Digital Commons Network^™

An Efficient Algorithm To Explore Liquid Association On A Genome-Wide Scale, Tina Gunderson, Yen Yi Ho

Faculty Publications

Background: The growing wealth of public available gene expression data has made the systemic studies of how genes interact in a cell become more feasible. Liquid association (LA) describes the extent to which coexpression of two genes may vary based on the expression level of a third gene (the controller gene). However, genome-wide application has been difficult and resource-intensive. We propose a new screening algorithm for more efficient processing of LA estimation on a genome-wide scale and apply its use to a data set. Results: On a test subset of the data, the fast screening algorithm achieved >99.8 agreement with …

Par Izmaiņām Bankas Citadele Padomē, Citadele

Documents

No abstract provided.

Interaction Quench Induced Multimode Dynamics Of Finite Atomic Ensembles, Simeon I. Mistakidis, L. Cao, P. Schmelcher

Physics Faculty Research & Creative Works

The Correlated Non-Equilibrium Dynamics Of Few-Boson Systems In One-Dimensional Finite Lattices Is Investigated. Starting From Weak Interactions We Perform A Sudden Interaction Quench And Employ The Numerically Exact Multi-Layer Multi-Configuration Time-Dependent Hartree Method For Bosons To Obtain The Resulting Quantum Dynamics. Focusing On The Low-Lying Modes Of The Finite Lattice We Observe The Emergence Of Density-Wave Tunneling, Breathing And Cradle-Like Processes. In Particular, The Tunneling Induced By The Quench Leads To A 'global' Density-Wave Oscillation. The Resulting Breathing And Cradle Modes Are Inherent To The Local Intrawell Dynamics And Connected To Excited-Band States. Moreover, The Interaction Quenches Couple The Density-Wave …

The Weekly Challenger, November 27, 2014, The Weekly Challenger, Et Al

Weekly Challenger Newspaper Collection

The November 27, 2014, issue of The Weekly Challenger.

People's Bank Of China And Hong Kong Monetary Authority Renewed Currency Swap Agreement (11/27/2014), Hong Kong Monetary Authority

Documents

Other Relevant Crises: European Sovereign Debt Crisis (2008 - 2012)

Inhibition Of Osteoclastogenesis And Inflammatory Bone Resorption By Targeting Bet Proteins And Epigenetic Regulation, Kyung-Hyun Park-Min, Elisha Lim, Min Joon Lee, Sung Ho Park, Eugenia Giannopoulos, Anna Yarilina, Marjolein Van Der Meulen, Baohong Zhao, Nicholas Smithers, Jason Witherington, Kevin Lee, Paul P. Tak, Rab K. Prinjha, Lionel B. Ivashkiv

Publications and Research

Emerging evidence suggests that RANKL-induced changes in chromatin state are important for osteoclastogenesis, but these epigenetic mechanisms are not well understood and have not been therapeutically targeted. In this study we find that the small molecule I-BET151 that targets bromo and extra-terminal (BET) proteins that “read” chromatin states by binding to acetylated histones strongly suppresses osteoclastogenesis. I-BET151 suppresses pathologic bone loss in TNF-induced inflammatory osteolysis, inflammatory arthritis, and post-ovariectomy models. Transcriptome analysis identifies a MYC-NFAT axis important for osteoclastogenesis. Mechanistically, I-BET151 inhibits expression of the master osteoclast regulator NFATC1 by suppressing expression and recruitment of its newly identified upstream regulator …

The Cord (November 26, 2014)

The Cord

No abstract provided.

November 26, 2014 Cal Poly Report, Public Affairs Office

Cal Poly Report

No abstract provided.

Culture In Crisis: The English Novel In The Late Twentieth Century, Michael F. Harper

Scripps Faculty Books

Culture in Crisis begins with political and social history at the moment of the election of Margaret Thatcher. Many saw in this event the dissolution of the ideal of the liberal State once believed to be shared by both the Left and the Right. Ranging widely over such writers as Anthony Powell, John LeCarre, Samuel Selvon, Salman Rushdie, and Margaret Drabble, Harper examines various responses to this “crisis” which he shows to have roots in a pernicious ideal of “Englishness” going back many generations. With considerable skill and a masterful grasp of books and ideas, he presents the novel as …

The Anchor, Volume 128.12: November 26, 2014, Hope College

The Anchor: 2014

The Anchor began in 1887 and was first issued weekly in 1914. Covering national and campus news alike, Hope College’s student-run newspaper has grown over the years to encompass over two-dozen editors, reporters, and staff. For much of The Anchor's history, the latest issue was distributed across campus each Wednesday throughout the academic school year (with few exceptions). In recent years The Anchor moved to monthly print issues and a more frequently updated website. The Anchor is now published in print twice per academic semester. Occasionally, the volume and/or issue numbering is irregular.

Characterization Of 10,12-Pentacosadiynoic Acid Langmuir–Blodgett Monolayers And Their Use In Metal–Insulator–Metal Tunnel Devices, Saumya Sharma, Mohamad Khawaja, Manoj K. Ram, D. Yogi Goswami, Elias Stefanakos

College of Engineering Publications

The characterization of Langmuir–Blodgett thin films of 10,12-pentacosadiynoic acid (PDA) and their use in metal–insulator–metal (MIM) devices were studied. The Langmuir monolayer behavior of the PDA film was studied at the air/water interface using surface tension–area isotherms of polymeric and monomeric PDA. Langmuir–Blodgett (LB, vertical deposition) and Langmuir–Schaefer (LS, horizontal deposition) techniques were used to deposit the PDA film on various substrates (glass, quartz, silicon, and nickel-coated film on glass). The electrochemical, electrical and optical properties of the LB and LS PDA films were studied using cyclic voltammetry, current–voltage characteristics (I–V), and UV–vis and FTIR spectroscopies. …

Microbial Diversity In A Venezuelan Orthoquartzite Cave Is Dominated By The Chloroflexi (Class Ktedonobacterales) And Thaumarchaeota Group I.1c, Hazel A. Barton, Juan G. Giarrizzo, Paula Suarez

KIP Articles

The majority of caves are formed within limestone rock and hence our understanding of cave microbiology comes from carbonate-buffered systems. In this paper, we describe the microbial diversity of Roraima Sur Cave (RSC), an orthoquartzite (SiO4) cave within Roraima Tepui, Venezuela. The cave contains a high level of microbial activity when compared with other cave systems, as determined by an ATP-based luminescence assay and cell counting. Molecular phylogenetic analysis of microbial diversity within the cave demonstrates the dominance of Actinomycetales and Alphaproteobacteria in endolithic bacterial communities close to the entrance, while communities from deeper in the cave are dominated (82–84%) …

Today - November 26, 2014, Loma Linda University Health

TODAY

Inside this issue:

-- Nichole Nordeman headlines ThankSharing Concert and Food Drive held in Redlands
-- Loma Linda University receives national grant to train entry-level health care workers
-- Reunion celebrates School of Dentistry's five years of successful PNAM-augmented cleft lip and palate repairs
-- 'Hiring blitz' brings 128 nurses on board
-- Grateful mother and March of Dimes volunteer thanks LLUMC
-- Pedestrian bridge over Campus Street opens
-- LLU dental hygiene students run Relay for Life
-- Annual colloquium trains faculty to enhance learning
-- Last flight of the big gray owl disrupts Southwestern adventure for Global Health …

Unraveling Cultural Knots: Exploring Narratives Of Intercultural Marriages Between Mexicans And Americans, Adrianna Renata Valenzuela

Theses and Dissertations

Narratives function to help us make decisions about what we do in our lives and in the lives of others. This study focuses on the intercultural marriages of three women who share Mexican and American cultures. Being a wife of a native Mexican, I proceed to examine the stories of how these three women were able to preserve or merge their cultural identity in the marriage and how they coped with the differences based on the following themes: culture, religion, and traditions. I composed three narratives based on the experiences of these women and incorporated an analysis of my findings …

Dove V. Parham: Desegregation In The Dollarway School District, Kevin Sinclair

Theses and Dissertations

This study examines the Dove v. Parham school desegregation case that was heard on December 16, 1959, in the United States District Court, Eastern District of Arkansas, Western Division with Judge J. Smith Henley presiding. Attorney George Howard Jr. had brought forth the lawsuit on behalf of three African American students who were denied transfer to the all-white Dollarway School District. The tactic of massive resistance had failed to stop any integration attempts in the state and was replaced by minimal compliance. The Dollarway School District chose to use pupil placement laws to avoid integration. By using transcripts from the …

Reflective Assessment: Using Reflection And Portfolios To Assess Student Learning In A Writing Center, Kelsie Hope Walker

Theses and Dissertations

As writing centers continue to petition for status, funding, and authority on university and college campuses, writing center research and assessment practices continue to evolve. Within the last 10 years, writing center administrators have turned to assessing the writing center based on student learning outcomes (SLOs). This research summarizes the assessment history of writing centers and then proposes a pilot study that uses portfolios and reflection as a way to assess student learning in a writing center on a metropolitan, four-year university campus. This research also discusses the pilot study in terms of future research and implications.

Alternative Approaches To Correction Of Malapropisms In Aiml Based Conversational Agents, Walter A. Brock

CCAC Theses and Dissertations

The use of Conversational Agents (CAs) utilizing Artificial Intelligence Markup Language (AIML) has been studied in a number of disciplines. Previous research has shown a great deal of promise. It has also documented significant limitations in the abilities of these CAs. Many of these limitations are related specifically to the method employed by AIML to resolve ambiguities in the meaning and context of words. While methods exist to detect and correct common errors in spelling and grammar of sentences and queries submitted by a user, one class of input error that is particularly difficult to detect and correct is the …

High-Stakes Evaluation: Five Years Later, Tonya Rutherford-Hemming, Suzan Kardong-Edgren, Teresa Gore, Patricia K. Ravert, Mary Anne Rizzolo

Faculty Publications

This article compares the International Nursing Association of Clinical Simulation and Learning (INACSL) memberships' thoughts and discussions about the use of simulation for high- stakes evaluation in nursing education to a similar town hall discussion, five years ago. Data on the topic of high-stakes testing were collected through a survey before the INACSL conference in June 2014. During a town hall meeting at the conference, the survey data was presented, attendees shared their thoughts and reacted to prepared comments by selected simulation leaders. Half of the town hall attendees favored high stakes testing before the survey findings and discussion. This …

Saying Thanks Isn’T Always Simple, Melody Bowdon

UCF Forum

Tomorrow is Thanksgiving, and people all over the country will gather around tables with loved ones to express thanks for time together, getting through another year, and green bean casserole.

Giving Thanks, Michelle Morrissey

UNH Today Archive

No abstract provided.

A Vision For Change In Bioscience Education: Building On Knowledge From The Past, Nancy J. Pelaez, Trevor R. Anderson, Samuel N. Postlethwait

PIBERG Publications

High quality undergraduate education is central to the success of all life scientists. Several major bioscience educational issues are the targets of much debate, research, funding, publications, and reports (e.g. Vision and Change). Surprisingly, these issues are considered by modern bioscience instructors as unresolved despite historical reports that claim the contrary. Here we illustrate with evidence how, more than 50 years ago, Sam Postlethwait successfully instituted strategies to address several issues in plant biology education with his audio-­‐tutorials. These strategies succeeded in individualizing instruction of students with diverse educational backgrounds in large classes, incorporating authentic and active learning, integrating lab …

Backfolding Of Wormlike Chains Confined In Nanochannels, Abhiram Muralidhar, Douglas R. Tree, Kevin D. Dorfman

Faculty Publications

Using pruned-enriched Rosenbluth method (PERM) simulations of a discrete wormlike chain model, we provide compelling evidence in support of Odijk’s prediction of two distinct Odijk regimes for a long wormlike chain confined in a nanochannel. In both cases, the chain of persistence length lp is renormalized into a series of deflection segments of characteristic length D2/3lp1/3, where D is the channel size. In the first (classic) Odijk regime, these deflection segments are linearly ordered. In the second Odijk regime, thin, long wormlike chains can backfold at a length scale quantified by the global persistence length. We …

European Court Of Human Rights - Extradition - Inhuman Or Degrading Treatment Or Punishment, Soering Case, 161 Eur. Ct. H.R. (Ser. A) (1989), David L. Gappa

Georgia Journal of International & Comparative Law

No abstract provided.

Panel Iii--General Discussion, Georgia Journal Of International And Comparative Law

Georgia Journal of International & Comparative Law

No abstract provided.

The Inter-American System For The Promotion And Protection Of Human Rights, David J. Padilla

Georgia Journal of International & Comparative Law

No abstract provided.

United States Ratification Of The United Nations Covenants, Richard B. Lillich

Georgia Journal of International & Comparative Law

No abstract provided.

Range Of Horizontal Transport And Residence Time Of Nitrate In A Mature Karst Vadose Zone, Jiri Kamas, Jiri Bruthans, Helena Vysoka, Miroslav Kovařík

International Journal of Speleology

Nitrate concentrations in drips in Amaterska, Spolecnak, and Holstejnska caves situated below a 25 to 120 m thick vadose zone in the Moravian Karst, Central Europe were studied during several periods from 1992. Each cave runs below a land-use boundary between fertilized lands and forest, which enabled study of the range of horizontal components of nitrate transport in the vadose zone. Parts of the fertilized land were turned into grassland in 1998 and 2003, and the cave drips were sampled both prior and after the changes in land use. The mean residence time of nitrate is - 30 m thick …

Hairy Stalagmites, A New Biogenic Root Speleothem From Botswana, Gerhard C. Du Preez, Paolo Forti, Gerhard Jacobs, Anine Jordaan, Louwrens Tiedt

International Journal of Speleology

Ngamiland in northwestern Botswana hosts the Gcwihaba Caves which present unique subterranean environments and host speleothems never before recorded. Cave atmospheric conditions can be extreme with temperatures as high as 28°C and relative humidity nearing 99.9%. Within Dimapo and Diviner’s Caves peculiar root speleothems that we named ‘Hairy Stalagmites’ were found. These stalagmites are closely associated with the roots of Namaqua fig (Ficus cordata) trees that enter the cave environment in search of water. Pieces of broken stalagmites were sampled from Dimapo Cave for further investigations. Stereo and electron microscopy revealed that the Hairy Stalagmites consist of multiple …

High-Resolution Digital 3d Models Of Algar Do Penico Chamber: Limitations, Challenges, And Potential, Ivo Silvestre M.Sc., José I. Rodrigues Phd, Mauro Figueiredo Phd, Cristina Veiga-Pires Phd

International Journal of Speleology

The study of karst and its geomorphological structures is important for understanding the relationships between hydrology and climate over geological time. In that context, we conducted a terrestrial laser-scan survey to map geomorphological structures in the karst cave of Algar do Penico in southern Portugal. The point cloud data set obtained was used to generate 3D meshes with different levels of detail, allowing the limitations of mapping capabilities to be explored.

In addition to cave mapping, the study focuses on 3D-mesh analysis, including the development of two algorithms for determination of stalactite extremities and contour lines, and on the interactive …

Unmanned Aerial Vehicles: Legitimate Weapon Systems Or Unlawful Angels Of Death?, Michael J. Deegan

Pace International Law Review

Since the invasion of Afghanistan, the United States has utilized Unmanned Aerial Vehicles (UAVs) to locate, surveil and kill members of the Taliban, Al-Qaeda and its associated forces. Such killings have decimated the leadership of these groups and disrupted their operations. However, there are collateral effects from UAV killings including civilian deaths. These deaths increase resentment and hatred toward the US, which is channeled by terrorist groups to recruit new members and for local support. Moreover, targeted killings outside a combat zone have political and diplomatic consequences. This paper argues that the current uses of UAV are legal under international …