenger, Jeffrey N. Martin, David Bangsberg, Peter W. Hunt, Mark J. Siedner

OHSU-PSU School of Public Health Faculty Publications and Presentations

Background: There is conflicting evidence on the immunologic benefit of treating helminth co-infections (‘‘deworming’’) in HIV-infected individuals. Several studies have documented reduced viral load and increased CD4 count in antiretroviral therapy (ART) naive individuals after deworming. However, there are a lack of data on the effect of deworming therapy on CD4 count recovery among HIV-infected persons taking ART.

Methodology/Principal Findings: To estimate the association between empiric deworming therapy and CD4 count after ART initiation, we performed a retrospective observational study among HIV-infected adults on ART at a publicly operated HIV clinic in southwestern Uganda. Subjects were assigned as having received …

South Africans With Recent Pregnancy Rarely Know Partner’S Hiv Serostatus: Implications For Serodiscordant Couples Interventions, Lynn T. Matthews, Lizzie Moore, Tamaryn L. Crankshaw, Cecilia Milford, Fortunate N. Mosery, Ross Greener, Christina Psaros, Steven A, Safren, David Bangsberg, Jennifer A. Smit

OHSU-PSU School of Public Health Faculty Publications and Presentations

Background: Implementation of safer conception strategies requires knowledge of partner HIV-serostatus. We recruited women and men in a high HIV-prevalence setting for a study to assess periconception risk behavior among individuals reporting HIV-serodiscordant partnerships. We report screening data from that study with the objective of estimating the proportion of individuals who are aware that they are in an HIV-serodiscordant relationship at the time of conception.

Methods: We screened women and men attending antenatal and antiretroviral clinics in Durban, South Africa for enrollment in a study of periconception risk behavior among individuals with serodiscordant partners. Screening questionnaires assessed for study eligibility …

Vaccines To Combat River Blindness: Expression, Selection And Formulation Of Vaccines Against Infection With Onchocerca Volvulus In A Mouse Model., Jessica A. Hess, Bin Zhan, Sandra Bonne-Annee, Jessica M. Deckman, Maria Elena Bottazzi, Peter J. Hotez, Thomas R R. Klei, Sara Lustigman, David Abraham

Department of Microbiology and Immunology Faculty Papers

Human onchocerciasis is a neglected tropical disease caused by Onchocerca volvulus and an important cause of blindness and chronic disability in the developing world. Although mass drug administration of ivermectin has had a profound effect on control of the disease, additional tools are critically needed including the need for a vaccine against onchocerciasis. The objectives of the present study were to: (i) select antigens with known vaccine pedigrees as components of a vaccine; (ii) produce the selected vaccine antigens under controlled conditions, using two expression systems and in one laboratory and (iii) evaluate their vaccine efficacy using a single immunisation …

Reincarnation, Goodbye: 1992, Constance Urdang

Ontario Review

Constance Urdang is the author of a number of books, including Alternative Lives, poems (Pittsburgh), and The Woman Who Reads Novels and Peacetime, novellas (Coffee House Press). She lives in St. Louis.

Examining Social Support In A Rural Homeless Population, Afton Jackson, Lisa Shannon

Journal of Rural Social Sciences

The purpose of this study was to examine factors associated with social support in a rural, homeless population. Ninety-six (N= 96) individuals voluntarily agreed to participate in an evaluation examining effectiveness of enhanced substance use and mental health services provided to homeless individuals. The primary variables of interest were: demographics, substance use, mental and physical health, and social support. We used bivariate analyses to examine the sample using two different indicators of past-thirty-day social support: (1) family/friend social support [no support/support] and (2) self-help group social support [no support groups/support groups]. We used two multivariate logistic regressions to examine the …

Prognostic Value Of A Quantitative Analysis Of Lipoarabinomannan In Urine From Patients With Hiv-Associated Tuberculosis, Andrew D. Kerkhoff, Robin Wood, Monica Vogt, Stephen D. Lawn

Medicine Faculty Publications

Background

Detection of the mycobacterial cell wall antigen lipoarabinomannan (LAM) in urine can be used to diagnose HIV-associated tuberculosis (TB) using a qualitative (positive/negative) read-out. However, it is not known whether the quantity of LAM present in urine provides additional prognostic information.

Methods/Findings

Consecutively recruited adult outpatients initiating antiretroviral therapy (ART) in South Africa were investigated for TB regardless of clinical symptoms using sputum smear microscopy and liquid culture (reference standard). Urine samples were tested using the Clearview TB-ELISA for LAM and the Xpert MTB/RIF assay. The ELISA optical densities (OD) were used as a quantitative assessment of urine LAM. …

Demonstrating The Use Of High-Volume Electronic Medical Claims Data To Monitor Local And Regional Influenza Activity In The Us, Cecile G. Viboud, Vivek Charu, Donald R. Olson, Sebastien Ballesteros, Julia R. Gog, Farid Khan, Bryan T. Grenfell, Lone Simonsen

Global Health Faculty Publications

Introduction

Fine-grained influenza surveillance data are lacking in the US, hampering our ability to monitor disease spread at a local scale. Here we evaluate the performances of high-volume electronic medical claims data to assess local and regional influenza activity.

Material and Methods

We used electronic medical claims data compiled by IMS Health in 480 US locations to create weekly regional influenza-like-illness (ILI) time series during 2003–2010. IMS Health captured 62% of US outpatient visits in 2009. We studied the performances of IMS-ILI indicators against reference influenza surveillance datasets, including CDC-ILI outpatient and laboratory-confirmed influenza data. We estimated correlation in weekly …

Production Of Recombinant Human Coagulation Factor Ix By Transgenic Pig, Weijie Xu

Department of Chemical and Biomolecular Engineering: Dissertations, Theses, and Student Research

Hemophilia B is the congenital bleeding disorder caused by deficiency in functional coagulation factor IX (FIX) and about 28,000 patients worldwide in 2012. And current treatment is restricted to protein-replacement therapy, which required FIX concentrates for patients’ life-time. Approximately 1 billion units FIX were consumed in 2012. However, still about 70-80% patients, mostly in developing countries, received inadequate or no treatment because of the unavailable and/or unaffordable FIX concentrates. Considering safety reasons, e.g. transmission of blood-borne diseases, the recombinant human FIX (rFIX) is recommended other than the plasma-derived FIX. However, only one rFIX is currently available on the market. The …

Adherence Inhibition Of Human Pathogens Campylobacter Jejuni And Campylobacter Coli By Non-Digestible Oligosaccharides, Alejandra Ramirez-Hernandez

Department of Food Science and Technology: Dissertations, Theses, and Student Research

Adherence is the first and one of the most important steps of bacterial pathogenesis. Natural derived components that inhibit the adherence of pathogens to the surface of epithelial cells have received considered interest. The goal of this research was to assess the anti-adherence activity of mannan oligosaccharides (MOS), pectic oligosaccharides (POS) and cranberry high molecular weight component (HMW) against Campylobacter jejuni and Campylobacter coli. First the anti-adherence activity of MOS and their purified fraction (pMOS) was tested against three strains of C. jejuni and two strains of C. coli. Results shown significant reductions in adherence (up to 70%) …

Cervical Spine Osteomyelitis After Esophageal Dilation In Patients With A History Of Laryngectomy Or Pharyngectomy And Pharyngeal Irradiation, Richard A. Goldman, Md, Jill N. D'Souza, Md, Adam J. Luginbuhl, Md, Joshua E. Heller, Md, Joseph M. Curry, Md, David M. Cognetti, Md

Department of Otolaryngology - Head and Neck Surgery Presentations and Grand Rounds

Dysphagia is a common sequela of the treatment of head and neck cancer and is frequently managed with esophageal dilation in patients with dysphagia secondary to hypopharyngeal stenosis. Reported complications of esophageal dilation include bleeding, esophageal perforation, and mediastinitis. We examine four cases of cervical spine osteomyelitis presenting as a delayed complication of esophageal dilation for hypopharyngeal stenosis in patients with a history of laryngectomy or pharyngectomy and radiation with or without chemotherapy. The history of head and neck surgery and radiation in these patients further complicates the management of the cervical spine osteomyelitis.

Reminder For Adults: Immunizations Are Still Needed And Can Be Lifesaving, Jim Bakken

Browse All News

No abstract provided.

2014-July-25-Biomedical Research Center, University Marketing And Communications, East Tennessee State University

ETSU News

No abstract provided.

Assessing The Prevalence Of Human Pathogens In Lehigh Valley’S Deer Ticks, Amulya Makkapati

Research Scholars Poster Presentation

Abstract

Ixodes scapularis are vectors for human pathogens including Borrelia burgdorferi, Anaplasma phagocytophilum, Babesia microti, and the emerging infectious agent, Borrelia miyamotoi. The goal of this study was to determine the prevalence of these tick-borne pathogens in deer ticks in the Lehigh Valley of eastern Pennsylvania, where tick populations are abundant. By doing so, the epidemiological risks to humans could be assessed and this information used to guide health care providers in the region. To be sensitive and specific in testing for these pathogens, real-time PCR was performed on DNA extracted from ticks. Nested conventional PCR …

Evaluating Engagement In The Populytics Chronic Condition Management Health Coaching Program, Kristen Dziedzic, Deborah Cook-Altonji Rn, Msn

Research Scholars Poster Presentation

Abstract

Populytics, an independent subsidiary of the Lehigh Valley Health Network offers various Population Health Management and Advanced Analytic services. Among these services is the Chronic Condition Management Health Coaching Program for members of the Lehigh Valley Health Network's self insured plan, Choice Plus. This Health Coaching program is free to all Choice Plus members, including spouses and dependents of Network employees, identified through predictive modeling tools as low, moderate, or high risk for one or more of eight chronic conditions, including asthma, chronic obstructive pulmonary disease, hyperlipidemia, hypertension, obesity, vascular disease, and diabetes. Registered Nurse (RN) Coaches …

Improving Patient Outcomes By Using Teleid Consultation Services, Kimberly Pianucci, Jessica Hartnet, Sharon Kromer

Research Scholars Poster Presentation

Abstract

The Lehigh Valley Health Network began TeleID consultative services in February 2011, with the goal of providing infectious disease services to patients at remote facilities through the use of teleconferencing equipment. The effects of this service on patient outcomes are not yet known as a result of this service being so contemporary. The literature review carried out previous to the start of the project presented extremely limited scholarly information or evidence-based research on Telehealth services for infectious disease. The study is a retrospective cohort study, reviewing the charts of patients from Blue Mountain Health Systems (BMHS), Greater Hazleton Health …

Low Zinc Levels Is Associated With Increased Inflammatory Activity But Not With Atherosclerosis, Arteriosclerosis Or Endothelial Dysfunction Among The Very Elderly, Ehimen Aneni, Khurram Nasir

All Publications

BACKGROUND:

Reduced zinc intake has been related to atherogenesis and arteriosclerosis. We verified this assumption in very old individuals, which are particularly prone to both zinc deficiency and structural and functional changes in the arterial wall.

METHODS:

Subjects (n = 201, 80-102 years) with uneventful cardiovascular history and who were not in use of anti-inflammatory treatments in the last 30-days were enrolled. Daily intake of zinc, lipid profile, plasma C-reactive protein (CRP), plasma zinc, flow-mediated dilation (FMD), carotid ultrasonography and cardiac computed tomography were obtained. Young's Elastic Modulus, Stiffness Index and Artery Compliance were calculated.

RESULTS:

There was no significant …

Tuberculosis (Tb) Research In India During 2004-2013: A Bibliometric Analysis, Rabindra K. Maharana, Ashok Kumar Das, Jayanta Kumar Sahu

Library Philosophy and Practice (e-journal)

The present study is a bibliometric analysis of all Indian tuberculosis publications over the past 10 years, in the national/ international journals of repute. Utilizing the Scopus database, 7945 documents of Indian researcher’s publications data on tuberculosis research were used for the study, with an average of 794-795 documents per year and majority of them were research articles (76.56%). International Journal of Tuberculosis and Lung Disease; All India Institute of Medical Sciences (AIIMS) and D. Sriram were the most favoured research journal; major contributing organization/ institution and most prolific contributor. Article, Human and Humans were the most frequently used keywords.

The Semen Microbiome And Its Relationship With Local Immunology And Viral Load In Hiv Infection, Cindy M. Liu, Brendan J.W. Osborne, Bruce A. Hungate, Kamnoosh Shahabi, Sanja Huibner, Richard Lester, Michael G. Dwan, Colin Kovacs, Tania L. Contente-Cuomo, Erika Benko, Maliha Aziz, Lance B. Price

Environmental and Occupational Health Faculty Publications

Semen is a major vector for HIV transmission, but the semen HIV RNA viral load (VL) only correlates moderately with the blood VL. Viral shedding can be enhanced by genital infections and associated inflammation, but it can also occur in the absence of classical pathogens. Thus, we hypothesized that a dysregulated semen microbiome correlates with local HIV shedding. We analyzed semen samples from 49 men who have sex with men (MSM), including 22 HIV-uninfected and 27 HIV-infected men, at baseline and after starting antiretroviral therapy (ART) using 16S rRNA gene-based pyrosequencing and quantitative PCR. We studied the relationship of semen …

Maternal And Congenital Toxoplasmosis, Currently Available And Novel Therapies In Horizon, Helieh S. Oz

Internal Medicine Faculty Publications

Over one billion people worldwide are predicted to harbor Toxoplasma infection frequently with unknown lifelong health consequences. Toxoplasmosis is an important cause of foodborne, inflammatory illnesses, as well as congenital abnormalities. Ubiquitous Toxoplasma has a unique tropism for central nervous system with a mind-bugging effect and is transmitted sexually through semen. Currently available therapies are ineffective for persistent chronic disease and congenital toxoplasmosis or have severe side effects which may result in life-threatening complications. There is an urgent need for safe and effective therapies to eliminate or treat this cosmopolitan infectious and inflammatory disease. This investigation discusses pathogenesis of maternal …

Review Of Microbially Induced Corrosion And Comments On Needs Related To Testing Procedures, Mitchell House, W. J. Weiss

International Conference on Durability of Concrete Structures

Concrete is the most widely used material for the construction of the wastewater collection, storage, and treatment infrastructure. The chemical and physical characteristics of hydrated Portland cement may make it susceptible to degradation under highly acidic conditions. As a result, some concrete wastewater infrastructure may be susceptible to a multistage degradation process known as microbially induced corrosion (MIC). MIC begins with the production of aqueous hydrogen sulfide (H2S(aq)) by anaerobic sulfate-reducing bacteria present below the waterline. H2S(aq) partitions to the gas phase where it is oxidized to sulfuric acid by the aerobic sulfur-oxidizing bacteria Thiobacillus that resides on concrete surfaces …

Emotion Regulation To Facilitate The Process And Products Of Learning In Online Learning Environments, Amber Chauncey Strain

Electronic Theses and Dissertations Archive

Emotional experiences occur often during online learning and need to be successfully regulated. In this dissertation, three interventions were tested to gauge their effects on engagement and performance. These interventions used or combined elements of cognitive reappraisal and situated context construction. Ethnically diverse adult learners ranging from 18 to 68 years of age (N = 209) used one of these strategies or no strategy (control) in an online learning environment. It was predicted that participants who used these interventions would experience more engagement and higher learning outcomes than a control condition. It was also predicted that the combined use of …

Pregnancy Outcomes In Women With Homozygous Beta Thalassaemia : A Single-Centre Experience From Oman, Nihal Al-Riyami, Maha Al-Khaduri, Shahina

Sultan Qaboos University Medical Journal

Objectives: Pregnancy in women with homozygous beta thalassaemia (HBT) carries a high risk to both the mother and fetus. The aim of this study was to investigate pregnancy outcomes among this group at a single tertiary centre. Methods: This retrospective descriptive study was conducted between January 2006 and December 2012 on all women with HBT who received prenatal care and subsequently delivered at Sultan Qaboos University Hospital, Muscat, Oman. Women who delivered elsewhere and women with the beta thalassaemia trait were excluded. Results: Ten women with HBT were studied with a total of 15 pregnancies and 14 live births. The …

Compliance With The National Palestinian Infection Prevention And Control Protocol At Governmental Paediatric Hospitals In Gaza Governorates, Ashraf Eljedi, Shareef Dalo

Sultan Qaboos University Medical Journal

Objectives: Nosocomial infections are a significant burden for both patients and the healthcare system. For this reason, infection prevention and control (IPC) practices are extremely important. The Palestinian Ministry of Health adopted the national IPC Protocol in 2004. This study aimed to assess the compliance of healthcare providers (HCPs) with the Protocol in three governmental paediatric hospitals in Gaza governorates. Methods: This descriptive cross-sectional study was conducted from February to November 2010. Data were collected from a sample of doctors, nurses and physiotherapists (N = 334) using a self-administered questionnaire and observation checklists to record HCP practices and assess the …