Digital Commons Network^™

The Language Of Mens Rea, Kenneth Simons, Matthew R. Ginther, Francis X. Shen, Richard J. Bonnie

Faculty Scholarship

This article answers two key questions. First: Do jurors understand and apply the criminal mental state categories the way that the widely influential Model Penal Code (MPC) assumes? Second: If not, what can be done about it?

Principled Standards Vs. Boundless Discretion: A Tale Of Two Approaches To Intermediary Trademark Liability Online, Stacey Dogan

Faculty Scholarship

Over the past decade, courts have developed two distinct approaches in evaluating trademark claims against online intermediaries. In one – contributory infringement – courts struggle with the tension between preserving legitimate, non-infringing uses of technologies, on the one hand, and minimizing infringement, on the other. In the other – direct infringement – liability turns on perceived wrongdoing by intermediaries whose own behavior increases the risk of consumer confusion. This second type of liability boasts neither a clear doctrinal framework nor a coherent normative vision. Most troublingly, the scant case law has paid little attention to issues at the core of …

Social Constructs In Film Culture: The Effect Of It On The Performing Arts, And The Destroyed Association Of Signs To Enhance Meaning, Eileen W. Tom

University Honors Theses

Semiotics is the study of signs and how they produce meaning in society. How can the lens of semiotics (specifically the components and the relationship between the signifier and the signified) reform the audience and performer systems? This thesis serves as an examination of the relationship between the audience and performer, how each play a part in creating meaning within a given performance piece. This project provides a method on how to rebuild the world of the film to enhance a theme. The primary evidence consists of statistics gathered from a viewing of a staged reading that was written specifically …

A Test Of The Optimal Defense Theory: Cyanogenesis In Phaseolus Lunatus L., Lauren M. Stady

University Honors Theses

The optimal defense theory describes an ideal distribution of chemical defense patterns in plants. Chemical defenses are finite, and should be allocated based upon the vulnerability and value of a given tissue. In this study, we quantified hydrogen cyanide production (defense parameter) and protein content (nutritive parameter) in photosynthetic and reproductive organs of experimental plant Phaseolus lunatus L.. Feeding trials using a generalist herbivore were also conducted to determine insect preference, and compare against defense and nutritional values obtained. Our findings show that young leaves have highest concentrations of hydrogen cyanide, and are thus best defended, and reproductive organs and …

"L'Affaire Des Princes": Baroque Architecture And Factional Politics In Regency Paris, 1715-1723, Jordan Hallmark

University Honors Theses

It has long been noted by architectural historians that the exuberant stylistic idiom of the Roman Baroque, which spread throughout most of Europe in the seventeenth and early eighteenth centuries, failed to exert much of an influence on the architecture of early modern France. Scholars have traditionally interpreted this failure as a conscious rejection of the Roman Baroque style on the part of the French monarchy, which, with the rise of royal absolutism during the personal reign of Louis XIV (1661-1715) , adopted the classical style of architecture and design as a formal language with which to assert the absolute …

Neuropeptide Y: A Potential Marker For A Life-History Transition In The Red-Sided Garter Snake (Thamnophis Sirtalis), Daelyn Richards

University Honors Theses

It is essential for organisms to exhibit appropriate behaviors as they transition from one life-history stage to another. While such life-history transitions are critical to both individual survival and reproductive fitness, we know very little about the underlying mechanisms. This project explores a potential mechanism regulating the transition of red-sided garter snakes (Thamnophis sirtalis) from reproductive to foraging behavior. After emerging from winter dormancy, male snakes engage in mate searching and mating behavior followed by a transition to foraging. Neuropeptide Y (NPY) is a neurohormone that controls appetite and feeding behavior in all organisms studied. We previously demonstrated …

Evolutionary Potential Of Marine Phytoplankton Under Ocean Acidification, Sinéad Collins, Björn Rost, Tatiana A. Rynearson

Graduate School of Oceanography Faculty Publications

Marine phytoplankton have many obvious characters, such as rapid cell division rates and large population sizes, that give them the capacity to evolve in response to global change on timescales of weeks, months or decades. However, few studies directly investigate if this adaptive potential is likely to be realized. Because of this, evidence of to whether and how marine phytoplankton may evolve in response to global change is sparse. Here, we review studies that help predict evolutionary responses to global change in marine phytoplankton. We find limited support from experimental evolution that some taxa of marine phytoplankton may adapt to …

Mercury Bioaccumulation In Cartilaginous Fishes From Southern New England Coastal Waters: Contamination From A Trophic Ecology And Human Health Perspective, David L. Taylor, Nicholas J. Kutil, Anna J. Malek, Jeremy S. Collie

Graduate School of Oceanography Faculty Publications

This study examined total mercury (Hg) concentrations in cartilaginous fishes from Southern New England coastal waters, including smooth dogfish (Mustelus canis), spiny dogfish (Squalus acanthias), little skate (Leucoraja erinacea), and winter skate (Leucoraja ocellata). Total Hg in dogfish and skates were positively related to their respective body size and age, indicating Hg bioaccumulation in muscle tissue. There were also significant inter-species differences in Hg levels (mean ± 1 SD, mg Hg/kg dry weight, ppm): smooth dogfish (3.3 ± 2.1 ppm; n = 54) > spiny dogfish (1.1 ± 0.7 ppm; n = 124) …

Endogenous Ros Levels In C. Elegans Under Exogenous Stress Support Revision Of Oxidative Stress Theory Of Life-History Tradeoffs, Samson W. Smith, Leigh C. Latta Iv, Dee R. Denver, Suzanne Estes

Biology Faculty Publications and Presentations

Background: The oxidative stress theory of life-history tradeoffs states that oxidative stress caused by damaging free radicals directly underpins tradeoffs between reproduction and longevity by altering the allocation of energetic resources between these tasks. We test this theory by characterizing the effects of exogenous oxidative insult and its interaction with thermal stress and diet quality on a suite of life-history traits and correlations in Caenorhabditis elegans nematodes. We also quantify demographic aging rates and endogenous reactive oxygen species (ROS) levels in live animals.

Results: Our findings indicate a tradeoff between investment in reproduction and antioxidant defense (somatic maintenance) consistent with …

Reading John Noonan, Jospeh Vining

Articles

John Noonan is a giant in American law and legal practice -- a distinguished legal historian and a true judge. His reflections on the nature of law have a special importance. This essay is a comment on basic elements in his thought.

Concentrated Ownership And Corporate Control: Wallenberg Sphere And Samsung Group, Hwa-Jin Kim

Articles

Samsung Group’s success cannot be attributed to its corporate governance structure, at least thus far. The corporate governance of Samsung has been rather controversial. As the group faces the succession issue the corporate governance has become as crucial as their new products and services. Samsung has discovered a role model on the other side of the planet, Wallenberg Sphere in Sweden. Much effort has been made to learn about Wallenberg’s arrangements and key to its success. However, a fundamental difference between the institutions in Sweden and Korea has made the corporate structures of the two groups radically different. Wallenberg uses …

The Tempting Of Antitrust: Robert Bork And The Goals Of Antitrust Policy, Daniel A. Crane

Articles

Of all Robert Bork’s many important contributions to antitrust law, none was more significant than his identification of economic efficiency, disguised as consumer welfare, as the sole normative objective of U.S. antitrust law. The Supreme Court relied primarily on Bork’s argument that Congress intended the Sherman Act to advance consumer welfare in making its landmark statement in Reiter v. Sonotone that “Congress designed the Sherman Act as a ‘consumer welfare prescription.’” This singular normative vision proved foundational to the reorientation of antitrust law away from an interventionist, populist, Brandeisian, and vaguely Jeffersonian conception of antitrust law as a constraint on …

Investigation Of Pyrrolizidine Alkaloids In Foods Using Liquid Chromatography Mass Spectrometry, Caroline Griffin

PhDs

Pyrrolizidine Alkaloids (PAs) are known plant toxins which can cause hepatic veno-occlusive disease (HVOD) in both humans and livestock when ingested. Although PAs are primarily known for their hepatotoxicity they also induce genotoxicity, carcinogenicity and pneumotoxicity. PAs are consumed through plants as food, for medicinal purposes, or as contaminants of agricultural crops. Aside from ingesting the plants directly PA exposure may occur through the consumption of honey produced by bees that visit PA-containing plants or by drinking milk produced by animals that have consumed PA-containing plants. Possible PA contamination in our food chain is a potential health risk.

To assess …

Host Behavior Alters Spiny Lobster-Viral Disease Dynamics: A Simulation Study, Thomas W. Dolan Iii, Mark J. Butler Iv, Jeffrey D. Shields

Biological Sciences Faculty Publications

Social behavior confers numerous benefits to animals but also risks, among them an increase in the spread of pathogenic diseases. We examined the trade-off between risk of predation and disease transmission under different scenarios of host spatial structure and disease avoidance behavior using a spatially explicit, individual-based model of the host pathogen interaction between juvenile Caribbean spiny lobster (Panulirus argus) and Panulirus argus Virus 1 (PaV1). Spiny lobsters are normally social but modify their behavior to avoid diseased conspecifics, a potentially effective means of reducing transmission but one rarely observed in the wild. We found that without lobster avoidance of …

Hidden Diversity In Sardines: Genetic And Morphological Evidence For Cryptic Species In The Goldstripe Sardinella, Sardinella Gibbosa (Bleeker, 1849), Rey C. Thomas, Demian A. Willette, Kent E. Carpenter, Mudjekeewis D. Santos

Biological Sciences Faculty Publications

Cryptic species continue to be uncovered in many fish taxa, posing challenges for fisheries conservation and management. In Sardinella gibbosa, previous investigations revealed subtle intra-species variations, resulting in numerous synonyms and a controversial taxonomy for this sardine. Here, we tested for cryptic diversity within S. gibbosa using genetic data from two mitochondrial and one nuclear gene regions of 248 individuals of S. gibbosa, collected from eight locations across the Philippine archipelago. Deep genetic divergence and subsequent clustering was consistent across both mitochondrial and nuclear markers. Clade distribution is geographically limited: Clade 1 is widely distributed in the central Philippines, while …

Concordant Phylogenetic Patterns Inferred From Mitochondrial And Microsatellite Dna In The Giant Clam Tridacna Crocea, Timery S. Deboer, Ma Rio Abdon Naguit, Mark V. Erdmann, Maria Carmen A. Ablan-Lagman, Ambariyanto, Kent E. Carpenter, Abdul Hamid A. Toba, Paul H. Barber

Biological Sciences Faculty Publications

The boring giant clam, Tridacna crocea Lamarck, 1819, is a CITES-listed bivalve that is declining due to overharvest and environmental degradation. Previous molecular studies in the Coral Triangle using mitochondrial DNA indicated the presence of deep phylogenetic divergence and strong phylogeographic structure across this region, suggesting the possibility of multiple cryptic species. In the present study, we compare data from non-recombining mitochondrial (mtDNA; cytochrome oxidase subunit 1, COI) and eight microsatellite loci to better understand patterns of genetic structure and species boundaries in T. crocea populations across Indonesia and the Philippines. Microsatellite loci and mtDNA data from 618 individuals representing …

Tick-Bourne Pathogens Of Potential Zoonotic Importance In The Southern African Region, Simbarashe Chitanga, Holly Gaff, Samson Mukaratirwa

Biological Sciences Faculty Publications

The aim of this communication is to provide preliminary information on the tick-borne pathogens of potential zoonotic importance present in southern Africa, mainly focusing on their geographical distribution and host range, and to identify research gaps. The following tick-borne zoonoses have been reported to occur in southern Africa based mainly on case reports: Crimean–Congo haemorrhagic fever caused by Crimean–Congo haemorrhagic fever virus; ehrlichiosis caused by Ehrlichia ruminantium, Ehrlichia canis and Anaplasma phagocytophilum; babesiosis caused by Babesia microti; relapsing fever caused by Borrelia duttonii and rickettsioses caused by Rickettsia africae, Rickettsia aeschlimannii and Rickettsia conorii. The …

Nesting Ecology Of White-Throated Sparrows (Zonotrichia Albicollis) : The Effects Of Variation In Clutch-Initiation Date And The Application Of Prescribed Fire On Nesting Success, Melissa Olmstead

Theses and Dissertations (Comprehensive)

The study of nesting success is one of the most widely-used methods for examining the factors governing recruitment in birds. Many ecological influences act together to increase or decrease nesting success, and knowledge of these mechanisms is crucial for determining the habitat or conservation requirements of a given species. One ecological influence is the timing of breeding, which in many species is related to a decline in nest success later in the breeding season. Much of the research on this subject has focused on cavity-nesting species, and the hypothesis that this seasonal decline is caused by a mismatch between clutch-initiation …

The Role Of Body Size On The Outcome Of Mating Interactions In Drosophila Melanogaster, Adam C. Lounsbury

Theses and Dissertations (Comprehensive)

Sexual selection is the process by which some individuals produce more and/or better quality offspring than others because they are better at securing mates. While this may be accomplished by defeating same-sex rivals (intrasexual selection), individuals of one sex (typically females) may also “decide” on the suitability of individuals of the opposite sex (typically males), resulting in intersexual selection on attractive traits. While a great deal of scrutiny has focused on how sexual selection influences male display traits, much less scrutiny has been directed toward the factors underlying female preference, including genetic variation, as well as the extent to which …

The Establishment Of A Fibroblastic Cell Line From Yellow Perch (Perca Flavescens) And Its Potential Applications In Toxicology, Katelin W. Spiteri

Theses and Dissertations (Comprehensive)

This thesis describes the establishment, characterization and potential toxicological applications of YPF5, a yellow perch cell line. YPF5 is a fibroblastic cell line derived from the caudal fin of yellow perch. This cell line has been maintained for over 2 years. Cultures have been passaged over 60 times, and successfully cryopreserved and thawed. YPF5 is grown at room temperature in Leibovitz-15 (L-15) media, supplemented with 10% fetal bovine serum and 3% penicillin-streptomycin. The origin of YPF5 has been confirmed as Perca flavescens through “DNA Barcoding” and reaffirmed through Karyotyping (2n = 48) as per literature reported karyology for percidae including …

Effects Of Salinity And Dissolved Organic Matter On Cu Toxicity To Americamysis Bahia In Estuarine Environments, Rabia Nasir

Theses and Dissertations (Comprehensive)

As salinity increases the geochemical speciation of Cu is altered as a result of organic/inorganic complexation/competition. Such salinity changes may further challenge the osmoregulatory capabilities of euryhaline organisms. This chemical-biological interaction complicates the understanding of the impacts of Cu in estuarine waters. Dissolved organic matter (DOM) has been widely established to be an important modifier of Cu toxicity in freshwaters however its effectiveness in modulating Cu toxicity across the range of salinities that occur in estuarine conditions has not been studied in a systematic manner. Site to site differences in DOM quality with respect to the potential for toxicity mitigation …

Distribution And Elimination Of 3-Trifluoromethyl-4-Nitrophenol (Tfm) By Sea Lamprey (Petromyzon Marinus) And Non-Target, Rainbow Trout (Oncorhynchus Mykiss) And Lake Sturgeon (Acipenser Fulvescens), Michael W. Le Clair

Theses and Dissertations (Comprehensive)

The pesticide, 3-trifluoromethyl-4-nitrophenol (TFM), has been highly successful in the control of sea lamprey (Petromyzon marinus) populations in the Great Lakes. Treatments with TFM involve applying it to streams, where it targets larval sea lamprey which live burrowed in the stream substrate. While the toxic mechanism of TFM has been elucidated, and its effects on sea lamprey described, its effects on non-target fish species such as rainbow trout (Oncorhynchus mykiss) and lake sturgeon (Acipenser fulvescens) are not as well understood. The present work demonstrated that rainbow trout show a great capacity to detoxify the lampricide using glucuronidation, when exposed to …

Characterizing Dsrna Production In Virus-Infected Fish Cells, Amal Brek Aloufi

Theses and Dissertations (Comprehensive)

Viral dsRNA is produced by almost all viruses sometime during their replicative cycle. These viral nucleic acids are potent inducers of both innate and adaptive immune responses, and are therefore considered important immuno-modulators. Previous studies have shown that viruses produce dsRNA when replicating in mammalian cells; however, to date no one has demonstrated viral dsRNA production in virus infected fish cells. Therefore, the goal of this study is to investigate dsRNA production by fish viruses in fish cells, verifying production and performing initial characterization of the dsRNA molecules being produced. Three different rainbow trout cell lines were used in this …

Causes And Consequences Of Female Mate Choice In Drosophila Melanogaster: A Hemiclonal Analysis, Hannah Me Tennant

Theses and Dissertations (Comprehensive)

One of Darwin’s greatest questions, the reason why females prefer elaborate sexually selected male traits and displays, was elucidated by the Fisherian coevolution of male traits and female preferences. While variation in male attractiveness and ornamentation has received much attention, there has been little attempt to evaluate the causes and consequences of intraspecific variation in components of female preference. Furthermore, demonstrating a genetic basis to female preference does not answer the question of how within-population genetic variation is maintained.

Understanding the sources of variation in potential mating interactions between males and females is important because this variation determines the strength …

Parent-Child Interaction In Shared-Computer Activities: An Exploratory Study Examining Parent-Child Interaction With A Mobile Device, Marjan Petkovski

Theses and Dissertations (Comprehensive)

The present exploratory study examined the shared-computer behaviours of parent-child dyads in order to examine how (and if) parents interact with their children when using mobile digital devices and parents’ perceptions of their child’s technology use. Little is known about how technologies are used with young children and how to maximize and support young children’s learning when they are introduced to these technologies. In total, ­­104 parents (­­n = 72 mothers and n = 32 fathers; one parent per child) participated in an observation session where parent-child interactions using a mobile device (Apple iPad™) were recorded in order to observe …

“Comfort, Comfort My People”: A Qualitative Study Examining Dying Persons’ And Their Caregivers’ Experience Of Spiritual Care As An Aid To Having A Good Death In Grey And Bruce Counties, Ontario, Dwight Biggs

Theses and Dissertations (Comprehensive)

Dying persons and their caregivers encounter several needs as part of the dying journey. Spiritual care, when offered effectively, can help address many of those needs. When people’s needs are fulfilled, their suffering is lessened and there is an increased possibility of them experiencing a good death. However, when spiritual care is not offered effectively, dying persons and their caregivers often continue to face unalleviated suffering which limits their ability to experience a good death. This research project explores how dying persons and their caregivers experience spiritual care in their homes as an aid to dying well and having a …

Gait Initiation Mechanics In Concussed Varsity Athletes, Adam Harper

Theses and Dissertations (Comprehensive)

Concussions are a common and potentially serious injury that affects athletes across multiple sports. More than ever concussions are now at the forefront of sport-related research.

Current research indicates that in a cohort of Canadian junior hockey players examined during the 2009-2010 season showed a rate of concussion at 36.5% of all athletic injuries (Echlin et al., 2010). This rate of concussion injury indicates that proper evaluations and examination tools are key to successful management of concussions. The objective of this study was to determine whether a functional task such as gait initiation is able to quantify stability difference following …

Pro-Anorexia/Bulimia Interactions Online: Problematizing Complex Cultural Phenomena, Nicole D. Schott

Theses and Dissertations (Comprehensive)

In the West, and increasingly globally, individuals, particularly women, are fixated on weight loss, driven by the goal of achieving a culturally-desired, and aggressively marketed, "skinny" female physique. There are online forums where individuals refer to themselves or their eating disorders as "pro-ana" and "pro-mia". Individuals who post on these sites both align with, and challenge, what medical and mental health professionals define as serious mental health problems that result in severe, sometimes fatal, medical complications. This thesis specifically focuses on interactions with, and within, the pro-ana/mia culture on the social media websites Tumblr and YouTube. Over sixteen months, and …

The Innate Antiviral Effects Of Extracellular Viral Dsrna In Rainbow Trout Cells, Sarah J. Poynter

Theses and Dissertations (Comprehensive)

Viral double-stranded RNA (dsRNA) molecules are a potent pathogen-associated molecular pattern and play a crucial role in the innate immune response. During a viral infection, extracellular and intracellular dsRNA can initiate pathways resulting in the production of type I interferons (IFNs) and interferon-stimulated genes (ISGs). The accumulation of ISGs within a cell results in a protective antiviral state. This study used both commercially available dsRNA (poly I:C) and in vitro transcribed dsRNA molecules, based on the viral hemorrhagic septicemia virus (VHSV) genome sequence, as stimuli to investigate the effects of these molecules on the innate immune response in rainbow trout …

A Bittersweet Investigation Of Availability And Nutritive Value As Determinants Of Volitional Sucrose Consumption, Milan D. Valyear

Theses and Dissertations (Comprehensive)

Rats given ~24 h access to a 4% sucrose solution every 3^rd day (E3DA) consume about 100 g more solution than rats with continuous, everyday access (EDA). Under the same EDA-E3DA conditions rats will consume similar amounts of a more concentrated 8 or 16% sucrose solutions (Eikelboom, Hewitt, & Adams, Unpublished). It maybe that with these more concentrated solutions rats hit a satiety limit that prevents a difference between EDA and E3DA consumption from being evident. Experiment 1 was conducted to investigate the effect of adding quinine to 4% and 8% sucrose solutions with the intention of reducing consumption …