Digital Commons Network^™

Sex Differences In Ss-Adrenergic Responsiveness Of Isolated Rabbit Hearts, Gregory Hoeker

All ETDs from UAB

Stimulation of adrenergic receptors by catecholamines is the predominant regulatory mechanism for cardiovascular performance. Many cardiovascular diseases involve changes in ß-adrenergic signaling that often lead to decreased cardiac performance, cardiac arrhythmias, and/or sudden cardiac death. This has made ß-adrenergic receptors (ß-ARs) a significant therapeutic target in cardiovascular disease. Sex differences in ß-adrenergic responsiveness have been associated with cardioprotection in females, conferring a survival benefit in female patients with heart failure (HF). The heart contains three distinct ß-ARs: ß1-, ß2-, and ß3-AR. It is not known how each ß-AR subtype contributes to the sex differences in ß-responsiveness, let alone how this …

Effect Of Protons On The Biology Of Human Gliomas, Avinash Vinayak Honasoge

All ETDs from UAB

Gliomas are the most common and most deadly primary brain cancer. Patient outcome for the most malignant variety, the World Health Organization (WHO) Type IV glioblastoma multiforme (GBM), has stagnated over the last several decades - the best combination treatment of surgical resection, radiation, and chemotherapy results in median survival of just over a year. To escape treatment, GBM must multiply and migrate in a confined brain environment. Both of these aspects of tumor cell invasion rely on the cell's ability to volume regulate; cell division involves a stage called "pre-mitotic condensation" in which the cells shrink immediately prior to …

Nanodiamond Mediated Therapies For Prostate Cancer, Amanee Salaam

All ETDs from UAB

Enhancing therapeutic efficacy is essential for successful treatment of chemoresistant cancers such as metastatic hormone-refractory prostate cancer. Current chemotherapy regimens are plagued with issues such as toxicity, low bioavailability, and lack of specificity. To combat these issues, the feasibility of using nanodiamond particles (ND) to enhance the therapeutic efficacy of doxorubicin and resveratrol was investigated. The enhancement of chemotherapy using NDs was evaluated with three unique approaches: (1) drug mediation, (2) combination therapy, and (3) targeted drug delivery. The ND mediated doxorubicin system achieved a 50% improvement in therapeutic efficacy with over 60% cell death. The ND resveratrol combination therapy …

Measuring The Relationship Between Contextual Factors, Nurse Staffing Patterns, And Hospital Performance, Dong Yeong Shin

All ETDs from UAB

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Role Of Immunoregulatory Cytokines Il-12 And Il-23 In Skin Cancer, Tahseen H. Nasti

All ETDs from UAB

The incidence of new cases of skin cancer, which includes non-melanoma epithelial tumors and melanoma, has increased dramatically over the last few decades. Approximately 75% of all skin cancer-related deaths is due to melanoma, which is one of the most aggressive and difficult cancers to treat. The initiating events and mechanisms that influence melanoma development are not fully known, due in part to a paucity of animal models amenable to identifying new oncogenic mutations, and investigating mechanisms of immunosurveillance. Transgenic mouse models often harbor an activating mutation in a known oncogene in all somatic cells, and its widespread expression from …

Dihydrofolate Reductase Inhibitors - Applications To Chagas Disease And Dental Caries, Thao Nguyen

All ETDs from UAB

significantly influenced sex ratios by increasing the production of males when

Three-Dimensional Photography Of Facial Morphology Of African-American Children Compared To Welsh Children, Don Franklin Norris

All ETDs from UAB

The purpose of this study is to compare the facial morphology of African-American children to Welsh children using three-dimensional imaging. Materials and Methods: Three-dimensional images were captured using a stereo-photogrammatic camera system (3dMDfaceTM). 107 African-American children were imaged with the 3dMDfaceTM system and were compared with 64 Welsh children which were previously imaged using two Minolta Vivid VI900 3D laser scanners arranged in a stereo pair. The subjects were between 10 and 13 years old, presented with a normal BMI, and had no major craniofacial deformity. The images were aligned, combined and averaged using Rapidform 2006 Plus Pack 2 software …

Prevalence Of Malaria And Selected Arboviral Infections In Patients Presenting With Undiagnosed Febrile Illness In Rusinga Island, Kenya, Purity Ngina Kipanga

All Master’s Theses

Onset of uncomplicated malaria is characterized by fever, headache, joint pains, myalgia and lack of appetite. These non-specific signs and symptoms also present in patients with arthropod borne viral (arboviral) infections complicate differential diagnoses. The lack of diagnostics that can detect arboviral infections in Kenyan public hospitals coupled with malaria diagnostic tools incapable of detecting low Plasmodiumparasitemia,has led to diagnosis based on clinical symptoms only,favouring malaria diagnosis at the expense of arboviral infections detection.Investigations were conducted to detect Plasmodiumparasites undetected by microscopy and rapid diagnostic tests (RDTs) and determine Sindbis and Bunyamwera viruses neutralizing antibodies among undiagnosed febrile ill patients …

Effect Of Herbivore-Induced Plant Volatiles Of Brachiaria Brizantha On Neighbouring Maize For Chilo Partellus Management In Suba District, Homa-Bay County, Kenya, Henlay Juma Otieno Magara

All Master’s Theses

The Lepidopteran stemborer Chilo partellus is a key constraint to cereal production in most resource-poor farming systems as it causes damage to the crop, accruing up to 80%. When plants are damaged by herbivorous insects, they produce herbivore-induced plant volatiles (HIPVs) which can act as repellants for these insect pests and as attractants for organisms antagonistic to these pests (parasitic wasps and predators). Plants can also produce signals that warn other plants of impending attack. Thus, HIPVs potentially have a practical role in crop protection by directly deterring further colonization in already infested and neighbouring plants and indirectly by attracting …

Remembering The Concentration Camps: Aleksander Kulisiewicz And His Concerts Of Prisoners' Songs In The Federal Republic Of Germany, Barbara Ann Milewski

Music Faculty Works

This chapter considers the performances of Aleksander Kulisiewicz, a Polish political prisoner who composed and collected songs in the Sachsenhausen concentration camp. In the 1960s and 1970s, he would perform these works on stages across Europe, with frequent appearances in East and West Germany (in front of highly diverse audiences. When compared to other forms of musical commemoration at the time, his appearances uniquely operate somewhere in between performance and historical witnessing by building on his authentic experience and profound belief in remembrance. While Kulisiewicz’s activity evolved out of his personal Holocaust experience, musicians and composers of subsequent generations also …

Factors That Promote And Inhibit Client Disclosure Of Suicidal Ideation, Robert William Orf

Antioch University Dissertations & Theses

Approximately 36,000 people commit suicide in the U.S. each year, making it the fourth leading cause of death for adults between 18 and 65-years-old. Clients participating in psychotherapeutic treatment are at elevated risk for suicide, due to the emotional distress that drives their entry into psychotherapy. Therapists cannot know the full extent of their clients’ risk for suicide if clients do not fully confide their thoughts and intentions. The current study sought to discover factors that inhibit and promote client disclosure of these thoughts and behaviors. The study utilized the Suicidal Ideation in Psychotherapy Questionnaire (SIPQ), a questionnaire developed for …

Threesource: Reimagining How We Collect And Share Information About Social Issues, Jen Hoyer, Stephen Macdonald

Publications and Research

This chapter examines management of information about social justice issues through discussion of the development and implementation of an online database, threeSOURCE. Managed by the Edmonton Social Planning Council, threeSOURCE is an online research database and library catalog created to help community organizations in the Canadian province of Alberta retrieve information about local social issues that they work to address. Reflections highlight issues related to creation, design, and implementation of a database, examining new ways to think about information delivery in line with the core values of our profession.

Exploiting Fluencies: Educational Expropriation Of Social Networking Site Consumer Training, Lucinda Rush, Dylan E. Wittkower

Libraries Faculty & Staff Publications

The idea of the digital native was based on abstraction; when we look in detail at the digital activities of high-school and college students, we see deskilling and consumer training rather than information literacy or technical fluency. Yet that training is still training, and may be adaptable in such a way that it can become a literacy—in, for example, the way militaries have mobilised skill-sets produced through gaming. We too can and should mine the narrow and profit-driven consumer training that emerging adults have undergone for kinds of inquiry and critical engagement for which they may have inadvertently been given …

Analyzing Magazine Articles, Jim Alderman

Beginning Library & Information Systems Strategies

Learn how to recognize magazine articles and choose when to use them in academic research.

Table Of Contents

Loyola of Los Angeles Law Review

No abstract provided.

The Hatch-Waxman Act's Side Effects: Precautions For Biosimilars, Anna B. Laakmann

Loyola of Los Angeles Law Review

No abstract provided.

The First Amendment Structure For Speakers And Speech, Charles W. "Rocky" Rhodes

Seton Hall Law Review

No abstract provided.

Nonnutritive Sweetener And Weight Management: A Potential Paradox In Modern Dieting, Katharine Mary Wright

UNF Graduate Theses and Dissertations

Obesity is a serious health concern in modern society. One way to reduce caloric intake is with nonnutritive sweeteners (NNS). However, recent research suggests they may be compounding the obesity problem. Nonnutritive sweeteners have been linked to increased body mass in a few studies and may be a barrier to effective weight management for some individuals.

Under the framework of the health belief model, the research question was: Does this pattern of NNS-BMI covariance exist in young adults at the University of North Florida and, if so, are there other dietary or activity differences that might partially explain this relationship? …

Temperament And Personality Traits As Predictors Of Preschool Odd Symptoms, Longitudinal Course, And Impairment, Brittany L. Zastrow

Theses and Dissertations--Psychology

Oppositional Defiant Disorder (ODD) is commonly conceptualized as a disorder of negative affect and low effortful control. Currently, it is unclear whether temperament and personality traits associated with negative affect and effortful control can be useful assessment tools for identifying ODD early during development. This study examined the relationship between temperament and personality traits and ODD in a clinical sample of preschoolers. Results suggest that, at this age, temperament and personality traits of negative affect and neuroticism and effortful control and conscientiousness/agreeableness are not associated with one another. High negative affect, low conscientiousness, and low agreeableness were all specifically …

Individualized Consideration: Poverty Countermeasure, Lawrence Wilson

Walden Dissertations and Doctoral Studies

Despite more than $1 trillion spent annually on poverty remediation, impoverishment in the United States persists unabated. With a U.S. poverty rate greater than 10% for more than 4 decades, economics are neither poverty's cause nor cure. As such, non-economic poverty remedies require exploration and expansion. Linking greater leadership and poverty theories, this non-experimental, cross sectional, quantitative, survey-based research effort correlated individualized consideration's (IC) practice with collegiate athlete graduation rates in order to identify and isolate possible leadership based social poverty remediation measures. Leveraging a two-stage random sample, this research effort correlated student athlete Multi-Factor Leadership Questionnaire (form 5X) responses …

Reliability Analysis For Chain Topology Wireless Sensor Networks With Multiple-Sending Transmission Scheme, Jie Cai, Xiaoyu Song, Jinyuan Wang, Ming Gu

Electrical and Computer Engineering Faculty Publications and Presentations

Reliability analysis is a key problem in wireless sensor networks (WSNs). The primary contribution of this paper is an in-depth study of the reliability of a chain topology wireless sensor network with multiple-sending scheme. We study the wireless link reliability for the fading channels. The node energy availability for the source and relay nodes is investigated in terms of the limited node energy. The instantaneous network reliability and the mean time to failure are derived. Finally, the initial node energy allocation scheme is proposed to balance the lifetime of each sensor node, thus reducing the total energy consumption. The simulation …

A Consideration Of Tracking Within A Bounded Educational System, Scott David Ripley

Walden Dissertations and Doctoral Studies

American education is built upon a cultural paradigm of equality and access. Tracking students into homogenous classes based on prior academic performance could disadvantage lower-achieving students, thereby reinforcing inequality. The problem in the study district is that homogenous tracking was implemented, yet the system had not been evaluated within the context of implementation. The purpose of this qualitative case study was to examine educators' perceptions of the practice of tracking. Bandura and Maslow's social cognitive theory provided the conceptual framework and Dewey's beliefs on social justice and a spirit of equity provided the theoretical foundation. Open-ended narrative questionnaires were disseminated …

Refining Computerized Physician Order Entry Initiatives In An Adult Intensive Care Unit, Chevita Fuller

Walden Dissertations and Doctoral Studies

Computerized physician order entry (CPOE) is used in healthcare organizations to improve workflow processes and transcription, as well as to prevent prescribing errors. Previous research has indicated challenges associated with CPOE for end-users that predispose patients to unsafe practices. Unsafe CPOE practices can be detrimental within the intensive care unit (ICU) setting due to the complexity of nursing care. Consequently, end-user satisfaction and understanding of CPOE and electronic health record (EHR) functionality are vital to avoid error omissions. CPOE initiatives should be refined post system implementation to improve clinical workflow, medication processes, and end-user satisfaction. The purpose of this quality …

Symbolic Imprisonment, Grief, And Coping Theory: African American Women With Incarcerated Mates, Avon Marie Hart-Johnson

Walden Dissertations and Doctoral Studies

African American men have been incarcerated at unprecedented rates in the United States over the past 30 years. This study explored how African American females experience adverse psychosocial responses to separation from an incarcerated mate. The purpose of this qualitative grounded theory (GT) study was to construct a theory to explain their responses to separation and loss. Given the paucity of literature on this topic, helping professionals may not understand this problem or know how to support these women. Disenfranchised grief and the dual process model of bereavement were used as a theoretical lens for this study. Data were collected …

A Correlational Analysis Of Empowerment And Experience With Resistance To Change, Rita Elizabeth Burgess

Walden Dissertations and Doctoral Studies

Despite more than 60 years of research about the nature of change, resistance to change remains a problem across industries. Health care leaders have limited knowledge of how health care managers' perceptions of empowerment, years of experience, and resistance to change (RTC) relate. The purpose for this nonexperimental correlational study was to examine the relationship between empowerment, years of experience, and RTC among managers via an online survey. The theoretical framework incorporated Kanter's structural empowerment theory and Kotter's change theory. The sample included 245 out of 1,181 health care managers from Veterans Administration (VA) hospitals in the New York metropolitan …

Cupola, 2014, Western New England University

Yearbooks

Western New England University was founded in 1919 as the Springfield Division of Northeastern University. The senior yearbooks bore the name of Northeastern University in some way until 1953. The yearbook was given its present day title, The Cupola, in 1961. Yearbooks contain photos of graduating seniors, campus events, student clubs and organizations, faculty and staff, athletic teams and events, and other memorable occasions from the academic year.

Advanced Property Issues In Family Law: An Annotated Bibliography, Travis Mcdonald, Nancy Levit

Faculty Works

This bibliography covers law review articles published, for the most part, after 2006 on property issues within the context of family law. Articles for which the title is self-explanatory or that concern only a single case, state, or statute are cited, but not annotated.

Athenaeum Series Events, 2006-2014, D'Amour Library

Athenaeum Series

No abstract provided.

Oral Health Knowledge, Attitudes, And Practices Among Secondary School Students In Nigeria, Johnson John Omale

Walden Dissertations and Doctoral Studies

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Envisioning A Better Body, Samantha Dempsey 13 Il, Risd Xyz

RISD XYZ Fall/Winter 2014/2015: The Body

Virgil Wong 05 IL is building on a lifelong fascination with the human body to develop apps that help us manage our own health.