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2014

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Articles 4681 - 4710 of 20688

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Cyclic Di-Gmp-Dependent Signaling Pathways In The Pathogenic Firmicute Listeria Monocytogenes, Li-Hong Chen, Volkan K. Köseoğlu, Zehra T. Güvener, Tanya Myers-Morales, Joseph M. Reed, Sarah E. F. D'Orazio, Kurt W. Miller, Mark Gomelsky Aug 2014

Cyclic Di-Gmp-Dependent Signaling Pathways In The Pathogenic Firmicute Listeria Monocytogenes, Li-Hong Chen, Volkan K. Köseoğlu, Zehra T. Güvener, Tanya Myers-Morales, Joseph M. Reed, Sarah E. F. D'Orazio, Kurt W. Miller, Mark Gomelsky

Microbiology, Immunology, and Molecular Genetics Faculty Publications

We characterized key components and major targets of the c-di-GMP signaling pathways in the foodborne pathogen Listeria monocytogenes, identified a new c-di-GMP-inducible exopolysaccharide responsible for motility inhibition, cell aggregation, and enhanced tolerance to disinfectants and desiccation, and provided first insights into the role of c-di-GMP signaling in listerial virulence. Genome-wide genetic and biochemical analyses of c-di-GMP signaling pathways revealed that L. monocytogenes has three GGDEF domain proteins, DgcA (Lmo1911), DgcB (Lmo1912) and DgcC (Lmo2174), that possess diguanylate cyclase activity, and three EAL domain proteins, PdeB (Lmo0131), PdeC (Lmo1914) and PdeD (Lmo0111), that possess c-di-GMP phosphodiesterase activity. Deletion of all …

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Efficacy Of Optical Coherence Tomography In The Detection Of Potentially Malignant Oral Mucosal Lesions Of The Tongue: An Animal Model, Hugo Cesar Campos Jaramillo Aug 2014

Efficacy Of Optical Coherence Tomography In The Detection Of Potentially Malignant Oral Mucosal Lesions Of The Tongue: An Animal Model, Hugo Cesar Campos Jaramillo

Master's Theses

No abstract provided.

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Biological Implications Of Satellite Cells For Scaffold-Based Muscle Regenerative Engineering, Maggie R. Del Ponte, Charter Chain, Meng Deng Dr., Feng Yue Dr., Shihuan Kuang Dr. Aug 2014

Biological Implications Of Satellite Cells For Scaffold-Based Muscle Regenerative Engineering, Maggie R. Del Ponte, Charter Chain, Meng Deng Dr., Feng Yue Dr., Shihuan Kuang Dr.

The Summer Undergraduate Research Fellowship (SURF) Symposium

Satellite cells are anatomically localized along the surface of muscle fibers and have been regarded as a population of muscle-specific progenitors that are responsible for muscle regeneration. In response to muscle injuries, satellite cells are activated to enter the cell cycle, then proliferate and differentiate into mature muscle cells to regenerate damaged myofibers. Unfortunately, this natural repair mechanism is interrupted in conditions such as muscle degenerative diseases or volumetric muscle loss. The function of stem cells is regulated by signals from their local microenvironment which is called the stem cell niche. Current satellite cell-based strategies such as direct cell transplantation …

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Interaction Between Insecticide Exposure And Trematode Infection Across Four Wood Frog Populations, Michael J. Hiatt, Jessica Hua Dr., Vanessa Wuerthner, Jason Hoverman Dr. Aug 2014

Interaction Between Insecticide Exposure And Trematode Infection Across Four Wood Frog Populations, Michael J. Hiatt, Jessica Hua Dr., Vanessa Wuerthner, Jason Hoverman Dr.

The Summer Undergraduate Research Fellowship (SURF) Symposium

Amphibian populations are declining worldwide due to a number of stressors including pesticides and parasites. Conservation of these animals can be complicated because populations can differ dramatically in response to the same stressor. When consistently exposed to pesticides, some populations evolve tolerance through the process of natural selection acting across multiple generations. Alternatively, populations that are intermittently exposed to pesticides induce tolerance within a single generation. To date, however, there have been few studies examining the costs associated with these different stress tolerance mechanisms. In this study, we examined how difference in stress tolerance influence susceptibility to parasitic infections. We …

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Molecular Exploration Tool, Weiyi Cao, Nicolas Onofrio, Alejandro Strachan Aug 2014

Molecular Exploration Tool, Weiyi Cao, Nicolas Onofrio, Alejandro Strachan

The Summer Undergraduate Research Fellowship (SURF) Symposium

Density Functional Theory (DFT) which is based on quantum mechanics theory has been broadly used to compute the energy and the structure of molecules and solids. However, the DFT method is limited when running calculations for a large system and only thousands of atoms can be solved. Alternatively, Molecular Dynamics (MD) simulation can be used to investigate the properties of the atomic system for large systems in the classical mechanics approximation. When running the MD simulation, the electronic structure is approximated by Force Fields (FF) which can be parametrized against DFT calculations. Nevertheless, the accuracy of the MD results and …

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Medical Applications Of Mrc, Kyle Thackston, Henry Mei, Pedro Irazoqui Aug 2014

Medical Applications Of Mrc, Kyle Thackston, Henry Mei, Pedro Irazoqui

The Summer Undergraduate Research Fellowship (SURF) Symposium

Consistent powering is a limiting reagent for many medical implants and sensors. Powering in-vivo devices in animal studies requires either transcutaneous wiring (limiting mobility and increasing the chance of infection) or an implanted battery (limited lifetime and limits size of device). Wireless power transfer (WPT) would be able to overcome these challenges and permit the use of more advanced implantable devices in a research setting. Magnetic resonance coupling (MRC), an advanced form of inductive charging, allows good transfer efficiencies over significant air gaps, but works best a specific location and frequency, limiting mobility in animal studies. Using band-pass filter theory, …

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Tumor-Microenvironment-On-Chip To Mimic Tumor Heterogeneity, Victoria Noe-Kim, Altug Ozcelikkale, Bumsoo Han Aug 2014

Tumor-Microenvironment-On-Chip To Mimic Tumor Heterogeneity, Victoria Noe-Kim, Altug Ozcelikkale, Bumsoo Han

The Summer Undergraduate Research Fellowship (SURF) Symposium

Ductal Carcinoma In Situ (DCIS) is a non-invasive cancer that forms around breast milk ducts that can potentially progress into invasive breast cancer if untreated. Lack of models to study its diverse pathophysiology and differential response to treatments poses a challenge to develop standard treatment modalities with improved therapeutic outcomes. The traditional in vitro models such as cell monolayer are convenient but insufficient to represent the physiological characteristics of DCIS tumor microenvironment and often fail to predict clinical outcomes. The animal models effectively simulate the in vivo environment but also lack the ability to control the environmental parameters to match …

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Seedling Uptake And Fate Of Soil-Applied Capsaicin, A Potential Browse Deterrent, Carmen K. Dobbs, Joshua L Sloan, Douglass F. Jacobs Aug 2014

Seedling Uptake And Fate Of Soil-Applied Capsaicin, A Potential Browse Deterrent, Carmen K. Dobbs, Joshua L Sloan, Douglass F. Jacobs

The Summer Undergraduate Research Fellowship (SURF) Symposium

Seedling damage due to browse constitutes a major challenge to afforestation and reforestation efforts in the Central Hardwood Forest region of the USA. Many efforts have been made to deter herbivores, but the costs, implementation methods, and relative ineffectiveness of existing mitigation options often preclude operational implementation. An alternate means of deterring wildlife browse is capsaicin, a hot pepper concentrate, which has been reported to decrease herbivory of tree seedlings and is available in a controlled-release form designed to act systemically following application to the soil and subsequent plant uptake. However, the degree to which seedlings are capable of absorbing …

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Quantification Of Lps Eluate From Coated Microelectrode Devices, Jahrane A. Dale, Janak Gaire, Kevin J. Otto Aug 2014

Quantification Of Lps Eluate From Coated Microelectrode Devices, Jahrane A. Dale, Janak Gaire, Kevin J. Otto

The Summer Undergraduate Research Fellowship (SURF) Symposium

Penetrating microelectrode arrays have a great potential to be used as control and communication interfaces for neuroprosthetics. A persistent obstacle in the clinical implementation of microelectrode arrays is the chronic degradation of these devices, putatively due to the foreign body response. Though researchers have studied the progression of the foreign body response and the effect of anti-inflammatory drugs on the efficacy of the implant, the exact biological mechanisms of implant degradation are not fully understood. To more closely investigate the effect of the foreign body response on device degradation, neuroinflammation can be exacerbated by coating dummy electrodes implanted into mice …

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Chronic Brain Stimulation Using Micro-Ecog Devices, Hayden C. Carney, Roy Lycke, Kevin J. Otto, Amelia A. Schendel, Justin Williams Aug 2014

Chronic Brain Stimulation Using Micro-Ecog Devices, Hayden C. Carney, Roy Lycke, Kevin J. Otto, Amelia A. Schendel, Justin Williams

The Summer Undergraduate Research Fellowship (SURF) Symposium

Recording and stimulating brain activity has had great success both as a research tool and as a clinical technique. Neural prosthetics can replace limbs, restore hearing, and treat disorders like Parkinson’s and epilepsy, but are relatively crude. Current neural prosthetic systems use penetrating electrodes to achieve high precision, but the invasive nature of these devices provoke a strong immune response that limits chronic use. (Polikov et al) In our study we evaluate micro-electrocortiographic (micro-ECoG) devices which sit under the skull and on the surface of the brain for stimulation over chronic timescales. We anticipate these devices with their less invasive …

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New Insight Into The Effects Of Small Heat Shock Proteins On Callipyge Lamb Meat Tenderness, Traci Cramer, Yuan H Brad Kim, Danyi Ma, Jolena N. Waddell, Moriah Penick Aug 2014

New Insight Into The Effects Of Small Heat Shock Proteins On Callipyge Lamb Meat Tenderness, Traci Cramer, Yuan H Brad Kim, Danyi Ma, Jolena N. Waddell, Moriah Penick

The Summer Undergraduate Research Fellowship (SURF) Symposium

Callipyge lambs are a type of sheep that are genetically known to produce tough meat. High expression of calpastatin, which inhibits proteolytic activity of µ-calpain, has been identified as the main factor behind the toughness of callipyge lamb meat. Another group of proteins called small heat shock proteins (sHSP) has recently been suggested for its possible involvement in tenderness development of meat, where up-regulation of sHSP may be associated with toughness. However, the role of sHSP in meat tenderization of callipyge lambs has never been investigated; therefore, the objective of this study is to determine possible involvement of sHSP in …

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Evaluating Contaminants Of Emerging Concern In Commercial Biosolid-Based Fertilizers, John Hemmerling, Michael L. Mashtare, Linda S. Lee Aug 2014

Evaluating Contaminants Of Emerging Concern In Commercial Biosolid-Based Fertilizers, John Hemmerling, Michael L. Mashtare, Linda S. Lee

The Summer Undergraduate Research Fellowship (SURF) Symposium

The production and popularity of commercially available biosolid-based fertilizers are increasing because of their economic, environmental, and plant nutrition benefits, particularly in urban and suburban areas. Because biosolid-based fertilizers are derived from waste water treatment plant residuals, we hypothesized that there is the potential for micropollutants to persist in these products. Their presence would be of particular concern due to their potential impact on human and ecological health and risk of bioaccumulation. This study involves quantifying contaminants of emerging concern in three biosolid-based fertilizers, and 2 non-biosolid-based fertilizers, a composted animal manure and an organic compost. Our extraction method employed …

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Design And Fabrication Of A Novel Electrospinning System For Musculoskeletal Tissue Regeneration, Carter L. Chain, Maggie R. Del Ponte, Meng Deng, Feng Yue, Shihuan Kuang Aug 2014

Design And Fabrication Of A Novel Electrospinning System For Musculoskeletal Tissue Regeneration, Carter L. Chain, Maggie R. Del Ponte, Meng Deng, Feng Yue, Shihuan Kuang

The Summer Undergraduate Research Fellowship (SURF) Symposium

Disease and injury to human tissue, especially musculoskeletal tissue, is a prevalent concern to the public, affecting millions of people each year. Current treatment options involving autografts and allografts are hindered by limited availability and risk of immunogenicity, respectively. In order to overcome these limitations, a transdisiplinary regenerative engineering strategy has emerged with a focus on the development of biomimetic scaffolds that closely mimic the properties of the native tissues. For example, the structure of muscle tissue is characterized by oriented muscle fibers. However, fabrication of aligned nanofiber structures that mimic the anisotropic organization of muscle presents significant engineering challenges. …

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Summary Of Brown V. Mcdaniel. 130 Nev. Adv. Op. 60, Allison Vitangeli Aug 2014

Summary Of Brown V. Mcdaniel. 130 Nev. Adv. Op. 60, Allison Vitangeli

Nevada Supreme Court Summaries

The Court determined whether the ineffective assistance of post-conviction counsel may constitute good cause under NRS 34.726(1) and NRS 34.810 to allow a noncapital petitioner to file an untimely and successive post-conviction petition for a writ of habeas corpus.

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Appropriate Development Of The Liver Treg Compartment Is Modulated By The Microbiota And Requires Tgf-Β And Myd88, Ann Maria, Kathryn A. English, James D. Gorham Aug 2014

Appropriate Development Of The Liver Treg Compartment Is Modulated By The Microbiota And Requires Tgf-Β And Myd88, Ann Maria, Kathryn A. English, James D. Gorham

Dartmouth Scholarship

Neither the early postnatal development of the liver Treg compartment nor the factors that regulate its development has been characterized. We compared the early developmental patterns of Treg cell accumulation in murine liver, thymus, and spleen. A FoxP3EGFP reporter mouse was employed to identify Treg cells. Mononuclear cells were isolated from organs postnatally, stained for CD4, and examined by flow cytometry to enumerate FoxP3+CD4hi cells. To assess roles for TGF-��1, MyD88, and TLR2, gene specific knockout pups were generated from heterozygous breeders. To test the role of commensal bacteria, pregnant dams were administered antibiotics during gestation and after parturition.The pattern …

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Cubesat Advanced Technology Propulsion System Concept, Dennis Morris, Rodney Noble Aug 2014

Cubesat Advanced Technology Propulsion System Concept, Dennis Morris, Rodney Noble

Small Satellite Conference

One of the many challenges when it comes to small satellites is low cost, especially when it comes to propulsion. At Aerojet Rocketdyne a CubeSat propulsion system was developed utilizing the advantages of the additive manufacturing process. This design reduces the part count by 50%, eliminates all 22 final assembly welds and reduces the projected recurring propulsion system cost by 75%. Starting with the CubeSat envelope of 1000 cubic centimeters, a typical satellite hydrazine mono propellant propulsion system was created for a baseline comparison. The goal of the advanced technology low cost propulsion system was to minimize part count by …

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Reining In The Use Of Performance Enhancing Drugs In Horseracing: Why A Federal Regulation Is Needed, Kyle Cassidy Aug 2014

Reining In The Use Of Performance Enhancing Drugs In Horseracing: Why A Federal Regulation Is Needed, Kyle Cassidy

Seton Hall Journal of Sports and Entertainment Law

No abstract provided.

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An Autonomous Proximity Navigation Testbed For Nanosatellites, Subhransu Mishra, Marin Kobilarov Aug 2014

An Autonomous Proximity Navigation Testbed For Nanosatellites, Subhransu Mishra, Marin Kobilarov

Small Satellite Conference

The goal of this work is to develop techniques and tools to enhance small-spacecraft in-orbit autonomy. The focus is on developing perception and control algorithms to enable autonomous proximity operations, and performing preliminary validation in a laboratory air-bearing testbed. To achieve this, we have developed CubeSat engineering models equipped with a simple cold-gas propulsion system, on-board vision-based sensing and embedded computer for perception and control algorithms, and integrated them in the air-bearing testbed. Basic point-to-point autonomous navigation and obstacle avoidance tasks on such a planar environment have been successfully demonstrated.

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Integrating Content And Academic Language Using Balanced Literacy Structures: A Framework For Instruction Of Emergent Bilinguals, Patricia Velasco Aug 2014

Integrating Content And Academic Language Using Balanced Literacy Structures: A Framework For Instruction Of Emergent Bilinguals, Patricia Velasco

Journal of Multilingual Education Research

Teachers working with emergent bilinguals1 face difficult dilemmas. Students who do not receive rigorous content instruction fail to acquire academic language. However, if students do not understand the content or cannot participate in content lessons, they cannot be expected to learn the academic information and the language associated with it. Confronting this challenge requires a sound knowledge of the multiple factors that play a role in developing academic language and its dependency on content area texts. Most importantly, this understanding has to be accompanied by instructional strategies that allow students to gain steady control over academic discourse. In this article, …

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2014 August 6 -- Agenda And Attachments Aug 2014

2014 August 6 -- Agenda And Attachments

Agendas and Minutes

No abstract provided.

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Propsectus, August 6, 2014, Kaleb Schwaiger Aug 2014

Propsectus, August 6, 2014, Kaleb Schwaiger

Prospectus 2014

EBOLA VIRUS UNLIKELY TO SPREAD IN U.S.; City or tropics? Obama ponders where to put presidential library; Twin sisters turn mere mortals into mermaids; Tips to get ready for the new school year; EPA's limits can be met; Understanding the difference: curriculum and standards; Winona State football player passes away during practice; 'Guardians of the Galaxy' rockets to $94 million opening; Twenty years later, NIN and Soundgarden still rock

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What Enables Size-Selective Trophy Hunting Of Wildlife?, Chris T. Darimont, K. Rosie Child Aug 2014

What Enables Size-Selective Trophy Hunting Of Wildlife?, Chris T. Darimont, K. Rosie Child

Big-Game and Trophy Hunting Collection

Although rarely considered predators, wildlife hunters can function as important ecological and evolutionary agents. In part, their influence relates to targeting of large reproductive adults within prey populations. Despite known impacts of sizeselective harvests, however, we know little about what enables hunters to kill these older, rarer, and presumably more wary individuals. In other mammalian predators, predatory performance varies with knowledge and physical condition, which accumulates and declines, respectively, with age. Moreover, some species evolved camouflage as a physical trait to aid in predatory performance. In this work, we tested whether knowledge-based faculty (use of a hunting guide with accumulated …

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Volume 51, Number 51: August 06, 2014, University Of North Dakota Aug 2014

Volume 51, Number 51: August 06, 2014, University Of North Dakota

University Letter Archive

No abstract provided.

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Rural Wind Windfalls, K.K. Duvivier Aug 2014

Rural Wind Windfalls, K.K. Duvivier

Sturm College of Law: Faculty Scholarship

Wind power can provide rural communities with unexpected gains or “windfalls.” As one North Dakota farmer put it, “Who could have guessed that the air above our land might be worth money someday?” According to the National Renewable Energy Laboratory (NREL), the amount of installed wind electricity capacity in the United States increased by a factor of 25 between 2000 and 2012. The United States is second, behind only China, for the most wind electricity capacity in the world. In 2012, Kansas more than doubled its installed wind capacity by adding 1,441 MW to the 1,272 MW installed before that …

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The Murray Ledger And Times, August 6, 2014, The Murray Ledger And Times Aug 2014

The Murray Ledger And Times, August 6, 2014, The Murray Ledger And Times

The Murray Ledger & Times

No abstract provided.

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Travel As A Ritual Toward Transformative Consciousness: Juxtaposing Che Guevara’S Biography And Teacher Candidates’ Narratives, Yishan Lea Aug 2014

Travel As A Ritual Toward Transformative Consciousness: Juxtaposing Che Guevara’S Biography And Teacher Candidates’ Narratives, Yishan Lea

All Faculty Scholarship for the College of Education and Professional Studies

This article discusses the development of critical consciousness by examining
the biographical-narratives in relationship to the experiential accounts on
travel. Biographical narratives are important cultural texts filled with history
and cultural nuances. The biography of Ernesto Che Guevara has resonated
with readers and viewers from around the world. By dreaming seemingly
impossible dreams and garnering triumph in the face of mounting obstacles,
Che has inspired the generations that have followed him. The life of Che,
which is a myth of idealism, has captivated the hearts of many around the
globe. This paper engages in the process of reading student narratives …

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The Geomagnetic Environment In Which Sea Turtle Eggs Incubate Affects Subsequent Magnetic Navigation Behaviour Of Hatchlings, Matthew J. Fuxjager, Kyla R. Davidoff, Lisa A. Mangiamele, Kenneth J. Lohmann Aug 2014

The Geomagnetic Environment In Which Sea Turtle Eggs Incubate Affects Subsequent Magnetic Navigation Behaviour Of Hatchlings, Matthew J. Fuxjager, Kyla R. Davidoff, Lisa A. Mangiamele, Kenneth J. Lohmann

Biological Sciences: Faculty Publications

Loggerhead sea turtle hatchlings (Caretta caretta) use regional magnetic fields as open-ocean navigational markers during trans-oceanic migrations. Little is known, however, about the ontogeny of this behaviour. As a first step towards investigating whether the magnetic environment in which hatchlings develop affects subsequent magnetic orientation behaviour, eggs deposited by nesting female loggerheads were permitted to develop in situ either in the natural ambient magnetic field or in a magnetic field distorted by magnets placed around the nest. In orientation experiments, hatchlings that developed in the normal ambient field oriented approximately south when exposed to a field that exists near the …

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Out Of Africa, Bridget Finnegan Aug 2014

Out Of Africa, Bridget Finnegan

UNH Today Archive

No abstract provided.

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An Analysis Of Vegetation Recovery Following Dam Removal At Hemlock Recreation Site, Washington, Greer Stewart Ramsey Aug 2014

An Analysis Of Vegetation Recovery Following Dam Removal At Hemlock Recreation Site, Washington, Greer Stewart Ramsey

Dissertations and Theses

Dam removals are becoming increasingly common as dams reach their life expectancy and face costly upgrades associated with relicensing. Though removal is often viewed as a success in terms of ecological restoration, it also represents a major disturbance to an area. Previous research has shown that native species do not survive as well at these disturbed sites, and invasive species often dominate. This study examines the vegetation response in the drained reservoir area after the removal of Hemlock Dam on Trout Creek, a tributary to the Wind River in southern Washington. Transects were established and quadrats were sampled to determine …

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Imaging Luciferase-Expressing Viruses, Michael A. Barry, Shannon May, Eric A. Weaver Aug 2014

Imaging Luciferase-Expressing Viruses, Michael A. Barry, Shannon May, Eric A. Weaver

Nebraska Center for Virology: Faculty Publications

Optical imaging of luciferage gene expression has become a powerful tool to track cells and viruses in vivo in small animal models. Luciferase imaging has been used to study the location of infection by replication-defective and replication-competent viruses and to track changes in the distribution of viruses in mouse models. This approach has also been used in oncolytic studies as a non-invasive means to monitor the growth and killing of tumor cells modified with luciferase genes. In this chapter, we describe the techniques used for luciferase imaging as have been applied to track replication-defective and replication-competent adenoviruses in mouse and …

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