Digital Commons Network^™

Huwe1 Is A Molecular Link Controlling Raf-1 Activity Supported By The Shoc2 Scaffold, Eun Ryoung Jang, Ping Shi, Jamal Bryant, Jing Chen, Vikas Dukhande, Matthew S. Gentry, Hyein Jang, Myoungkun Jeoung, Emilia Galperin

Molecular and Cellular Biochemistry Faculty Publications

Scaffold proteins play a critical role in controlling the activity of the extracellular signal-regulated kinase 1/2 (ERK1/2) pathway. Shoc2 is a leucine-rich repeat scaffold protein that acts as a positive modulator of ERK1/2 signaling. However, the precise mechanism by which Shoc2 modulates the activity of the ERK1/2 pathway is unclear. Here we report the identification of the E3 ubiquitin ligase HUWE1 as a binding partner and regulator of Shoc2 function. HUWE1 mediates ubiquitination and, consequently, the levels of Shoc2. Additionally, we show that both Shoc2 and HUWE1 are necessary to control the levels and ubiquitination of the Shoc2 signaling partner, …

Mckee Minute October 2014, Southern Adventist University

McKee Minute – McKee Library This Month

The October 2014 McKee Minute announces a coming author presentation and library game nights. This edition features books on the theme "Captivating Art," films on English literature, periodicals on art and design, and a spotlight on religion.

How Discordant Morphological And Molecular Evolution Among Microorganisms Can Revise Our Notions Of Biodiversity On Earth, Daniel J.G. Lahr, Haywood Dail Laughinghouse, Angela M. Oliverio, Feng Gao, Laura A. Katz

Biological Sciences: Faculty Publications

Microscopy has revealed tremendous diversity of bacterial and eukaryotic forms. Recent molecular analyses show discordance in estimates of biodiversity between morphological and molecular analyses. Moreover, phylogenetic analyses of the diversity of microbial forms reveal evidence of convergence at scales as deep as interdomain: morphologies shared between bacteria and eukaryotes. Here, we highlight examples of such discordance, focusing on exemplary lineages such as testate amoebae, ciliates, and cyanobacteria. These have long histories of morphological study, enabling deeper analyses on both the molecular and morphological sides. We discuss examples in two main categories: (i) morphologically identical (or highly similar) individuals that are …

An Rnai-Based Suppressor Screen Identifies Interactors Of The Myt1 Ortholog Of Caenorhabditis Elegans, Anna Allen, Jessica Nesmith, Andy Golden

Department of Biology Faculty Publications

Oocyte maturation in all species is controlled by a protein complex termed the maturation promoting factor (MPF). MPF is comprised of a cyclin-dependent kinase (CDK) and its partner cyclin, and is regulated by dueling regulatory phosphorylation events on the CDK. In Caenorhabditis elegans, the Wee1/Myt1 ortholog WEE-1.3 provides the inhibitory phosphorylations on CDK-1 that keep MPF inactive and halts meiosis. Prior work has shown that depletion of WEE-1.3 in C. elegans results in precocious oocyte maturation in vivo and a highly penetrant infertility phenotype. This study sought to further define the precocious maturation phenotype and to identify novel interactors with …

Inconversation, Lyndall Adams, Claire Alexander, Emily Alexander, Frances Barbe, Majella Barbe, Megan Moe Beitiks, Gemma Ben-Ary, Anna Bowen, Heather Boyd, Melisa Charenko, Danna Checksfield, Nandi Chinna, Katie Chown, Lucinda Coleman, Hannah Conda, Samantha Crameri-Miller, Paddi Creevey, Wayne Cristaudo, Cornelius Delaney, Leonie Dunlop, Mace Francis, Rusty Geller, Sue Girak, Miik Green, Louise Helfgott, Catherine Higham, Rebecca Ingram, Teresa Izzard, Marija Jukic, Christopher Kueh, Jacob Lehrer, Carolyne Lewis, Johannes Luebbers, J Scott Macivor, Alex Mckee, Vahri Mckenzie, Gabrielle Metcalf, Nick Mortime, Astrida Neimanis, Renée Newman-Storen, Charity Ng, Finn Pedersen, Perdita Phillips, Marcella Polain, Sarah Robinson, Nien Schwarz, Liz Stops, Rochelle Summerfield, Sharon Thompson, Paul Uhlmann, Mats Undén, George Walley, Min Zhu

ECU Books

inConversation was a collaborative exhibition amongst creative higher degree by research candidates (from the School of Communications and Arts and the Western Australian Academy of Performing Arts), local, national and international arts practitioners and researchers from different art forms and discipline backgrounds. The exhibition invited conversations between artists and researcher collaborators working together to produce a broad range of creative works, culminating in an exhibition titled inConversation, staged at Edith Cowan University’s Spectrum Project Space in October 2014.

The context for the inConversation exhibition aimed to inform and expand on current debates about the challenges and benefits of inter- and …

Imo's Contribution To International Law Regulating Maritime Security, Felicity Attard

Journal of Maritime Law and Commerce

No abstract provided.

Against Divine Truthmaker Simplicity, Noël B. Saenz

Faith and Philosophy: Journal of the Society of Christian Philosophers

No abstract provided.

Probability, Professionalism, And Protecting Taxpayers, Bradley T. Borden, Dennis J. Ventry

Faculty Scholarship

No abstract provided.

Reading Du Bois On East Africa: Epistemological Implications Of Apartheid Constructions Of Knowledge, Jesse Benjamin

Faculty Articles

This paper "reads" the scholarship of W. E. B. Du Bois and references East African history and historiography, including the broader pan-African tradition of which Du Bois was a leading member. Du Bois and his pan-African colleagues were often more accurate in their analyses and perception of biases and colonial myths than their Western counterparts. What is significant is that biases and myths that existed some fifty or more years before acknowledgement in the academy persist today, which raises important questions about the relationship between epistemology and identity, and between racial consciousness and the politics of academic production.

Welcome From The President In Program For Scla Conference 2014, “Unbound”, Edward J. Rock

Publications

SCLA 2014 Conference program welcome from SCLA President, Ed Rock. Program describes the scope of the 2014 conference of the South Carolina Library Association (SCLA). Includes titles of conference sessions, names of presenters, descriptions of topics and list of sponsors and exhibitors, as well as the overall conference program including keynote speakers Ed Madden, University of South Carolina Poet/Professor; George Needham, OCLC; and Sanford Greene, Illustrator/Author.

'Work Itself Is Given A Voice': Labor, Deskilling, And Archival Capability In The Poetry Of Kenneth Goldsmith And Mark Nowak, Michael Leong

Reconstruction: Studies in Contemporary Culture

[First paragraph]

The title of Mary Ann Caws' recent article "Poetry Can Be Any Damn Thing It Wants" blithely, but no less accurately, indicates the anarchic condition, both liberatory and destabilizing, of contemporary North American poetry production-particularly in the way it speaks to the recent and controversial trend of conceptual poetry, which eschews the fragmentation and lexical, semantic, and syntactic difficulty that is the heritage of the so-called L=A=N=G=U=A=G=E group in favor of a resolutely anti-literary poetics of plagiarism, appropriation, and the readymade [1]. Indeed, Caws' title highlights the sheer nominating power of the poet: the conceptualist's animating concept takes …

Taste In Pope’S The Dunciad: A Bourdiesian Reading, Hossein Pirnajmuddin, Ebrahim Zarei

Reconstruction: Studies in Contemporary Culture

Alexander Pope as the most representative poet of his age is very much concerned with 'high' and 'low' culture and art. He ascribes socio-cultural decline to vulgar taste in literature and criticism. An exemplar poem in which he addresses the matter of taste is The Dunciad in which the poet traduces and censures some of his contemporary literary figures, excoriating them for producing works which according to him promulgate vulgar taste and aestheticism. Pierre Bourdieu has stressed the overarching significance of taste in classifying people into different strata and social spaces. Arguing for the centrality of the notion of taste …

Game Studies Round Table, Judd Ethan Ruggill, Tobias Conradi, Steven Conway, Ken S. Mcallister, Rolf F. Nohr, Theo Röhle

Reconstruction: Studies in Contemporary Culture

[First paragraph]

This conversation began as a salon that was convened in February 2014, just after the 35th annual conference of the Southwest Popular/American Culture Association (SWPACA). The theme for the salon was localism, with a principal focus on how the field of game studies is arrayed across countries, institutions, and time. The participants spanned the experiential spectrum from post doctoral researcher to dean, and represented three of the most developed regions in game studies and the industry it analyzes: Europe (Germany), Australia, and the U.S. The questions were prepared in advance by Ken McAllister and Judd Ruggill, who moderated …

The Transfenestrational Imaginary: Periodizing Vineland’S Sixties, Johanna Isaacson

Reconstruction: Studies in Contemporary Culture

"The Transfenestrational Imaginary: Periodizing Vineland's Sixties" argues that the representational strategy in Vineland has much in common with Fredric Jameson's sixties periodization strategy, and offers a sustained analogy between narrative strategy and historiography. I suggest that Vineland is most productively seen as a continuation of the anti-literary genres of the sixties underground press and manifesto forms, genres that were necessarily temporary and politicized, and became opaque when separated from the context of active political social movements. The paper focuses on two key figures in the novel, Frenesi Gates and Zoyd Wheeler, and argues that the two are associated with …

Contesting Boundaries In Toni Morrison’S Beloved, Will Cunningham

Reconstruction: Studies in Contemporary Culture

[First paragraph]

Toni Morrison dedicates Beloved to the "Sixty Million and more" captured, displaced, and murdered Africans whose physical lives and cultural identity were terminated amidst the transatlantic slave trade. Morrison's invocation of the transatlantic slave trade frames the story of Beloved within the context of spatialized violence - a complex, industrial and capitalistic endeavor that specifically targeted black identity. The belly of the slave ship, an image invoked in Beloved's monologue, is a precursor to more familiar, albeit less violent, modern spaces that might be demarcated as placeless: international airport terminals and borders, refugee camps, and military detention prisons. …

Review Of Eat It: Sex, Food And Women's Writing, Edited By Nicole Baute And Brianna Goldberg, Marc Ouellette

Reconstruction: Studies in Contemporary Culture

[First paragraph]

Simply put, Eat It: Sex, Food and Women's Writing surpasses its rather immodest claims. This is no mean feat, for the editors allow that they have collected short stories, non-fiction shorts and poetry that, as the back claims offers, hinge "on the carnal." More than that, the gathered works purportedly address the ways in which experiencing food entails nothing short of "power, biology, social obligation, experimentation, nourishment, pain and pleasure." The authors treat the topics, ranging from the politics of potatoes to tricks for field dressing deer, with a blend of seriousness and humour befitting the material. What …

Remapping The Present: Dave Eggers's Spatial Virtuality And The Condition Of Literature, Nathan Frank

Reconstruction: Studies in Contemporary Culture

Piggy-backing on the spatial turn in literary studies, this paper "remaps the present" by making a parallel spatial turn in virtual theory. Surveying and synthesizing the many invaluable contributions to conceptualizing virtuality - from those of Bergson and Deleuze through to those of Daniel Downes and Brian Massumi - a "spatial virtuality" accounts for an increasing focus on digitization without dismissing the previous (and, at times, prescient) preoccupations with temporal virtualities. But I also frame spatial virtuality in terms of N. Katherine Hayles' compelling work in which virtuality is a condition. Within such a framework, many things happen, not the …

The Private Roots Of American Political Development: The Immigrants' Protective League's “Friendly And Sympathetic Touch,” 1908–1924, Carol Nackenoff

Political Science Faculty Works

This article aims to illuminate how non-state actors participate in forging public institutions and in establishing public agendas. It also sets out to identify novel mechanisms of state building. It does so by examining the historical experience of the Immigrants' Protective League (IPL) from its founding in 1908 through 1924. The history of the IPL highlights the role of organized, networked women in generating new boundary stories and doing boundary work; in conducting research and enhancing legibility; in incubating new policy experiments; and in moving the national, state, and local governments to take up new tasks in the progressive era. …

Spectator 2014-10-01, Editors Of The Spectator

The Spectator

No abstract provided.

Montanan, Fall 2014, University Of Montana--Missoula

Montanan Magazine, 1969-2024

This is the magazine of the University of Montana with news about the University for UM alumni as well as current faculty, students, staff, and administrators. This is volume 31, number 3.

A Domestic Proposal To Revive The Hague Judgments Convention: How To Stop Worrying About Streams, Trickles, Asymmetry, And A Lack Of Reciprocity, Eric Porterfield

Duke Journal of Comparative & International Law

No abstract provided.

Diagnostic Value Of Musculoskeletal Ultrasound In Acute And Chronic Lateral Epicondylalgia, Valentine Dones Iii, Karen Grimmer, Steven Milanese, Consuelo Suarez, Kerry Thoirs, Saravana Kumar

Internet Journal of Allied Health Sciences and Practice

Introduction: The literature suggests that abnormal sonographic findings of the common extensor origin (hypoechogenicity, neovascularity, calcifications, irregular margin, presence of adjacent fluid, irregular fibrillar pattern, thickness, tear) and of the lateral epicondyle (cortical irregularities) can be used to confirm the presence of Lateral Epicondylalgia (LE) in elbows which have been initially diagnosed using the clinical diagnosis for LE. The association of these abnormal sonographic findings and the initial clinical diagnosis for LE were studied. Methodology: The participants were recruited in Metro Manila (Philippines) through advertisements and referral by doctors and physiotherapists. LE was determined if participants reported lateral elbow pain …

Fairness In Law And Economics: Introduction, Lee Anne Fennell, Richard H. Mcadams

Public Law and Legal Theory Working Papers

No abstract provided.

Vocal Fold Epithelial Barrier In Health And Injury: A Research Review., Elizabeth E. Levendoski, Ciara Leydon, Susan L. Thibeault

Communication Disorders Faculty Publications

Purpose: Vocal fold epithelium is composed of layers of individual epithelial cells joined by junctional complexes constituting a unique interface with the external environment. This barrier provides structural stability to the vocal folds and protects underlying connective tissue from injury while being nearly continuously exposed to potentially hazardous insults, including environmental or systemic-based irritants such as pollutants and reflux, surgical procedures, and vibratory trauma. Small disruptions in the epithelial barrier may have a large impact on susceptibility to injury and overall vocal health. The purpose of this article is to provide a broad-based review of current knowledge of the vocal …

Roma And Czechs: Mindful Of Difference, Matthew Richard

Southern Anthropologist

This essay applies theory and method developed over the past two decades by a number of cognitively- and psychologically-oriented social scientists to explore antipathy between Czechs and Roma in the present-day Czech Republic. It investigates how Czech understandings of personhood and otherness are variously organized, acquired, and practiced. Although ethnic hatred continues to be a problem in the Czech Republic, recent findings in psychological anthropology advise against assuming that it is reproduced wholesale from one generation to the next—nor even one instant to the next. The main source of data is the narratives of twenty-five young Czechs, who recall their …

Sfa Gardens Newsletter, Fall 2014, Sfa Gardens, Stephen F. Austin State University

SFA Gardens Newsletters

No abstract provided.

Writing Together: An Arendtian Framework For Collaboration, Jessica Restaino

Department of Writing Studies Faculty Scholarship and Creative Works

This essay considers the long-standing challenges, in both practice and theory, to collaborative writing in the first-year classroom. I argue that Hannah Arendt’s concepts of plurality and natality are useful frameworks for thinking constructively and practically about teaching argumentative writing through collaboration. I explore these concepts in terms of foundational scholarship on written collaboration, such as Candace Spigelman’s work on writing groups and intellectual property, as well as recent considerations of evolving technological resources (Howard). Ultimately, thinking through Arendt, I offer examples from my own classroom practice, and also generate a series of questions designed to support instructors’ incorporation of …

The Guardian, October 1, 2014, Wright State University Student Body

The Guardian Student Newspaper

Twelve page issue of The Guardian, the official student-run newspaper for Wright State University. The Guardian has been published regularly since March of 1965.

Medicine And Doctoring In Ancient Mesopotamia, Emily K. Teall

Grand Valley Journal of History

Medicine and pharmaceuticals in Mesopotamia during the span of c. 3000-1000 BCE were more sophisticated than many ancient and modern scholars from other cultures would concede. The limited historical evidence in the form of cuneiform texts and the complementary archaeological material allow for medical practice in this long time span to be examined as a whole. There were two dichotomous traditions of healing present in ancient Mesopotamia, one more therapeutic and one more religious; they were non-competitive and both considered reputable and essential. The therapeutic tradition is given a closer examination in order to provide a picture of how pharmaceutical …

John Of Salisbury's Metalogicon And The Equality Of Liberal Arts Education, Abigail E. Dehart

Grand Valley Journal of History

When examining the historical development of society, perhaps the most determining factor is education. During the development of Western education, there is, conceivably, no time more formative to modern views of education than the Middle Ages, for out of it emerged the first universities, and with that, what has contributed largely to today’s concept of general education programs. Of the Middle Ages, the twelfth century was particularly formative to the shaping of education, and has even been called the birthplace of Western pedagogy. One of the best twelfth-century sources we have regarding this time in history is John of Salisbury’s …