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Effects Of Virus On Plant Fecundity And Population Dynamics, Holly R. Prendeville, Brigitte Tenhumberg, Diana Pilson

Brigitte Tenhumberg Papers

Microorganisms are ubiquitous and thought to regulate host populations. Although microorganisms can be pathogenic and affect components of fitness, few studies have examined their effects on wild plant populations. As individual traits might not contribute equally to changes in population growth rate, it is essential to examine the entire life cycle to determine how microorganisms affect host population dynamics. In this study, we used data from common garden experiments with plants from three Cucurbita pepo populations exposed to three virus treatments. These data were used to parameterize a deterministic matrix model, which allowed us to estimate the effect of virus …

Redescription Of Oligacanthorhynchus Microcephalus (Rudolphi, 1819) Schmidt 1972 (Syn. Oligacanthorhynchus Tortuosa (Leidy, 1850) Schmidt 1972) (Acanthocephala: Oligacanthorhynchidae), Dennis J. Richardson, Scott Lyell Gardner, Jonathan W. Allen Jr.

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Oligacanthorhynchus microcephalus (Rudolphi, 1819) Schmidt, 1972 was originally described from the philander opossum Caluromys philander from Brazil. Oligacanthorhynchus tortuosa (Leidy, 1850) Schmidt, 1972 was originally described from the Virginia opossum (Didelphis virginiana) in North America. Six years after describing O. tortuosa, Leidy indicated the synonomy of O. tortuosa with O. microcephalus. This taxonomic view persisted for decades until Van Cleave, in 1924, recognized the validity of O. tortuosa, apparently without examining the type material of O. microcephalus. Subsequent workers have recognized two species of Oligacanthorhynchus from New World opossums: O. microcephalus from South American …

Varestrongylus Eleguneniensis Sp. N. (Nematoda: Protostrongylidae): A Widespread, Multi-Host Lungworm Of Wild North American Ungulates, With An Emended Diagnosis For The Genus And Explorations Of Biogeography, Guilherme G. Verocai, Susan J. Kutz, Manon Simard, Eric P. Hoberg

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Background: A putative new species of Varestrongylus has been recently recognized in wild North American ungulates based on the ITS-2 sequences of larvae isolated from feces during a wide geographic survey. No taxonomic description was provided, as adult specimens were not examined. Methods: Lungworm specimens were collected in the terminal bronchioles of muskoxen from Quebec, and a woodland caribou from central Alberta, Canada. The L3 stage was recovered from experimentally infected slugs (Deroceras spp.). Description of specimens was based on comparative morphology and integrated approaches. Molecular identity was determined by PCR and sequencing of the ITS-2 region of …

Air Sac Nematode Monopetalonema Alcedinis In A Belted Kingfisher (Megaceryle Alcyon) In Maryland, Usa, Ellen Bronson, Kathleen Kelly, Eric P. Hoberg

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Sporadic and geographically widespread reports of parasites affecting the Belted Kingfisher (Megaceryle alcyon) have been published but few have described details of the pathology. A female, adult kingfisher was found dead in a heavily wooded area of a zoo in Maryland, USA. At necropsy, numerous sexually dimorphic, 4.4–40.5-cm adult Monopetalonema alcedinis nematodes were found tightly wound within the coelomic cavity between organs and completely filling the caudal thoracic and abdominal air sacs. Abundant, 30–60-mm diameter, larvated, thick-walled ova were found in the bronchi and parabronchi, within the mesentery, and in the serosa of multiple coelomic organs. Monopetalonema alcedinis …

In Memoriam: Robert Lloyd Rausch—A Life In Nature And Field Biology, 1921–2012, Eric P. Hoberg

Harold W. Manter Laboratory of Parasitology: Faculty Publications

During his distinguished career, Robert Rausch, a man of great integrity and principles, served in his lifetime as a singular ambassador for parasitology in a broad international arena. Robert was a friend to many, was honored to be considered an equal among the nomadic bands of Nunamiut traversing the Brooks Range 60 years ago, and will be long remembered for the strength of his science and his perceptive views of the natural world.

Finding Them Before They Find Us: Informatics, Parasites, And Environments In Accelerating Climate Change, Daniel R. Brooks, Eric P. Hoberg, Walter A. Boeger, Scott Lyell Gardner, Kurt E. Galbreath, David Herczeg, Hugo H. Mejía-Madrid, S. Elizabeth Rácz, Altangerel Tsogtsaikhan Dursahinhan

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Parasites are agents of disease in humans, livestock, crops, and wildlife and are powerful representations of the ecological and historical context of the diseases they cause. Recognizing a nexus of professional opportunities and global public need, we gathered at the Cedar Point Biological Station of the University of Nebraska in September 2012 to formulate a cooperative and broad platform for providing essential information about the evolution, ecology, and epidemiology of parasites across host groups, parasite groups, geographical regions, and ecosystem types. A general protocol, documentation–assessment–monitoring–action (DAMA), suggests an integrated proposal to build a proactive capacity to understand, anticipate, and respond …

Transfer Of The U.S. National Parasite Collection [Announcement], Eric P. Hoberg, Anna J.. Phillips

Harold W. Manter Laboratory of Parasitology: Faculty Publications

In 2013, an agreement was articulated between the United States Department of Agriculture/Agricultural Research Service (ARS) and the Smithsonian Institution to transfer the National Parasite Collection (NPC) in its entirety (fluid specimens, slide specimens, frozen tissues, and reprints) to the National Museum of Natural History (NMNH) in Washington, D.C. Current collections staff, including senior curator Dr. Eric P. Hoberg and support scientists/managers from the ARS, will be transferred with the collection and, with adjunct appointments in the NMNH, will provide continuity and assistance for curation and accessibility during and after the relocation. New curatorial controls will be established under NMNH …

Transfer Of The United States National Parasite Collection [Announcement], Eric P. Hoberg, Anna J. Phillips

Harold W. Manter Laboratory of Parasitology: Faculty Publications

In 2013, an agreement was articulated between the United States Department of Agriculture/Agricultural Research Service (ARS) and the Smithsonian Institution to transfer the United States National Parasite Collection in its entirety (fluid specimens, slide specimens, frozen tissues and reprints) to the National Museum of Natural History (NMNH) in Washington, D.C. Current collections staff, including senior curator Dr. Eric P. Hoberg and support scientists/managers from the ARS will be transferred with the collection and with adjunct appointments in the NMNH will provide continuity and assistance for curation and accessibility during and after the relocation. New curatorial controls will be established under …

Anthropogenics: Human Influence On Global And Genetic Homogenization Of Parasite Populations, Dante S. Zarlenga, Eric P. Hoberg, Benjamin Rosenthal, Simonetti Mattiucci, Giuseppe Nascetti

Harold W. Manter Laboratory of Parasitology: Faculty Publications

The distribution, abundance, and diversity of life on Earth have been greatly shaped by human activities. This includes the geographic expansion of parasites; however, measuring the extent to which humans have influenced the dissemination and population structure of parasites has been challenging. In-depth comparisons among parasite populations extending to landscape-level processes affecting disease emergence have remained elusive. New research methods have enhanced our capacity to discern human impact, where the tools of population genetics and molecular epidemiology have begun to shed light on our historical and ongoing influence. Only since the 1990s have parasitologists coupled morphological diagnosis, long considered the …

Levisunguis Subaequalis N. G., N. Sp., A Tongue Worm (Pentastomida: Porocephalida: Sebekidae) Infecting Softshell Turtles, Apalone Spp. (Testudines: Trionychidae), In The Southeastern United States, Stephen S. Curran, Robin M. Overstreet, David E. Collins, George W. Benz

Harold W. Manter Laboratory of Parasitology: Faculty Publications

A new tongue worm (Pentastomida) belonging to the Sebekidae Sambon, 1922 (Porocephaloidea Sambon, 1922) is described based on exemplars collected from softshell terrapins Apalone spinifera aspera (Agassiz) and Apalone ferox (Schneider) in the southeastern United States; a new genus is erected to accommodate the new species. The new species belongs in the Sebekidae because adults possess four simple hooks arranged in a trapezoid pattern on the ventral surface of the cephalothorax, a mouth opening between the anterior and posterior pairs of hooks, a terminal anus, an elongated uterus with preanal uterine pore, and a Y-shaped seminal vesicle. Nymphs possess geminate …

Large And Medium-Sized Mammals Of Carajás National Forest, Pará State, Brazil, Andréa Siqueira Carvalho, Frederico Drumond Martins, Francilma Mendes Dutra, Donald Gettinger, Fernanda Martins-Hatano, Helena De Godoy Bergallo

Harold W. Manter Laboratory of Parasitology: Faculty Publications

The Carajás National Forest is located in the Amazonian region, Pará State, Brazil and is part of a mosaic of conservation units comprising over one million hectares. This region has been explored for its mineral reserves, but knowledge of the distribution of animals and plants is lacking. The objective of this paper is to provide a list of the medium and large-sized mammals recorded from the Carajás NF. We used four methods to record mammals: linear transects, camera traps, records of road-killed animals, and opportunistic observations. We recorded 45 species distributed in nine taxonomic orders, eight of them currently on …

Structure And Function Of Human Dnaj Homologue Subfamily A Member 1 (Dnaja1) And Its Relationship To Pancreatic Cancer, Jaime L. Stark, Kamiya Mehla, Nina V. Chaika, Thomas B. Acton, Rong Xiao, Pankaj K. Singh, Gaetano T. Montelione, Robert Powers

Robert Powers Publications

Pancreatic cancer has a dismal 5 year survival rate of 5.5% that has not been improved over the past 25 years despite an enormous amount of effort. Thus, there is an urgent need to identify truly novel yet druggable protein targets for drug discovery. The human protein DnaJ homologue subfamily A member 1 (DNAJA1) was previously shown to be downregulated 5- fold in pancreatic cancer cells and has been targeted as a biomarker for pancreatic cancer, but little is known about the specific biological function for DNAJA1 or the other members of the DnaJ family encoded in the human genome. …

Identification Of Low Molecular Weight Compounds Inhibiting Growth Of Corynebacteria: Potential Lead Compounds For Antibiotics, Jaime L. Stark, Jennifer C. Copeland, Alexander Eletsky, Greg A. Somerville, Thomas Szyperski, Robert Powers

Robert Powers Publications

The genus Corynebacterium consists of nearly seventy species and is closely related to the genera Mycobacterium, Nocardia, and Rhodococcus. The characteristic traits of Corynebacteria include cells that are shaped like straight rods with clubbed ends, as well as an extra cell wall layer consisting of mycolic acids covalently bound to the peptidoglycan layer which adds an additional layer of protection against antibiotics. Corynebacteria are very well studied and outstandingly important for the large scale biotechnological production of amino acids and nucleotides. Moreover, Corynebacteria produce several pathogens that affect humans and livestock. Toxins produced by C. diphtheriae and C. …

Sjl Mice Infected With Acanthamoeba Castellanii Develop Central Nervous System Autoimmunity Through The Generation Of Cross-Reactive T Cells For Myelin Antigens, Jay Reddy, Chandirasegaran Massilamany, Francine Marciano-Cabral, Bruno Da Rocha-Azevedo, Melissa Jamerson, Arunakumar Gangaplara, David Steffen, Rana Zabad, Zsolt Illes, Raymond Sobel

School of Veterinary and Biomedical Sciences: Faculty Publications

We recently reported that Acanthamoeba castellanii (ACA), an opportunistic pathogen of the central nervous system (CNS) possesses mimicry epitopes for proteolipid protein (PLP) 139–151 and myelin basic protein 89–101, and that the epitopes induce experimental autoimmune encephalomyelitis (EAE) in SJL mice reminiscent of the diseases induced with their corresponding cognate peptides. We now demonstrate that mice infected with ACA also show the generation of crossreactive T cells, predominantly for PLP 139–151, as evaluated by T cell proliferation and IAs/dextramer staining. We verified that PLP 139–151-sensitized lymphocytes generated in infected mice contained a high proportion of T helper 1 cytokineproducing cells, …

Update On Colistin In Clinical Practice, Wafa A. Alfahad, Ali S. Omrani

Saudi Medical Journal

Considerable progress has been made in the last decade towards better understanding of the optimal clinical use of colistin. It has become evident that higher intravenous (iv) colistin methanesulfonate (CMS) doses are important, probably with the addition of a loading dose in critically ill patients. Higher CMS doses lead to increased risk of nephrotoxicity, which seems reversible in most cases. Intravenous colistin is reasonably efficacious, but should continue to be considered only in the absence of safer alternatives. Although theoretically appealing, there is insufficient evidence to support inhaled colistin mono-therapy in non-cystic fibrosis patients. Moreover, the balance of evidence available …

Salmonella Bacilli Negative Image Recognized On Diff-Quik Stain From Pleural Fluid Cytology, Zahrah H. Al-Faraj, Hoda A. Hassan, Baha A. Abdalhamid, Mousa A. Al-Abbadi

Saudi Medical Journal

Understanding the significance of cytopathological tests in evaluating various infectious processes have become very essential nowadays, as it is a safe, fast, and cost-effective procedure. We present a case of a 52-year-old male with Salmonella empyema where the causative organisms were initially identified on cytology, and subsequently confirmed by microbiological culture. Diff-Quik stained smears showed many colorless, slender, fat short bacilli, which were visualized against the blue-gray background of the smear. These bacilli were identified both intracellularly inside the histiocytes and neutrophils cytoplasm as well as extracellularly in the smear background. We consider that this negative image represents the organism …

Low Prevalence Of Methicillin Resistant As Determined By An Automated Identification System In Two Private Hospitals In Nairobi, Kenya: A Cross Sectional Study, Geoffrey Omuse, Beatrice Kabera, Gunturu Revathi

Pathology, East Africa

Background: Staphylococcus aureus (S.aureus) is a major cause of both healthcare and community acquired infections. In developing countries, manual phenotypic tests are the mainstay for the identification of staphylococci with the tube and slide coagulase tests being relied upon as confirmatory tests for S. aureus. The subjectivity associated with interpretation of these tests may result in misidentification of coagulase negative staphylococci as S.aureus. Given that antibiotic resistance is more prevalent in CONS, this may result in over estimation of methicillin resistant S.aureus (MRSA) prevalence.

Methods: A review of susceptibility data from all non-duplicate S.aureus isolates generated between March 2011 and …

Using Quantitative Disease Dynamics As A Tool For Guiding Response To Avian Influenza In Poultry In The United States Of America, K. M. Pepin, E. Spackman, J. D. Brown, K. L. Pabilonia, Lindsey P. Garber, J. Todd Weaver, D. A. Kennedy, Kelly A. Patyk, K. P. Huyvaert, Ryan S. Miller, Alan B. Franklin, Kerri Pedersen, T. L. Bogich, P. Rohani, Susan A. Shriner, Colleen T. Webb, S. Riley

United States Department of Agriculture Wildlife Services: Staff Publications

Wild birds are the primary source of genetic diversity for influenza A viruses that eventually emerge in poultry and humans. Much progress has been made in the descriptive ecology of avian influenza viruses (AIVs), but contributions are less evident from quantitative studies (e.g., those including disease dynamic models). Transmission between host species, individuals and flocks has not been measured with sufficient accuracy to allow robust quantitative evaluation of alternate control protocols. We focused on the United States of America (USA) as a case study for determining the state of our quantitative knowledge of potential AIV emergence processes from wild hosts …

A Conceptual Model For The Impact Of Climate Change On Fox Rabies In Alaska, 1980–2010, B. I. Kim, J. D. Blanton, A. T. Gilbert, L. Castrodale, K. Hueffer, D. Slate, C. E. Rupprecht

United States Department of Agriculture Wildlife Services: Staff Publications

The direct and interactive effects of climate change on host species and infectious disease dynamics are likely to initially manifest at latitudinal extremes. As such, Alaska represents a region in the United States for introspection on climate change and disease. Rabies is enzootic among arctic foxes (Vulpes lagopus) throughout the northern polar region. In Alaska, arctic and red foxes (Vulpes vulpes) are reservoirs for rabies, with most domestic animal and wildlife cases reported from northern and western coastal Alaska. Based on passive surveillance, a pronounced seasonal trend in rabid foxes occurs in Alaska, with a peak in winter and spring. …

Bat Rabies In Guatemala, James E. Ellison, Amy T. Gilbert, Sergio Recuenco, David Moran, Danilo A. Alvarez, Natalia Kuzmina, Daniel L. Garcia, Leonard F. Peruski, Mary T. Mendonca, Kim A. Lindblade, Charles E. Rupprecht

United States Department of Agriculture Wildlife Services: Staff Publications

Rabies in bats is considered enzootic throughout the New World, but few comparative data are available for most countries in the region. As part of a larger pathogen detection program, enhanced bat rabies surveillance was conducted in Guatemala, between 2009 and 2011. A total of 672 bats of 31 species were sampled and tested for rabies. The prevalence of rabies virus (RABV) detection among all collected bats was low (0.3%). Viral antigens were detected and infectious virus was isolated from the brains of two common vampire bats (Desmodus rotundus). RABV was also isolated from oral swabs, lungs and …

Shedding Of A Low Pathogenic Avian Influenza Virus In A Common Synanthropic Mammal – The Cottontail Rabbit, J. Jeffrey Root, Susan A. Shriner, Kevin T. Bentler, Thomas Gidlewski, Nicole L. Mooers, Terry R. Spraker, Kaci K. Vandalen, Heather J. Sullivan, Alan B. Franklin

United States Department of Agriculture Wildlife Services: Staff Publications

Background: Cottontails (Sylvilagus spp.) are common mammals throughout much of the U.S. and are often found in peridomestic settings, potentially interacting with livestock and poultry operations. If these animals are susceptible to avian influenza virus (AIV) infections and shed the virus in sufficient quantities they may pose a risk for movement of avian influenza viruses between wildlife and domestic animals in certain situations.

Methodology/Principal Findings: To assess the viral shedding potential of AIV in cottontails, we nasally inoculated fourteen cottontails with a low pathogenic AIV (H4N6). All inoculated cottontails shed relatively large quantities of viral RNA both nasally ( …

Ecological Routes Of Avian Influenza Virus Transmission To A Common Mesopredator: An Experimental Evaluation Of Alternatives, J. Jeffrey Root, Kevin T. Bentler, Susan A. Shriner, Nicole L. Mooers, Kaci K. Vandalen, Heather J. Sullivan, Alan B. Franklin

United States Department of Agriculture Wildlife Services: Staff Publications

Background: Wild raccoons have been shown to be naturally exposed to avian influenza viruses (AIV). However, the mechanisms associated with these natural exposures are not well-understood.

Methodology/Principal Findings: We experimentally tested three alternative routes (water, eggs, and scavenged waterfowl carcasses) of AIV transmission that may explain how raccoons in the wild are exposed to AIV. Raccoons were exposed to 1) water and 2) eggs spiked with an AIV (H4N6), as well as 3) mallard carcasses experimentally inoculated with the same virus. Three of four raccoons exposed to the high dose water treatment yielded apparent nasal shedding of >10^2.0 PCR …

Spatial Epidemiology Of Escherichia Coli O157:H7 In Dairy Cattle In Relation To Night Roosts Of Sturnus Vulgaris (European Starling) In Ohio, Usa (2007–2009), A. L. Swirski, D. L. Pearl, M. L. Williams, H. J. Homan, G. M. Linz, N. Cernicchiaro, J. T. Lejeune

United States Department of Agriculture Wildlife Services: Staff Publications

The goal of our study was to use spatial scan statics to determine whether the night roosts of European starlings (Sturnus vulgaris) act as point sources for the dissemination of Escherichia coli O157:H7 among dairy farms. From 2007 to 2009, we collected bovine faecal samples (n = 9000) and starling gastrointestinal contents (n = 430) from 150 dairy farms in northeastern Ohio, USA. Isolates of E. coli O157:H7 recovered from these samples were subtyped using multilocus variable-number tandem repeat analysis (MLVA). Generated MLVA types were used to construct a dendrogram based on a categorical multistate coefficient and unweighted …

Genetic Analysis Of A Bison Bison Herd Derived From The Yellowstone National Park Population, Julia A. Herman, Antoinette J. Piaggio, Natalie D. Halbert, Jack C. Rhyan, M. D. Salman

United States Department of Agriculture Wildlife Services: Staff Publications

The objective of this study is to inventory the current genetic diversity of the bison quarantine feasibility study (BQFS) herd originating from Yellowstone National Park (YNP) using previously described microsatellite, mitochondrial and nuclear DNA markers with the aim to determine the degree, if any, of cattle DNA introgression in this herd. This work can provide an important tool in monitoring and managing bison genetic diversity as brucellosis-free reintroduced herds are re-established throughout the US for conservation purposes. The BQFS composed of 89 Bison bison from YNP that were quarantined and tested to qualify as free of brucellosis in 2006 – …

Environmental Salmonella In Agricultural Fair Poultry Exhibits In Colorado, K. L. Pabilonia, K. J. Cadmus, T. M. Lingus, D. S. Bolte, M. M. Russell, D. C. Van Metre, M. M. Erdman

United States Department of Agriculture Wildlife Services: Staff Publications

Salmonella enterica is a common zoonotic pathogen in humans. Transmission typically occurs through consumption of contaminated food products or contact with infected animals, including poultry or their environment. The objective of this study was to estimate the frequency of Salmonella contamination in the environment in poultry exhibits at agricultural fairs. Samples were collected from cages, feed, floors and tables in the exhibit and cultured for Salmonella. At least one environmental sample was positive for Salmonella in 10 of 11 fairs (91%), and Salmonella was isolated from 28 of 55 environmental samples (50.9%). Eleven different serotypes were detected. Results of …

Predicted Wildlife Disease-Related Climate Change Impacts Of Specific Concern To Usda Aphis Wildlife Services, Timothy P. Algeo, Richard B. Chipman, Dennis Slate, Jerome E. Freier, Thomas J. Deliberto

United States Department of Agriculture Wildlife Services: Staff Publications

USDA APHISWildlife Services plans for and responds to a variety of exigencies such as wildlife hazards to aircraft, disease emergence from wildlife translocations, oral rabies vaccine barrier compromises, and extreme weather events. These are often collaborative efforts with state and federal agencies and others. Climate change based in part on fossil fuel use and methane gas emissions has predictable as well as unknown consequences. As a federal leader in wildlife disease research and management, it is incumbent upon Wildlife Services to be current with the scientific literature; assess potential impacts and wildlife disease management intervention needs from predicted climate change …

Wildlife Damage Management: Changes Over The Last 40 Years And A Look At The Future, Kathleen A. Fagerstone

United States Department of Agriculture Wildlife Services: Staff Publications

Since becoming a wildlife biologist 40 years ago, I have seen many changes. Yet some things have remained the same, like the economic impact of wildlife damage, which was high in 1974 and even higher now. In 2014, the worldwide cost of damage by vertebrate pests to agriculture will exceed $1 billion. The world’s human population has increased at an unprecedented rate, while some wildlife populations have also burgeoned over the past 40 years due to land-use changes and effective management programs. These simultaneous human and wildlife population increases have led to increasing conflicts between humans and wildlife. Nor has …

A Recent Epizootic Of Skunk Rabies And Associated Spillover In Northern Colorado, Usa, Amy Gilbert, Dennis Kohler, Tara Rigg, Justin W. Fischer, Terry Spraker, Karen Fox, Kurt C. Vercauteren

United States Department of Agriculture Wildlife Services: Staff Publications

Rabies is a fatal viral zoonosis that is transmitted by bite contact with saliva of an infected animal. In the U.S., human deaths are rare, but each year over 5,000 rabid animals are reported and over 90% of cases are from wildlife. Multiple species of carnivores and bats are the primary sylvatic reservoirs in the U.S., and several variants circulate independently among these two taxonomic orders. Rabies prevention efforts led by USDA APHIS Wildlife Services using live recombinant vaccine baiting began in 1995 and currently target raccoons and canids, but the territory of the south-central skunk rabies virus variant has …

Fitting Outbreak Models To Data From Many Small Norovirus Outbreaks, Eamon B. O'Dea, Kim M. Pepin, Ben A. Lopman, Claus O. Wilke

United States Department of Agriculture Wildlife Services: Staff Publications

Infectious disease often occurs in small, independent outbreaks in populations with varying characteristics. Each outbreak by itself may provide too little information for accurate estimation of epidemic model parameters. Here we show that using standard stochastic epidemic models for each outbreak and allowing parameters to vary between outbreaks according to a linear predictor leads to a generalized linear model that accurately estimates parameters from many small and diverse outbreaks. By estimating initial growth rates in addition to transmission rates, we are able to characterize variation in numbers of initially susceptible individuals or contact patterns between outbreaks. With simulation, we find …

An Agent-Based Movement Model To Assess The Impact Of Landscape Fragmentation On Disease Transmission, Jeff A. Tracey, Sarah N. Bevins, Sue Vandewoude, Kevin R. Crooks

United States Department of Agriculture Wildlife Services: Staff Publications

Landscape changes can result in habitat fragmentation and reduced landscape connectivity, limiting the ability of animals to move across space and altering infectious disease dynamics in wildlife. In this study, we develop and implement an agent-based model to assess the impacts of animal movement behavior and landscape structure on disease dynamics. We model a susceptible/infective disease state system applicable to the transmission of feline immunodeficiency virus in bobcats in the urbanized landscape of coastal southern California. Our agent-based model incorporates animal movement behavior, pathogen prevalence, transmission probability, and habitat fragmentation to evaluate how these variables influence disease spread in urbanizing …