Digital Commons Network^™

The Pou Factor Ventral Veins Lacking/Drifter Directs The Timing Of Metamorphosis Through Ecdysteroid And Juvenile Hormone Signaling, Cece Cheng, Amy Ko, Leila Chaieb, Takashi Koyama, Prioty Sarwar, Christen K. Mirth, Wendy A. Smith, Yuichiro Suzuki

Faculty Research and Scholarship

Although endocrine changes are known to modulate the timing of major developmental transitions, the genetic mechanisms underlying these changes remain poorly understood. In insects, two developmental hormones, juvenile hormone (JH) and ecdysteroids, are coordinated with each other to induce developmental changes associated with metamorphosis. However, the regulation underlying the coordination of JH and ecdysteroid synthesis remains elusive. Here, we examined the function of a homolog of the vertebrate POU domain protein, Ventral veins lacking (Vvl)/Drifter, in regulating both of these hormonal pathways in the red flour beetle, Tribolium castaneum (Tenebrionidae). RNA interference-mediated silencing of vvlexpression led to both precocious …

Breaking Constraint: Axial Patterning In Trichechus (Mammalia: Sirenia), Emily A. Buchholtz, Kaisa L. Wayrynen, Iris W. Lin

Faculty Research and Scholarship

Meristic variation is often limited in serially homologous systems with high internal differentiation and high developmental modularity. The mammalian neck, an extreme example, has a fixed (at seven) count of diversely specialized segments. Imposition of the mammalian cervical constraint has been tentatively linked to the origin of the diaphragm, which is muscularized by cells that migrate from cervical somites during development. With six cervical vertebrae, the genus Trichechus (manatee) has apparently broken this constraint, although the mechanism of constraint escape is unknown. Hypotheses for the developmental origin of Trichechus cervical morphology include cervical rib 7 repatterning, a primaxial/abaxial patterning shift, …

Imaginary Companions And Young Children's Coping And Competence, Tracy R. Gleason, Maria Kalpidou

Faculty Research and Scholarship

Imaginary companions (ICs) are purported to bolster children’s coping and self-competence, but few studies address this claim. We expected having/not having ICs would distinguish children’s coping strategies and competence less than type of companion (i.e., personified object or invisible friend) or quality of child-IC relationship (i.e., egalitarian or hierarchical). We interviewed 72 3- to 6-year-olds and their mothers about children’s coping strategies and competence; teachers rated competence. Mothers reported ICs. IC presence and type did not differentiate coping strategies, but children with egalitarian relationships chose more constructive/prosocial coping strategies, and teachers rated them more socially competent than children with hierarchical …

Hume And The Metaphysics Of Agency, Joshua M. Wood

Faculty Research and Scholarship

No abstract provided.

Identity Unthroned: Fallen Sublimity In John Keats’ Hyperion, William Shakespeare’S King Lear, And John Milton’S Paradise Lost, Sydney Cusack

Honors Thesis Collection

The works of Keats, Shakespeare and Milton all contain figures fallen from power and grace: Saturn in Hyperion, Lear in King Lear, and Satan Paradise Lost. After the fall, what remains? In this examination, I intend to examine the aftermath of each character's fall from power, including what happens to his sublimity, the dissonance (or concord) between his self-perception and his perception by others, and the consequences of shifts in the locus of his power. Despite their different circumstances, Saturn, Lear, and Satan have much in common as fall powers, their unthroned identities lost, "somewhere between the throne, and where …

The Rag And Bone Shop Of The Heart: Tracking The Development Of William Butler Yeats’S Poetry Through Manuscript Materials, Kelly Anne Mccullagh

Honors Thesis Collection

No abstract provided.

The Fatal Art: Hemingway And The Bullfight, Stephanie Gall

Honors Thesis Collection

No abstract provided.

"You Got To Do The Thing With Soul": Sam Cooke And Soul Music In America, Madeline Buckley

Honors Thesis Collection

No abstract provided.

Lady, Lisa Ventura

Honors Thesis Collection

No abstract provided.

Je Est Un Autre: Memory, Self, And The Autobiographic Text, Constance Chien

Honors Thesis Collection

No abstract provided.

Preparation Of Analogs Of The Glp-1 Receptor Inverse Agonist, T-0632, Emily Wilson

Honors Thesis Collection

No abstract provided.

Altruism: A Natural Thought History Of An Idea, Caroline Golub

Honors Thesis Collection

This thesis explores the numerous definitions and ideas surrounding the term altruism, tracking it from its origins in sociology, to the ways in which it has been interpreted across disciplines.

21st Century Orientals: The Displacement Of Eastern Identities In Contemporary Hollywood Adaptation, Annie Wang

Honors Thesis Collection

In an increasingly globalized world, contemporary Hollywood has capitalized on sustained interest in Eastern cultures in the West by adapting popular novels, television shows, video games, and graphic novels into big budget, feature-length films with all-star casts headed by some of the world’s most acclaimed directors. However, such adaptations have historically been mired in racially-charged stereotypes that displace and absent Asian bodies and voices from American popular visual media.

This thesis examines how recent fantasy-adventure blockbusters such as ‘Prince of Persia: The Sands of Time’ (2010, dir. Mike Newell), ‘The Last Airbender’ (2010, dir. M. Night Shyamalan), and ‘Cloud Atlas’ …

Differentially Expressed Pr-A And Pr-B Are Co-Localized With Src-1 And Src-2 In The Female Mouse Hypothalamus, Sarah Finkelstein

Honors Thesis Collection

No abstract provided.

The Stone Monkey, Wendy Chen

Honors Thesis Collection

No abstract provided.

Wellesley Magazine Fall 2014, Wellesley College Alumnae Association

Wellesley Magazine (Alumnae Association)

Featured in this issue:

Wendy Posts It / by Sarah Ligon ’03

Blue on the Red Planet / by Lisa Scanlon Mogolov ’99

Rewriting the Book on Clapp Library / by Catherine O'Neill Grace

Phenoxybenzamine Is Neuroprotective In A Rat Model Of Severe Traumatic Brain Injury, Thomas Rau, Aakriti Kothiwal, Annela Rova, Joseph F. Rhoderick, David J. Poulsen

Biomedical and Pharmaceutical Sciences Faculty Publications

Phenoxybenzamine (PBZ) is an FDA approved α-1 adrenergic receptor antagonist that is currently used to treat symptoms of pheochromocytoma. However, it has not been studied as a neuroprotective agent for traumatic brain injury (TBI). While screening neuroprotective candidates, we found that phenoxybenzamine reduced neuronal death in rat hippocampal slice cultures following exposure to oxygen glucose deprivation (OGD). Using this system, we found that phenoxybenzamine reduced neuronal death over a broad dose range (0.1 μM–1 mM) and provided efficacy when delivered up to 16 h post-OGD. We further tested phenoxybenzamine in the rat lateral fluid percussion model of TBI. When administered …

Lithics In The West: Using Lithic Analysis To Solve Archeological Problems In Western North America, Douglas H. Macdonald, William Andrefsky Jr., Pei-Lin Yu

UM Press Open Access Books

Lithics in the West seeks to link the rich archaeological lithic data base from the western United States with some of the contemporary theoretical and analytical approaches used in global settings in stone tool and debitage analysis today. The book highlights the role that lithic analysis (in all its forms) plays in solving research problems in the prehistory of western North America. The book covers important archaeological sites and projects in Montana, Wyoming, Idaho, Colorado, and Washington.

Contributors include William Andrefsky, Jr., Robert Kelly, Nicole Waguespack, Pei-Lin Yu, Doug MacDonald, Robert Brunswig, Scott Carpenter, Jackie Cook, David Diggs, Philip Fisher, …

The Hunt For Privacy Under The Big Sky, University Of Montana--Missoula. School Of Journalism

Montana Journalism Review

Watchdog: Kiss and Tell -- Making the Cut -- Capturing the Moment -- Digging on Deadline -- University Confidential -- Concealed Weapons -- The Birthday Loophole

Secrets: Behind the Times -- No Place to Hide -- Privacy Betrayed -- Under the Needle -- Editorial Cartoon -- The Grind -- One Frame Every Day

Made in Montana: Spying on Wildlife -- The Secret to YouTube Success -- Preaching to the Choir -- Gaps on the Map -- Native Secrets -- Secret Montana Fantasies -- Towner's Gold -- Facebook Confessionals

The Year Ahead: The Hit List -- J-School Confidential -- After Jaffe …

Heritage Hog Carcass Yields: American Guinea Hog, Bob Perry

Heritage Hog Carcass Yields

The saleable yield of the Guinea Hog, cut in the American style, is 66%. The overall percentage of lean muscle using the industry formula based on backfat at 1st and 10th rib, loin eye area and hot carcass weight is 24%. Cut for Charcuterie, the saleable yield is 69%.

Annual Report For The Town Of Hebron, New Hampshire For The Fiscal Year Ending December 31, 2013., Hebron Town Representatives

Hebron, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

Town Of Henniker, New Hampshire Annual Report Of The Town Offices For The Fiscal Year Ending December 31, 2013., Henniker Town Representatives

Henniker, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

Town Of Hanover, New Hampshire Annual Report For The Fiscal Year Ending June 30, 2014 And 2015 Town Meeting., Hanover Town Representatives

Hanover, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

Annual Report Of The Town Officers For The Fiscal Year Ending December 31, 2013., Gilmanton Town Representatives

Gilmanton, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

Annual Report Of The Selectmen/Auditors, Town Clerk/Tax Collector, Town Treasurer, Road Agent/Trustees Of The Trust Funds, Trustees Of The Library, Planning Board, Police And Fire Departments, Board Of Education, Town Of Hampstead, New Hampshire For The Year Ending December 31, 2013 Together With The Vital Statistics For The Year As Prepared By The Town Clerk., Hampstead Town Representatives

Hampstead, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

Hopkinton Annual Reports 2013, Town Of Hopkinton, Hopkinton School District., Hopkinton Town Representatives

Hopkinton, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

Role Of Bumetanide On Insulin Secretion, Mohammed Mashari Almutairi

Browse all Theses and Dissertations

Insulin secretion depends on the electrical properties of the ß-cells in pancreatic islets. The consensus mechanism of insulin secretion involves glucose-stimulated metabolic increase in the ATP/ADP ratio. This increase closes ATP-sensitive K+ (KATP) channels resulting in ß-cell plasma membrane depolarization, which in turn activates voltage-dependent Ca2+ channels further resulting in Ca2+ influx and release of insulin stored in granules. In addition to this well-known consensus mechanism, insulin secretion also depends on electrogenic efflux of Cl- ions. The Na+K 2Cl- cotransporters (NKCCs) maintain the intracellular concentration of Cl- ([Cl-]i) at values higher than those predicted at thermodynamic equilibrium. This distribution of …

A Distributed Model Of Oilseed Biorefining, Via Integrated Industrial Ecology Exchanges, Jeremy C. Ferrell

Dissertations

As the demand for direct petroleum substitutes increases, biorefineries are poised to become centers for conversion of biomass into fuels, energy, and biomaterials. A distributed model offers reduced transportation, tailored process technology to available feedstock, and increased local resilience. Oilseeds are capable of producing a wide variety of useful products additive to food, feed, and fuel needs. Biodiesel manufacturing technology lends itself to smaller-scale distributed facilities able to process diverse feedstocks and meet demand of critical diesel fuel for basic municipal services, safety, sanitation, infrastructure repair, and food production. Integrating biodiesel refining facilities as tenants of eco-industrial parks presents a …

Recent Accomplishments Factsheet: 2014, Casco Bay Estuary Partnership

Publications

Through collaboration with its partners, the Casco Bay Estuary Partnership (CBEP) is devoted to protecting and restoring the water quality and fish and wildlife habitat of the Casco Bay ecosystem, while ensuring compatible human uses. Casco Bay is one of 28 “estuaries of national significance” designated by the U.S. Environmental Protection Agency.

Hillsborough County, New Hampshire F/Y 2014 Annual Report., Hillsborough County Representatives

Hillsborough County, NH Annual Reports

This is an annual report containing vital statistics for a county in the state of New Hampshire.