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Dual-Specificity Phosphatase-1 Regulates The Inflammatory Milieu In Head And Neck Squamous Cell Carcinoma, Xiaoyi Zhang

MUSC Theses and Dissertations

Head and neck cancer accounts for approximately 6% of diagnosed malignancies in the United States, with an estimated 35,000 incidences and over 7,000 deaths every year. Head and neck squamous cell carcinoma (HNSCC) comprises the majority of head and neck cancers, with a worldwide incidence of more than 500,000 cases. Head and neck cancer patients often present in advanced stages of disease, and despite ongoing research, survival rates remain lower than other more common malignancies. Cytokines and pro-inflammatory factors have been shown to have a critical role in the various steps of malignant transformation, including tumor growth, survival, invasion, angiogenesis, …

Acute Paraplegia Caused By Schistosoma Mansoni, Hussein A. Algahtani, Ahmed A. Aldarmahi, Mohammed W. Al-Rabia, Saleh S. Baeesa

Neurosciences

Schistosomiasis affects over 200 million people worldwide. Involvement of the CNS is a rare occurrence. We report 2 young males who presented with rapidly progressing paraparesis associated with urinary incontinence. In both cases, MRI of the spine demonstrated a diffusely enhancing mass at the conus medullaris with extensive spinal cord edema. Laboratory investigations revealed mild peripheral eosinophilia and abnormal, but non-specific, CSF analysis. In one patient, the diagnosis was made based on a rising schistosomal titer with a positive rectal biopsy. In the other patient, spinal cord biopsy revealed a granuloma. Both cases were caused by Schistosoma mansoni and patients …

Crossed Cerebro-Cerebellar Atrophy With Dyke Davidoff Masson Syndrome, Hussein A. Algahtani, Ahmed A. Aldarmahi, Mohammed W. Al-Rabia, G. Bryan Young

Neurosciences

Dyke Davidoff Masson syndrome (DDMS) refers to atrophy or hypoplasia of one cerebral hemisphere following a prior fetal or childhood insult. It has characteristics of clinical and radiological changes. These changes include hemiparesis, seizures, facial-asymmetry, and mental retardation. We present a 25-year-old man with crossed cerebrocerebellar atrophy and DDMS. His seizures were well controlled using a combination of antiepileptic drugs.

How Civil Society Represents Women: Feminists, Catholics, And Mobilization Strategies In Africa, Alice J. Kang

Department of Political Science: Faculty Publications

In recent years, civil society has risen to speak on behalf of underrepresented groups in Africa. In particular, civil society has advocated for the representation of women’s interests. Yet, relatively little is known about the full range of actors who seek the representation of women’s interests, mobilize around women’s issues, and articulate specific preferences. Some of these actors include not only feminists, but also religious activists who may clash over women’s issues. This gap in knowledge, moreover, extends to non-democratic countries. Who in civil society seeks to influence the representation of women’s interests and how, in both democratic and authoritarian …

Differences In Negativity Bias Underlie Variations In Political Ideology, John R. Hibbing, Kevin B. Smith, John R. Alford

Department of Political Science: Faculty Publications

Disputes between those holding differing political views are ubiquitous and deep-seated, and they often follow common, recognizable lines. The supporters of tradition and stability, sometimes referred to as conservatives, do battle with the supporters of innovation and reform, sometimes referred to as liberals. Understanding the correlates of those distinct political orientations is probably a prerequisite for managing political disputes, which are a source of social conflict that can lead to frustration and even bloodshed. A rapidly growing body of empirical evidence documents a multitude of ways in which liberals and conservatives differ from each other in purviews of life with …

Selective Versus Comprehensive Emergency Management In Korea, Kyoo-Man Ha, Hyeon-Mun Oh

Department of Political Science: Faculty Publications

In spite of Korean governments’ efforts, many emergency management practitioners wonder whether what is actually being practiced is selective or comprehensive management. Using a qualitative content analysis and experiences in practice, the article analyzes the barriers to selective emergency management and the paths to comprehensive emergency management via the same three management elements: stakeholders, phases of the emergency management lifecycle, and hazards and impacts. Four analytical levels are considered: central government level, industry level, community level, and household level. Korea, despite its self-praise, has to transform its selective emergency management into comprehensive emergency management in time.

No Matter How Small... Property, Autonomy, And State In Horton Hears A Who!, Jorge L. Contreras

NYLS Law Review

No abstract provided.

Reflections On The New Haven School, Molly Land

NYLS Law Review

No abstract provided.

Tennessee Ag Insider, A Guide The The State's Farms, Food, And Forestry, 2014 Edition, Tennessee. Department Of Agriculture.

Tennessee Ag Insider

No abstract provided.

Groundwater Report 305b 2014, Tennessee. Department Of Environment And Conservation.

Groundwater Assessment

No abstract provided.

Gyalthang Southern Khams Tibetan: A Case Study Of Language Attitudes And Shift In Shangri-La, Simon Peters

Anthós

I begin by offering some highlighting certain aspects of Tibetan language variation with particular attention to the local Gyalthang variety. In the following section I introduce Gyalthang’s touristic Old Town and the language situation there, exploring how the highly divergent nature and mutual unintelligibility of Tibetan language varieties inform stakeholder language attitudes. I place Gyalthang Tibetan into the UNESCO framework for assessing language vitality to explore the interactions of these attitudes and the implications they have for the maintenance of the local Tibetan variety. I conclude with a discussion of what language shift in Gyalthang reveals about language shift in …

Some Versions Of Timon's Epitaph: Performance, Text, And Gift In Shakespeare And Middleton's Timon Of Athens, Silas Frederick Pera

Theses and Dissertations

This paper examines how notions of textuality influence the production of William Shakespeare and Thomas Middleton's Timon of Athens in both scholarly, print editions and in theatrical performances of the play. It focuses specifically on the scenes involving Timon's epitaph, which have proven difficult to handle both editorially and theatrically, and seeks to show how changing views of the nature of textuality has significantly altered the way that different readers and audiences encounter this play. These issues regarding the idea of textuality begin with the play itself, which enacts its own ideas about the power of texts to intervene in …

Student Organization Advisors 2014-15, Office Of Registrar

Materials from All Student Organizations

No abstract provided.

A Judges's Perspective On Perspectives Courses: Three Suggested Rubrics…With Examples, Stephen J. Fortunato Jr.

Roger Williams University Law Review

No abstract provided.

Conformational Changes And Translocation Of Tissue-Transglutaminase To The Plasma Membranes: Role In Cancer Cell Migration, Ambrish Kumar, Jianjun Hu, Holly A. Lavoie, Kenneth B. Walsh, Donald J. Dipette, Ugra S. Singh

Faculty Publications

Background

Tissue-transglutaminase (TG2), a dual function G-protein, plays key roles in cell differentiation and migration. In our previous studies we reported the mechanism of TG2-induced cell differentiation. In present study, we explored the mechanism of how TG2 may be involved in cell migration.

Methods

To study the mechanism of TG2-mediated cell migration, we used neuroblastoma cells (SH-SY5Y) which do not express TG2, neuroblastoma cells expressing exogenous TG2 (SHY_TG2), and pancreatic cancer cells which express high levels of endogenous TG2. Resveratrol, a natural compound previously shown to inhibit neuroblastoma and pancreatic cancer in the animal models, was utilized to …

Toward A Framework For Levels Of Robot Autonomy In Human-Robot Interaction, Jenay Beer, A. D. Fisk, W. A. Rogers

Faculty Publications

Autonomy is a critical construct related to human-robot interaction (HRI) and varies widely across robot platforms. Levels of robot autonomy (LORA), ranging from teleoperation to fully autonomous systems, influence the way in which humans and robots interact with one another. Thus, there is a need to understand HRI by identifying variables that influence—and are influenced by—robot autonomy. Our overarching goal is to develop a framework for LORA in HRI. To reach this goal, our framework draws links between HRI and human-automation interaction, a field with a long history of studying and understanding human-related variables. The construct of autonomy is reviewed …

Ballet | La Soirée Des Animaux, John Craton

Craton Scores Collection

Les papillons -- L'our -- Le cygne -- Les chauves-sauris -- Le singes -- Mars des suricates -- Les reptiles -- Les kangourous -- La gazelle -- Le lion -- La grande valse de tous les animaux

Learning And Phototaxis In Belostoma Flumineum, Kaitlin Ann Garvey

Theses, Dissertations and Culminating Projects

Learning allows organisms to adjust their behavior to adapt to a changing environment. The premise of this study was to investigate the capacity for learning in the giant waterbug, Belostoma flumineum Say (Heteroptera: Belostomatidae). As part of these experiments, I was able to identify an apparent directional phototaxis and to use it as motivation in an operant conditioning study. Belostoma flumineum and has been observed to exhibit negative directional phototaxis. The first two parts of this study suggest that B. flumineum has a statistically significant preference for shadowed over illuminated areas, as well as a preference for black substrate over …

Common Sunflower Seedling Emergence Across The U.S. Midwest, Sharon A. Clay, Adam Davis, Anita Dille, John Lindquist, Analiza H. M. Ramirez, Christy Sprague, Graig Reicks, Frank Forcella

Department of Agronomy and Horticulture: Faculty Publications

Predictions of weed emergence can be used by practitioners to schedule POST weed management operations. Common sunflower seed from Kansas was used at six Midwestern U.S. sites to examine the variability that 16 climates had on common sunflower emergence. Nonlinear mixed effects models, using a flexible sigmoidal Weibull function that included thermal time, hydrothermal time, and a modified hydrothermal time (with accumulation starting from January 1 of each year), were developed to describe the emergence data. An iterative method was used to select an optimal base temperature (T_b) and base and ceiling soil matric potentials (ψ_b and …

Genotyping By Sequencing For Genomic Prediction In A Soybean Breeding Population, Diego Jarquin, Kyle Kocak, Luis Posadas, Katie Hyma, Joseph Jedlicka, George L. Graef, Aaron Lorenz

Department of Agronomy and Horticulture: Faculty Publications

Background: Advances in genotyping technology, such as genotyping by sequencing (GBS), are making genomic prediction more attractive to reduce breeding cycle times and costs associated with phenotyping. Genomic prediction and selection has been studied in several crop species, but no reports exist in soybean. The objectives of this study were (i) evaluate prospects for genomic selection using GBS in a typical soybean breeding program and (ii) evaluate the effect of GBS marker selection and imputation on genomic prediction accuracy. To achieve these objectives, a set of soybean lines sampled from the University of Nebraska Soybean Breeding Program were genotyped using …

Distillers Grains Supplementation In A Forage System With Spayed Heifers, Kari L. Gillespie, Terry J. Klopfenstein, James C. Macdonald Donald, Brandon L. Nuttelman, Cody J. Schneider, Jerry D. Volesky, Galen Erickson

Nebraska Beef Cattle Reports

Spayed heifers were developed into yearlings by grazing corn residue and bromegrass, followed by native range, and were finished on a common diet. Treatments were 2 lb or 5 lb of wet distillers grains with solubles (WDGS; DM basis) supplement on corn residue daily, and modified distillers grains with solubles (MDGS) fed at 0.6% BW daily or no MDGS during summer grazing. Feeding 5 lb increased winter ADG by 0.68 lb (year 1) or 0.40 lb (year 2) compared to 2 lb, and increased HCW after finishing. Summer supplementation increased summer ADG by 0.50 lb (year 1) or 0. 44 …

Feeding Elevated Levels Of Corn Silage And Mdgs In Finishing Diets, Dirk B. Burken, Brandon L. Nuttelman, Terry J. Klopfenstein Klopfenstein, Galen E. Erickson

Nebraska Beef Cattle Reports

A finishing experiment evaluatedsubstitution of corn silage and modified distillers grains with solubles (MDGS) in place of corn. The treatment arrangementwas a 2 X 2 + 1 factorial with 15 or 45% corn silage and 20 or 40% MDGS plus a control containing 5% cornstalks and 40% MDGS. There were interactions between corn silage and MDGS for carcass adjusted performance. As corn silage inclusion was increased in the diet, F:G increased when fed with 20% MDGS, however there was no difference when fed with 40% MDGS.

Evaluating Corn Condensed Distillers Solubles Concentration In Steam-Flaked Corn Finishing Diets On Cattle Performance And Carcass Characteristics, Marie E. Harris, Galen E. Erickson, Karla H. Jenkins Jenkins, Matt K. Luebbe

Nebraska Beef Cattle Reports

Performance and carcass characteristics were evaluated using five concentrations of corn condensed distillers solubles (CCDS) replacing steam-flaked corn (SFC) in feedlot finishing diets using crossbred steers. As CCDS replaced SFC at concentrations of 0, 9, 18, 27, or 36% of the diet DM, DMI decreased quadratically. Average daily gain increased quadratically with greatest gains observed at 27% CCDS inclusion. A quadratic improvement was observed in F:G with optimum concentrations similar to what was observed for ADG at 27% CCDS inclusion. These results suggest corn condensed distillers solubles can effectively be used to replace SFC in feedlot finishing diets while improving …

Transitioning Cattle From Ramp® To A Finishing Diet On Feedlot Performance And Feed Intake Variance, Cody J. Schneider, Brandon L. Nuttelman, Dirk B. Burken Burken, Terry J. Klopfenstein, Galen E. Erickson

Nebraska Beef Cattle Reports

Individually fed cattle were adapted to high grain diets with a traditional grain adaptation program or one of two RAMP^® adaptation programs. RAMP programs adapted cattle to a finishing diet gradually over 28 days in four steps or directly without an adaptation. Feed intake variance among d was greater for traditionally adapted cattle compared to either RAMP program, but DMI was not different during the adaptation period. Over the 138-day period, feedlot performance and carcass traits were not affected by adaptation treatment. Cattle fed RAMP for 10 days can be transitioned to a finishing ration containing 47.5% Sweet Bran …

Use Of A Pelleted Corn Residue Complete Feed In Receiving Diets, Sarah J. Peterson, Brandon L. Nuttelman, Dirk B. Burken Burken, James C. Macdonald, Matt K. Luebbe, Galen E. Erickson

Nebraska Beef Cattle Reports

The effects of feeding a complete pelleted feed to newly received steer calves (585 ± 4 lb; n = 1318 ) was compared to a control ration consisting of 32% (DM basis) wet or modified distillers grains, 32% alfalfa hay, 32% dry-rolled corn, and 4% supplement. The pelleted complete feed consisted of 35% corn residue and a blend of grain byproducts and minerals. Feeding the complete pelleted feed increased DMI but decreased ADG, thereby reducing feed efficiency. The pelleted feed numerically reduced morbidity. Feeding a complete pellet consisting of corn residue appears to be a viable option for receiving calves …

Comparison Of Long-Term Progestin-Based Synchronization Protocols On Fixed-Time Ai Pregnancy Rate In Beef Heifers, Rebecca A. Vraspir, Adam F. Summers, Doug O'Hare Hare, Larry D. Rowden, Rick N. Funston

Nebraska Beef Cattle Reports

Yearling Angus heifers at a commercial ranch in the Nebraska Sandhills were randomly assigned to one of two progestin-based fixed-time AI protocols (MGA or 14-day CIDR) to compare pregnancy rates. Heifers had similar fixed-time AI pregnancy rates between MGA and 14-day CIDR. A similar proportion of MGA and 14-day CIDR heifers displayed a second estrus; however, heifers previously synchronized with MGA tended to have a greater second AI pregnancy rate. Overall pregnancy rate was similar between MGA and 14-day CIDR treatments. The MGA system was the more cost effective synchronization protocol in this study.

Effect Of Feeding De-Oiled Wet Distillers Grains Plus Solubles On Beef Oxidation And Tenderness, Katherine I. Domenech, Kim A. Varnold, Michelle E. Semler, Michael D. Chao, Tommi F. Jones, Galen E. Erickson, Chris R. Calkins

Nebraska Beef Cattle Reports

Cattle fed a de-oiled wet distiller’s grains plus solubles (WDGS) diet were compared to cattle fed corn or traditional (full-fat) WDGS diets to determine effects on discoloration, oxidation, and tenderness of beef aged for seven and 21 days. At seven days of aging, dietary treatment had no effect on discoloration. At 21 days of aging, beef from cattle fed de-oiled WDGS had less oxidation than the corn control and several of the full-fat WDGS treatments. Although tenderness increased with aging and retail display, dietary treatment had no effect on tenderness. These findings suggest that these dietary treatments, followed by a …

Effect Of Feeding Different Types Of Byproducts And Concentrations Throughout A Beef Growing System On Ground Beef Color And Lipid Oxidation, Joe O. Buntyn, Brandy D. Cleveland, Amy L. Redfield Redfield, James C. Macdonald, Galen E. Erickson, Tommi F. Jones, Ty B. Schmidt, Gary A. Sullivan

Nebraska Beef Cattle Reports

The objective of this trial was to evaluate the effect of feeding different concentrations of wet distillers grains during winter backgrounding and either modified wet distillers grains or Sweet Bran^® during the finishing phase on ground beef color and lipid oxidation. After a 14 day aging period, ground beef patties were made and placed in a simulated retail display for seven days. There were no overall differences in lipid oxidation between treatments but was a treatment by day interaction for discoloration. Ground beef from heifers finished with modified wet distillers grains discolored at a greater extent when compared to …

Shelf Life Of Cooked Ground Beef Patties From Cattle Fed Wet Distillers Grains With Solubles, Nathan T. Dierks, Tommi F. Jones, Kimberly A. Varnold Varnold, Derek J. Schroeder, Amy L. Redfield, Gary A. Sullivan

Nebraska Beef Cattle Reports

Cattle were grazed without or with energy supplementation of wet distillers grains with solubles (WDGS) during backgrounding, and were finished on a corn-based diet with or without 35% WDGS. Ground beef patties were made from shoulder clods, cooked, and stored in a refrigerated or frozen state. Cattle supplemented with WDGS had greater lipid oxidation in cooked ground beef patties regardless of finishing diet or storage type.

Differences In Fecal Bacterial Community Composition Between Beef Steers Which Are High-Shedders And Low-Shedders Of Shiga Toxin-Producing Escherichia Coli (Stec), Nirosh D. Aluthge, Yoshitha A. Wanniarachchi, Brandon L. Nuttelman Nuttelman, Cody J. Schneider, Terry J. Klopfenstein, Galen E. Erickson, Samodha C. Fernando

Nebraska Beef Cattle Reports

The community composition of the fecal microbiota was compared between beef steers which were high-shedders and low-shedders of Shiga toxin-producing Escherichia coli. Based on Shannon and Chao 1 diversity indices, the high-shedders had a more diverse fecal bacterial community than the low-shedding steers. Members of the genus Prevotella were observed as being more abundant in the low-shedders compared to the high-shedders, while Succinivibrio were more abundant in the high-shedders. Isolation of specific bacteria which are significantly more abundant in low-shedders may pave the way to developing direct-fed microbials which are effective in reducing STEC shedding among high-shedding beef steers.