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2014-July-14-Dr. Aruna Kilaru News, University Marketing And Communications, East Tennessee State University

ETSU News

No abstract provided.

Design, Synthesis And Evaluation Of Small Molecules As Inhibitors Of Plasminogen Activator Inhibitor-1, Darshani Avanthi Weerakoon

Master's Theses and Doctoral Dissertations

Plasminogen activator inhibitor type-1 (PAI-1) is a member of the serine protease inhibitor (serpin) superfamily. Excessive levels of PAI-1 inhibit urokinase-type plasminogen activator (uPA) and tissue-type plasminogen activator (tPA), which regulates fibrinolysis as well as the development of different pathological diseases like obesity, metabolic syndrome, tumor invasion and metastasis, and coronary heart disease. Currently, there is no Food and Drug Administration approval for inactivating higher levels of PAI-1. Therefore, PAI-1 is considered an attractive drug target. Due to PAI-1’s different structural conformations and multiple binding domains, development of PAI-1 inhibitors is a challenging situation. In this research study, we describe …

Inter- And Intralimb Adaptations To A Sensory Perturbation During Activation Of The Serotonin System After A Low Spinal Cord Transection In Neonatal Rats, Misty M. Strain, Sierra D. Kauer, Tina Kao, Michele R. Brumley

Publications and Research

Activation of the serotonin system has been shown to induce locomotor activity following a spinal cord transection. This study examines how the isolated spinal cord adapts to a sensory perturbation during activation of the serotonergic system. Real-time and persistent effects of a perturbation were examined in intact and spinal transected newborn rats. Rats received a spinal surgery (sham or low thoracic transection) on postnatal day 1 and were tested 9 days later. At test, subjects were treated with the serotonergic receptor agonist quipazine (3.0 mg/kg) to induce stepping behavior. Half of the subjects experienced range of motion (ROM) restriction during …

"Nigger": A Critical Race Realist Analysis Of The N-Word Within Hate Crimes Law, Shayne E. Jones, Gregory S. Parks

Criminology Faculty Publications

On a 2005 summer morning, Nicholas “Fat Nick” Minucci (White) beat Glenn Moore (Black) with a baseball bat and robbed him. During the assault, Minucci repeatedly screamed the N-word. At trial, Minucci’s attorney argued that he had not committed a hate crime. The essence of the defense’s argument was that Minucci’s use of the N-word while assaulting and robbing Moore was not indicative of any bias or prejudice. The defense went on to indicate that Minucci had Black friends, was immersed in Black culture, and employed the N-word as part of his everyday vocabulary. Two Black men—Gary Jenkins (hip hop …

Comorbidity Of Infectious Diseases And Anxiety Disorders In Adults And Its Association With Quality Of Life: A Community Study, Cornelia Witthauer, Andrew T. Gloster, Andrea Hans Meyer, Renee D. Goodwin, Roselind Lieb

Publications and Research

Objective: Infectious diseases and anxiety disorders are common and both are associated with substantial burden to individual, families, and society. A better understanding of their association may be helpful in explicating possible etiological mechanisms related to both. The goal of the current study was to investigate the relationship between specific infectious diseases and anxiety disorders among adults in the community, and to examine whether the co-occurrence of the two is associated with poorer quality of life compared to subjects with one or neither condition.

Methods: We used data from the 1998 German Mental Health survey with 4181 subjects aged 18–65. …

State V. Hughes Appellant's Reply Brief Dckt. 41365

Idaho Supreme Court Records & Briefs, All

No abstract provided.

Informing Flood Plain Wetland Restoration Using Amphibian Monitoring, Ashley Vanderham

School of Natural Resources: Dissertations, Theses, and Student Research

Wetlands are among the most important and complex ecosystems in the world. They contribute to nutrient cycling, the hydrologic cycle, and provide critical habitat for many plants, fish, and wildlife. Channelization of Missouri River resulted in the loss of many floodplain wetlands. Despite ongoing restoration efforts, there are few ecologically-based performance guidelines, and managers need methods to quantify and assess the success of restored riverine wetland systems.

In 2008 a multi-institutional herpetofauna monitoring project, funded by the U.S. Army Corps of Engineers, was initiated in four states (Kansas, Missouri, Iowa, and Nebraska). The main goal of the project is to …

This Is Sparta! Mediated Mythology As Pedagogy In 300, Adam W. Tyma

Communication Faculty Publications

Popular films continue to replace history courses as the source of truth with regard to important events or eras. 300, in its interpretation of the Battle of Thermopylae, based on the graphic novel by Frank Miller, is an example of this trend. Rather than adhering to the presented historical facts of the event, 300 offers a hyperreal interpretation of the battle and the societies that surrounded it, infusing contemporary hegemonic ideologies regarding sexuality, classism, and race into a mediated discourse that presents the spectacle of the film as reality. This essay examines the narratives that are presented within the film, …

Advances In Aquatic Target Localization With Passive Sonar, John Thomas Gebbie

Dissertations and Theses

New underwater passive sonar techniques are developed for enhancing target localization capabilities in shallow ocean environments. The ocean surface and the seabed act as acoustic mirrors that reflect sound created by boats or subsurface vehicles, which gives rise to echoes that can be heard by hydrophone receivers (underwater microphones). The goal of this work is to leverage this "multipath" phenomenon in new ways to determine the origin of the sound, and thus the location of the target. However, this is difficult for propeller driven vehicles because the noise they produce is both random and continuous in time, which complicates its …

Emission Of Volatile Organic Compounds After Land Application Of Cattle Manure, Bryan Woodbury, John E. Gilley, David B. Parker, David B. Marx, Daniel N. Miller, Roger A. Eigenberg

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Beef cattle manure can serve as a valuable source of nutrients for crop production. However, emissions of volatile organic compounds (VOCs) after land application may pose an odor nuisance to downwind populations. This study was conducted to evaluate the effects of land application method, diet, soil moisture content, and time since manure application on VOC emissions. Manure was collected from feedlot pens where cattle were fed diets containing 0, 10, or 30% wet distillers grains with solubles (WDGS). Land application methods included surface-applying manure (i.e., no-tillage) or incorporating manure using disk tillage. The effects of soil moisture content on VOC …

The Effects Of Opedix < Sup > Tm < / Sup > Knee Support System, Philip Mathew

Theses and Dissertations

INTRODUCTION: Knee supports are often employed to decrease adductor angle and/or adductor moment and thus medial knee joint loading in persons with medial knee osteoarthritis. It is compelling that these gait alterations would also be considered beneficial in healthy individuals from a prophylactic application. While the Opedix product was designed specifically as a knee support system, in the present study lower extremity kinematic chain with emphasis on hip and knee were investigated.

PURPOSE: The purpose of this study was to test Opedix garments and describe the changes in sagittal (X), frontal (Y), and transverse (Z) planes for both kinematic and …

Mentoring High School Students, Robin L. Cooper

Kaleidoscope

Dr. Robin Cooper is a faculty member in the Department of Biology and teaches physiology and neurobiology courses at the University of Kentucky. His research is in comparative physiology. He received a double major with a B.S. in Chemistry and Zoology from Texas Tech in 1983 and a PhD in Physiology from Texas Tech Medical School in 1989. He has had postdoctoral training in Switzerland and Canada for 7 years before joining the University of Kentucky in 1996.

Democratizing The Food System- The Food Policy Council Movement, Garrett Spear

Kaleidoscope

The increasing complexity of our modern food system has changed the landscape of American agriculture and diet, and has increasingly consolidated decision-making abilities in a concentrated group of organizations. Local food movements are re-appropriating their food supply chains through a variety of methods, including the democratic-minded food policy council organization. Food policy councils organize community stakeholders into a network of organizations which can collectively grapple with food issues affecting and on behalf of the local community. This study consisted of research on the history and methods of the food policy council movement, directed ultimately at the council-less context in Lexington …

Satire And Stoicism: Pieter Bruegel The Elder's Triumph Of Death, Susan K. Gisselberg

Kaleidoscope

In Bruegel and the Creative Process, 1559 – 1563, Margaret Sullivan explains how the religious and political disorder of the Reformation in the Netherlands influenced Pieter Bruegel’s most original works, including The Triumph of Death. During this period, Bruegel combined classical elements and vernacular traditions. As a result of this process, he was able to depict similar imagery to his contemporaries, yet convey a vastly different concept. In a review, Todd Richardson argued that her claim relied heavily on classical literary sources with inadequate visual evidence in the work itself, and her correlations to antiquity rely solely on the …

Medical School Watercooler Newsletter - July 13, 2014, Lindsey Lyle

Watercooler Newsletter

This is the July 13, 2014 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler.

Contents Include:

• to Visit USA Biomedical Library
• USA Medical Student Participating in Research Program in Birmingham
• Medical School Graduates Begin Residency Training
• Med School Café - Expert Advice for the Community

Amphibian Contributions To Ecosystem Services, Daniel J. Hocking, Kimberly J. Babbitt

New Hampshire Agricultural Experiment Station Publications

Ecosystems provide essential services for human society, which include provisioning, regulating, cultural, and supporting services. Amphibians provide provisioning services by serving as a food source for some human societies, especially in Southeast Asia. They also serve as models in medical research and provide potential for new pharmaceuticals such as analgesics and anti-viral drugs derived from skin secretions. Amphibians contribute to regulating services by reducing mosquito recruitment from ephemeral wetlands, potentially controlling other pest species, and indirectly through predation of insect pollinators. Often neglected, ecosystems also provide cultural services to human societies that increase the quality of human life through recreation, …

Implications Of Vertebral Degenative Disease And Vertebral Ligamentous Ossification In Native Populations Of The Lower Tennessee River Valley, Sarah Ann Boncal

Theses and Dissertations

Cervical vertebrae are an effective biomechanical proxy for understanding physical activities of a populace due to the osteological reactivity of nuchal muscle use to extensive weight and pressure. Differentiation in the distribution of osteophytosis (OPL), osteoarthritis (OA), and ossification of the ligamentum flavum (OLF) along the cervical vertebrae may indicate particular biomechanical stresses and/or burden-bearing differences between subsistence strategies.

A collection of 287 pre-Columbian Native American individuals (N = 854 vertebrae) was analyzed for presence and severity of OPL, OA and OLF. The sample consists of remains from six archaeological sites located in the lower Tennessee River Valley: three sites …

Heidegger And The Ethics Of The Earth: Eco-Phenomenology In The Age Of Technology, Tara Kennedy

Philosophy ETDs

Martin Heidegger came to see the history of Western metaphysics as a series of ontotheological epochs. These epochs, he argues, culminate in the age informed by the metaphysics of Friedrich Nietzsche. According to this ontotheological paradigm, entities are nothing more than meaningless resources to be optimized. This paper argues that this is the source of the environmental crises we face. In order to see our way through and beyond this nihilistic ontotheological age, we must recognize the ontological source of all existence, that which Heidegger called being as such. The philosophical tradition of phenomenology offers us an ideal method for …

A Standalone High Frequency Receiver System, Orlando Leone Jr.

Electrical and Computer Engineering ETDs

The High Frequency Receiver System (HFRS) is a mobile, autonomous, Linux-based RF recording system that is designed to pick up ionosonde sounding signals from 1—10 MHz. Systems are designed for quick deployment and capable of remaining deployed in the field for up to a month. The design motivation was for ionospheric sounding campaigns in New Mexico organized by the Air Force Research Labora- tories (AFRL). The systems are calibrated to selected sites and thus require Radio Frequency Interference (RFI) characterization of the sites. The project includes building and using four standalone systems with associated power, antenna, RF, and remote control …

Eva'lution In Fandangos, Fiestas, And Flamenco: Adding To The Repertoire Of Chicano Expressive Arts, Trisha Venisa Martinez

American Studies ETDs

This study seeks to explain this curious and unknown connection of Albuquerque flamenco to Eva Encinias-Sandoval and the dance traditions of Nuevomexicanos. I seek to identify the history and social impact of this rich and distinct New Mexico flamenco tradition by tracing the development of Encinias-Sandoval's career and the establishment of her now world-class flamenco arts program, offered through the University of New Mexico's Dance and Theatre Department, as well as thorough affiliates and organizations of the National Institute of Flamenco. More specifically, my thesis describes how Eva Encinias-Sandoval built and continues to anchor this inspiring expressive art form in …

Bayesian Partially Ordered Probit And Logit Models With An Application To Course Redesign, Xueqi Wang

Mathematics & Statistics ETDs

Large entry-level courses are commonplace at public 2- and 4-year institutions of higher education (IHEs) across the United States. Low pass rates in these entry-level courses, coupled with tight budgets, have put pressure on IHEs to look for ways to teach more students more effectively at a lower cost. Efforts to improve student outcomes in such courses are often called ``course redesigns.' The difficulty arises in trying to determine the impact of a particular course redesign; true random-controlled trials are expensive and time-consuming, and few IHEs have the resources or patience to implement them. As a result, almost all evaluations …

Pathologizing And Criminalizing Intoxication: Addiction, Psychoactive Drugs, And The Ideological Underpinnings Of The War On Drugs, David Korostyshevsky

History ETDs

Since the Enlightenment, Anglo-American temperance thinkers—who were usually clergymen and physicians—have expressed broader concerns about intoxication and addiction with rhetoric that simultaneously pathologized and criminalized the unsanctioned use of psychoactive substances. During the first half of the eighteenth century, a period known as the Gin Craze, rising levels of urban drunkenness in England came under the sustained gaze of temperance-minded doctors and churchmen, who used a shared language of contagion, disease, and slavery to problematize intoxication simultaneously as a medical and criminal condition. Building on Enlightenment English temperance thought, which was transferred into the United States by physician Benjamin Rush, …

Development Of Novel Synthetic Methods For Size-Tunable Synthesis Of Superparamagnetic Iron Oxide Nanoparticles, Erika Vreeland

Chemical and Biological Engineering ETDs

The properties of magnetic nanoparticles vary dramatically with size, so reproducibly controlling size is critical for practical applications. This is particularly true when moving into clinical settings, where regulatory approval requires demonstrated reproducibility in efficacy that can only be achieved with excellent size control. A number of methods for the synthesis of magnetic nanoparticles have been published, although the thermal decomposition of iron(III) precursors in organic solvents has been shown to yield high quality particles with low shape and size dispersity. Currents methods lack reproducibility resulting from non-stoichiometric starting materials, and reliance on reaction parameters, such as temperature ramp rate, …

Moderate Fetal Alcohol Exposure, The Nucleus Accumbens, And Alcohol Consumption In Adulthood, James Rice

Psychology ETDs

Recent findings using a moderate prenatal alcohol consumption model in rats found that male offspring had reduced dendritic fields in medium spiny neurons of the nucleus accumbens (NAc). These results suggest that moderate fetal alcohol exposure (FAE) leads to long-lasting alterations in brain regions involved in reward processing that could lead to abnormal behavior related to ethanol (EtOH) in adulthood. Here, five experiments were carried out to establish the extent to which moderate FAE leads to increased EtOH consumption in adulthood, how functional and structural alterations in the NAc are related to EtOH consumption, and whether moderate FAE has any …

The Last Apache "Broncho": The Apache Outlaw In The Popular Imagination, 1886-2013, Leah Candolin Cook

History ETDs

This study examines the American mythmaking of late-nineteenth- and early-twentieth-century Apache 'renegades' and their post—Apache Wars counterpart the Apache 'bronchos' in popular culture and memory. The idea of the 'broncho' Apache created fear, insecurity, and cautionary folklore for residents of the American Southwest and northern Mexico from 1886—1930s. Over time, white appropriations of Apaches in literature, film, and pop culture would evolve from the murderous wild 'savage,' to the sympathetic anti-hero, to the hero. This thesis connects representations of Apaches with contemporaneous American attitudes on race, masculinity, nostalgia. Although portrayals of Apaches changed over time, an underlying theme of the …

Connecting People And Place: Farmers, Resilience, And The Future Of Smallholder Farms In Albuquerque, Crystiana Baca-Bosiljevac

Geography ETDs

This paper compares scholarly concepts of resilience with primary factors influencing Albuquerque's smallholder farmers' decisions to continue farming. In doing so, it highlights the voices of local farmers and critically examines the scope and limitations of resilience theory. Although resilience theory has gained popularity as a tool for understanding complex social-ecological systems, recent scholarship questions the applicability of resilience to social systems. In particular, questions have been raised as to whether current resilience theory adequately addresses issues of power and agency. By focusing on farmers as decision makers, this paper seeks to evaluate these claims by examining the utility of …

"I Don't Approve Of That Way Of Running A Family": Transient Children, Institutions, And Interventions In California Through The Great Depression And Dust Bowl, Jairo Marshall

History ETDs

This thesis studies the state of California's responses to migratory families and children during the Depression and Dust Bowl. In particular, it emphasizes the growth of several state bureaucracies during this time, including the Department of Public Health, the Department of Education, and the Youth Authority. It also engages with local nonprofit relief agencies as well as county agencies, which functioned as direct aid providers to migrants. The efforts to provide relief to migrant families are explained, as are the surrounding rhetorical frameworks used to discuss the perceived negative attributes of migrant children. These discourses influenced administrators, California residents, and …

Counterfactual Feedback And Tennis, G. Beth Birky

Health, Exercise, and Sports Sciences ETDs

Physical education teachers must consider the most effective way to deliver instruction and feedback for maximum student learning. Counterfactual feedback assists in engaging visual (internal) and auditory augmented feedback in order to create an optimal learning environment, which will produce the highest skill level in the shortest time possible (Sigrist, et al, 2011). Counterfactual feedback promotes critical thinking as it applies to the performance of a skill. Critical thinking is linked to better decision-making, reasoning, problem-solving, and reflective judgment in individuals (Lodewyck, 2009). Counterfactual feedback relies on the teacher asking a directed question as feedback after a skill performance or …

Beyond The Missions: Ethnogenesis In Colonial Paraguay, 1556-1700, Shawn Michael Austin

History ETDs

This dissertation argues that Guaraní socio-cultural practices determined what Spaniards could and could not do in colonial Paraguay. Beyond the Missions,' refers to colonial encounters outside the oft-romanticized Jesuit missions, especially within the provincial capital of Asunción. This research, therefore, complements the scholarship on the Jesuit missions by demonstrating that the Guaraní among the Spanish were just as influential as their counterparts in the missions in shaping the process by which they assumed new ethnic identities (or ethnogenesis) in Christian communities. Moreover, Guaraní social norms deeply influenced colonials and their institutions, including Blacks and the practice of African slavery. This …

Cul-De-Sac: Social Conversation Through Research And Performance, Peter J. Bennett

Theatre & Dance ETDs

Cul-De-Sac: Social Conversation Through the Lens of Jazz Dance, discusses the rise of the suburbs following the Second World War, the homophobic society of the 1950s forcing homosexual men to hide in the closet, and the role of women within the suburban community, and how the research into these social issues evolved into an evenings length piece of dance theatre told through the language of jazz dance. Jazz dance is a distinctly American art form, often overlooked on the concert stage. In this dissertation, I endeavor to prove that jazz is a style of dance capable of carrying social messages …