Digital Commons Network^™

Pathogenic Adaptations To Host-Derived Antibacterial Copper, Kaveri S. Chaturvedi, Jeffrey P. Henderson

Open Access Publications

No abstract provided.

Clinical Implications For Patients Treated Inappropriately For Community-Acquired Pneumonia In The Emergency Department, Scott T. Micek, Adam Lang, Brian M. Fuller, Nicholas B. Hampton, Marin H. Kollef

Open Access Publications

No abstract provided.

Conference Highlights Of The 16th International Conference On Human Retrovirology: Htlv And Related Retroviruses, 26–30 June 2013, Montreal, Canada, Benoit Barbeau, John Hiscott, Ali Bazarbachi, Edgar Carvalho, Kathryn Jones, Fabiola Martin, Masao Matsuoka, Edward L. Murphy, Lee Ratner, William M. Switzer, Toshiki Watanabe

Open Access Publications

No abstract provided.

The Changing Immune System In Sepsis: Is Individualized Immuno-Modulatory Therapy The Answer?, Jonathan S. Boomer, Jonathan M. Green, Richard S. Hotchkiss

Open Access Publications

No abstract provided.

Health Seeking Behaviour In Malaria Treatment By The Fishing Community Of Rusinga Island, Western Kenya, Jacqueline E. Oduke

All Master’s Theses

Literature on health and diseases indicate that people perceive diseases variously. People develop their own views and beliefs about the causes, symptoms, modes of transmission and therapy choices, which then influence their health seeking behaviour. The main objective of this study was to explore health seeking behaviour in relation to malaria among the fishermen on Rusinga Island on Lake Victoria Kenya. This study which focused on the fishermen on Rusinga Island on Lake Victoria Kenya sought to establish the behavioural practices that are thought to predispose fishermen to malaria, the social cultural factors influencing their choices of therapy and the …

Human Cytomegalovirus Pul79 Is An Elongation Factor Of Rna Polymerase Ii For Viral Gene Transcription, Yi-Chieh Perng, Jessica A. Campbell, Deborah J. Lenschow, Dong Yu

Open Access Publications

No abstract provided.

Training Needs And Supports For Evidence-Based Decision Making Among The Public Health Workforce In The United States, Rebekah R. Jacob, Elizabeth A. Baker, Peg Allen, Elizabeth A. Dodson, Kathleen Duggan, Robert Fields, Sonia Sequeira, Ross C. Brownson

Open Access Publications

No abstract provided.

Treatment Of Gram - Positive Infections In Critically Ill Patients, Cristina Vazquez-Guillamet, Marin H. Kollef

Open Access Publications

No abstract provided.

A Novel Genetic Locus Linked To Pro-Inflammatory Cytokines After Virulent H5n1 Virus Infection In Mice, Adrianus C.M. Boon, Robert W. Williams, David S. Sinasac, Richard J. Webby

Open Access Publications

No abstract provided.

How To Avoid Microaspiration? A Key Element For The Prevention Of Ventilator-Associated Pneumonia In Intubated Icu Patients, Stijn I. Blot, Jan Poelaert, Marin Kollef

Open Access Publications

No abstract provided.

Common Exposure To Stl Polyomavirus During Childhood, Efrem S. Lim, Natalie M. Meinerz, Blake Primi, David Wang, Robert L. Garcea

Open Access Publications

No abstract provided.

Genomic Epidemiology Of Salmonella Enterica Serotype Enteritidis Based On Population Structure Of Prevalent Lineages, Xiangyu Deng, Prerak T. Desai, Henk C. Den Bakker, Matthew Mikoleit, Beth Tolar, Eija Trees, Rene S. Hendriksen, Jonathan G. Frye, Steffen Porwollik, Bart C. Weimer, Martin Wiedmann, George M. Weinstock, Patricia I. Fields, Michael Mcclelland

Open Access Publications

No abstract provided.

Geographic Separation Of Domestic And Wild Strains Of Toxoplasma Gondii In French Guiana Correlates With A Monomorphic Version Of Chromosome1a, Asis Khan, Daniel Ajzenberg, Aurelien Mercier, Magalie Demar, Stephane Simon, Marie Laure Darde, Qiuling Wang, Shiv Kumar Verma, Benjamin M. Rosenthal, Jitender P. Dubey, L. David Sibley

Open Access Publications

No abstract provided.

Multi-Drug Resistance, Inappropriate Initial Antibiotic Therapy And Mortality In Gram-Negative Severe Sepsis And Septic Shock: A Retrospective Cohort Study, Marya D. Zilberberg, Andrew F. Shorr, Scott T. Micek, Cristina Vazquez-Guillamet, Marin H. Kollef

Open Access Publications

No abstract provided.

A 2-Pyridone-Amide Inhibitor Targets The Glucose Metabolism Pathway Of Chlamydia Trachomatis, Patrik Engstrom, K. Syam Krishnan, Bidong D. Ngyuen, Erik Chorell, Johan Normark, Jim Silver, Robert J. Bastidas, Matthew D. Welch, Scott J. Hultgren, Hans Wolf-Watz, Raphael H. Valdivia, Fredrik Almqvist, Sven Bergstrom

Open Access Publications

No abstract provided.

Attributable Inpatient Costs Of Recurrent Clostridium Difficile Infections, Erik R. Dubberke, Eric Schaefer, Kimberly A. Reske, Marya Zilberberg, Christopher S. Hollenbeak, Margaret A. Olsen

Open Access Publications

No abstract provided.

Dendritic Cells In Dengue Virus Infection: Targets Of Virus Replication And Mediators Of Immunity, Michael A. Schmid, Michael S. Diamond, Eva Harris

Open Access Publications

No abstract provided.

Phylogenomics And The Dynamic Genome Evolution Of The Genus Streptococcus, Vincent P. Richards, Sara R. Palmer, Paulina D. Pavinski Bitar, Xiang Qin, George M. Weinstock, Sarah K. Highlander, Christopher D. Town, Robert A. Burne, Michael J. Stanhope

Open Access Publications

No abstract provided.

Fruits Of Virus Discovery: New Pathogens And New Experimental Models, David Wang

Open Access Publications

No abstract provided.

Short Communication: The Veterans Aging Cohort Study Index Is An Effective Tool To Assess Baseline Frailty Status In A Contemporary Cohort Of Hiv-Infected Persons, Gerome V. Escota, Pragna Patel, John T. Brooks, Tim Bush, Lois Conley, Jason Baker, Erna M. Kojic, John Hammer, Nur F. Önen

Open Access Publications

No abstract provided.

Policy Evidence Assessment Report: Community Health Worker Policy Components, Center For Public Health Systems Science

Center for Public Health Systems Science

This Policy Evidence Assessment Report from the National Center for Chronic Disease Prevention and Health Promotion, Division of Heart Disease and Stroke Prevention, summarizes the evidence base for components of Community Health Worker Policy. Many of these components are elements of successful CHW programs, which have implications for policy development, and some of these components can be found in state law.

Wild Minds: Adventure Therapy, Ecopsychology, And The Rewilding Of Humanity, William Hafford

Antioch University Dissertations & Theses

This dissertation sits at the intersection of ecopsychology and adventure therapy. It explores humankind’s relationship with nature and wilderness, as well as the co-evolution of ecopsychology and adventure therapy within the field of psychology. The primary aim of this dissertation is to lay the groundwork for rewilding humanity with the specific focus of providing practitioners with a compelling case for intentionally integrating ecopsychology with their adventure therapy practice. This theoretical paper concludes with a suggested expansion of ethics and competencies for adventure therapists.

The Relationship Between Select Demographic Characteristics And Body Mass Index Among Native Hawaiian And Other Pacific Islander Caregiving Adults, Jane Lassetter Phd, Rn, Lauren Clark Phd, Rn, Faan, Sharla E. Morgan Fnp, Lora Beth Brown Phd, Gwen Vanservellen Phd, Rn, Faan, Katrina Duncan Fnp, Betsy S. Hopkins

Faculty Publications

Native Hawaiian or other Pacific Islanders (NHOPIs) are people with genetic origins in Hawaii, Samoa, or other Pacific Islands (Hixson, Hepler, & Kim, 2012). NHOPI prevalence of overweight or obesity is among the highest in the world. Nauru, a Pacific Island nation, is considered the most obese country in the world with an overweight and obesity prevalence of 93% (WHO, 2011). Hawaii’s overall prevalence of overweight or obesity is 52.1%, but the prevalence for Native Hawaiian residents is 69.6% (Hawaii Department of Health, 2011). Inasmuch as NHOPIs are one of the fastest growing ethnic groups in the U.S. (Hixson et …

Multipolarity, Intellectual Property, And The Internationalization Of Public Health Law, Sam Halabi

Articles, Chapters in Books and Other Contributions to Scholarly Works

This Article critically examines the proliferation of international legal agreements addressing global health threats like the outbreak of infectious diseases, tobacco use and lack of access to affordable medicines. The conventional wisdom behind this trend is that a global normative shift has occurred which has caused states to regard health as “special” and less subject to the normal rules of international law making because health threats endanger all of humanity. This Article challenges that thesis, arguing that at the same time the number and scope of international health law treaties has grown, developed states have subordinated health law to intellectual …

Parameterization Of Pharmaceutical Emissions And Removal Rates For Use In Uk Predictive Exposure Models: Steroid Estrogens As A Case Study, Jd Heffley, Sdw Comber, Bw Wheeler, Ch Redshaw

School of Geography, Earth and Environmental Sciences

Using local population characteristics and prescription data to predict pharmaceutical concentrations in sewage influent and effluent.

Parameterization Of Pharmaceutical Emissions And Removal Rates For Use In Uk Predictive Exposure Models: Steroid Estrogens As A Case Study., J. D. Heffley, S. D.W. Comber, B. W. Wheeler, C. H. Redshaw

School of Geography, Earth and Environmental Sciences

Newly available prescription data has been used along with census data to develop a localised method for predicting pharmaceutical concentrations in sewage influent and effluent for England, and applied to a case study: the steroid estrogens estrone, 17β-estradiol, and 17α-ethinylestradiol in a selected catchment. The prescription data allows calculation of the mass consumed of synthetic estrogens, while use of highly localised census data improves predictions of naturally excreted estrogens by accounting for regional variations in population demographics. This serves two key purposes; to increase the accuracy of predictions in general, and to call attention to the need for more accurate …

Dynamic Social Networks In Guppies (Poecilia Reticulata), Alexander D.M. Wilson, S Krause, Richard James, Darren P. Croft, Indar W. Ramnarine, Karoline K. Borner, Romain J.G. Clement, J Krause

School of Biological and Marine Sciences

No abstract provided.

Receptor Of Advanced Glycation Endproducts (Rage) Is Positively Correlated With Tumor Necrosis Factor-Α In Adolescents With Obesity, Tasnim Rahman, Daniel H. Conrad, Anshu Gupta

UROP Posters

Introduction: Obesity in childhood is associated with an increased prevalence of diabetes and other traditional cardiometabolic risk factors, suggesting an epidemic of premature cardiovascular disease among today’s youth. Glycotoxins, known as advanced glycationend products (AGE’s), activating via the membrane-bound receptors (mRAGE), have been implicated in the pathophysiology of inflammation, (increased tumor necrosis factor-α [TNF-α ]), insulin resistance and vascular dysfunction in adults, but the role of RAGE in the early stages of metabolic disorders is unknown. In this study, we assessed relationship of cardiometabolicrisk factors, mRNA expression of TNF-α and RAGE in peripheral monocytes in adolescents with obesity.

Methods: Thirty …

Integrating Phage Therapy Into Western Medicine, Jacob B. Jaminet

UROP Posters

The World Health Organization has described the rise of antibiotic use as a “global heath security emergency” (who.int). With the growing concern about antibiotic resistant bacteria, there has been an increased interest in bacteriophages. Bacteriophages are high-specific viruses that only infect bacteria. The use of bacteriophages medicinally to treat bacteria is called phage therapy. Research in phage therapy gained momentum until the introduction of antibiotics. While the USA and other Western countries accepted antibiotics, the Soviet Union and their satellite nations still continued to research phages. Since the funding for research was supplied by the Soviet military, the results of …

Moving Beyond Too Little, Too Late: Managing Emerging Infectious Diseases In Wild Populations Requires International Policy And Partnerships, Jamie Voyles, A. Marm Kilpatrick, James P. Collins, Matthew C. Fisher, Winifred F. Frick, Hamish Mccallum, Craig K.R. Willis, David S. Blehert, Kris A. Murray, Robert Puschendorf, Erica Bree Rosenblum, Benjamin M. Bolker, Tina L. Cheng, Kate E. Langwig, Daniel L. Lindner, Mary Toothman, Mark Q. Wilber, Cheryl J. Briggs

School of Biological and Marine Sciences

Emerging infectious diseases (EIDs) are on the rise due to multiple factors, including human facilitated movement of pathogens, broad-scale landscape changes, and perturbations to ecological systems (Jones et al. 2008; Fisher et al. 2012). Epidemics in wildlife are problematic because they can lead to pathogen spillover to new host organisms, erode biodiversity and threaten ecosystems that sustain human societies (Fisher et al. 2012; Kilpatrick 2011). There have been recent calls for large-scale research approaches to combat the threats EIDs pose to wildlife (Sleeman 2013). While it is true that developing new analytical models, diagnostic assays and molecular tools will significantly …