Digital Commons Network^™

Globalization And The Exchange Of Aesthetics, Ajay Kapadia

Journal of Undergraduate Research at Minnesota State University, Mankato

Not only has globalization been growing over the last few years, but the anti-globalization movement has been growing as well. Anti-globalists predict that the globalization is responsible for negatively altering people's mindset, outlook and lifestyle. However, the anti-globalization movement has been negligent in considering the full effects of globalization. In its simplest sense globalization can be defined as: “the worldwide movement toward economic, financial, trade, and communications integration". The parameters of communications integration can be defined as “all means of symbolic or verbal communication that people and machines use to make contact and share information”. This paper will investigate the …

The Abundance And Diversity Of Intestinal Trematodes Collected From Blue Winged Teal And Ring-Neck Ducks Inhabiting Lake Winnibigoshish, Minnesota, Omolayo Ogunnowo

Journal of Undergraduate Research at Minnesota State University, Mankato

This study investigated the abundance and diversity of parasites residing in the digestive tracts of blue winged teal and ring-necked ducks collected at Lake Winnibigoshish, MN. The trematode parasites we focused on in this study were removed from the anterior-most, 15cm segment of the small intestine of 10 individuals of each bird species. The parasites were initially stored in 10% formalin and were subsequently stained with Schneider’s aceto carmine, then mounted on microscope slides for diagnostic purposes. A total of 1605 trematodes were recovered from the birds. We found that blue wing teal and ring-necked ducks tended to contain different …

Instrumental Variable Estimation In A Survival Context, Eric J. Tchetgen Tchetgen, Stefan Walter, Stijn Vansteelandt, Torben Martinussen, Maria Glymour

Harvard University Biostatistics Working Paper Series

No abstract provided.

Cryopreservation Of Hepatocyte (Hepg2) Cell Monolayers: Impact Of Trehalose, Blake Stokich, Quinn Osgood, David Grimm, Shhyam Moorthy, Nilay Chakraborty, Michael A. Menze

Faculty Research & Creative Activity

A simple method to cryogenically preserve hepatocyte monolayers is currently not available but such a technique would facilitate numerous applications in the field of biomedical engineering, cell line development, and drug screening. We investigated the effect of trehalose and dimethyl sulfoxide (Me2SO) in cryopreservation of human hepatocellular carcinoma (HepG2) cells in suspension and monolayer formats. HepG2 cell monolayers were incubated for 24 h at varying concentrations of trehalose (50–150 mM) prior to cryopreservation to identify the optimum concentration for such preincubation. When trehalose alone was used as the cryoprotective agent (CPA), cells in monolayer format did not survive freezing while …

Kcnj10 Determines The Expression Of The Apical Na-Cl Cotransporter (Ncc) In The Early Distal Convoluted Tubule (Dct1), Chengbiao Zhang, Lijun Wang, Junhui Zhang, Xiao-Tong Su, Dao-Hong Lin, Ute I. Scholl, Gerhard Giebisch, Richard P. Lifton, Wen-Hui Wang

NYMC Faculty Publications

The renal phenotype induced by loss-of-function mutations of inwardly rectifying potassium channel (Kir), Kcnj10 (Kir4.1), includes salt wasting, hypomagnesemia, metabolic alkalosis and hypokalemia. However, the mechanism by which Kir.4.1 mutations cause the tubulopathy is not completely understood. Here we demonstrate that Kcnj10 is a main contributor to the basolateral K conductance in the early distal convoluted tubule (DCT1) and determines the expression of the apical Na-Cl cotransporter (NCC) in the DCT. Immunostaining demonstrated Kcnj10 and Kcnj16 were expressed in the basolateral membrane of DCT, and patch-clamp studies detected a 40-pS K channel in the basolateral membrane of the DCT1 of …

Flavonoid Treatment Of Glycogen Synthase Kinase-Based Disease, Jun Tan, Doug Shytle, Kavon Rezai-Zadeh

USF Patents

The flavonoid luteolin reduces amyloid-β peptide (Aβ) generation. Luteolin is also a selective GSK-3 inhibitor that 1) decreases amyloidogenic γ-secretase APP processing, and 2) promotes presenilin 1 (PS1) carboxyl-terminal fragment (CTF) phosphorylation. GSK-3α activity is essential for both PS1 CTF phosphorylation states and PS1-APP interaction. These findings were validated in vivo, using a Tg2576 Alzheimer's Disease model system. Luteolin treatment decreased soluble Aβ levels, reduced GSK-3 activity, and disrupted PS1-APP association. In addition, Tg2576 mice treated with diosmin, a glycoside of a flavone structurally and functionally similar to luteolin (diosmetin), displayed significantly reduced Aβ pathology as well.

Method For The Treatment Of Malignancies, Richard Heller, Loree C. Heller

USF Patents

A method of treating cancerous tumors is presented herein. The method includes injecting an effective dose of a plasmid encoded for IL-12, B7-1 or IL-15 into a cancerous tumor and subsequently administering at least one high voltage, short duration pulse to the tumor. The electroporation pulses may be administered at least 700V/cm for a duration of less than 1 millisecond. The intratumor treatments with electroporation may be administered in at least a two-treatment protocol with the time between treatments being about 7 days. The intratumor treatments with electroporation may be administered in a three-treatment protocol with a time of four …

Placental Fkbp5 Genetic And Epigenetic Variation Is Associated With Infant Neurobehavioral Outcomes In The Richs Cohort, Alison G. Paquette, Barry M. Lester, Devin C. Koestler, Corina Lesseur, David A. Armstrong, Carmen J. Marsit

Dartmouth Scholarship

Adverse maternal environments can lead to increased fetal exposure to maternal cortisol, which can cause infant neurobehavioral deficits. The placenta regulates fetal cortisol exposure and response, and placental DNA methylation can influence this function. FK506 binding protein (FKBP5) is a negative regulator of cortisol response, FKBP5 methylation has been linked to brain morphology and mental disorder risk, and genetic variation of FKBP5 was associated with post-traumatic stress disorder in adults. We hypothesized that placental FKBP5 methylation and genetic variation contribute to gene expression control, and are associated with infant neurodevelopmental outcomes assessed using the Neonatal Intensive Care Unit (NICU) Network …

Methods And Compositions For Inhibiting The Proliferation Of Cancer Cells (Div), Ratna Chakrabarti

UCF Patents

A method of decreasing the expression of LIM kinase 1 in a cancer cell comprising; providing an oligonucleotide consisting of the sequence of SEQ ID NO: 1; providing a cancer cell comprising an mRNA encoding LIM kinase 1; and introducing the oligonucleotide into the cancer cell, wherein the oligonucleotide decreases the expression of LIM kinase 1 in the cancer cell. The method also provides compositions of an antisense RNA LIM kinase 1 that can be administered to an individual for the purpose of inhibiting a protein kinase pathway and which further comprises methods for treating and monitoring the proliferation and …

Trophic Cascade Effects Of Deer Overabundance On Connecticut's Native Vegetation And Small Mammal Populations, Megan A. Floyd

Master's Theses

No abstract provided.

Conservation Of Bridle Shiner (Notropis Bifrenatus) In Connecticut: Issues In Detecting An Elusive Species, Kasey C. Pregler

Master's Theses

Bridle Shiner (Notropis bifrenatus) is apparently declining over most of its range and is currently listed as a species of concern in Connecticut. Using an occupancy modeling framework in program PRESENCE, my study compared seining and electrofishing backpack unit detection probabilities of Bridle Shiner. This research indicated the apparent decline of Bridle Shiner in the state was in part due to changes in sampling gear used for statewide surveys. Seining used 50 years ago was demonstrably more effective at capturing Bridle Shiner than the currently favored and more frequently used electrofishing gear. In light of this recent finding, …

Machine Learning Of Visual Object Categorization: An Application Of The Sustain Model, Gs Carmantini, A Cangelosi, Aj Wills

School of Psychology

Formal models of categorization are psychological theories that try to describe the process of categorization in a lawful way, using the language of mathematics. Their mathematical formulation makes it possible for the models to generate precise, quantitative predictions. SUSTAIN (Love, Medin & Gureckis, 2004) is a powerful formal model of categorization that has been used to model a range of human experimental data, describing the process of categorization in terms of an adaptive clustering principle. Love et al. (2004) suggested a possible application of the model in the field of object recognition and categorization. The present study explores this possibility, …

On The Absence Of Tp And Its Consequences: Evidence From Korean, Jungmin Kang

Doctoral Dissertations

This thesis explores the possibility that article-less languages may lack Tense Phrase (TP) projection (cf. Bošković 2012), focusing on Korean. I argue that Korean lacks TP and that the absence of TP in Korean results in a non-phasal Complementizer Phrase (CP) in Korean. I also provide an account of temporal interpretation in Korean that does not involve TP. In Chapter 2 I adopt Chomsky’s (2008) C-T association and Takahashi’s (2011) case-valuation approach to phase heads (a combination in which the lack of TP voids the phasehood of CP), and argue that CP/vP are not phases in Korean (although they are …

Cryopreservation Of Hepatocyte (Hepg2) Cell Monolayers: Impact Of Trehalose, Blake Stokich, Quinn Osgood, David Grimm, Shhyam Moorthy, Nilay Chakraborty, Michael Menze

Faculty and Staff Scholarship

A simple method to cryogenically preserve hepatocyte monolayers is currently not available but such a technique would facilitate numerous applications in the field of biomedical engineering, cell line development, and drug screening. We investigated the effect of trehalose and dimethyl sulfoxide (Me2SO) in cryopreservation of human hepatocellular carcinoma (HepG2) cells in suspension and monolayer formats. HepG2 cell monolayers were incubated for 24 h at varying concentrations of trehalose (50–150 mM) prior to cryopreservation to identify the optimum concentration for such preincubation. When trehalose alone was used as the cryoprotective agent (CPA), cells in monolayer format did not survive freezing while …

Pemanfaatan Asap Cair Kayu Putih (Malaleuca Cajuputi) Sebagai Antioksidan Dalam Pengolahan Ikan Tuna Asap, Daniel Ambrosius Nicolas Apituley, Jusuf Leiwakabessy, Esterlina Elizabeth Elsina Martha Loh

Chimica et Natura Acta

Asap cair mempunyai peluang untuk digunakan secara luas di Maluku karena ketersediaan bahan baku yang melimpah terutama bahan baku yang berasal dari limbah hasil pertanian maupun hasil pengolahan minyak kayu putih. Batang dan ranting kayu putih dapat digunakan sebagai bahan baku dalam pembuatan asap cair. Asap cair yang dibuat melalui pirolisis kayu putih tersebut mengandung komponen senyawa yang dapat berperan sebagai antioksidan yang dapat menghambat maupun mencegah terjadinya proses oksidasi. Penelitian ini bertujuan untuk mengkaji komponen kimia penyusun asap cair yang dapat berperan sebagai antioksidan serta kemampuannya dalam mencegah terjadinya kerusakan oksidatif pada ikan Tuna asap. Hasil analisis dengan GC-MS …

Alumnus, Zookeeper Celebrates World Elephant Day At Memphis Zoo, Winthrop University

Winthrop News 2014

• Today marks World Elephant Day, an international project that raises awareness of the urgent plight of Asian and African elephants.
• Thomas Reid '10, a zookeeper at Memphis Zoo, cares for the zoo's three African elephants.

Toward Image-Based Three-Dimensional Reconstruction From Cubesats: Impacts Of Spatial Resolution And Snr On Point Cloud Quality, Jordyn Stoddard

Theses

The adoption of cube-satellites (cubesats) by the space community has drastically lowered the cost of access to space and reduced the development lifecycle from the hundreds of millions of dollars spent on traditional decade-long programs. Rapid deployment and low cost are attractive features of cubesat-based imaging that are conducive to applications such as disaster response and monitoring. One proposed application is 3D surface modeling through a high revisit rate constellation of cubesat imagers. This work begins with the characterization of an existing design for a cubesat imager based on ground sampled distance (GSD), signal-to-noise ratio (SNR), and smear. From this …

Emptying The Silo, Entering The 21st Century : Librarians Engaged In Service Learning, Elizabeth Heffington, Christin Shatzer

The Colloquium on Libraries & Service Learning

Keywords: librarian, service learning, engagement, 21^st century, cultural shift

Through an active learning session, this presentation will discuss the experience of a librarian at Lipscomb University who teaches a service learning course in Freshman Seminar. Credit earned in this course fulfills part of the comprehensive SALT (Serving and Learning Together) graduation requirement. The characteristics and culture of service learning complement the characteristics and culture of academic librarians. The added value of active library participation in the SALT program to students, their increased engagement with the university library, and the ultimate goal of student retention will be addressed.

At face …

Mothers Of The Bible, University Of Dayton. Marian Library

Marian Library Exhibit Summaries

Archived website and summary of exhibit in the Marian Library

Artist: Ginny Baughman

Exhibit dates: August 11 – October 31, 2014

Wildwood Illume, Purling Water, Cecily Nicholson

The Goose

Poetry by Cecily Nicholson.

Mythcon 45 - Where Fantasy Fits, The Mythopoeic Society

Mythcon Programs

Fantasy literature does not fit comfortably into any scheme. Both old and new, traditional and innovative, popular and elite, mainstream and esoteric, escapist and engaged, high-tech and anti-technology, fantasy defies definitions and transcends categories, dramatizing the incompleteness of our understanding of our own imaginations. At Mythcon 45 we will discuss the place of fantasy in our culture, our institutions, and our hearts.

Tombusvirus-Yeast Interactions Identify Conserved Cell-Intrinsic Viral Restriction Factors, Zsuzsanna Sasvari, Paulina Alatriste Gonzalez, Peter D. Nagy

Plant Pathology Faculty Publications

To combat viral infections, plants possess innate and adaptive immune pathways, such as RNA silencing, R gene and recessive gene-mediated resistance mechanisms. However, it is likely that additional cell-intrinsic restriction factors (CIRF) are also involved in limiting plant virus replication. This review discusses novel CIRFs with antiviral functions, many of them RNA-binding proteins or affecting the RNA binding activities of viral replication proteins. The CIRFs against tombusviruses have been identified in yeast (Saccharomyces cerevisiae), which is developed as an advanced model organism. Grouping of the identified CIRFs based on their known cellular functions and subcellular localization in yeast …

Epoxide-Mediated Differential Packaging Of Cif And Other Virulence Factors Into Outer Membrane Vesicles, A. E. Ballok, L. M. Filkins, J.. M. Bomberger, B. A. Stanton, George A. O'Toole

Dartmouth Scholarship

Pseudomonas aeruginosa produces outer membrane vesicles (OMVs) that contain a number of secreted bacterial proteins, including phospholipases, alkaline phosphatase, and the CFTR inhibitory factor (Cif). Previously, Cif, an epoxide hydrolase, was shown to be regulated at the transcriptional level by epoxides, which serve as ligands of the repressor, CifR. Here, we tested whether epoxides have an effect on Cif levels in OMVs. We showed that growth of P. aeruginosa in the presence of specific epoxi

Consumer Behavior In The Online Context, Shannon Cummins, James W. Peltier, John A. Schibrowsky, Alexander Nill

Marketing & Entrepreneurship Faculty Publications

The purpose of this article is to review the consumer behavior and social network theory literature related to the online and e-commerce context.

Design/methodology/approach

To conduct the review, the authors draw on a sample of 942 articles published from 1993 to 2012 addressing consumer behavior or social network issues in the online or social media context. The sample is analyzed by both era (incubation, expansion and explosion) and primary topic.

Findings

Eight categories of online consumer behavior research are described. In the order from largest to smallest, these are: cognitive issues, user-generated content, Internet demographics and segmentation, online usage, cross …

Arts & Humanities News, Georgia Southern University

Arts & Humanities: News & Publications (2009-2023)

• Joseph Peragine responds to environmental stewardship
• Derrick Buisch highlights popular culture in paintings, drawings

Synthesizing The Vertical And The Horizontal: A World-Ecological Analysis Of 'The Industrial Revolution', Part I, Christopher R. Cox

Dissertations and Theses

'The Industrial Revolution' is simultaneously one of the most under-examined and overly-simplified concepts in all of social science. One of the ways it is highly under-examined is in the arena of the ecological, particularly through the lens of critical world-history. This paper attempts to analyze the phenomenon through the lens of the world-ecology synthesis, in three distinct phases: First, the history of the conceptualization of the Industrial Revolution is examined at length, paying special attention to the knowledge foundations that determine these conceptualizations. Secondly, I sift out what I believe is the dominant model throughout most of modern …

Dendritic Cell-Mediated, Dna-Based Vaccination Against Hepatitis C Induces The Multi-Epitope-Specific Response Of Humanized, Hla Transgenic Mice, Sasmita Mishra, Bianca J. Lavelle, Joe Desrosiers, Matt T. Ardito, Frances Terry, William D. Martin, Anne S. De Groot, Stephen H. Gregory

Institute for Immunology and Informatics Faculty Publications

Hepatitis C virus (HCV) is the etiologic agent of chronic liver disease, hepatitis C. Spontaneous resolution of viral infection is associated with vigorous HLA class I- and class II-restricted T cell responses to multiple viral epitopes. Unfortunately, only 20% of patients clear infection spontaneously, most develop chronic disease and require therapy. The response to chemotherapy varies, however; therapeutic vaccination offers an additional treatment strategy. To date, therapeutic vaccines have demonstrated only limited success. Vector-mediated vaccination with multi-epitope-expressing DNA constructs alone or in combination with chemotherapy offers an additional treatment approach. Gene sequences encoding validated HLA-A2- and HLA-DRB1-restricted epitopes were synthesized …

Summer Internships Remain Popular With Students, Danielle Kamp

News and Events (Discontinued Series)

No abstract provided.

Sonaranos Refractions, Kathleen Brown

The Goose

Poetry by Kathleen Brown.

Tap The Screen: Technology Integration In Our Students’ Lives, Matthew J. Fuller

Dissertations

The focus of this study is to document and describe the integration of technology in the everyday lives of students in Grades 3–8 attending a high-performing public school district in an affluent Chicago suburb. The following research questions guide this study:

• How do students in Grades 3–8 integrate technology into their lives?
• What are the implications of students’ technology integration for teaching and learning?
• How can teachers capitalize upon students’ technology integration in ways that inform instructional practice?

A review of the literature presents related information in areas that explore the increasingly digital world of our students; curriculum, instruction, and …