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2014

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A Rare Sequence Variant In Intron 1 Of Thap1 Is Associated With Primary Dystonia, Joel S. Perlmutter, Brad A. Racette, Randal C. Paniello, Et Al Jan 2014

A Rare Sequence Variant In Intron 1 Of Thap1 Is Associated With Primary Dystonia, Joel S. Perlmutter, Brad A. Racette, Randal C. Paniello, Et Al

Open Access Publications

No abstract provided.


Joint Testing Of Genotypic And Gene-Environment Interaction Identified Novel Association For Bmp4 With Non-Syndromic Cl/P In An Asian Population Using Data From An International Cleft Consortium, Qianqian Chen, Hong Wang, Holger Schwender, Tianxiao Zhang, Jacqueline B. Hetmanski, Yah-Huei Wu Chou, Xiaoqian Ye, Vincent Yeow, Samuel S. Chong, Bo Zhang, Ethylin Wang Jabs, Margaret M. Parker, Alan F. Scott, Terri H. Beaty Jan 2014

Joint Testing Of Genotypic And Gene-Environment Interaction Identified Novel Association For Bmp4 With Non-Syndromic Cl/P In An Asian Population Using Data From An International Cleft Consortium, Qianqian Chen, Hong Wang, Holger Schwender, Tianxiao Zhang, Jacqueline B. Hetmanski, Yah-Huei Wu Chou, Xiaoqian Ye, Vincent Yeow, Samuel S. Chong, Bo Zhang, Ethylin Wang Jabs, Margaret M. Parker, Alan F. Scott, Terri H. Beaty

Open Access Publications

No abstract provided.


Optimal Body Weight For Health And Longevity: Bridging Basic, Clinical, And Population Research, Luigi Fontana, Frank B. Hu Jan 2014

Optimal Body Weight For Health And Longevity: Bridging Basic, Clinical, And Population Research, Luigi Fontana, Frank B. Hu

Open Access Publications

No abstract provided.


Multicenter Evaluation Of Computer Automated Versus Traditional Surveillance Of Hospital-Acquired Bloodstream Infections, Michael Y. Lin, Keith F. Woeltje, Yosef M. Khan, Bala Hota, Joshua A. Doherty, Tara B. Borlawsky, Kurt Stevenson, Scott K. Fridkin, Robert A. Weinstein, William E. Trick Jan 2014

Multicenter Evaluation Of Computer Automated Versus Traditional Surveillance Of Hospital-Acquired Bloodstream Infections, Michael Y. Lin, Keith F. Woeltje, Yosef M. Khan, Bala Hota, Joshua A. Doherty, Tara B. Borlawsky, Kurt Stevenson, Scott K. Fridkin, Robert A. Weinstein, William E. Trick

Open Access Publications

No abstract provided.


Dendritic Cells In Dengue Virus Infection: Targets Of Virus Replication And Mediators Of Immunity, Michael A. Schmid, Michael S. Diamond, Eva Harris Jan 2014

Dendritic Cells In Dengue Virus Infection: Targets Of Virus Replication And Mediators Of Immunity, Michael A. Schmid, Michael S. Diamond, Eva Harris

Open Access Publications

No abstract provided.


State Practitioner Insights Into Local Public Health Challenges And Opportunities In Obesity Prevention: A Qualitative Study, Katherine A. Stamatakis, Moira Lewis, Elaine C. Khoong, Claire Lasee Jan 2014

State Practitioner Insights Into Local Public Health Challenges And Opportunities In Obesity Prevention: A Qualitative Study, Katherine A. Stamatakis, Moira Lewis, Elaine C. Khoong, Claire Lasee

Open Access Publications

No abstract provided.


Antisense Reduction Of The Protein Tau Attenuates Neuronal Hyper-Excitability And Permits Clearance Of Intraneuronal Tau Accumulations In Vivo, Sarah Devos Jan 2014

Antisense Reduction Of The Protein Tau Attenuates Neuronal Hyper-Excitability And Permits Clearance Of Intraneuronal Tau Accumulations In Vivo, Sarah Devos

Open Access Publications

No abstract provided.


Clinical Trial Design In The Era Of Comparative Effectiveness Research, Anke C. Winter, Graham A. Colditz Jan 2014

Clinical Trial Design In The Era Of Comparative Effectiveness Research, Anke C. Winter, Graham A. Colditz

Open Access Publications

No abstract provided.


Chronic Lung Allograft Dysfunction Following Lung Transplantation: Challenges And Solutions, Bradford C. Bemiss, Chad A. Witt Jan 2014

Chronic Lung Allograft Dysfunction Following Lung Transplantation: Challenges And Solutions, Bradford C. Bemiss, Chad A. Witt

Open Access Publications

No abstract provided.


Phylogenomics And The Dynamic Genome Evolution Of The Genus Streptococcus, Vincent P. Richards, Sara R. Palmer, Paulina D. Pavinski Bitar, Xiang Qin, George M. Weinstock, Sarah K. Highlander, Christopher D. Town, Robert A. Burne, Michael J. Stanhope Jan 2014

Phylogenomics And The Dynamic Genome Evolution Of The Genus Streptococcus, Vincent P. Richards, Sara R. Palmer, Paulina D. Pavinski Bitar, Xiang Qin, George M. Weinstock, Sarah K. Highlander, Christopher D. Town, Robert A. Burne, Michael J. Stanhope

Open Access Publications

No abstract provided.


Bkca Channel Inhibitor Modulates The Tumorigenic Ability Of Hormone-Independent Breast Cancer Cells Via The Wnt Pathway, Brandon M. Schickling, Sarah K. England, Nukhet Aykin-Burns, Lyse A. Norian, Kimberly K. Leslie, Victoria P. Frieden-Korovkina Jan 2014

Bkca Channel Inhibitor Modulates The Tumorigenic Ability Of Hormone-Independent Breast Cancer Cells Via The Wnt Pathway, Brandon M. Schickling, Sarah K. England, Nukhet Aykin-Burns, Lyse A. Norian, Kimberly K. Leslie, Victoria P. Frieden-Korovkina

Open Access Publications

No abstract provided.


Cognitive Function In Ambulatory Patients With Systolic Heart Failure: Insights From The Warfarin Versus Aspirin In Reduced Cardiac Ejection Fraction (Warcef) Trial, Douglas L. Mann, Et Al Jan 2014

Cognitive Function In Ambulatory Patients With Systolic Heart Failure: Insights From The Warfarin Versus Aspirin In Reduced Cardiac Ejection Fraction (Warcef) Trial, Douglas L. Mann, Et Al

Open Access Publications

No abstract provided.


Psychiatric Correlates Of Snuff And Chewing Tobacco Use, Qiang Fu, Michael G. Vaughn, Li-Tzy Wu, Andrew C. Heath Jan 2014

Psychiatric Correlates Of Snuff And Chewing Tobacco Use, Qiang Fu, Michael G. Vaughn, Li-Tzy Wu, Andrew C. Heath

Open Access Publications

No abstract provided.


Participants’ Perceptions Of A Group Based Program Incorporating Hands-On Meal Preparation And Pedometer-Based Self-Monitoring In Type 2 Diabetes, Kaberi Dasgupta, Soghra Jarvandi, Mirella De Civita, Sabrina Pillay, Samantha Hajna, Rejeanne Gougeon, Abeer Bader, Deborah Da Costa Jan 2014

Participants’ Perceptions Of A Group Based Program Incorporating Hands-On Meal Preparation And Pedometer-Based Self-Monitoring In Type 2 Diabetes, Kaberi Dasgupta, Soghra Jarvandi, Mirella De Civita, Sabrina Pillay, Samantha Hajna, Rejeanne Gougeon, Abeer Bader, Deborah Da Costa

Open Access Publications

No abstract provided.


Genetic Analysis Of Circadian Responses To Low Frequency Electromagnetic Fields In Drosophila Melanogaster, Giorgio Fedele, Mathew D. Edwards, Supriya Bhutani, John M. Hares, Manuel Murbach, Edward W. Green, Stephane Dissel, Michael H. Hasting, Ezio Rosato, Charalambos P. Kyriacou Jan 2014

Genetic Analysis Of Circadian Responses To Low Frequency Electromagnetic Fields In Drosophila Melanogaster, Giorgio Fedele, Mathew D. Edwards, Supriya Bhutani, John M. Hares, Manuel Murbach, Edward W. Green, Stephane Dissel, Michael H. Hasting, Ezio Rosato, Charalambos P. Kyriacou

Open Access Publications

No abstract provided.


Structure Of Cellular Escrt-Iii Spirals And Their Relationship To Hiv Budding, Anil G. Cashikar, Soomin Shim, Robyn Roth, Michael R. Maldazys, John E. Heuser, Phyllis I. Hanson Jan 2014

Structure Of Cellular Escrt-Iii Spirals And Their Relationship To Hiv Budding, Anil G. Cashikar, Soomin Shim, Robyn Roth, Michael R. Maldazys, John E. Heuser, Phyllis I. Hanson

Open Access Publications

No abstract provided.


Invariance And Plasticity In The Drosophila Melanogaster Metabolomic Network In Response To Temperature, Ramkumar Hariharan, Jessica M. Hoffman, Ariel S. Thomas, Quinlyn A. Soltow, Dean P. Jones, Daniel E.L. Promislow Jan 2014

Invariance And Plasticity In The Drosophila Melanogaster Metabolomic Network In Response To Temperature, Ramkumar Hariharan, Jessica M. Hoffman, Ariel S. Thomas, Quinlyn A. Soltow, Dean P. Jones, Daniel E.L. Promislow

Open Access Publications

No abstract provided.


Missed Opportunities: Racial And Neighborhood Socioeconomic Disparities In Emergency Colorectal Cancer Diagnosis And Surgery, Sandi L. Pruitt, Nicholas O. Davidson, Samir Gupta, Yan Yan, Mario Schootman Jan 2014

Missed Opportunities: Racial And Neighborhood Socioeconomic Disparities In Emergency Colorectal Cancer Diagnosis And Surgery, Sandi L. Pruitt, Nicholas O. Davidson, Samir Gupta, Yan Yan, Mario Schootman

Open Access Publications

No abstract provided.


Short Communication: The Veterans Aging Cohort Study Index Is An Effective Tool To Assess Baseline Frailty Status In A Contemporary Cohort Of Hiv-Infected Persons, Gerome V. Escota, Pragna Patel, John T. Brooks, Tim Bush, Lois Conley, Jason Baker, Erna M. Kojic, John Hammer, Nur F. Önen Jan 2014

Short Communication: The Veterans Aging Cohort Study Index Is An Effective Tool To Assess Baseline Frailty Status In A Contemporary Cohort Of Hiv-Infected Persons, Gerome V. Escota, Pragna Patel, John T. Brooks, Tim Bush, Lois Conley, Jason Baker, Erna M. Kojic, John Hammer, Nur F. Önen

Open Access Publications

No abstract provided.


Dynamometer-Based Measure Of Spasticity Confirms Limited Association Between Plantarflexor Spasticity And Walking Function In Persons With Multiple Sclerosis, Theodore R. Kremer, Linda R. Van Dillen, Joanne M. Wagner Jan 2014

Dynamometer-Based Measure Of Spasticity Confirms Limited Association Between Plantarflexor Spasticity And Walking Function In Persons With Multiple Sclerosis, Theodore R. Kremer, Linda R. Van Dillen, Joanne M. Wagner

Open Access Publications

No abstract provided.


Nanotechnology And Its Implication In Medical Science, Syed Ahsan Ali, M. Tariq Jan 2014

Nanotechnology And Its Implication In Medical Science, Syed Ahsan Ali, M. Tariq

Department of Medicine

No abstract provided.


Mediastinal Synovial Sarcoma., Niaz Hussain Soomro, Sanaullah Junejo, Aneeqa Ahsan Zafar, Shirin Siddiqi, Ghulam H Jan 2014

Mediastinal Synovial Sarcoma., Niaz Hussain Soomro, Sanaullah Junejo, Aneeqa Ahsan Zafar, Shirin Siddiqi, Ghulam H

Department of Medicine

The mediastinum is an uncommon site of synovial sarcoma which is a rare soft tissue malignancy. An 18 year old boy was admitted for right sided chest pain since one year. Based on the CT scan chest findings, tru-cut biopsy of the mass was performed and histopathology initially reported as neurofibroma. The tumor was excised via posterolateral thoracotomy and excisional biopsy established the diagnosis of primary synovial sarcoma arising from the mediastinum. Patient was started on adjuvant chemotherapy at the oncologist tumor board’s recommendation and he received 6 cycles of adriamycin and ifosfamide. At last follow up he is free …


Task-Based Learning Versus Problem-Oriented Lecture In Neurology Continuing Medical Education., Farhan Vakani, Wasim Jafri, Amina Ahmad, Aziz Sonawalla, Mughis Sheerani Jan 2014

Task-Based Learning Versus Problem-Oriented Lecture In Neurology Continuing Medical Education., Farhan Vakani, Wasim Jafri, Amina Ahmad, Aziz Sonawalla, Mughis Sheerani

Department of Medicine

Objective: To determine whether general practitioners learned better with task-based learning or problem-oriented lecture in a Continuing Medical Education (CME) set-up.

Study Design: Quasi-experimental study.

Place and Duration of Study: The Aga Khan University, Karachi campus, from April to June 2012.

Methodology: Fifty-nine physicians were given a choice to opt for either Task-based Learning (TBL) or Problem Oriented Lecture (PBL) in a continuing medical education set-up about headaches. The TBL group had 30 participants divided into 10 small groups, and were assigned case-based tasks. The lecture group had 29 participants. Both groups were given a pre and a post-test. Pre/post …


Dusty Order: Law Enforcement And Participant Cooperation At Burning Man, Manuel A. Gomez Jan 2014

Dusty Order: Law Enforcement And Participant Cooperation At Burning Man, Manuel A. Gomez

Faculty Books

Media depictions of Burning Man focus on the picturesque and eccentric appearance of the weeklong affair. The event is sometimes misportrayed as a lawless environment where participants are encouraged to engage in rowdy behavior. Most carnivalesque events offer an escape from reality and are generally thought to enable unruly conduct. Despite stereotypes, Burning Man is a different beast. Not only is the crime rate in Black Rock City lower than any other city of comparable size, but Burners show a high level of cooperative and law abiding behavior that helps maintain the social order without depending on official means of …


African American And Hispanic Stem Students' Engagement At Predominantly White Institutions, Terrell Lamont Strayhorn, Fei Bie, Leroy L. Long Iii, Blossom A. Barrett Jan 2014

African American And Hispanic Stem Students' Engagement At Predominantly White Institutions, Terrell Lamont Strayhorn, Fei Bie, Leroy L. Long Iii, Blossom A. Barrett

Publications

Although research has shown that involvement is a helpful predictor of students’ future success, underrepresented minorities (i.e., African Americans and Hispanics) face unique obstacles at predominantly White institutions, which limit their engagement in educationally purposeful activities. Survey data from a 2007 administration of the National Survey of Student Engagement (NSSE) were analyzed to measure African American and Hispanic students’ engagement in educationally purposeful activities. Results from the present study found that student satisfaction in college is positively related to time spent preparing for class and frequency of interactions with faculty members about careers. Furthermore, African American and Hispanic science, technology, …


The Effectiveness Of The Concordance-Discordance Model: Identifying Learning Disabilities In School-Aged Children, Bryan Hendricks Jan 2014

The Effectiveness Of The Concordance-Discordance Model: Identifying Learning Disabilities In School-Aged Children, Bryan Hendricks

PCOM Psychology Dissertations

After the reauthorization of Individuals with Disabilities Education Act (IDEA) in
2004, the federal regulations indicated that there are three possible methods for the identification of a Specific Learning Disability (SLD). The three methods include the ability-achievement discrepancy (AAD), Response to Intervention (RTI), and the addition of a third method, which consists of other alternative research-based procedures. Hale and Fiorello (2004) proposed the use of a Concordance-Discordance Model (CDM), which suggests that learning disabled students have discordance between processing strength and both processing weakness and achievement deficit. In addition, SLD students have a concordance between the achievement deficit and processing …


Service Engagement And Serious Mental Illness: The Obstacles And Barriers To Attendance In A Post-Treatment Recovery Outpatient Setting, Marisa Jeanne Friedman Jan 2014

Service Engagement And Serious Mental Illness: The Obstacles And Barriers To Attendance In A Post-Treatment Recovery Outpatient Setting, Marisa Jeanne Friedman

PCOM Psychology Dissertations

This qualitative study examined the factors that affect treatment adherence and service engagement in individuals with serious mental illnesses (SMI). A semistructured interview was used to collect data from treatment adherent and treatment nonadherent adults with SMI. What factors make one more or less likely to disengage from treatment? What boundaries stand in the way of quality mental-health care, and how do adults with SMI overcome these barriers? Service engagement in the population with SMI in the study was explained according to three healthcare behavioral models, the health belief model, the network episode model, and the demoralization framework model. Data …


Lqts: Gender Differences And Mother-Son Vs. Mother-Daughter, Thea Gallagher Jan 2014

Lqts: Gender Differences And Mother-Son Vs. Mother-Daughter, Thea Gallagher

PCOM Psychology Dissertations

Long QT syndrome is a chronic disorder, and one of the most common genetic arrhythmia syndromes that can cause unexpected cardiac arrest and death in individuals. Treatment options include medications, use of implantable cardioverter defibrillators (ICD) and restricting activities of daily life. Minimal research exists exploring the specific psychosocial aspects of the illness and/or the impact on the quality of life of individuals and families coping with the management and diagnosis of this illness. Furthermore, little research has attempted to understand the role of gender differences and mother-child perceptions among individuals with Long QT syndrome. The current study used data …


Improving Cognitive-Behavioral Therapy Homework Adherence With Change Talk And Commitment Language: A Cognitive Dissonance Perspective Of Behavioral Change, Robert J. Brecher Jan 2014

Improving Cognitive-Behavioral Therapy Homework Adherence With Change Talk And Commitment Language: A Cognitive Dissonance Perspective Of Behavioral Change, Robert J. Brecher

PCOM Psychology Dissertations

Adherence to homework assigned during cognitive-behavioral therapy (CBT) is an important factor contributing to positive outcomes. However, rates of adherence are poor, limited evidence supporting methods to improve adherence is limited. The current study aimed to develop and test an intervention designed to promote CBT homework adherence based on cognitive dissonance theory. Patients participating in outpatient CBT were randomly assigned to either an experimental or a control condition. In the experimental condition, participants engaged in an induced-compliance procedure eliciting change talk targeting the recommended homework activity. The control condition consisted of treatment as usual. Owing to limited sample size (n …


In Their Own Words: Perceived Experiences And Family Functioning Of Suicide Survivors Before And After Suicide Loss, Wendy Shallcross Lam Jan 2014

In Their Own Words: Perceived Experiences And Family Functioning Of Suicide Survivors Before And After Suicide Loss, Wendy Shallcross Lam

PCOM Psychology Dissertations

This research explored the unique experiences of relatives of individuals who have died by suicide, termed suicide survivors, in an in-depth fashion using qualitative methods. Through a semi-structured interview, the present study explored how families dealt with general stress prior to the experience of suicide loss, how they handled the loss of a family member to suicide, and what has been used to cope in the aftermath. A major focus was to explore whether or not the event of suicide dramatically altered family dynamics or if families continued a pre-existing interaction pattern established prior to the loss. The results revealed …