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The Montclarion, September 18, 2014, The Montclarion

The Montclarion

Student Newspaper of Montclair State University

Treating Cocaine Dependency With Psychopharmacotherapy And Behavioral Therapy, Robyn Liebman

e-Research: A Journal of Undergraduate Work

Cocaine is an addictive drug that affects more than 14 million people globally, according to the United Nations. This paper is a conceptual meta-analysis of numerous studies that tested the effects of psychopharmacological therapy along with behavioral therapy in the treatment of cocaine addiction. It is hypothesized that cocaine dependent individuals treated with a combination of psychopharmacological and behavioral therapies will be less likely to use cocaine. Measurements of cocaine use throughout the experiments were generally assessed by urine screenings. Results indicate that there is more evidence that a combination of psychopharmacological and behavioral therapies will reduce cocaine use. There …

Bridging The Food Gap: Addressing The Feasibility And Applicability Of Three Key Traditionally Western Food Preservation Techniques To Improving Household Food Security And Reducing Malnutrition In Uganda., Eva K. Baguma

Capstone Collection

Food wastage is the leading cause of food insecurity and malnutrition in the world today. A huge amount of food gets wasted along the food supply chain from the time it is harvested to the time it gets to our plates. A significant amount of the food wasted happens in the home as well as on farms, in restaurants and supermarkets across the globe.

In Sub-Saharan Africa, many families and communities are facing severe food shortages due to lack of electricity for refrigeration, poor storage facilities and limited access to markets.

However for many centuries, different cultures around the world …

Ada News - 09/15/2014, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

Role Of Adaptor Trfa And Clppc In Controlling Levels Of Ssra-Tagged Proteins And Antitoxins In Staphylococcus Aureus, Niles P. Donegan, Jonathan S. Marvin, Ambrose L. Cheung

Dartmouth Scholarship

Staphylococcus aureus responds to changing extracellular environments in part by adjusting its proteome through alterations of transcriptional priorities and selective degradation of the preexisting pool of proteins. In Bacillus subtilis, the proteolytic adaptor protein MecA has been shown to play a role in assisting with the proteolytic degradation of proteins involved in competence and the oxidative stress response. However, the targets of TrfA, the MecA homolog in S. aureus, have not been well characterized. In this work, we investigated how TrfA assists chaperones and proteases to regulate the proteolysis of several classes of proteins in S. aureus. …

The Capus Project-Innovative Solutions For Hiv/Aids Linkage To Care, Melanie Gwynn, Jamila Ealey, Kate Racoff Musgrove

9th Annual Rural HIV Research & Training Conference (2014-2019) (Archived)

“The CAPUS Project-Innovative Solutions for HIV/AIDS Linkage to Care”

Objectives: 1) Expand knowledge of the current linkage to care landscape within Georgia; 2) Identify essential components of the Resource Hub to enhance linkage to care efforts throughout Georgia; and 3)Promote effective use of the Resource Hub to facilitate HIV/AIDS linkage to care within highly impacted communities

Lack Of Awareness Of Human Immunodeficiency Virus (Hiv) Infection: Problems And Solutions With Self-Reported Hiv Serostatus Of Men Who Have Sex With Men, Travis H. Sanchez, Colleen F. Kelley, Eli Rosenberg, Nicole Luisi, Brandon O'Hara, Rodriques Lambert, Raphael Coleman, Paula M. Frew, Laura F. Salazar, Sijia Tao, William Clarke, Carlos Del Rio, Patrick S. Sullivan

Environmental & Global Health Faculty Research

Background. Lack of human immunodeficiency virus (HIV) infection awareness may be a driver of racial disparities in HIV infection among men who have sex with men (MSM). Lack of awareness is typically measured by comparing HIV test result to self-reported HIV status. This measure may be subject to reporting bias and alternatives are needed.Methods. The InvolveMENt study examined HIV disparities between black and white MSM from Atlanta. Among HIV-positive participants who did not report knowing they were positive, we examined other measures of awareness: … See full text for complete abstract.

Simulation Of Social Networks To Maximize The Prevention And Treatment Of Alcohol Use Disorders, Kevin Hallgren

Psychology ETDs

Introduction: Previous studies have found associations between alcohol use and having heavy-drinking social networks. This association is thought to be caused by (1) social influence, where ones social network influences his or her drinking, and (2) social selection, where an individual forms relationships with individuals who drink at similar levels. These processes are reciprocal and, when acting simultaneously, create a feedback loop with non-linear dynamics. Computer simulations have allowed complex systems to be modeled in many scientific fields; however, this method has not yet been used to study the dynamic associations between social networks and alcohol use. Method: The present …

Virus Sharing, Genetic Sequencing, And Global Health Security, Lawrence O. Gostin, Alexandra Phelan, Michael A. Stoto, John D. Kraemer, K. Srinath Reddy

Georgetown Law Faculty Publications and Other Works

The WHO’s Pandemic Influenza Preparedness (PIP) Framework was a milestone global agreement designed to promote the international sharing of biological samples to develop vaccines, while that ensuring poorer countries would have access to those vaccines. Since the PIP Framework was negotiated, scientists have developed the capacity to use genetic sequencing data (GSD) to develop synthetic viruses rapidly for product development of life-saving technologies in a time-sensitive global emergency—threatening to unravel the Framework. Access to GSD may also have major implications for biosecurity, biosafety, and intellectual property (IP).

By rendering the physical transfer of viruses antiquated, GSD may also undermine the …

Socio-Economic And Demographic Predictors Of Mammography And Pap Smear Screening In Us Women, Curtis Christensen

Economics ETDs

In 2010, 240,000 women were diagnosed with breast cancer and 16,000 women were diagnosed with cervical cancer (www.seer.cancer.gov). In spite of technological advances and increases in education regarding cancer screening, healthcare costs are still on the rise and disagreement still exists between physicians who create guidelines and policy makers (Woloshin, 2000). This project examines cancer screening and examines socio-economic and demographic predictors for usage of preventative screening measures. This project also examines disparities in the current screening process. Data from the National Health Interview Survey (NHIS) from 1987 and 2010 were used to compare differences across time. The results indicate …

Innovative Sexually Transmitted Infection Prevention-Intervention For African-American Adolescent Girls, Brialle D. Ringer

McNair Scholars Research Journal

The purpose of this study is to determine whether implementation of an innovative STI prevention intervention design affects participants’ knowledge of sexually transmitted infections and sexual self-efficacy. The population this research focuses on is African-American adolescent girls. The participants included in this study are aged 13-19. This particular population is disproportionately infected by sexually transmitted diseases, so it is vital that intervention programs be tailored to fit their culture and gender-specific needs in order to achieve maximum results. However, current interventions for African-American girls could be improved. The researcher has designed an innovative STI prevention intervention that draws from current, …

Differential Spatial Repositioning Of Activated Genes In Biomphalaria Glabrata Snails Infected With Schistosoma Mansoni, Halime D. Arican-Goktas, Wannaporn Ittiprasert, Joanna M. Bridger, Matty Knight

Microbiology, Immunology, and Tropical Medicine Faculty Publications

Schistosomiasis is an infectious disease infecting mammals as the definitive host and fresh water snails as the intermediate host. Understanding the molecular and biochemical relationship between the causative schistosome parasite and its hosts will be key to understanding and ultimately treating and/or eradicating the disease. There is increasing evidence that pathogens that have co-evolved with their hosts can manipulate their hosts' behaviour at various levels to augment an infection. Bacteria, for example, can induce beneficial chromatin remodelling of the host genome. We have previously shown in vitro thatBiomphalaria glabrata embryonic cells co-cultured with schistosome miracidia display genes changing their …

The Spatial Dynamics Of Dengue Virus In Kamphaeng Phet, Thailand, Piraya Bhoomiboonchoo, Robert V. Gibbons, Angkana Huang, In-Kyu Yoon, Darunee Buddhari, Ananda Nisalak, Natkamol Chansatiporn, Mathuros Thipayamongkolgul, Siripen Kalanarooj, Timothy Endy, Alan Rothman, Anon Srikiatkhachorn, Sharone Green, Mammen P. Mammen, Derek A. Cummings, Henrik Salje

Institute for Immunology and Informatics Faculty Publications

Background: Dengue is endemic to the rural province of Kamphaeng Phet, Northern Thailand. A decade of prospective cohort studies has provided important insights into the dengue viruses and their generated disease. However, as elsewhere, spatial dynamics of the pathogen remain poorly understood. In particular, the spatial scale of transmission and the scale of clustering are poorly characterized. This information is critical for effective deployment of spatially targeted interventions and for understanding the mechanisms that drive the dispersal of the virus.

Methodology/Principal Findings: We geocoded the home locations of 4,768 confirmed dengue cases admitted to the main hospital in Kamphaeng Phet …

Space Radiation: The Number One Risk To Astronaut Health Beyond Low Earth Orbit, Jeffery C. Chancellor, Graham B.I. Scott, Jeffrey P. Sutton

Faculty Publications

Projecting a vision for space radiobiological research necessitates understanding the nature of the space radiation environment and how radiation risks influence mission planning, timelines and operational decisions. Exposure to space radiation increases the risks of astronauts developing cancer, experiencing central nervous system (CNS) decrements, exhibiting degenerative tissue effects or developing acute radiation syndrome. One or more of these deleterious health effects could develop during future multi-year space exploration missions beyond low Earth orbit (LEO). Shielding is an effective countermeasure against solar particle events (SPEs), but is ineffective in protecting crew members from the biological impacts of fast moving, highly-charged galactic …

The Cowl - V.79 - N.2 - Sep 11, 2014

The Cowl

The Cowl - student newspaper of Providence College. Vol 79 - No. 2 - September 11, 2014. 21 pages.

Assessing Climate Variability Effects On Dengue Incidence In San Juan, Puerto Rico, Pablo Méndez-Lázaro, Frank E. Muller-Karger, Daniel Otis, Matthew J Mccarthy, Marisol Peña-Orellana

Marine Science Faculty Publications

We test the hypothesis that climate and environmental conditions are becoming favorable for dengue transmission in San Juan, Puerto Rico. Sea Level Pressure (SLP), Mean Sea Level (MSL), Wind, Sea Surface Temperature (SST), Air Surface Temperature (AST), Rainfall, and confirmed dengue cases were analyzed. We evaluated the dengue incidence and environmental data with Principal Component Analysis, Pearson correlation coefficient, Mann-Kendall trend test and logistic regressions. Results indicated that dry days are increasing and wet days are decreasing. MSL is increasing, posing higher risk of dengue as the perimeter of the San Juan Bay estuary expands and shorelines move inland. Warming …

Political Influence Associates With Cortisol And Health Among Egalitarian Forager-Farmers, Christopher Von Rueden, Benjamin C. Trumble, Melissa Emery Thompson, Jonathan Stieglitz, Paul L. Hooper, Aaron D. Blackwell, Hillard Kaplan, Michael Gurven

ESI Publications

Background and objectives: Low social status increases risk of disease due, in part, to the psychosocial stress that accompanies feeling subordinate or poor. Previous studies report that chronic stress and chronically elevated cortisol can impair cardiovascular and immune function. We test whether lower status is more benign in small-scale, relatively egalitarian societies, where leaders lack coercive authority and there is minimal material wealth to contest.

Methodology: Among Tsimane’ forager-horticulturalists of lowland Bolivia, we compare informal political influence among men with urinary cortisol, immune activation (innate and acquired), and morbidity as assessed during routine medical exams.

Results: After …

Wound Healing: Biologics, Skin Substitutes, Biomembranes And Scaffolds, Krishna S. Vyas, Henry C. Vasconez

Surgery Faculty Publications

This review will explore the latest advancements spanning several facets of wound healing, including biologics, skin substitutes, biomembranes and scaffolds.

Gene Expression Profiling Identifies Irf4-Associated Molecular Signatures In Hematological Malignancies, Ling Wang, Zhi Q. Yao, Jonathan P. Moorman, Yanji Xu, Shunbin Ning

ETSU Faculty Works

The lymphocyte-specific transcription factor Interferon (IFN) Regulatory Factor 4 (IRF4) is implicated in certain types of lymphoid and myeloid malignancies. However, the molecular mechanisms underlying its interactions with these malignancies are largely unknown. In this study, we have first profiled molecular signatures associated with IRF4 expression in associated cancers, by analyzing existing gene expression profiling datasets. Our results show that IRF4 is overexpressed in melanoma, in addition to previously reported contexts including leukemia, myeloma, and lymphoma, and that IRF4 is associated with a unique gene expression pattern in each context. A pool of important genes involved in B-cell development, oncogenesis, …

Possible Respiratory Virus Affecting Children Spreads To Alabama, Staff

Browse All News

No abstract provided.

Who's Virus Is It Anyway? How The World Health Organization Can Protect Against Claims Of "Viral Sovereignty", Jason Carter

Georgia Journal of International & Comparative Law

No abstract provided.

Prospectus, September 3, 2014, Peter Cowley, Scott Barnes, Austin Jacobson

Prospectus 2014

SMOKING TO BE BANNED ON PARKLAND CAMPUS, Study Yields Full Genetic Snapshot of Ebola Virus, Diverse Local Agriculture Provides Career Options for Students, Annual Sweetcorn Festival Returns to Urbana, Pediatricians Recommended More Sleep and Later School Start Times for Teens, Back-to-School Tips for All, Reviews of New Pop Music Releases

High Mrsa Carriage Rate Among Nursing Microbiology Students, Alan Lee Gillen, Whitney O. Daycock, Andrew Serafin

Faculty Publications and Presentations

Staphylococcus aureus is a common cause of disease, particularly in colonized persons. Although methicillin-resistant S. aureus (MRSA) infections have become increasingly reported, populationbased studies of students preparing for the health professions having S. aureus and MRSA colonization are lacking. We have found that students in microbiology classes having more contact with individuals in a healthcare setting are more likely to carry MRSA in their nares and axilla. The classes who had the highest rate of MRSA carriage during the school year, 2013-2014, were those with nursing students, who had a greater exposure to clinical settings and nursing homes. The class …

Alabama Children Are Latest Believed To Be Hit By Rare Respiratory Virus, Staff

Browse All News

No abstract provided.

A Rational Framework For Evaluating The Next Generation Of Vaccines Against Mycobacterium Avium Subspecies Paratuberculosis, John P. Bannantine, Murray E. Hines Ii, Luiz E. Bermudez, Adel M. Talaat, Srinand Sreevatsan, Judith R. Stabel, Yung-Fu Chang, Paul M. Coussens, Raúl G. Barletta, William C. Davis, Desmond M. Collins, Yrjö T. Gröhn, Vivek Kapur

School of Veterinary and Biomedical Sciences: Faculty Publications

Since the early 1980s, several investigations have focused on developing a vaccine against Mycobacterium avium subspecies paratuberculosis (MAP), the causative agent of Johne's disease in cattle and sheep. These studies used whole-cell inactived vaccines that have proven useful in limiting disease progression, but have not prevented infection. In contrast, modified live vaccines that invoke a Th1 type immune response, may improve protection against infection. Spurred by recent advances in the ability to create defined knockouts in MAP, several independent laboratories have developed modified live vaccine candidates by transcriptional mutation of virulence and metablolic genes in MAP. In order to accelerate …

The Statesman, V. 58, I. 03, Stony Brook University

Stony Brook Statesman-Sucolian

v. 58, i. 03

Gene Expression Analysis Of Bovine Peripheral Blood Mononuclear Cells In Response To Adenovirus-Vectored Foot-And-Mouth Disease Vaccine, Frank Zappulla

Master's Theses

Foot-and-mouth disease virus (FMDV) gives rise to a highly contagious and economically important disease of cloven-hooved animals. Vaccination reduces the economic impact by inducing serotype-specific protection. Recently, a replication-defective adenovirus-vectored foot-and-mouth disease (FMD) subunit vaccine was developed and licensed. Serum virus neutralization (SVN) titer ≥1.5 to FMDV is the best predictor of vaccine-induced protection. However, protection does not always correlate with the presence of neutralizing antibodies. For example, some animals with high SVN titer develop signs of disease, and conversely, some animals with negligible SVN titer are protected. Categorizing cattle on the parameters of seroconversion and protection status yields four …

The Immunological Effectiveness Of Some Common Plants, Anwar I. S. Al-Assaf, Zahraa H. M. Kadri

Baghdad Science Journal

Three plant species were picked randomly and their alcoholic extracts have been screened to know their effects on the phagocytic capability and intracellular killing of yeast by human peripheral macrophages. Macrophage cultures were incubated with different concentration of each plant extract: for 15 min., 30 min .and 45 min. The phagocytes activity in Iresine herbstii extract was significantly (p≤0.05) increased with increasing dose and time of incubation. In Mentha piperita extract, increasing in dose and time of incubation leads to elevate phagocytic capbility, especially in the dose of 20% and 25% of plant extract, perhaps because the antimicrobial and antiviral …

Seasonality Of Birth Outcomes In Rural Sarlahi District, Nepal: A Population-Based Prospective Cohort, Michelle M. Hughes, Joanne Katz, Luke C. Mullany, Subarna K. Khatry, Steven C. Leclerq, Gary L. Darmstadt, James M. Tielsch

Global Health Faculty Publications

Background

While seasonality of birth outcomes has been documented in a variety of settings, data from rural South Asia are lacking. We report a descriptive study of the seasonality of prematurity, low birth weight, small for gestational age, neonatal deaths, and stillbirths in the plains of Nepal.

Methods

Using data collected prospectively during a randomized controlled trial of neonatal skin and umbilical cord cleansing with chlorhexidine, we analyzed a cohort of 23,662 babies born between September 2002 and January 2006. Project workers collected data on birth outcomes at the infant’s household. Supplemental data from other studies conducted at the same …

2014-September-05-Kruppa, Nih Grant, University Marketing And Communications, East Tennessee State University

ETSU News

No abstract provided.