Digital Commons Network^™

Genetic And Mechanistic Analysis Of Rat Mammary Cancer Susceptibility., Jennifer Sanders

Electronic Theses and Dissertations

Breast cancer is a complex disease, which is influenced by genetic, epigenetic and environmental components. Genetic susceptibility to breast cancer is made up of high, moderate and low penetrance alleles. High and moderate penetrance alleles are rare and constitute only a small percentage of the genetic susceptibility. Most variation in genetic susceptibility is controlled by low- penetrance, common polymorphisms. Comparative genetics uses model organisms to study human disease. Rat strains exhibit different susceptibility phenotypes to chemical induced carcinogenesis. The Wistar-Furth (WF) rat strain is susceptible to chemically induced mammary carcinogenesis, while the Wistar-Kyoto (WKy) and Copenhagen (COP) rat strains are …

Classification System Of The Physical Streambed Habitat., Abolfazl Shafaie

Electronic Theses and Dissertations

A streambed is the channel bottom of a stream, river, or creek; the physical confine of the normal water flow. It provides necessities for fish and microinvertebrate including shelter, food, and breeding spots. Therefore, it is an essential part of aquatic animal habitats and often seen as an index of stream health. There is no generally accepted method to quantify streambed physical components and depending upon state and organization a variety of methods are used. The procedure provided in the rapid bioassessment protocol (RBP) (Kaufmann et al., 1999; Sylte and Fischenich, 2002) is probably the most widely used method to …

At The [Other Side Of The] Lectern, Emily Grant

Journal of Legal Education

No abstract provided.

Verification And Analysis Of Impact-Based Tornado Warnings In The Central Region Of The National Weather Service, Holly B. Obermeier

Department of Earth and Atmospheric Sciences: Dissertations, Theses, and Student Research

Tornado warnings are one of the most critical products issued by the National Weather Service (NWS), and favorable verification statistics are desirable. The 2011 NWS statistics for traditional tornado warnings indicate that the probability of detection (POD) is 70%, while the false alarm rate (FAR) is 76%. The recent Joplin, Missouri EF5 tornado event on 22 May 2011, which resulted in massive devastation and loss of life, prompted the NWS to re-evaluate the current tornado warning format. After the Joplin, MO event, the Central Region of the NWS implemented the impact-based tornado warning (IBTW) experiment in 2013. IBTWs consist of …

Rna Interference As A Tool For The Functional Analysis Of Genes In The Colorado Potato Beetle, Leptinotarsa Decemlineata (Say), Ashley Danielle Yates

Department of Entomology: Dissertations, Theses, and Student Research

RNA interference (RNAi) is a naturally occurring phenomenon in eukaryotes in which a double-stranded RNA (dsRNA) suppresses the expression of a target gene. RNAi has markedly changed the way in which functional genetics studies are performed, especially in non-model organisms. In insects, the efficacy of RNAi is influenced by several factors, including the species and the methods of dsRNAs delivery.

The Colorado potato beetle (CPB), Leptinotarsa decemlineata (Say), is a pest of the plant family Solanaceae. RNAi in the CPB is of interest for potential use in insect management and as a tool to study the interaction with host plants. …

A Case Study Of Changing Cropping Diversity And Agricultural Risk In The Doulthabad Mandal Of Telangana State In India, Srikanth Kondabolu

School of Natural Resources: Dissertations, Theses, and Student Research

The Doulthabad^[1] Mandal is a hot semi-arid agro-ecological sub-region (Rao et al. 2006) located in Mahbubnagar District on the North Telangana Plateau in the state of Telangana. Agriculture is the main occupation in this region, which is populated mostly with small and marginal farmers. This study uses the time period from 1971 to 2004 to study the variation in cropping pattern diversity and distribution of rainfall during the monsoons and understand the implications on production risk in agriculture. Quantitative methods were used in determining the changes in rainfall while qualitative methods were used to study cropping system changes. The …

Evaluation Of Pre-Harvest Screening For Antibiotics And Flunixin Meglumine In Cattle, Shuna A. Jones

School of Veterinary and Biomedical Sciences: Dissertations, Theses, and Student Research

Many antibiotics and medications used in the treatment of animals have a withdrawal time; residues are a concern for the meat industry. The most recently published 2009 USDA-FSIS Residue Program Data Report listed 135,389 Inspector-in-Charge-Generated (IICG) residue samples from 43,142,500 beef and dairy cattle inspected that year at harvest. Of these samples, 1,306 contained violative antibiotic residues and 327 violative flunixin meglumine residues. Two classes of antimicrobials comprised over half of the documented violative antimicrobial residues (beta-lactams that include ceftiofur and sulfa drugs that include sulfadimethoxine). While the violative residue rate seems small, violative residues are unacceptable. Management of carcasses …

Induced Hypothermia And Its Effects On Cardiac Arrhythmias, Shatoyia Barlow

HIM 1990-2015

The purpose of this integrated review of the literature was to determine the relationship between therapeutic hypothermia and cardiac arrhythmias. The reviewed literatures were English based articles from year 2003-2013. Relevant information from the American Heart Association and the International Liaison Committee on Resuscitation was used to further enhance research results. The results of this literature review showed hypothermia treatment propensity to prolong QT interval without precipitating life-threatening arrhythmias. Although arrhythmias can be potentially increased under induced hypothermia, it has been shown that treatment is easier while under hypothermic conditions. The reviewed research also shows that hypothermia treatment should be …

Animal-Like And Depraved: Racist Stereotypes, Commercial Sex, And Black Women's Identity In New Orleans, 1825-1917, Porsha Dossie

HIM 1990-2015

My objective with this thesis is to understand how racist stereotypes and myths compounded the sale of fair-skinned black women during and after the slave trade in New Orleans, Louisiana. This commodification of black women's bodies continued well into the twentieth century, notably in New Orleans' vice district of Storyville. Called "quadroons" (a person with ¼ African ancestry) and "octoroons" (1/8 African ancestry), these women were known for their "sexual prowess" and drew in a large number of patrons. The existence of "white passing" black women complicated ideas about race and racial purity in the South. Race as a myth …

What Is The Efficacy Of Peer Presentation For English Languag Learners?, Courtney Roy

HIM 1990-2015

This study investigates whether the learning strategy of Peer Presentations may positively influence an English Language Learner’s (ELL's) relationship with peers, and personal perspec-tives with pertinence to the sciences, public discourse, and their institution. Data collection in-struments included a developed pre- and post-sociometric survey to quantitate each classroom's social status, and a pre- and post-qualitative oral interview to acquire individual perceptions con-cerning enjoyment and contentment of academic topics. Three ELLs from two learning environ-ments participated with the eight day intervention, comprising of 45 minute instructive sessions to become proficient with demonstrating an arrangement of invigorating yet harmless scientific experiments. After …

Determining The Minimum Number Of Individuals And Significance Of The Kuelap Ossuary In Chachapoyas, Peru, Vu Tran

HIM 1990-2015

The pre-Hispanic archaeological site of Kuelap in Chachapoyas, Peru, is representative of the variation in mortuary practices observed throughout the Chachapoya region. The goal of this study was to analyze the human skeletal remains excavated in the center of the Circular Platform between residential structures at Kuelap by creating an inventory of the remains (n=2,573) and determine the minimum number of individuals originally interred in the mortuary context. This study observed a total of 171 femora, 159 humeri, 74 calcanei, 110 ilium bones, 86 temporal bones, and 74 maxillae. Results show that this mortuary context was an ossuary of secondarily, …

The Banner - V. 149, No. 8 - (August 2014), Christian Reformed Church In North America

The Banner

No abstract provided.

Number And Size Of Paddocks In A Grazing System, Edward Barrow Rayburn

Faculty & Staff Scholarship

WVU-Extension fact sheet

Principles Of Grazing Management, Edward Barrow Rayburn

Faculty & Staff Scholarship

WVU-Extension fact sheet

The Mechanism Of Self-Organized Beating Of Cilia, Jyothish Vidyadharan

Dissertations - ALL

No abstract provided.

08 Fourier Analysis, Charles G. Torre

Foundations of Wave Phenomena

We now would like to show that one can build up the general solution of the wave equation by superimposing certain elementary solutions. Indeed, the elementary solutions being referred to are those discussed in §6. These elementary solutions will form a very convenient “basis” for the vector space of solutions to the wave equation, just as the normal modes provided a basis for the space of solutions in the case of coupled oscillators. Indeed, as we shall see, the elementary solutions are the normal modes for wave propagation. The principal tools needed to understand this are provided by the methods …

Problem Set 6, Charles G. Torre

Foundations of Wave Phenomena

Problem Set 6

13 Spherical Coordinates, Charles G. Torre

Foundations of Wave Phenomena

The spherical coordinates of a point p can be obtained by the following geometric construction. The value of r represents the distance from the point p to the origin (which you can put wherever you like). The value of ✓ is the angle between the positive z-axis and a line l drawn from the origin to p. The value of " is the angle made with the x-axis by the projection of l into the x-y plane (z = 0). Note: for points in the x-y plane, r and " (not ✓) are polar coordinates. The coordinates (r, ✓, ") …

Problem Set 4, Charles G. Torre

Foundations of Wave Phenomena

Problem Set 4

Cardiac, Skeletal, And Smooth Muscle Mitochondrial Respiration: Are All Mitochondria Created Equal?, Song-Young Park, J. R. Gifford, R. H. I. Andtbacka, Joel D. Trinity, John R. Hyngstrom, Ryan S. Garten, Nikolaos A. Diakos, S. J. Ives, Flemming Dela, Steen Larsen, Stavros Drakos, Russell S. Richardson

Health and Kinesiology Faculty Publications

Unlike cardiac and skeletal muscle, little is known about vascular smooth muscle mitochondrial respiration. Therefore, the present study examined mitochondrial respiratory rates in smooth muscle of healthy human feed arteries and compared with that of healthy cardiac and skeletal muscles. Cardiac, skeletal, and smooth muscles were harvested from a total of 22 subjects (53 ± 6 yr), and mitochondrial respiration was assessed in permeabilized fibers. Complex I + II, state 3 respiration, an index of oxidative phosphorylation capacity, fell progressively from cardiac to skeletal to smooth muscles (54 ± 1, 39 ± 4, and 15 ± 1 pmol·s−1·mg−1, P < 0.05, respectively). Citrate synthase (CS) activity, an index of mitochondrial density, also fell progressively from cardiac to skeletal to smooth muscles (222 ± 13, 115 ± 2, and 48 ± 2 μmol·g−1·min−1, P …